#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53127 uniprotkb:P0CX50 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-7433456|uniprotkb:P07279|intact:MINT-8285574|uniprotkb:D6W0P3|ensemblfungi:YNL301C|ensemblfungi:YOL120C psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rl18b_yeast(display_long)|uniprotkb:RPL18B(gene name)|psi-mi:RPL18B(display_short)|uniprotkb:RP28(gene name synonym)|uniprotkb:RP28B(gene name synonym)|uniprotkb:N0425(orf name)|uniprotkb:YNL301C(locus name)|uniprotkb:Large ribosomal subunit protein eL18-B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 reactome:R-SCE-156827|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|rcsb pdb:4V8T|interpro:IPR000039(Ribosomal protein L18e)|refseq:NP_014521.1|interpro:IPR021131|sgd:S000005245|refseq:NP_014098.1|interpro:IPR021132|ensemblfungi:YNL301C(gene)|ensemblfungi:YNL301C_mRNA(transcript)|ensemblfungi:YOL120C(gene)|ensemblfungi:YOL120C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR036227|reactome:R-SCE-1799339 - crc64:758D3FB130DF2357 comment:mint figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:86FYqzXCj53J/AFzhS7OtvmGwWs559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:P0CX38 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-7432889|intact:MINT-8285672|uniprotkb:P05751|uniprotkb:Q02894|uniprotkb:D6VQH5|uniprotkb:P02365|ensemblfungi:YBR181C|ensemblfungi:YPL090C psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rs6b_yeast(display_long)|uniprotkb:RPS6B(gene name)|psi-mi:RPS6B(display_short)|uniprotkb:RP9(gene name synonym)|uniprotkb:RPS102(gene name synonym)|uniprotkb:YS4(gene name synonym)|uniprotkb:YBR1244(orf name)|uniprotkb:YBR181C(locus name)|uniprotkb:RPS10A(gene name synonym)|uniprotkb:S10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6-B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-6791226|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|refseq:NP_015235.1|interpro:IPR001377(Ribosomal protein S6e)|sgd:S000000385|refseq:NP_009740.3|ensemblfungi:YBR181C(gene)|ensemblfungi:YBR181C_mRNA(transcript)|ensemblfungi:YPL090C(gene)|ensemblfungi:YPL090C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032040"(small-subunit processome)|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-SCE-72649|reactome:R-SCE-1799339 - crc64:758D3FB130DF2357 comment:mint figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:EeJ5VG5FWn5tAtQo5cEsiAM6K7k559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:P0CX83 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-7433003|uniprotkb:D6VPX3|intact:MINT-8285577|uniprotkb:P05735|ensemblfungi:YBL027W|ensemblfungi:YBR084C-A psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rl19b_yeast(display_long)|uniprotkb:RPL19B(gene name)|psi-mi:RPL19B(display_short)|uniprotkb:L23(gene name synonym)|uniprotkb:RP15L(gene name synonym)|uniprotkb:RP33(gene name synonym)|uniprotkb:RPL23B(gene name synonym)|uniprotkb:YL14(gene name synonym)|uniprotkb:YL14B(gene name synonym)|uniprotkb:YBL0424(orf name)|uniprotkb:YBL027W(locus name)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 reactome:R-SCE-156827|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|rcsb pdb:4V8Y|rcsb pdb:4V8Z|refseq:NP_009641.1|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|refseq:NP_009526.1|interpro:IPR000196(Ribosomal protein L19/L19e)|sgd:S000000123|interpro:IPR023638|interpro:IPR033935|ensemblfungi:YBL027W(gene)|ensemblfungi:YBL027W_mRNA(transcript)|ensemblfungi:YBR084C-A(gene)|ensemblfungi:YBR084C-A_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|rcsb pdb:4V8T|interpro:IPR035970|interpro:IPR039547|reactome:R-SCE-1799339 - crc64:758D3FB130DF2357 comment:mint figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:zoe7XVdyD2d1AS/N/+Di7Xn1PAs559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:P05319 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-15456|uniprotkb:D6W227|ensemblfungi:YOL039W psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rla2_yeast(display_long)|uniprotkb:RPP2A(gene name)|psi-mi:RPP2A(display_short)|uniprotkb:L12EIB(gene name synonym)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RPL44(gene name synonym)|uniprotkb:RPLA2(gene name synonym)|uniprotkb:L12eIB(gene