#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P60896	uniprotkb:P51587	intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jeyasekharan et al. (2013)	pubmed:24013206|doi:10.1038/nsmb.2666|imex:IM-21882	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16072988|imex:IM-21882-1|dip:DIP-60509E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:PWXTveLxuio5va1OslxM8lWAEK49606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rigid:0j6yw17EItt18+FG/WjclN+t1b4	false	mcherry fluorescent protein tag:n-n	sufficient binding region:2461-2975|mutation disrupting interaction strength:2723-2723|mutation decreasing interaction strength:2725-2725|yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14980	uniprotkb:P51587	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jeyasekharan et al. (2013)	pubmed:24013206|doi:10.1038/nsmb.2666|imex:IM-21882	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16073038|imex:IM-21882-3|dip:DIP-192416E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rigid:P3BbNjKRsVZbDBCRAgMoJ02oTz4	false	his tag:n-n	glutathione s tranferase tag:n-n|sufficient binding region:2461-2975	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06609	uniprotkb:O14980	intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8	intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848	psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym)	psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Jeyasekharan et al. (2013)	pubmed:24013206|doi:10.1038/nsmb.2666|imex:IM-21882	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16073017|imex:IM-21882-2|dip:DIP-192417E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N	ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606	rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606	rigid:MNjakm+BDyQrtNxDWKlrXzdVIb0	false	glutathione s tranferase tag:n-n	his tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P60896	uniprotkb:P51587	intact:EBI-79819|ensembl:ENSP00000248566|uniprotkb:Q13437|uniprotkb:Q61067	intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879	psi-mi:sem1_human(display_long)|uniprotkb:C7orf76(gene name synonym)|uniprotkb:SEM1(gene name)|psi-mi:SEM1(display_short)|uniprotkb:26S proteasome complex subunit DSS1(gene name synonym)|uniprotkb:DSS1(gene name synonym)|uniprotkb:Deleted in split hand/split foot protein 1(gene name synonym)|uniprotkb:SHFDG1(gene name synonym)|uniprotkb:SHFM1(gene name synonym)|uniprotkb:Split hand/foot deleted protein 1(gene name synonym)|uniprotkb:Split hand/foot malformation type 1 protein(gene name synonym)	psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Jeyasekharan et al. (2013)	pubmed:24013206|doi:10.1038/nsmb.2666|imex:IM-21882	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-16073061|imex:IM-21882-4|dip:DIP-60509E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000127922(gene)|ensembl:ENST00000248566(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043248"(proteasome assembly)|interpro:IPR007834(DSS1/SEM1)|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:1IYJ|rcsb pdb:1MIU|rcsb pdb:1MJE|rcsb pdb:3T5X|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:5M32|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|rcsb pdb:5T0C|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:5T0G|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|rcsb pdb:5T0H|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VGZ|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_006295.1|dip:DIP-31023N	ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:PWXTveLxuio5va1OslxM8lWAEK49606	rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606	rigid:0j6yw17EItt18+FG/WjclN+t1b4	false	mcherry fluorescent protein tag:n-n	sufficient binding region:2461-2975|mutation disrupting interaction strength:2723-2723|mutation disrupting interaction strength:2725-2725|yellow fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)