#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35433	uniprotkb:O35433	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Liao et al. (2013)	pubmed:24305160|doi:10.1038/nature12822|imex:IM-21933	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16084104|imex:IM-21933-1|dip:DIP-192554E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rigid:WXAvVMV+/SuEf9ksB7hIiTc1Wsk	false	sufficient binding region:627-764,110-603	sufficient binding region:627-764,110-603	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35433	uniprotkb:O35433	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Liao et al. (2013)	pubmed:24305160|doi:10.1038/nature12822|imex:IM-21933	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16084124|imex:IM-21933-2|dip:DIP-192554E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rigid:WXAvVMV+/SuEf9ksB7hIiTc1Wsk	false	sufficient binding region:627-764,110-603	sufficient binding region:627-764,110-603	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35433	uniprotkb:O35433	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:"MI:0020"(transmission electron microscopy)	Liao et al. (2013)	pubmed:24305160|doi:10.1038/nature12822|imex:IM-21933	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16084143|imex:IM-21933-3|dip:DIP-192554E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rigid:WXAvVMV+/SuEf9ksB7hIiTc1Wsk	false	sufficient binding region:627-764,110-603	sufficient binding region:627-764,110-603	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)