name synonym)|uniprotkb:YP2alpha(gene name synonym)|uniprotkb:L44(gene name synonym)|uniprotkb:YOL039W(locus name)|uniprotkb:Large ribosomal subunit protein P2-A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 refseq:NP_014603.1|sgd:S000005399|ensemblfungi:YOL039W(gene)|ensemblfungi:YOL039W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:4V6I|dip:DIP-2506N - crc64:758D3FB130DF2357 - figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:bvmZbhGsNuMJEdAv9ac1wD6Y+Rs559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:P02400 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-15464|uniprotkb:D6VT16|ensemblfungi:YDR382W psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rla4_yeast(display_long)|uniprotkb:RPP2B(gene name)|psi-mi:RPP2B(display_short)|uniprotkb:L12EIA(gene name synonym)|uniprotkb:RPL45(gene name synonym)|uniprotkb:RPLA4(gene name synonym)|uniprotkb:L12eIA(gene name synonym)|uniprotkb:YP2beta(gene name synonym)|uniprotkb:L45(gene name synonym)|uniprotkb:YL44C(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:YDR382W(locus name)|uniprotkb:Large ribosomal subunit protein P2-B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 sgd:S000002790|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|refseq:NP_010670.3|ensemblfungi:YDR382W(gene)|ensemblfungi:YDR382W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:3N2D|rcsb pdb:3N3X|dip:DIP-580N - crc64:758D3FB130DF2357 crc64:EC45406CB5F199F4 figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:dvY8zJb/i5nIRnNekgTQdY9Novs559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:Q3E754 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-852918|uniprotkb:P05760|uniprotkb:D6VW49|ensemblfungi:YJL136C psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rs21b_yeast(display_long)|uniprotkb:S26(gene name synonym)|uniprotkb:YS25(gene name synonym)|uniprotkb:RPS21B(gene name)|psi-mi:RPS21B(display_short)|uniprotkb:RPS25B(gene name synonym)|uniprotkb:YJL136C(locus name)|uniprotkb:J0664(orf name)|uniprotkb:RPS26B(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS21-B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 refseq:NP_012399.1|sgd:S000003672|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|ensemblfungi:YJL136C(gene)|ensemblfungi:YJL136C_mRNA(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|reactome:R-SCE-6791226|reactome:R-SCE-72649 - crc64:758D3FB130DF2357 - figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:lfc/hCpIglGsP8zhgniJx/qODJA559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:P32561 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 - crc64:758D3FB130DF2357 crc64:34FFD72A7E7425DB figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P53127 uniprotkb:Q03214 intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16545008|imex:IM-26191-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 - crc64:758D3FB130DF2357 - figure legend:Fig. 1B, Table 2, Supp Table 1|comment:"It is stated (under Table 2) that:- \"While not previously reported as contaminants, these proteins are highly abundant (31) and are therefore likely contaminants.\" Notably proteins Rps21b, Rpp2b, Rpl19b, Rps6b, Rpp2a, Rpl18b."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rigid:51T29a72dwFBoenPYVdBop5qVHU false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P0CX38 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-7432889|intact:MINT-8285672|uniprotkb:P05751|uniprotkb:Q02894|uniprotkb:D6VQH5|uniprotkb:P02365|ensemblfungi:YBR181C|ensemblfungi:YPL090C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rs6b_yeast(display_long)|uniprotkb:RPS6B(gene name)|psi-mi:RPS6B(display_short)|uniprotkb:RP9(gene name synonym)|uniprotkb:RPS102(gene name synonym)|uniprotkb:YS4(gene name synonym)|uniprotkb:YBR1244(orf name)|uniprotkb:YBR181C(locus name)|uniprotkb:RPS10A(gene name synonym)|uniprotkb:S10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6-B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-6791226|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|refseq:NP_015235.1|interpro:IPR001377(Ribosomal protein S6e)|sgd:S000000385|refseq:NP_009740.3|ensemblfungi:YBR181C(gene)|ensemblfungi:YBR181C_mRNA(transcript)|ensemblfungi:YPL090C(gene)|ensemblfungi:YPL090C_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032040"(small-subunit