#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6NPA6 uniprotkb:Q8T0S6 intact:EBI-3415099|ensemblmetazoa:FBpp0099804 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:q6npa6_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG30132(gene name synonym)|uniprotkb:27C1(gene name synonym)|uniprotkb:"BcDNA:RH48823"(gene name synonym)|uniprotkb:CG11960(gene name synonym)|uniprotkb:CG16701(gene name synonym)|uniprotkb:CG30131(gene name synonym)|uniprotkb:DPAR-1(gene name synonym)|uniprotkb:DPar1(gene name synonym)|uniprotkb:Dmel\CG8201(gene name synonym)|uniprotkb:EMK(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:PAR-1(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:Par-1(gene name synonym)|uniprotkb:Par1(gene name synonym)|uniprotkb:anon-WO0210402.19(gene name synonym)|uniprotkb:dMARK(gene name synonym)|uniprotkb:dPAR-1(gene name synonym)|uniprotkb:dPAR1(gene name synonym)|uniprotkb:dPar-1(gene name synonym)|uniprotkb:dPar1(gene name synonym)|uniprotkb:"l(2)27C1"(gene name synonym)|uniprotkb:"l(2)k06323"(gene name synonym)|uniprotkb:par1(gene name synonym)|uniprotkb:CG8201(orf name)|uniprotkb:Dmel_CG8201(orf name) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2012) pubmed:23940457|doi:10.1371/journal.pbio.1001620|imex:IM-21563 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16068905|imex:IM-21563-1|dip:DIP-191960E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014542.1|flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100390(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|dip:DIP-60481N interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:11xnYqRl6bihTNZTQzpE4JvpyY47227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:yZKeSlBjFmCPOVSXR9rzSpYWrOU false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VCR6 uniprotkb:Q6NPA6 intact:EBI-145004|uniprotkb:Q8MQH6|uniprotkb:Q8T9A6|uniprotkb:Q9VCR5|ensemblmetazoa:FBpp0083749 intact:EBI-3415099|ensemblmetazoa:FBpp0099804 psi-mi:sav_drome(display_long)|uniprotkb:sav(gene name)|psi-mi:sav(display_short)|uniprotkb:SHRP(gene name synonym)|uniprotkb:CG33193(orf name)|uniprotkb:Shar-pei(gene name synonym) psi-mi:q6npa6_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG30132(gene name synonym)|uniprotkb:27C1(gene name synonym)|uniprotkb:"BcDNA:RH48823"(gene name synonym)|uniprotkb:CG11960(gene name synonym)|uniprotkb:CG16701(gene name synonym)|uniprotkb:CG30131(gene name synonym)|uniprotkb:DPAR-1(gene name synonym)|uniprotkb:DPar1(gene name synonym)|uniprotkb:Dmel\CG8201(gene name synonym)|uniprotkb:EMK(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:PAR-1(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:Par-1(gene name synonym)|uniprotkb:Par1(gene name synonym)|uniprotkb:anon-WO0210402.19(gene name synonym)|uniprotkb:dMARK(gene name synonym)|uniprotkb:dPAR-1(gene name synonym)|uniprotkb:dPAR1(gene name synonym)|uniprotkb:dPar-1(gene name synonym)|uniprotkb:dPar1(gene name synonym)|uniprotkb:"l(2)27C1"(gene name synonym)|uniprotkb:"l(2)k06323"(gene name synonym)|uniprotkb:par1(gene name synonym)|uniprotkb:CG8201(orf name)|uniprotkb:Dmel_CG8201(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2012) pubmed:23940457|doi:10.1371/journal.pbio.1001620|imex:IM-21563 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16068949|imex:IM-21563-3|dip:DIP-191961E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788721.1|flybase:FBgn0053193|dip:DIP-18696N|ensemblmetazoa:FBgn0053193(gene)|ensemblmetazoa:FBtr0084356(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0035329"(hippo signaling)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0106037"(apicomedial cortex)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150 refseq:NP_001014542.1|flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100390(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|dip:DIP-60481N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:/omCdWbZCQT01Iwj5eU7isz1Kr47227 rogid:11xnYqRl6bihTNZTQzpE4JvpyY47227 rigid:hKDFJiDSgUxORY8H0qd08acdSvU false myc tag:n-n ha tag:n-n|sufficient binding region:1-562 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6NPA6 