#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14676	uniprotkb:O76064-1	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	intact:EBI-15964690|ensembl:ENSP00000362578	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:o76064-1(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081882|imex:IM-21889-2|dip:DIP-66434E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	ensembl:ENSG00000112130(gene)|ensembl:ENST00000373479(transcript)|intact:EBI-373337(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	rigid:WM60t0Q5m3+wMkXQt7aGT5dnQwk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15652	intact:EBI-4399559	intact:EBI-1224969|uniprotkb:Q5SQZ8|uniprotkb:Q5SQZ9|uniprotkb:Q5SR00|uniprotkb:Q7Z3E7|uniprotkb:Q8N3U0|uniprotkb:Q96KB9|uniprotkb:Q9P2G7|uniprotkb:A0T124|intact:EBI-28967816|ensembl:ENSP00000382204	dip:DIP-24261N	psi-mi:jhd2c_human(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081863|imex:IM-21889-1|dip:DIP-192426E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001269877.1|refseq:NP_116165.1|ensembl:ENSP00000382204|ensembl:ENST00000542921|ensembl:ENSP00000444682|refseq:NP_001305082.1|refseq:NP_001305083.1|refseq:NP_001309181.1|refseq:NP_001309183.1|refseq:NP_001309187.1|refseq:XP_016871386.1|refseq:XP_016871387.1|dip:DIP-38114N|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007596"(blood coagulation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q15652|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)|go:"GO:0000118"(histone deacetylase complex)|rcsb pdb:2YPD|rcsb pdb:5FZO|reactome:R-HSA-983231	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:6sIE0LcPIoZUmjaxB+ZzDFaTv3s	false	-	flag tag:0-0	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14676	intact:EBI-4399559	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	dip:DIP-24261N	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081916|imex:IM-21889-4|dip:DIP-192428E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:233PxMvxP49P+u5kl3464wQLCew	false	-	flag tag:0-0	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14676	uniprotkb:Q96RL1-1	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	intact:EBI-9640371|ensembl:ENSP00000366434|ensembl:ENSP00000421926	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:q96rl1-1(display_long)|uniprotkb:UIMC1(gene name)|psi-mi:UIMC1(display_short)|uniprotkb:RXRIP110(gene name synonym)|uniprotkb:Receptor-associated protein 80(gene name synonym)|uniprotkb:Retinoid X receptor-interacting protein 110(gene name synonym)|uniprotkb:Ubiquitin interaction motif-containing protein 1(gene name synonym)|uniprotkb:RAP80(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081899|imex:IM-21889-3|dip:DIP-192430E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	ensembl:ENSG00000087206(gene)|ensembl:ENST00000377227(transcript)|ensembl:ENST00000511320(transcript)|intact:EBI-725300(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rogid:j5ho+aD4tkX7bXXlROdiprUX1Mc9606	rigid:vw0UILpXdFO23Bvw+z/xQfk6WNw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14676	uniprotkb:O76064-1	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	intact:EBI-15964690|ensembl:ENSP00000362578	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:o76064-1(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16082033|imex:IM-21889-9|dip:DIP-66434E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	ensembl:ENSG00000112130(gene)|ensembl:ENST00000373479(transcript)|intact:EBI-373337(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	rigid:WM60t0Q5m3+wMkXQt7aGT5dnQwk	false	ha tag:n-n	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15652-1	uniprotkb:O76064-1	intact:EBI-16081935|ensembl:ENSP00000382204	intact:EBI-15964690|ensembl:ENSP00000362578	psi-mi:q15652-1(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:o76064-1(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16082054|imex:IM-21889-10|dip:DIP-192427E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1224969(isoform-parent)|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)	ensembl:ENSG00000112130(gene)|ensembl:ENST00000373479(transcript)|intact:EBI-373337(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	rigid:BxMeaEeQUYFcYRRu095p8ZAw2iI	false	sufficient binding region:753-1162|flag tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q14676	uniprotkb:Q15652-1	intact:EBI-495644|uniprotkb:A2AB04|uniprotkb:A2BF04|uniprotkb:A2RRA8|uniprotkb:A7YY86|uniprotkb:B0S8A2|uniprotkb:Q0EFC2|uniprotkb:Q2L6H7|uniprotkb:Q2TAZ4|uniprotkb:Q5ST83|uniprotkb:Q68CQ3|uniprotkb:Q86Z06|uniprotkb:Q96QC2|uniprotkb:Q5JP55|uniprotkb:Q5JP56|ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000387429|ensembl:ENSP00000396484|ensembl:ENSP00000404318|ensembl:ENSP00000409167|ensembl:ENSP00000415212|ensembl:ENSP00000416511|intact:EBI-28978228	intact:EBI-16081935|ensembl:ENSP00000382204	psi-mi:mdc1_human(display_long)|uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)|uniprotkb:MDC1(gene name)|psi-mi:MDC1(display_short)|uniprotkb:KIAA0170(gene name synonym)|uniprotkb:NFBD1(gene name synonym)	psi-mi:q15652-1(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16082012|imex:IM-21889-8|dip:DIP-192431E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000365588|ensembl:ENSP00000373060|ensembl:ENSP00000396484|ensembl:ENSP00000416511|ensembl:ENSP00000387429|ensembl:ENSP00000404318|ensembl:ENSP00000415212|ensembl:ENSP00000409167|refseq:NP_055456.2|refseq:XP_011513303.1|refseq:XP_011513305.1|refseq:XP_005249551.1|dip:DIP-33603N|refseq:XP_016867008.1|ensembl:ENSG00000137337(gene)|ensembl:ENSG00000206481(gene)|ensembl:ENSG00000225589(gene)|ensembl:ENSG00000228575(gene)|ensembl:ENSG00000231135(gene)|ensembl:ENSG00000234012(gene)|ensembl:ENSG00000237095(gene)|ensembl:ENST00000376406(transcript)|ensembl:ENST00000383566(transcript)|ensembl:ENST00000420019(transcript)|ensembl:ENST00000420320(transcript)|ensembl:ENST00000427406(transcript)|ensembl:ENSG00000224587(gene)|ensembl:ENST00000435664(transcript)|ensembl:ENST00000440369(transcript)|ensembl:ENST00000449153(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0070975"(FHA