processome)|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-SCE-72649|reactome:R-SCE-1799339 - crc64:34FFD72A7E7425DB comment:mint figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:EeJ5VG5FWn5tAtQo5cEsiAM6K7k559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P0CX52 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-5234556|uniprotkb:D6VRR6|uniprotkb:P26787|uniprotkb:P40213|ensemblfungi:YDL083C|ensemblfungi:YMR143W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rs16b_yeast(display_long)|uniprotkb:YDL083C(locus name)|uniprotkb:Small ribosomal subunit protein uS9-B(gene name synonym)|uniprotkb:RPS16B(gene name)|psi-mi:RPS16B(display_short)|uniprotkb:RP61R(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 reactome:R-SCE-156827|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|sgd:S000002241|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR020574|refseq:NP_010200.1|refseq:NP_013863.2|reactome:R-SCE-1799339|ensemblfungi:YDL083C(gene)|ensemblfungi:YDL083C_mRNA(transcript)|ensemblfungi:YMR143W(gene)|ensemblfungi:YMR143W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|reactome:R-SCE-6791226|reactome:R-SCE-72649 - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:nYZIjMTFihS9LlO/ZqInWLF+BZc559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P16861 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-9428|ensemblfungi:YGR240C|uniprotkb:D6VV20 psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:pfka1_yeast(display_long)|uniprotkb:PFK1(gene name)|psi-mi:PFK1(display_short)|uniprotkb:YGR240C(locus name)|uniprotkb:G8599(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_011756.1|sgd:S000003472|ensemblfungi:YGR240C(gene)|ensemblfungi:YGR240C_mRNA(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR040712|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|mint:P16861|dip:DIP-1505N - crc64:34FFD72A7E7425DB crc64:995B3DF7C7781B29 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:mqqXE8Cvcp019pDQsU01zBYUsCc559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q00955 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-4814|uniprotkb:D6W1J1|ensemblfungi:YNR016C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:acac_yeast(display_long)|uniprotkb:ACC1(gene name)|psi-mi:ACC1(display_short)|uniprotkb:ABP2(gene name synonym)|uniprotkb:MTR7(gene name synonym)|uniprotkb:N3175(orf name)|uniprotkb:YNR016C(locus name)|uniprotkb:FAS3(gene name synonym)|uniprotkb:Fatty acid synthetase 3(gene name synonym)|uniprotkb:mRNA transport-defective protein 7(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_014413.1|sgd:S000005299|dip:DIP-975N|mint:Q00955|ensemblfungi:YNR016C(gene)|ensemblfungi:YNR016C_mRNA(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0009317"(acetyl-CoA carboxylase complex)|go:"GO:0016743"(carboxyl- or carbamoyltransferase activity)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905502"(acetyl-CoA binding)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|rcsb pdb:1OD2|rcsb pdb:1OD4|rcsb pdb:1UYR|rcsb pdb:1UYS|rcsb pdb:1UYT|rcsb pdb:1UYV|rcsb pdb:1W2X|rcsb pdb:1W96|rcsb pdb:3H0J|rcsb pdb:3H0Q|rcsb pdb:3H0S|rcsb pdb:3K8X|rcsb pdb:3PGQ|rcsb pdb:3TV5|rcsb pdb:3TVU|rcsb pdb:3TVW|rcsb pdb:3TZ3|rcsb pdb:4WYO|rcsb pdb:4WZ8|rcsb pdb:5CS0|rcsb pdb:5CS4|rcsb pdb:5CSA|rcsb pdb:5CSK|rcsb pdb:5CSL|rcsb pdb:5CTB|rcsb pdb:5CTC|rcsb pdb:5CTE|rcsb pdb:5I6E|rcsb pdb:5TRC|reactome:R-SCE-163765|reactome:R-SCE-196780|reactome:R-SCE-200425|reactome:R-SCE-75105|rcsb pdb:1W93 - crc64:34FFD72A7E7425DB crc64:0A335AAD9B1F8308 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:zf1zvUJYyelChSf7blBKAnjVeoU559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P07342 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-9096|ensemblfungi:YMR108W|uniprotkb:D6VZT1 psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ilvb_yeast(display_long)|uniprotkb:ILV2(gene name)|psi-mi:ILV2(display_short)|uniprotkb:SMR1(gene name synonym)|uniprotkb:YMR108W(locus name)|uniprotkb:YM9718.07(orf name)|uniprotkb:Acetohydroxy-acid synthase catalytic subunit(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 