uniprotkb:Q8T0S6 intact:EBI-3415099|ensemblmetazoa:FBpp0099804 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:q6npa6_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG30132(gene name synonym)|uniprotkb:27C1(gene name synonym)|uniprotkb:"BcDNA:RH48823"(gene name synonym)|uniprotkb:CG11960(gene name synonym)|uniprotkb:CG16701(gene name synonym)|uniprotkb:CG30131(gene name synonym)|uniprotkb:DPAR-1(gene name synonym)|uniprotkb:DPar1(gene name synonym)|uniprotkb:Dmel\CG8201(gene name synonym)|uniprotkb:EMK(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:PAR-1(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:Par-1(gene name synonym)|uniprotkb:Par1(gene name synonym)|uniprotkb:anon-WO0210402.19(gene name synonym)|uniprotkb:dMARK(gene name synonym)|uniprotkb:dPAR-1(gene name synonym)|uniprotkb:dPAR1(gene name synonym)|uniprotkb:dPar-1(gene name synonym)|uniprotkb:dPar1(gene name synonym)|uniprotkb:"l(2)27C1"(gene name synonym)|uniprotkb:"l(2)k06323"(gene name synonym)|uniprotkb:par1(gene name synonym)|uniprotkb:CG8201(orf name)|uniprotkb:Dmel_CG8201(orf name) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2012) pubmed:23940457|doi:10.1371/journal.pbio.1001620|imex:IM-21563 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16068972|imex:IM-21563-4|dip:DIP-191960E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014542.1|flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100390(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|dip:DIP-60481N interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:11xnYqRl6bihTNZTQzpE4JvpyY47227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:yZKeSlBjFmCPOVSXR9rzSpYWrOU false ha tag:n-n|sufficient binding region:1-562|sufficient binding region:563-833 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VCR6 uniprotkb:Q8T0S6 intact:EBI-145004|uniprotkb:Q8MQH6|uniprotkb:Q8T9A6|uniprotkb:Q9VCR5|ensemblmetazoa:FBpp0083749 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:sav_drome(display_long)|uniprotkb:sav(gene name)|psi-mi:sav(display_short)|uniprotkb:SHRP(gene name synonym)|uniprotkb:CG33193(orf name)|uniprotkb:Shar-pei(gene name synonym) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2012) pubmed:23940457|doi:10.1371/journal.pbio.1001620|imex:IM-21563 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16068997|imex:IM-21563-5|dip:DIP-22178E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788721.1|flybase:FBgn0053193|dip:DIP-18696N|ensemblmetazoa:FBgn0053193(gene)|ensemblmetazoa:FBtr0084356(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0035329"(hippo signaling)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0106037"(apicomedial cortex)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150 interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:/omCdWbZCQT01Iwj5eU7isz1Kr47227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:IY/eIY0l+upAb7fqCoqMGKrc9KU false myc tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6NPA6 uniprotkb:Q8T0S6 intact:EBI-3415099|ensemblmetazoa:FBpp0099804 intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253 psi-mi:q6npa6_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG30132(gene name synonym)|uniprotkb:27C1(gene name synonym)|uniprotkb:"BcDNA:RH48823"(gene name synonym)|uniprotkb:CG11960(gene name synonym)|uniprotkb:CG16701(gene name synonym)|uniprotkb:CG30131(gene name synonym)|uniprotkb:DPAR-1(gene name synonym)|uniprotkb:DPar1(gene name synonym)|uniprotkb:Dmel\CG8201(gene name synonym)|uniprotkb:EMK(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:PAR-1(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:Par-1(gene name synonym)|uniprotkb:Par1(gene name synonym)|uniprotkb:anon-WO0210402.19(gene name synonym)|uniprotkb:dMARK(gene name synonym)|uniprotkb:dPAR-1(gene name synonym)|uniprotkb:dPAR1(gene name synonym)|uniprotkb:dPar-1(gene name synonym)|uniprotkb:dPar1(gene name synonym)|uniprotkb:"l(2)27C1"(gene name synonym)|uniprotkb:"l(2)k06323"(gene name synonym)|uniprotkb:par1(gene name synonym)|uniprotkb:CG8201(orf name)|uniprotkb:Dmel_CG8201(orf name) psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2012) pubmed:23940457|doi:10.1371/journal.pbio.1001620|imex:IM-21563 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16068926|imex:IM-21563-2|dip:DIP-191960E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014542.1|flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100390(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|dip:DIP-60481N interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:11xnYqRl6bihTNZTQzpE4JvpyY47227 rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227 rigid:yZKeSlBjFmCPOVSXR9rzSpYWrOU false ha tag:n-n|sufficient binding region:1-562 myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9VCR6 uniprotkb:Q6NPA6 intact:EBI-145004|uniprotkb:Q8MQH6|uniprotkb:Q8T9A6|uniprotkb:Q9VCR5|ensemblmetazoa:FBpp0083749 intact:EBI-3415099|ensemblmetazoa:FBpp0099804 psi-mi:sav_drome(display_long)|uniprotkb:sav(gene name)|psi-mi:sav(display_short)|uniprotkb:SHRP(gene name synonym)|uniprotkb:CG33193(orf name)|uniprotkb:Shar-pei(gene name synonym) psi-mi:q6npa6_drome(display_long)|uniprotkb:par-1(gene name)|psi-mi:par-1(display_short)|uniprotkb:CG30132(gene name synonym)|uniprotkb:27C1(gene name synonym)|uniprotkb:"BcDNA:RH48823"(gene name synonym)|uniprotkb:CG11960(gene name synonym)|uniprotkb:CG16701(gene name synonym)|uniprotkb:CG30131(gene name synonym)|uniprotkb:DPAR-1(gene name synonym)|uniprotkb:DPar1(gene name synonym)|uniprotkb:Dmel\CG8201(gene name synonym)|uniprotkb:EMK(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:PAR-1(gene name synonym)|uniprotkb:PAR1(gene name synonym)|uniprotkb:Par-1(gene name synonym)|uniprotkb:Par1(gene name synonym)|uniprotkb:anon-WO0210402.19(gene name synonym)|uniprotkb:dMARK(gene name synonym)|uniprotkb:dPAR-1(gene name synonym)|uniprotkb:dPAR1(gene name synonym)|uniprotkb:dPar-1(gene name synonym)|uniprotkb:dPar1(gene name synonym)|uniprotkb:"l(2)27C1"(gene name synonym)|uniprotkb:"l(2)k06323"(gene name synonym)|uniprotkb:par1(gene name synonym)|uniprotkb:CG8201(orf name)|uniprotkb:Dmel_CG8201(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2012) pubmed:23940457|doi:10.1371/journal.pbio.1001620|imex:IM-21563 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16069016|imex:IM-21563-6|dip:DIP-191961E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_788721.1|flybase:FBgn0053193|dip:DIP-18696N|ensemblmetazoa:FBgn0053193(gene)|ensemblmetazoa:FBtr0084356(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007444"(imaginal disc development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0035329"(hippo signaling)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045570"(regulation of imaginal disc growth)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072002"(Malpighian tubule development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0106037"(apicomedial cortex)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150 refseq:NP_001014542.1|flybase:FBgn0260934|ensemblmetazoa:FBgn0260934(gene)|ensemblmetazoa:FBtr0100390(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001737"(establishment of imaginal disc-derived wing hair orientation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007318"(pole plasm protein localization)|go:"GO:0009798"(axis specification)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016325"(oocyte microtubule cytoskeleton organization)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030709"(border follicle cell delamination)|go:"GO:0030860"(regulation of polarized epithelial cell differentiation)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045169"(fusome)|go:"GO:0045172"(germline ring canal)|go:"GO:0045451"(pole plasm oskar mRNA localization)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0061174"(type I terminal bouton)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|dip:DIP-60481N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:/omCdWbZCQT01Iwj5eU7isz1Kr47227 rogid:11xnYqRl6bihTNZTQzpE4JvpyY47227 rigid:hKDFJiDSgUxORY8H0qd08acdSvU false myc tag:n-n ha tag:n-n|sufficient binding region:1-562 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)