#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32529 uniprotkb:P50106 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15750|uniprotkb:D6VSD7|ensemblfungi:YDR156W psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpa14_yeast(display_long)|uniprotkb:RPA14(gene name)|psi-mi:RPA14(display_short)|uniprotkb:YDR156W(locus name)|uniprotkb:YD8358.11(orf name)|uniprotkb:DNA-directed RNA polymerase I 14 kDa polypeptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_010440.1|sgd:S000002563|ensemblfungi:YDR156W(gene)|ensemblfungi:YDR156W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013239(RNA polymerase I, subunit RPA14, fungi)|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:6RWE|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6TPS|dip:DIP-2053N|mint:P50106 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:D2318636ABDE68B9 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:fIDAOOpJrLwSXy7vygwP4Cu96Ww559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P10964 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15730|uniprotkb:Q99330|uniprotkb:D6W336|ensemblfungi:YOR341W psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpa1_yeast(display_long)|uniprotkb:RPA190(gene name)|psi-mi:RPA190(display_short)|uniprotkb:RPA1(gene name synonym)|uniprotkb:RRN1(gene name synonym)|uniprotkb:YOR341W(locus name)|uniprotkb:O6276(orf name)|uniprotkb:DNA-directed RNA polymerase I 190 kDa polypeptide(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 sgd:S000005868|refseq:NP_014986.3|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|ensemblfungi:YOR341W(gene)|ensemblfungi:YOR341W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0008270"(zinc ion binding)|dip:DIP-999N|mint:P10964 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:DF65A7AA459D5E6D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:krXuLY5fTE34McW4bnuPqns5Oy4559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P22138 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15736|uniprotkb:D6W421|ensemblfungi:YPR010C psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpa2_yeast(display_long)|uniprotkb:RPA135(gene name)|psi-mi:RPA135(display_short)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RRN2(gene name synonym)|uniprotkb:SRP3(gene name synonym)|uniprotkb:YPR010C(locus name)|uniprotkb:YP9531.03C(orf name)|uniprotkb:DNA-directed RNA polymerase I polypeptide 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_015335.1|sgd:S000006214|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5M5X|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YPR010C(gene)|ensemblfungi:YPR010C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|dip:DIP-135N|mint:P22138 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:72FA95B66F98C5F8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:9uVcBIikY0xLsnYo9ZZaqfLX2u8559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P47006 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-26109|uniprotkb:D6VW37|ensemblfungi:YJL148W psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpa34_yeast(display_long)|uniprotkb:YJL148W(locus name)|uniprotkb:J0637(orf name)|uniprotkb:RPA34(gene name)|psi-mi:RPA34(display_short)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_012387.1|sgd:S000003684|mint:P47006|dip:DIP-7973N|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YJL148W(gene)|ensemblfungi:YJL148W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:DCD42DFEC574EDB6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:KCG3Ws8+82TSLsqPB7bedHq/JEI559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P46669 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15745|uniprotkb:Q99187|uniprotkb:D6W335|ensemblfungi:YOR340C psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpa43_yeast(display_long)|uniprotkb:RPA43(gene name)|psi-mi:RPA43(display_short)|uniprotkb:RRN12(gene name synonym)|uniprotkb:YOR340C(locus name)|uniprotkb:O6271(orf name)|uniprotkb:DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_014985.1|sgd:S000005867|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|ensemblfungi:YOR340C(gene)|ensemblfungi:YOR340C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR036898|interpro:IPR041178|interpro:IPR041901|rcsb pdb:2RF4|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|dip:DIP-5405N|mint:P46669 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:0CC6421AC3BBC641 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:I8xMWRrEe0PhCstGStK44rQD30Q559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:Q01080 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15741|uniprotkb:D6W0U5|ensemblfungi:YNL248C psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpa49_yeast(display_long)|uniprotkb:RPA49(gene name)|psi-mi:RPA49(display_short)|uniprotkb:RRN13(gene name synonym)|uniprotkb:YNL248C(locus name)|uniprotkb:N0880(orf name)|uniprotkb:DNA-directed RNA polymerase I 49 kDa polypeptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_014151.1|sgd:S000005192|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772|go:"GO:0003677"(DNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0008361"(regulation of cell size)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|rcsb pdb:3NFH|rcsb pdb:3NFI|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|ensemblfungi:YNL248C(gene)|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|ensemblfungi:YNL248C_mRNA(transcript)|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|go:"GO:0001054"(RNA polymerase I activity)|rcsb pdb:6H67|rcsb pdb:6H68|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|rcsb pdb:6HKO|rcsb pdb:6RQH|dip:DIP-6577N|mint:Q01080 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:3D9BF05440D26021 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:B7Nabi651A5fAilRf/0F2GHps/U559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P20434 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:2A15F7114D69D829 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P20435 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15786|uniprotkb:D6W4I7|ensemblfungi:YPR187W psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpab2_yeast(display_long)|uniprotkb:RPO26(gene name)|psi-mi:RPO26(display_short)|uniprotkb:RPB6(gene name synonym)|uniprotkb:YPR187W(locus name)|uniprotkb:P9677.8(orf name)|uniprotkb:DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide(gene name synonym)|uniprotkb:ABC23(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_015513.1|sgd:S000006391|dip:DIP-2194N|mint:P20435|ensemblfungi:YPR187W(gene)|ensemblfungi:YPR187W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|interpro:IPR036161|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:AA3DEF529F94A5E4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:3kKsSGEw5OOi+Yp6budfnxfr8SQ559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P20436 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15794|ensemblfungi:YOR224C|uniprotkb:D6W2S9 psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpab3_yeast(display_long)|uniprotkb:RPB8(gene name)|psi-mi:RPB8(display_short)|uniprotkb:YOR224C(locus name)|uniprotkb:YOR50-14(orf name)|uniprotkb:DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide(gene name synonym)|uniprotkb:ABC14.5(gene name synonym)|uniprotkb:ABC14.4(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 ensemblfungi:YOR224C(gene)|ensemblfungi:YOR224C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:1A1D|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3FKI|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:1TWC|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3RZD|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|reactome:R-SCE-9018519|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:6HKO|rcsb pdb:7O4I|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:4Y7N|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|refseq:NP_014867.1|sgd:S000005750|dip:DIP-2195N|mint:P20436 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:5B71693FE6FD8863 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:N6EMzgz0bS1PktWm+ifkPaXu5ds559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P40422 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15850|uniprotkb:D3DL93|ensemblfungi:YHR143W-A psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpab4_yeast(display_long)|uniprotkb:RPC10(gene name)|psi-mi:RPC10(display_short)|uniprotkb:RPB12(gene name synonym)|uniprotkb:YHR143W-A(locus name)|uniprotkb:YHR143BW(orf name)|uniprotkb:ABC10-alpha(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 refseq:NP_012013.1|sgd:S000001185|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6EU3|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|rcsb pdb:6RWE|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3FKI|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3M4O|rcsb pdb:3GTK|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:3S14|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:3S15|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|ensemblfungi:YHR143W-A(gene)|ensemblfungi:YHR143W-A_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:2B63|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:2B8K|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5FYW|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5FZ5|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5W65|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNF|rcsb pdb:6CND|rcsb pdb:6CNC|rcsb pdb:6EU1|rcsb pdb:6EU0|rcsb pdb:6EU2|dip:DIP-936N|mint:P40422 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:066A3D982EC7361E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:5gONje6UC80U56+3GIMlGPiB+e8559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P22139 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15802|ensemblfungi:YOR210W|uniprotkb:D6W2R6 psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpab5_yeast(display_long)|uniprotkb:YOR210W(locus name)|uniprotkb:RPB10(gene name)|psi-mi:RPB10(display_short)|uniprotkb:ABC10-beta(gene name synonym)|uniprotkb:ABC8(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 sgd:S000005736|ensemblfungi:YOR210W(gene)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|ensemblfungi:YOR210W_mRNA(transcript)|interpro:IPR023580|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|go:"GO:0001054"(RNA polymerase I activity)|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0001172"(transcription, RNA-templated)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|go:"GO:0003677"(DNA binding)|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|go:"GO:0005654"(nucleoplasm)|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2NVQ|go:"GO:0005665"(RNA polymerase II, core complex)|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:2NVZ|go:"GO:0005666"(RNA polymerase III complex)|rcsb pdb:2R7Z|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:3GTO|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:7O4I|rcsb pdb:6HLS|rcsb pdb:7O4J|rcsb pdb:6I84|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|rcsb pdb:6O6C|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|reactome:R-SCE-73779|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|reactome:R-SCE-75953|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:3S1R|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5M3F|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|refseq:NP_014853.3|dip:DIP-825N|mint:P22139 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:E1F5733E8F466BE0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:cr2DgnGnKtGbd84HyGNM4xLS4FM559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P07703 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15831|ensemblfungi:YPR110C|uniprotkb:D6W4A9 psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpac1_yeast(display_long)|uniprotkb:RPC40(gene name)|psi-mi:RPC40(display_short)|uniprotkb:YPR110C(locus name)|uniprotkb:P8283.18(orf name)|uniprotkb:RPC5(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:C37(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 ensemblfungi:YPR110C(gene)|ensemblfungi:YPR110C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070893"(transposon integration)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|rcsb pdb:4C2M|rcsb pdb:4C3I|rcsb pdb:4C3H|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5G5L|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-76061|reactome:R-SCE-76066|refseq:NP_015435.1|sgd:S000006314|dip:DIP-17N|mint:P07703 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:76A5D6784403E990 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:erepZ6yX0AYInV5koxEj9V9E2pI559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32529 uniprotkb:P28000 intact:EBI-15756|uniprotkb:D6VWN4|ensemblfungi:YJR063W intact:EBI-15846|ensemblfungi:YNL113W|uniprotkb:D6W168 psi-mi:rpa12_yeast(display_long)|uniprotkb:RPA12(gene name)|psi-mi:RPA12(display_short)|uniprotkb:RRN4(gene name synonym)|uniprotkb:YJR063W(locus name)|uniprotkb:J1747(orf name)|uniprotkb:DNA-directed RNA polymerase I 13.7 kDa polypeptide(gene name synonym)|uniprotkb:A12(gene name synonym)|uniprotkb:A12.2(gene name synonym) psi-mi:rpac2_yeast(display_long)|uniprotkb:YNL113W(locus name)|uniprotkb:N1937(orf name)|uniprotkb:RPC19(gene name)|psi-mi:RPC19(display_short)|uniprotkb:DNA-directed RNA polymerases I and III 16 kDa polypeptide(gene name synonym)|uniprotkb:RPA19(gene name synonym)|uniprotkb:AC19(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Fernández-Tornero et al. (2013) pubmed:24153184|doi:"https://doi.org/10.1038/nature12636"|imex:IM-21949 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16079600|imex:IM-21949-1|dip:DIP-68864E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012597.1|sgd:S000003824|dip:DIP-236N|mint:P32529|ensemblfungi:YJR063W(gene)|ensemblfungi:YJR063W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|reactome:R-SCE-73762|reactome:R-SCE-73772 rcsb pdb:4C3H|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4YM7|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5G5L|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:5M5Y|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:4C2M|rcsb pdb:5W66|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6H67|rcsb pdb:6H68|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|ensemblfungi:YNL113W(gene)|ensemblfungi:YNL113W_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603|refseq:NP_014286.1|rcsb pdb:6TUT|sgd:S000005057|dip:DIP-130N|mint:P28000 psi-mi:"MI:0465"(dip) crc64:D79372070819987C crc64:0B048299A787EEDB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:B0Zmf643W8DtAQteaDk8PVvdqW4559292 rogid:5WE5tcol5BMb/TBn7MxNz1bVdGk559292 rigid:kQ0rldLyY6f+6tM+vGf3415DgWI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)