ensemblfungi:YMR108W(gene)|ensemblfungi:YMR108W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003984"(acetolactate synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005948"(acetolactate synthase complex)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR012846(Acetolactate synthase, large subunit, biosynthetic)|interpro:IPR029035|interpro:IPR029061|interpro:IPR039368|rcsb pdb:1JSC|rcsb pdb:1N0H|rcsb pdb:1T9A|rcsb pdb:1T9B|rcsb pdb:1T9C|rcsb pdb:1T9D|rcsb pdb:5FEM|rcsb pdb:5IMS|rcsb pdb:5WKC|rcsb pdb:6BD3|rcsb pdb:6BD9|rcsb pdb:6U9D|refseq:NP_013826.1|sgd:S000004714|mint:P07342|dip:DIP-1104N - crc64:34FFD72A7E7425DB crc64:B03C4D0F38AA1362 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:9A0deezeL4n1dExQk1cgdggICGs559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P48589 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-16050|uniprotkb:Q02545|uniprotkb:D6W362|ensemblfungi:YOR369C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rs12_yeast(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym)|uniprotkb:YOR369C(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-6791226|reactome:R-SCE-72649|rcsb pdb:6Q8Y|sgd:S000005896|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR000530(Ribosomal protein S12e)|rcsb pdb:6HHQ|reactome:R-SCE-1799339|reactome:R-SCE-156827|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|ensemblfungi:YOR369C(gene)|ensemblfungi:YOR369C_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5FCI|rcsb pdb:5FCJ|refseq:NP_015014.3|rcsb pdb:5MEI|rcsb pdb:5TBW|interpro:IPR029064|rcsb pdb:5WYJ|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5TGM|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:5ON6|rcsb pdb:6FAI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:6EML|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6I7O|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6Y7C|rcsb pdb:6TB3|rcsb pdb:6TNU|rcsb pdb:6KE6|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6LQP|rcsb pdb:6LQU|rcsb pdb:6WDR|rcsb pdb:6WOO|rcsb pdb:6ZCE|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:qpHU4xAcqhuTjqmzj7uftYFlGJU559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P12612 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19045|uniprotkb:D6VSJ6|ensemblfungi:YDR212W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcpa_yeast(display_long)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:YDR212W(locus name)|uniprotkb:YD8142.13(orf name)|uniprotkb:YD8142B.04(orf name)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_010498.1|sgd:S000002620|ensemblfungi:YDR212W(gene)|ensemblfungi:YDR212W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2965N|mint:P12612 - crc64:34FFD72A7E7425DB crc64:02C625D329359E61 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:xWMsvY106Y6yQ54SOif2UlScafM559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P01120 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-14838|uniprotkb:Q45U01|uniprotkb:D6W181|ensemblfungi:YNL098C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ras2_yeast(display_long)|uniprotkb:RAS2(gene name)|psi-mi:RAS2(display_short)|uniprotkb:ASC1(gene name synonym)|uniprotkb:CTN5(gene name synonym)|uniprotkb:GLC5(gene name synonym)|uniprotkb:YNL098C(locus name)|uniprotkb:N2198(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_014301.1|sgd:S000005042|go:"GO:0032880"(regulation of protein localization)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0097271"(protein localization to bud neck)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-SCE-9696273|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016236"(macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|ensemblfungi:YNL098C(gene)|ensemblfungi:YNL098C_mRNA(transcript)|go:"GO:0000411"(positive regulation of transcription by galactose)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007265"(Ras protein signal transduction)|dip:DIP-2263N|mint:P01120 - crc64:34FFD72A7E7425DB crc64:6CAAAC531EEAE92F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:MJS2Zuw6xxrxaLE6r3omwm+2vm4559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P29311 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-3661|uniprotkb:Q06854|uniprotkb:D3DM86|ensemblfungi:YER177W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:bmh1_yeast(display_long)|uniprotkb:YER177W(locus