#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9VDE3 uniprotkb:O77430 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076504|imex:IM-22391-1|dip:DIP-196018E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rigid:Ugb/9ItdgJEbknZslfp6Fj6KzR0 false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VDE3 uniprotkb:Q24311 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312 psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076504|imex:IM-22391-1|dip:DIP-196018E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227 rigid:Ugb/9ItdgJEbknZslfp6Fj6KzR0 false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8INB9 uniprotkb:Q9VDE3 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16076524|imex:IM-22391-2|dip:DIP-196020E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rigid:YOfZoIzTkluE6xBDQQ0gBNzF/vk false flag tag:n-n myc tag:n-n|necessary binding region:196-510 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8INB9 uniprotkb:Q9VDE3 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16076547|imex:IM-22391-3|dip:DIP-196020E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rigid:YOfZoIzTkluE6xBDQQ0gBNzF/vk false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P68198 uniprotkb:Q8INB9 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16076566|imex:IM-22391-4|dip:DIP-196022E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 rigid:s5Yd8GPA61UNiflF5OV3A+LAvx8 false ha tag:0-0 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VDE3 uniprotkb:Q9W5E1 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 intact:EBI-153139|uniprotkb:O77429|ensemblmetazoa:FBpp0070117|ensemblmetazoa:FBpp0310165 psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:rbx1a_drome(display_long)|uniprotkb:Roc1a(gene name)|psi-mi:Roc1a(display_short)|uniprotkb:CG16982(orf name)|uniprotkb:Regulator of cullins 1a(gene name synonym)|uniprotkb:dRbx1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076587|imex:IM-22391-5|dip:DIP-196019E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N refseq:NP_001138143.2|ensemblmetazoa:FBgn0025638(gene)|ensemblmetazoa:FBtr0070122(transcript)|ensemblmetazoa:FBtr0343564(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|refseq:NP_569852.1|flybase:FBgn0025638|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016032"(viral process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045116"(protein neddylation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904801"(positive regulation of neuron remodeling)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|reactome:R-DME-110314|reactome:R-DME-1234176|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-4641258|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5632684|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400|reactome:R-DME-6781823|reactome:R-DME-6782135|reactome:R-DME-6782210|reactome:R-DME-68949|reactome:R-DME-8854050|reactome:R-DME-8932339|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|reactome:R-DME-983168|refseq:NP_001284754.1|dip:DIP-60717N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rogid:cdi4DGamYmT/5salxPwmZnusYVA7227 rigid:Qh09C6sI8BD/EVrADTV0bEMbvT8 false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VDE3 uniprotkb:O77430 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474 psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076587|imex:IM-22391-5|dip:DIP-196019E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227 rigid:Qh09C6sI8BD/EVrADTV0bEMbvT8 false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VDE3 uniprotkb:Q24311 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312 psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076587|imex:IM-22391-5|dip:DIP-196019E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227 rigid:Qh09C6sI8BD/EVrADTV0bEMbvT8 false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8INB9 uniprotkb:P68198 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 intact:EBI-86340|uniprotkb:Q0E8I1|uniprotkb:Q9VKW6|uniprotkb:Q9VQX7|uniprotkb:Q9VZL4|dip:DIP-32843N psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:ubiq_drome(display_long)|uniprotkb:RpL40(gene name)|psi-mi:RpL40(display_short)|uniprotkb:CG2960(orf name)|uniprotkb:RpS27A(gene name)|psi-mi:RpS27A(display_short)|uniprotkb:UBI-F80(gene name synonym)|uniprotkb:Ubi-f(gene name synonym)|uniprotkb:CG5271(orf name)|uniprotkb:Ubi-p63E(gene name)|psi-mi:Ubi-p63E(display_short)|uniprotkb:Ubi-m(gene name synonym)|uniprotkb:CG11624(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076610|imex:IM-22391-6|dip:DIP-196021E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N interpro:IPR000626(Ubiquitin)|flybase:FBgn0003941(RpL40)|flybase:FBgn0003943(Ubi-p63E)|go:"GO:0006911"(phagocytosis, engulfment)|refseq:NP_476776.1|refseq:NP_476778.1|refseq:NP_728908.1|go:"GO:0005515"(protein binding)|flybase:FBgn0003942(RpS27A)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|go:"GO:0009408"(response to heat)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:FBgn0003943|ensembl:FBgn0003941|ensembl:FBgn0003942|refseq:NP_523909.2|refseq:NP_995994.1|ensembl:FBgn0086558 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/15 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM7227 rigid:1tJSNDW8+B8XleIcZIIagKljjBU false myc tag:n-n ha tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8INB9 uniprotkb:Q9VDE3 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16076610|imex:IM-22391-6|dip:DIP-196021E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/15 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rigid:1tJSNDW8+B8XleIcZIIagKljjBU false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8INB9 uniprotkb:Q9VDE3 intact:EBI-162210|uniprotkb:Q0KI65|uniprotkb:Q24293|uniprotkb:Q24469|uniprotkb:Q24470|uniprotkb:Q7JN11|uniprotkb:Q8T9A5|uniprotkb:Q9VEY7|ensemblmetazoa:FBpp0082682 intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059 psi-mi:akt1_drome(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:CG4006(orf name)|uniprotkb:Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym) psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wong et al. (2013) pubmed:24068890|doi:10.1371/journal.pbio.1001657|imex:IM-22391 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16076634|imex:IM-22391-7|dip:DIP-196020E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_732113.3|refseq:NP_732114.1|refseq:NP_732115.1|flybase:FBgn0010379|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048477"(oogenesis)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0090278"(negative regulation of peptide hormone secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR039026|reactome:R-DME-110478|reactome:R-DME-110523|reactome:R-DME-1257604|reactome:R-DME-1358803|reactome:R-DME-1474151|reactome:R-DME-165158|reactome:R-DME-165159|reactome:R-DME-165181|reactome:R-DME-198323|reactome:R-DME-198693|reactome:R-DME-199418|reactome:R-DME-203615|reactome:R-DME-211163|reactome:R-DME-3769402|reactome:R-DME-389357|reactome:R-DME-389513|reactome:R-DME-392451|reactome:R-DME-450385|reactome:R-DME-450604|reactome:R-DME-5218920|reactome:R-DME-5628897|reactome:R-DME-6804759|reactome:R-DME-6811558|reactome:R-DME-69202|reactome:R-DME-69656|reactome:R-DME-8876198|reactome:R-DME-8948751|reactome:R-DME-9009391|reactome:R-DME-9604323|reactome:R-DME-9607240|reactome:R-DME-9614399|reactome:R-DME-9634638|ensemblmetazoa:FBgn0010379(gene)|ensemblmetazoa:FBtr0083228(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035206"(regulation of hemocyte proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|refseq:NP_001287353.1|refseq:NP_001287354.1|dip:DIP-49060N flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:O+TwU/5zv00wpwqXLxtrJrHk3lw7227 rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227 rigid:YOfZoIzTkluE6xBDQQ0gBNzF/vk false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)