#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75899 uniprotkb:Q9UBS5-2 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 intact:EBI-16084001|ensembl:ENSP00000348248|ensembl:ENSP00000366211|ensembl:ENSP00000373029|ensembl:ENSP00000373035|ensembl:ENSP00000373132|ensembl:ENSP00000373135|ensembl:ENSP00000391572|ensembl:ENSP00000394528|ensembl:ENSP00000405709|ensembl:ENSP00000406285|ensembl:ENSP00000406499|ensembl:ENSP00000408938|ensembl:ENSP00000411263|ensembl:ENSP00000416903 psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:q9ubs5-2(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Geng et al. (2013) pubmed:24305054|doi:10.1038/nature12725|imex:IM-21935 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16084007|imex:IM-21935-1|dip:DIP-72955E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237051(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000355973(transcript)|ensembl:ENST00000377012(transcript)|ensembl:ENST00000383537(transcript)|ensembl:ENST00000383543(transcript)|ensembl:ENST00000383636(transcript)|ensembl:ENST00000383639(transcript)|ensembl:ENST00000414980(transcript)|ensembl:ENST00000417759(transcript)|ensembl:ENST00000438094(transcript)|ensembl:ENST00000446436(transcript)|ensembl:ENST00000448754(transcript)|ensembl:ENST00000449163(transcript)|ensembl:ENST00000452300(transcript)|ensembl:ENST00000458612(transcript)|intact:EBI-724156(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 rogid:chWam/MNJlKN34T43KCV+qHbMoo9606 rigid:1aof/J+l08XrHc61ic09roXlZnc false mutation:206-206|ha tag:n-n mutation:198-198|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75899 uniprotkb:Q9UBS5-2 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 intact:EBI-16084001|ensembl:ENSP00000348248|ensembl:ENSP00000366211|ensembl:ENSP00000373029|ensembl:ENSP00000373035|ensembl:ENSP00000373132|ensembl:ENSP00000373135|ensembl:ENSP00000391572|ensembl:ENSP00000394528|ensembl:ENSP00000405709|ensembl:ENSP00000406285|ensembl:ENSP00000406499|ensembl:ENSP00000408938|ensembl:ENSP00000411263|ensembl:ENSP00000416903 psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:q9ubs5-2(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Geng et al. (2013) pubmed:24305054|doi:10.1038/nature12725|imex:IM-21935 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16084036|imex:IM-21935-2|dip:DIP-72955E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237051(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000355973(transcript)|ensembl:ENST00000377012(transcript)|ensembl:ENST00000383537(transcript)|ensembl:ENST00000383543(transcript)|ensembl:ENST00000383636(transcript)|ensembl:ENST00000383639(transcript)|ensembl:ENST00000414980(transcript)|ensembl:ENST00000417759(transcript)|ensembl:ENST00000438094(transcript)|ensembl:ENST00000446436(transcript)|ensembl:ENST00000448754(transcript)|ensembl:ENST00000449163(transcript)|ensembl:ENST00000452300(transcript)|ensembl:ENST00000458612(transcript)|intact:EBI-724156(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/07 2017/08/10 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 rogid:chWam/MNJlKN34T43KCV+qHbMoo9606 rigid:1aof/J+l08XrHc61ic09roXlZnc false sufficient binding region:1-466 sufficient binding region:48-459 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75899 uniprotkb:Q9UBS5-2 intact:EBI-715469|uniprotkb:O75974|uniprotkb:O75975|uniprotkb:Q5VXZ2|uniprotkb:Q8WX04|uniprotkb:Q9P1R2|uniprotkb:Q9UNR1|uniprotkb:Q9UNS9|ensembl:ENSP00000259455 intact:EBI-16084001|ensembl:ENSP00000348248|ensembl:ENSP00000366211|ensembl:ENSP00000373029|ensembl:ENSP00000373035|ensembl:ENSP00000373132|ensembl:ENSP00000373135|ensembl:ENSP00000391572|ensembl:ENSP00000394528|ensembl:ENSP00000405709|ensembl:ENSP00000406285|ensembl:ENSP00000406499|ensembl:ENSP00000408938|ensembl:ENSP00000411263|ensembl:ENSP00000416903 psi-mi:gabr2_human(display_long)|uniprotkb:G-protein coupled receptor 51(gene name synonym)|uniprotkb:HG20(gene name synonym)|uniprotkb:GABBR2(gene name)|psi-mi:GABBR2(display_short)|uniprotkb:GPR51(gene name synonym)|uniprotkb:GPRC3B(gene name synonym) psi-mi:q9ubs5-2(display_long)|uniprotkb:GABBR1(gene name)|psi-mi:GABBR1(display_short)|uniprotkb:GPRC3A(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Geng et al. (2013) pubmed:24305054|doi:10.1038/nature12725|imex:IM-21935 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16084066|imex:IM-21935-3|dip:DIP-72955E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005449.5|ensembl:ENSG00000136928(gene)|ensembl:ENST00000259455(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR041689|mint:O75899|rcsb pdb:4F11|rcsb pdb:4F12|rcsb pdb:4MQE|rcsb pdb:4MQF|rcsb pdb:4MR7|rcsb pdb:4MR8|rcsb pdb:4MR9|rcsb pdb:4MRM|rcsb pdb:4MS1|rcsb pdb:4MS3|rcsb pdb:4MS4|rcsb pdb:4PAS|rcsb pdb:6M8R|rcsb pdb:6OCP|rcsb pdb:6UO8|rcsb pdb:6UO9|rcsb pdb:6UOA|rcsb pdb:6VJM|rcsb pdb:6W2X|rcsb pdb:6WIV|rcsb pdb:7C7Q|rcsb pdb:7C7S|rcsb pdb:7CA3|rcsb pdb:7CA5|rcsb pdb:7CUM|rcsb pdb:7EB2|reactome:R-HSA-1296041|reactome:R-HSA-418594|reactome:R-HSA-420499|reactome:R-HSA-977444|reactome:R-HSA-997272|dip:DIP-42851N ensembl:ENSG00000204681(gene)|ensembl:ENSG00000206466(gene)|ensembl:ENSG00000206511(gene)|ensembl:ENSG00000232569(gene)|ensembl:ENSG00000232632(gene)|ensembl:ENSG00000237051(gene)|ensembl:ENSG00000237112(gene)|ensembl:ENST00000355973(transcript)|ensembl:ENST00000377012(transcript)|ensembl:ENST00000383537(transcript)|ensembl:ENST00000383543(transcript)|ensembl:ENST00000383636(transcript)|ensembl:ENST00000383639(transcript)|ensembl:ENST00000414980(transcript)|ensembl:ENST00000417759(transcript)|ensembl:ENST00000438094(transcript)|ensembl:ENST00000446436(transcript)|ensembl:ENST00000448754(transcript)|ensembl:ENST00000449163(transcript)|ensembl:ENST00000452300(transcript)|ensembl:ENST00000458612(transcript)|intact:EBI-724156(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/07 2017/08/10 rogid:vJ8ADZ7mdufBs4z/z0Zy4TzN3Sw9606 rogid:chWam/MNJlKN34T43KCV+qHbMoo9606 rigid:1aof/J+l08XrHc61ic09roXlZnc false sufficient binding region:1-466 sufficient binding region:48-459 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)