name)|uniprotkb:BMH1(gene name)|psi-mi:BMH1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 sgd:S000000979|refseq:NP_011104.3|dip:DIP-4313N|mint:P29311|ensemblfungi:YER177W(gene)|ensemblfungi:YER177W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030437"(ascospore formation)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:5N6N|rcsb pdb:6QK8 - crc64:34FFD72A7E7425DB crc64:0A234167E313688B figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:RnX8tqsjlxM+7Mi+Thlhc1XrTy4559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P34233 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-3027|uniprotkb:D6VX15|ensemblfungi:YKL185W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ash1_yeast(display_long)|uniprotkb:ASH1(gene name)|psi-mi:ASH1(display_short)|uniprotkb:Daughter cells HO repressor protein(gene name synonym)|uniprotkb:YKL185W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_012736.1|sgd:S000001668|dip:DIP-8053N|mint:P34233|ensemblfungi:YKL185W(gene)|ensemblfungi:YKL185W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005933"(cellular bud)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:1900461"(positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter)|go:"GO:1900477"(negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type) - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:OKR/uOyZ4UWgJUNx3oB/PBhzfAc559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q08923 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-33349|uniprotkb:Q6B1X3|uniprotkb:D6W3I7|ensemblfungi:YPL181W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:cti6_yeast(display_long)|uniprotkb:Transcriptional regulatory protein CTI6(gene name synonym)|uniprotkb:CYC8-TUP1-interacting protein 6(gene name synonym)|uniprotkb:YPL181W(locus name)|uniprotkb:CTI6(gene name)|psi-mi:CTI6(display_short)|uniprotkb:RXT1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_015144.1|sgd:S000006102|ensemblfungi:YPL181W(gene)|ensemblfungi:YPL181W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008134"(transcription factor binding)|mint:Q08923|dip:DIP-2958N|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787 - crc64:34FFD72A7E7425DB crc64:5123C56BB86ED991 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:cinec0yfaziNc2oeW6HGnp8fL60559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P50947 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-28808|uniprotkb:Q45TZ9|uniprotkb:D6W183|ensemblfungi:YNL097C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:pho23_yeast(display_long)|uniprotkb:PHO23(gene name)|psi-mi:PHO23(display_short)|uniprotkb:N2205(orf name)|uniprotkb:YNL097C(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 sgd:S000005041|refseq:NP_014302.3|dip:DIP-4243N|mint:P50947|ensemblfungi:YNL097C(gene)|ensemblfungi:YNL097C_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016573"(histone acetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|reactome:R-SCE-3214847|reactome:R-SCE-3899300|reactome:R-SCE-6804758|reactome:R-SCE-6811555 - crc64:34FFD72A7E7425DB crc64:3BF7B519E77ED6EF figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:N8KCC01xvIWGV9jdfQ/ZzizkIws559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P39079 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19077|uniprotkb:D6VSH1|ensemblfungi:YDR188W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcpz_yeast(display_long)|uniprotkb:CCT6(gene name)|psi-mi:CCT6(display_short)|uniprotkb:TCP20(gene name synonym)|uniprotkb:TCP6(gene name synonym)|uniprotkb:YDR188W(locus name)|uniprotkb:YD9395.21(orf name)|uniprotkb:CCT-zeta(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 sgd:S000002596|ensemblfungi:YDR188W(gene)|ensemblfungi:YDR188W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|rcsb pdb:6KRD|refseq:NP_010474.3|dip:DIP-6401N|mint:P39079 - crc64:34FFD72A7E7425DB crc64:7D2A2AB4526D3DB4 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:D9HUMBTSH1Tsm/XHNMIOdd6YxEw559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P40413 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19059|uniprotkb:D6VWN5|ensemblfungi:YJR064W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcpe_yeast(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:TCP5(gene