#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P05067-PRO_0000000092	uniprotkb:P05067-PRO_0000000092	intact:EBI-821758	intact:EBI-821758	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416119|imex:IM-26151-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	intact:EBI-77613(chain-parent)	-	chain-seq-start:672|chain-seq-end:713	chain-seq-start:672|chain-seq-end:713	figure legend:1A-1|comment:Beta-amyloid peptide consists primarily of high-n oligomers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/11/09	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:cKD4D1MnREsSp9G3FMjXsPLwG4g	false	biotin tag:n-n	biotin tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P05067-PRO_0000000092	intact:EBI-821758	intact:EBI-821758	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0982"(electrophoretic mobility-based method)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416167|imex:IM-26151-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	intact:EBI-77613(chain-parent)	-	chain-seq-start:672|chain-seq-end:713	chain-seq-start:672|chain-seq-end:713	figure legend:1B, S1B|comment:Beta-amyloid peptide consists primarily of high-n oligomers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/11/09	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:cKD4D1MnREsSp9G3FMjXsPLwG4g	false	biotin tag:n-n	biotin tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416187|imex:IM-26151-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:1 C/D|comment:Relative to monomeric Amyloid-beta42, oligomerized  peptides bound to PirB-expressing cells about 6 times as much.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:180.0x10^-9(molar)	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	green fluorescent protein tag:?-?	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416187|imex:IM-26151-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:1 C/D|comment:Relative to monomeric Amyloid-beta42, oligomerized  peptides bound to PirB-expressing cells about 6 times as much.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:180.0x10^-9(molar)	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	green fluorescent protein tag:?-?	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q8N423	uniprotkb:P05067-PRO_0000000092	intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373	intact:EBI-821758	psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416108|imex:IM-26151-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:2 G/H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:88T9yRZZ4UZGpJBZ7ts6cuxS7bk	false	sufficient binding region:24-223(IPR007110)|fc-igg tag:c-c	sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N423	uniprotkb:P05067-PRO_0000000092	intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373	intact:EBI-821758	psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416108|imex:IM-26151-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:2 G/H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:88T9yRZZ4UZGpJBZ7ts6cuxS7bk	false	sufficient binding region:24-223(IPR007110)|fc-igg tag:c-c	sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416365|imex:IM-26151-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:2 G/H, Supp 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	sufficient binding region:22-224(IPR007110)|fc-igg tag:c-c	sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416365|imex:IM-26151-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:2 G/H, Supp 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	sufficient binding region:22-224(IPR007110)|fc-igg tag:c-c	sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P35235	uniprotkb:P97484	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	intact:EBI-15728641|ensembl:ENSMUSP00000077546	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416415|imex:IM-26151-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	-	-	-	figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-forebrain)|taxid:10090(Mus musculus, forebrain)	-	2017/06/28	2020/01/07	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rigid:AUpKBae2jLc+BT2t5E6X2cGsYo8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416500|imex:IM-26151-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Supp Fig 1B|comment:PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	-	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416500|imex:IM-26151-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Supp Fig 1B|comment:PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	-	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:Q9JK11	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-919972|uniprotkb:Q9JK10|uniprotkb:Q9R0D9|uniprotkb:Q9WUE9|uniprotkb:Q9WUF0	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:rtn4_rat(display_long)|uniprotkb:Rtn4(gene name)|psi-mi:Rtn4(display_short)|uniprotkb:Nogo(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Glut4 vesicle 20 kDa protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416578|imex:IM-26151-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	