domain binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001357(BRCT)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR036420|mint:Q14676|rcsb pdb:2ADO|rcsb pdb:2AZM|rcsb pdb:2ETX|rcsb pdb:3K05|rcsb pdb:3UEO|rcsb pdb:3UMZ|rcsb pdb:3UN0|rcsb pdb:3UNM|rcsb pdb:3UNN|rcsb pdb:3UOT|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-6796648|reactome:R-HSA-69473	intact:EBI-1224969(isoform-parent)|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:fkclTpFKHkxAjNuMuTmZRAigCa89606	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rigid:LKBIQfaLKho2oxaXeM2svPVeyS8	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15652-1	intact:EBI-4399559	intact:EBI-16081935|ensembl:ENSP00000382204	dip:DIP-24261N	psi-mi:q15652-1(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081989|imex:IM-21889-7|dip:DIP-192426E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1224969(isoform-parent)|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:6sIE0LcPIoZUmjaxB+ZzDFaTv3s	false	flag tag:?-?	myc tag:0-0	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O76064-1	uniprotkb:Q15652	intact:EBI-15964690|ensembl:ENSP00000362578	intact:EBI-1224969|uniprotkb:Q5SQZ8|uniprotkb:Q5SQZ9|uniprotkb:Q5SR00|uniprotkb:Q7Z3E7|uniprotkb:Q8N3U0|uniprotkb:Q96KB9|uniprotkb:Q9P2G7|uniprotkb:A0T124|intact:EBI-28967816|ensembl:ENSP00000382204	psi-mi:o76064-1(display_long)|uniprotkb:RNF8(gene name)|psi-mi:RNF8(display_short)|uniprotkb:KIAA0646(gene name synonym)|uniprotkb:RING finger protein 8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF8(gene name synonym)	psi-mi:jhd2c_human(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081972|imex:IM-21889-6|dip:DIP-192427E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000112130(gene)|ensembl:ENST00000373479(transcript)|intact:EBI-373337(isoform-parent)	refseq:NP_001269877.1|refseq:NP_116165.1|ensembl:ENSP00000382204|ensembl:ENST00000542921|ensembl:ENSP00000444682|refseq:NP_001305082.1|refseq:NP_001305083.1|refseq:NP_001309181.1|refseq:NP_001309183.1|refseq:NP_001309187.1|refseq:XP_016871386.1|refseq:XP_016871387.1|dip:DIP-38114N|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007596"(blood coagulation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q15652|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)|go:"GO:0000118"(histone deacetylase complex)|rcsb pdb:2YPD|rcsb pdb:5FZO|reactome:R-HSA-983231	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:nsYlZhRT5wsltOEjHh1l815IphQ9606	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rigid:BxMeaEeQUYFcYRRu095p8ZAw2iI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15652-1	intact:EBI-4399559	intact:EBI-16081935|ensembl:ENSP00000382204	dip:DIP-24261N	psi-mi:q15652-1(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16081947|imex:IM-21889-5|dip:DIP-192426E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1224969(isoform-parent)|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	psi-mi:"MI:0465"(dip)	-	no-uniprot-update:	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/15	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rigid:6sIE0LcPIoZUmjaxB+ZzDFaTv3s	false	flag tag:?-?|sufficient binding region:753-1162	ha tag:0-0	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8IYW5	uniprotkb:Q15652-1	intact:EBI-914207|uniprotkb:Q8NA67|uniprotkb:Q96NS4|intact:EBI-28968912|ensembl:ENSP00000320898	intact:EBI-16081935|ensembl:ENSP00000382204	psi-mi:rn168_human(display_long)|uniprotkb:RNF168(gene name)|psi-mi:RNF168(display_short)|uniprotkb:RING-type E3 ubiquitin transferase RNF168(gene name synonym)|uniprotkb:RING finger protein 168(gene name synonym)	psi-mi:q15652-1(display_long)|uniprotkb:JMJD1C(gene name)|psi-mi:JMJD1C(display_short)|uniprotkb:JHDM2C(gene name synonym)|uniprotkb:KIAA1380(gene name synonym)|uniprotkb:TRIP8(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1C(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Watanabe et al. (2013)	pubmed:24240613|doi:10.1038/nsmb.2702|imex:IM-21889	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16082079|imex:IM-21889-11|dip:DIP-192429E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000163961(gene)|ensembl:ENST00000318037(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036351"(histone H2A-K13 ubiquitination)|go:"GO:0036352"(histone H2A-K15 ubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045190"(isotype switching)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070535"(histone H2A K63-linked ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034725|mint:Q8IYW5|rcsb pdb:3L11|rcsb pdb:4GB0|rcsb pdb:5XIS|rcsb pdb:5XIT|rcsb pdb:5XIU|rcsb pdb:5YDK|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|ensembl:ENSP00000320898|refseq:NP_689830.2|dip:DIP-37451N	intact:EBI-1224969(isoform-parent)|ensembl:ENSG00000171988(gene)|ensembl:ENST00000399262(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:FTUGOdIMWBYvqjBfeyEsFKJsQtc9606	rogid:15Klx5csF2CGH8c1YZBcVfhxCac9606	rigid:sawHYfSDGl8+41U9P7Kemu/VBGU	false	glutathione s tranferase tag:n-n	sufficient binding region:753-1162|flag tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)