#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q06141 uniprotkb:Q06141 intact:EBI-10223932|ensembl:ENSP00000304311|ensembl:ENSP00000377456|ensembl:ENSP00000386630 intact:EBI-10223932|ensembl:ENSP00000304311|ensembl:ENSP00000377456|ensembl:ENSP00000386630 psi-mi:reg3a_human(display_long)|uniprotkb:REG3A(gene name)|psi-mi:REG3A(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:Hepatointestinal pancreatic protein(gene name synonym)|uniprotkb:Human proislet peptide(gene name synonym)|uniprotkb:PAP(gene name synonym)|uniprotkb:PAP1(gene name synonym)|uniprotkb:Pancreatitis-associated protein 1(gene name synonym)|uniprotkb:Regenerating islet-derived protein III-alpha(gene name synonym) psi-mi:reg3a_human(display_long)|uniprotkb:REG3A(gene name)|psi-mi:REG3A(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:Hepatointestinal pancreatic protein(gene name synonym)|uniprotkb:Human proislet peptide(gene name synonym)|uniprotkb:PAP(gene name synonym)|uniprotkb:PAP1(gene name synonym)|uniprotkb:Pancreatitis-associated protein 1(gene name synonym)|uniprotkb:Regenerating islet-derived protein III-alpha(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Mukherjee et al. (2014) pubmed:24256734|doi:10.1038/nature12729|imex:IM-22355 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16082124|imex:IM-22355-1|dip:DIP-195896E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002571.1|refseq:NP_620354.1|refseq:NP_620355.1|ensembl:ENSG00000172016(gene)|ensembl:ENST00000409839(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006953"(acute-phase response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044278"(cell wall disruption in another organism)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:1UV0|rcsb pdb:2GO0|rcsb pdb:4MTH|reactome:R-HSA-6803157|ensembl:ENST00000305165(transcript)|ensembl:ENST00000393878(transcript)|dip:DIP-60688N refseq:NP_002571.1|refseq:NP_620354.1|refseq:NP_620355.1|ensembl:ENSG00000172016(gene)|ensembl:ENST00000409839(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006953"(acute-phase response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044278"(cell wall disruption in another organism)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:1UV0|rcsb pdb:2GO0|rcsb pdb:4MTH|reactome:R-HSA-6803157|ensembl:ENST00000305165(transcript)|ensembl:ENST00000393878(transcript)|dip:DIP-60688N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1SImXM+nzRh1PZ5zxZOMq1+zAuU9606 rogid:1SImXM+nzRh1PZ5zxZOMq1+zAuU9606 rigid:ugSL4VVMfat6X7Do9MObCxTe3Uo false sufficient binding region:38-175 sufficient binding region:38-175 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06141 uniprotkb:Q06141 intact:EBI-10223932|ensembl:ENSP00000304311|ensembl:ENSP00000377456|ensembl:ENSP00000386630 intact:EBI-10223932|ensembl:ENSP00000304311|ensembl:ENSP00000377456|ensembl:ENSP00000386630 psi-mi:reg3a_human(display_long)|uniprotkb:REG3A(gene name)|psi-mi:REG3A(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:Hepatointestinal pancreatic protein(gene name synonym)|uniprotkb:Human proislet peptide(gene name synonym)|uniprotkb:PAP(gene name synonym)|uniprotkb:PAP1(gene name synonym)|uniprotkb:Pancreatitis-associated protein 1(gene name synonym)|uniprotkb:Regenerating islet-derived protein III-alpha(gene name synonym) psi-mi:reg3a_human(display_long)|uniprotkb:REG3A(gene name)|psi-mi:REG3A(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:Hepatointestinal pancreatic protein(gene name synonym)|uniprotkb:Human proislet peptide(gene name synonym)|uniprotkb:PAP(gene name synonym)|uniprotkb:PAP1(gene name synonym)|uniprotkb:Pancreatitis-associated protein 1(gene name synonym)|uniprotkb:Regenerating islet-derived protein III-alpha(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Mukherjee et al. (2014) pubmed:24256734|doi:10.1038/nature12729|imex:IM-22355 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16082142|imex:IM-22355-2|dip:DIP-195896E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002571.1|refseq:NP_620354.1|refseq:NP_620355.1|ensembl:ENSG00000172016(gene)|ensembl:ENST00000409839(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006953"(acute-phase response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044278"(cell wall disruption in another organism)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:1UV0|rcsb pdb:2GO0|rcsb pdb:4MTH|reactome:R-HSA-6803157|ensembl:ENST00000305165(transcript)|ensembl:ENST00000393878(transcript)|dip:DIP-60688N refseq:NP_002571.1|refseq:NP_620354.1|refseq:NP_620355.1|ensembl:ENSG00000172016(gene)|ensembl:ENST00000409839(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006953"(acute-phase response)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044278"(cell wall disruption in another organism)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|rcsb pdb:1UV0|rcsb pdb:2GO0|rcsb pdb:4MTH|reactome:R-HSA-6803157|ensembl:ENST00000305165(transcript)|ensembl:ENST00000393878(transcript)|dip:DIP-60688N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:1SImXM+nzRh1PZ5zxZOMq1+zAuU9606 rogid:1SImXM+nzRh1PZ5zxZOMq1+zAuU9606 rigid:ugSL4VVMfat6X7Do9MObCxTe3Uo false sufficient binding region:38-175 sufficient binding region:38-175 - 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)