#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q4KMI8 uniprotkb:Q4KMI8 intact:EBI-16066720 intact:EBI-16066720 psi-mi:q4kmi8_danre(display_long)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)|uniprotkb:Polo-like kinase(gene name synonym) psi-mi:q4kmi8_danre(display_long)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)|uniprotkb:Polo-like kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Xu et al. (2013) pubmed:23893132|doi:10.1038/nsmb.2623|imex:IM-21872 taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:1127"(putative self interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16066747|imex:IM-21872-1|dip:DIP-192399E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3D5X|rcsb pdb:3DB6|rcsb pdb:3DB8|rcsb pdb:3DBC|rcsb pdb:3DBD|rcsb pdb:3DBE|rcsb pdb:3DBF|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|rcsb pdb:3D5W|refseq:NP_001003890.3|dip:DIP-60544N rcsb pdb:3D5X|rcsb pdb:3DB6|rcsb pdb:3DB8|rcsb pdb:3DBC|rcsb pdb:3DBD|rcsb pdb:3DBE|rcsb pdb:3DBF|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|rcsb pdb:3D5W|refseq:NP_001003890.3|dip:DIP-60544N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:Ka4A2dlB09b7Do85fIwA5thtgYM7955 rogid:Ka4A2dlB09b7Do85fIwA5thtgYM7955 rigid:e/YOvMwb1P5Xdj9o4gB+rj3yaFI false sufficient binding region:359-595|glutathione s tranferase tag:n-n sufficient binding region:17-312|his tag:n-n|mutation disrupting interaction strength:123-123|mutation disrupting interaction strength:130-130|mutation disrupting interaction strength:306-306|mutation disrupting interaction strength:307-307 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P23226 uniprotkb:Q4KMI8 intact:EBI-239813|uniprotkb:Q53YG1|uniprotkb:Q9V9S1|intact:EBI-3432748 intact:EBI-16066720 psi-mi:ma205_drome(display_long)|uniprotkb:Map205(gene name)|psi-mi:Map205(display_short)|uniprotkb:CG1483(orf name) psi-mi:q4kmi8_danre(display_long)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)|uniprotkb:Polo-like kinase(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Xu et al. (2013) pubmed:23893132|doi:10.1038/nsmb.2623|imex:IM-21872 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16066784|imex:IM-21872-2|dip:DIP-192398E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524615.1|flybase:FBgn0002645|dip:DIP-60545N|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030496"(midbody)|rcsb pdb:4J7B rcsb pdb:3D5X|rcsb pdb:3DB6|rcsb pdb:3DB8|rcsb pdb:3DBC|rcsb pdb:3DBD|rcsb pdb:3DBE|rcsb pdb:3DBF|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|rcsb pdb:3D5W|refseq:NP_001003890.3|dip:DIP-60544N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:Sob57Ow+AsFDQ74qdtBz4j4V0jA7227 rogid:Ka4A2dlB09b7Do85fIwA5thtgYM7955 rigid:H/ZkRec9MGSBkq3Qsj/fjUty1xU false sufficient binding region:276-325 sufficient binding region:360-595,17-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23226 uniprotkb:Q4KMI8 intact:EBI-239813|uniprotkb:Q53YG1|uniprotkb:Q9V9S1|intact:EBI-3432748 intact:EBI-16066720 psi-mi:ma205_drome(display_long)|uniprotkb:Map205(gene name)|psi-mi:Map205(display_short)|uniprotkb:CG1483(orf name) psi-mi:q4kmi8_danre(display_long)|uniprotkb:plk1(gene name)|psi-mi:plk1(display_short)|uniprotkb:Polo-like kinase(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Xu et al. (2013) pubmed:23893132|doi:10.1038/nsmb.2623|imex:IM-21872 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16066807|imex:IM-21872-3|dip:DIP-192398E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524615.1|flybase:FBgn0002645|dip:DIP-60545N|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030496"(midbody)|rcsb pdb:4J7B rcsb pdb:3D5X|rcsb pdb:3DB6|rcsb pdb:3DB8|rcsb pdb:3DBC|rcsb pdb:3DBD|rcsb pdb:3DBE|rcsb pdb:3DBF|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|rcsb pdb:3D5W|refseq:NP_001003890.3|dip:DIP-60544N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:Sob57Ow+AsFDQ74qdtBz4j4V0jA7227 rogid:Ka4A2dlB09b7Do85fIwA5thtgYM7955 rigid:H/ZkRec9MGSBkq3Qsj/fjUty1xU false sufficient binding region:276-325 sufficient binding region:360-595,17-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)