rgd:620989|refseq:NP_114019.1|refseq:XP_006251671.1|refseq:XP_006251670.2|mint:Q9JK11|refseq:XP_017454882.1|dip:DIP-37179N|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007568"(aging)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|reactome:R-RNO-193634	-	-	-	figure legend:Supp Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:CEWzvhKyKl/Cdz7MmociJDKwNPk10116	rigid:kwehGsceJx5XFcPV7YFW2RyFPNw	false	-	sufficient binding region:1026-1090|fc-igg tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P97484	intact:EBI-821758	intact:EBI-15728641|ensembl:ENSMUSP00000077546	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416664|imex:IM-26151-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	-	chain-seq-start:672|chain-seq-end:713	-	figure legend:Supp Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	biotin tag:n-n|sufficient binding region:1-42	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P05067-PRO_0000000092	intact:EBI-821758	intact:EBI-821758	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416664|imex:IM-26151-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	intact:EBI-77613(chain-parent)	-	chain-seq-start:672|chain-seq-end:713	chain-seq-start:672|chain-seq-end:713	figure legend:Supp Fig 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	biotin tag:n-n|sufficient binding region:1-42	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:A2NTK1	intact:EBI-821758	intact:EBI-16416693	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:a2ntk1_mouse(display_long)|uniprotkb:Pira4(gene name)|psi-mi:Pira4(display_short)|uniprotkb:6M7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416680|imex:IM-26151-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	refseq:NP_035221.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013151(Immunoglobulin)|interpro:IPR036179	-	chain-seq-start:672|chain-seq-end:713	-	figure legend:Supp Fig 3D-2|comment:weak binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:eB2IlQqRG3Pn/7tgkojfyQ/HaW410090	rigid:DsaHhjpbABxdx14d6IlGXkmhrsQ	false	biotin tag:n-n|sufficient binding region:1-42	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P05067-PRO_0000000092	intact:EBI-821758	intact:EBI-821758	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416680|imex:IM-26151-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	intact:EBI-77613(chain-parent)	-	chain-seq-start:672|chain-seq-end:713	chain-seq-start:672|chain-seq-end:713	figure legend:Supp Fig 3D-2|comment:weak binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:DsaHhjpbABxdx14d6IlGXkmhrsQ	false	biotin tag:n-n|sufficient binding region:1-42	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416232|imex:IM-26151-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:1 E|comment:Oligomerised Amyloid-beta42 peptides were used.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	-	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416232|imex:IM-26151-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:1 E|comment:Oligomerised Amyloid-beta42 peptides were used.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	-	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q8N423	uniprotkb:P05067-PRO_0000000092	intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373	intact:EBI-821758	psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416705|imex:IM-26151-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Supp 5|comment:Oligomerised Amyloid-beta42 peptides were used.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:88T9yRZZ4UZGpJBZ7ts6cuxS7bk	false	myc tag:c-c|flag tag:c-c	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q8N423	uniprotkb:P05067-PRO_0000000092	intact:EBI-2816428|uniprotkb:Q8NHJ7|uniprotkb:Q8NHJ8|uniprotkb:O75017|uniprotkb:A8MU67|uniprotkb:C9JF29|ensembl:ENSP00000319960|ensembl:ENSP00000375626|ensembl:ENSP00000375628|ensembl:ENSP00000375629|ensembl:ENSP00000410117|ensembl:ENSP00000480302|ensembl:ENSP00000481208|ensembl:ENSP00000482933|ensembl:ENSP00000483553|ensembl:ENSP00000484373	intact:EBI-821758	psi-mi:lirb2_human(display_long)|uniprotkb:LILRB2(gene name)|psi-mi:LILRB2(display_short)|uniprotkb:ILT4(gene name synonym)|uniprotkb:LIR2(gene name synonym)|uniprotkb:MIR10(gene name synonym)|uniprotkb:CD85 antigen-like family member D(gene name synonym)|uniprotkb:Immunoglobulin-like transcript 4(gene name synonym)|uniprotkb:Monocyte/macrophage immunoglobulin-like receptor 10(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416705|imex:IM-26151-31	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-59888N|ensembl:ENSG00000131042(gene)|ensembl:ENSG00000274513(gene)|ensembl:ENSG00000275463(gene)|ensembl:ENSG00000276146(gene)|ensembl:ENST00000314446(transcript)|ensembl:ENST00000391746(transcript)|ensembl:ENST00000391748(transcript)|ensembl:ENST00000391749(transcript)|ensembl:ENST00000434421(transcript)|ensembl:ENST00000610886(transcript)|ensembl:ENST00000617341(transcript)|ensembl:ENST00000617886(transcript)|ensembl:ENST00000618392(transcript)|ensembl:ENST00000618705(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002578"(negative regulation of antigen processing and presentation)|go:"GO:0002645"(positive regulation of tolerance induction)|go:"GO:0002666"(positive regulation of T cell tolerance induction)|go:"GO:0002767"(immune response-inhibiting cell surface receptor signaling pathway)|go:"GO:0002774"(Fc receptor mediated inhibitory signaling pathway)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007611"(learning or memory)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0023025"(MHC class Ib protein complex binding)|go:"GO:0023029"(MHC class Ib protein binding)|go:"GO:0032396"(inhibitory MHC class I receptor activity)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045591"(positive regulation of regulatory T cell differentiation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140105"(interleukin-10-mediated signaling pathway)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:2000524"(negative regulation of T cell costimulation)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2DYP|rcsb pdb:2GW5|rcsb pdb:4LLA|rcsb pdb:6AED|rcsb pdb:6BCS|reactome:R-HSA-198933|reactome:R-HSA-6798695	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Supp 5|comment:Oligomerised Amyloid-beta42 peptides were used.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:nFaZ5NEqw5u/3Du7Mi6fJpEQEdo9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:88T9yRZZ4UZGpJBZ7ts6cuxS7bk	false	myc tag:c-c|flag tag:c-c	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P97484	uniprotkb:P05067-PRO_0000000092	intact:EBI-15728641|ensembl:ENSMUSP00000077546	intact:EBI-821758	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416536|imex:IM-26151-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	intact:EBI-77613(chain-parent)	-	-	chain-seq-start:672|chain-seq-end:713	figure legend:Supp Fig 1Ci|comment:PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/14	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	-	biotin tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P97484	intact:EBI-821758	intact:EBI-15728641|ensembl:ENSMUSP00000077546	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416734|imex:IM-26151-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	-	chain-seq-start:672|chain-seq-end:713	-	figure legend:Supp fig 6A|comment:PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42.|comment:Amyloid-beta 1-42 oligomers appear to bind preferentially to dimeric PirB, as seen under partially-reducing conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	biotin tag:n-n|sufficient binding region:1-42	-	-	2	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P05067-PRO_0000000092	intact:EBI-821758	intact:EBI-821758	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416734|imex:IM-26151-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	intact:EBI-77613(chain-parent)	-	chain-seq-start:672|chain-seq-end:713	chain-seq-start:672|chain-seq-end:713	figure legend:Supp fig 6A|comment:PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42.|comment:Amyloid-beta 1-42 oligomers appear to bind preferentially to dimeric PirB, as seen under partially-reducing conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	biotin tag:n-n|sufficient binding region:1-42	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P97484	intact:EBI-821758	intact:EBI-15728641|ensembl:ENSMUSP00000077546	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:lirb3_mouse(display_long)|uniprotkb:Lilrb3(gene name)|psi-mi:Lilrb3(display_short)|uniprotkb:Pirb(gene name synonym)|uniprotkb:Cell-surface glycoprotein p91(gene name synonym)|uniprotkb:Paired immunoglobulin-like receptor B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416750|imex:IM-26151-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	ensembl:ENSMUSG00000058818(gene)|ensembl:ENSMUST00000078451(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_035225.2|dip:DIP-59889N	-	chain-seq-start:672|chain-seq-end:713	-	figure legend:Supp Fig 1C, Supp fig 6Ai|comment:PirB  interacts preferentially with oligomeric forms of Amyloid-beta 1-42.|comment:This interaction is seen under fully reducing conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:LvDmslSnZmh1nZvksx5uODaSLd010090	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	biotin tag:n-n|sufficient binding region:1-42	-	-	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P05067-PRO_0000000092	uniprotkb:P05067-PRO_0000000092	intact:EBI-821758	intact:EBI-821758	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:p05067-pro_0000000092(display_long)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Kim et al. (2013)	pubmed:24052308|imex:IM-26151	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16416750|imex:IM-26151-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-77613(chain-parent)	intact:EBI-77613(chain-parent)	-	chain-seq-start:672|chain-seq-end:713	chain-seq-start:672|chain-seq-end:713	figure legend:Supp Fig 1C, Supp fig 6Ai|comment:PirB  interacts preferentially with oligomeric forms of Amyloid-beta 1-42.|comment:This interaction is seen under fully reducing conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/28	2017/09/15	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rogid:EBSGluIZCNVA1aC0Wdg7MlDdGxk9606	rigid:PdWYGdcuJebuVEUlmoz07kDyYHQ	false	biotin tag:n-n|sufficient binding region:1-42	biotin tag:n-n|sufficient binding region:1-42	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)