name synonym)|uniprotkb:YJR064W(locus name)|uniprotkb:J1752(orf name)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_012598.1|sgd:S000003825|ensemblfungi:YJR064W(gene)|ensemblfungi:YJR064W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-2205N - crc64:34FFD72A7E7425DB crc64:8CDAF88C6403655F figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:wqguMbwgiNZnGVuBiU47NsFxtN0559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q07458 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-33895|uniprotkb:D6VRS3|ensemblfungi:YDL076C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rxt3_yeast(display_long)|uniprotkb:RXT3(gene name)|psi-mi:RXT3(display_short)|uniprotkb:YDL076C(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_010207.1|sgd:S000002234|mint:Q07458|dip:DIP-1797N|ensemblfungi:YDL076C(gene)|ensemblfungi:YDL076C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016575"(histone deacetylation)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR013951(Histone deacetylation protein Rxt3) - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:6fTNwtXcJvNN0VTp4LQ9XhNtLq8559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P38255 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-21537|uniprotkb:D6VQ96|ensemblfungi:YBR095C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rxt2_yeast(display_long)|uniprotkb:YBR095C(locus name)|uniprotkb:YBR0822(orf name)|uniprotkb:RXT2(gene name)|psi-mi:RXT2(display_short)|uniprotkb:RAF60(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_009653.2|sgd:S000000299|mint:P38255|dip:DIP-6755N|ensemblfungi:YBR095C(gene)|ensemblfungi:YBR095C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:1990483"(Clr6 histone deacetylase complex I'')|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR013904(RXT2-like, N-terminal)|interpro:IPR039602 - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:vyk+t+m5t/bXnmpMYfeVXe4I1W0559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P42943 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19067|uniprotkb:D6VW73|ensemblfungi:YJL111W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcph_yeast(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:YJL111W(locus name)|uniprotkb:J0804(orf name)|uniprotkb:CCT-eta(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_012424.1|sgd:S000003647|ensemblfungi:YJL111W(gene)|ensemblfungi:YJL111W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6758N - crc64:34FFD72A7E7425DB crc64:A428FEC2ACD54B4B figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:gdAc3WzZTLalRJcEvo9wnkyKwug559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P39076 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19049|uniprotkb:D6VVE5|ensemblfungi:YIL142W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcpb_yeast(display_long)|uniprotkb:YIL142W(locus name)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:BIN3(gene name synonym)|uniprotkb:TCP2(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_012124.1|sgd:S000001404|ensemblfungi:YIL142W(gene)|ensemblfungi:YIL142W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6798695|reactome:R-SCE-6814122|dip:DIP-4451N|mint:P39076 - crc64:34FFD72A7E7425DB crc64:C5DB2BC3660EC7E6 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:Jam3hUOl+RaeXhWHmWXFFfczKaI559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q12432 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-6281|uniprotkb:D6W433|ensemblfungi:YPR023C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:eaf3_yeast(display_long)|uniprotkb:EAF3(gene name)|psi-mi:EAF3(display_short)|uniprotkb:YPR023C(locus name)|uniprotkb:YP9367.03C(orf name)|uniprotkb:ESA1-associated factor 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_015348.1|sgd:S000006227|ensemblfungi:YPR023C(gene)|ensemblfungi:YPR023C_mRNA(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|dip:DIP-2871N|mint:Q12432|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043487"(regulation of RNA stability)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038217|rcsb pdb:2K3X|rcsb pdb:2K3Y|rcsb pdb:3E9F|rcsb pdb:3E9G|rcsb pdb:6K5W - crc64:34FFD72A7E7425DB crc64:63758DE9510D70DC figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:20fPAcvnQSzI0ojylZ07IW3u5CI559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P31385 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-5755|uniprotkb:Q86ZS5|uniprotkb:D6VPK5|ensemblfungi:YAL013W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:dep1_yeast(display_long)|uniprotkb:DEP1(gene name)|psi-mi:DEP1(display_short)|uniprotkb:FUN54(gene name synonym)|uniprotkb:YAL013W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_009389.3|sgd:S000000011|go:"GO:0016575"(histone deacetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|ensemblfungi:YAL013W(gene)|ensemblfungi:YAL013W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-5922N|mint:P31385|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR013907(Sds3-like)|reactome:R-SCE-3214815 - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:85f0flYXDpDnUREyKn0bQ7fUO3g559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q03010 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-20070|uniprotkb:P87330|uniprotkb:D6W3M9|ensemblfungi:YPL139C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ume1_yeast(display_long)|uniprotkb:UME1(gene name)|psi-mi:UME1(display_short)|uniprotkb:WTM3(gene name synonym)|uniprotkb:YPL139C(locus name)|uniprotkb:LPI7C(orf name)|uniprotkb:WD repeat-containing transcriptional modulator 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_015186.1|sgd:S000006060|ensemblfungi:YPL139C(gene)|ensemblfungi:YPL139C_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070210"(Rpd3L-Expanded complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-5290N|mint:Q03010 - crc64:34FFD72A7E7425DB crc64:AA6F60448B7BCBA9 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:radf8gBaPrKRK281JuKAYZprO34559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q04779 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-28153|uniprotkb:D6VZP9|ensemblfungi:YMR075W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rco1_yeast(display_long)|uniprotkb:YM9916.14(orf name)|uniprotkb:YMR075W(locus name)|uniprotkb:RCO1(gene name)|psi-mi:RCO1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_013791.1|sgd:S000004680|dip:DIP-1959N|mint:Q04779|ensemblfungi:YMR075W(gene)|ensemblfungi:YMR075W_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0005634"(nucleus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060195"(negative regulation of antisense RNA transcription)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787 - crc64:34FFD72A7E7425DB crc64:CFC282DC9A782E5C figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:5TrczzmnA5cA2yFTxM2rueJyA8c559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P40505 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-16809|ensemblfungi:YIL084C|uniprotkb:D6VVK2 psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:sds3_yeast(display_long)|uniprotkb:YIL084C(locus name)|uniprotkb:SDS3(gene name)|psi-mi:SDS3(display_short)|uniprotkb:Suppressor of defective silencing protein 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 ensemblfungi:YIL084C(gene)|ensemblfungi:YIL084C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0016575"(histone deacetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070822"(Sin3-type complex)|go:"GO:2000217"(regulation of invasive growth in response to glucose limitation)|interpro:IPR013907(Sds3-like)|reactome:R-SCE-3214815|refseq:NP_012182.1|sgd:S000001346|dip:DIP-2706N|mint:P40505 - crc64:34FFD72A7E7425DB crc64:4A6186E68BFE0CC7 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:Ri0JEWQXqBHUb95AnRdMYEkSz+Y559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P05319 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-15456|uniprotkb:D6W227|ensemblfungi:YOL039W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rla2_yeast(display_long)|uniprotkb:RPP2A(gene name)|psi-mi:RPP2A(display_short)|uniprotkb:L12EIB(gene name synonym)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RPL44(gene name synonym)|uniprotkb:RPLA2(gene name synonym)|uniprotkb:L12eIB(gene name synonym)|uniprotkb:YP2alpha(gene name synonym)|uniprotkb:L44(gene name synonym)|uniprotkb:YOL039W(locus name)|uniprotkb:Large ribosomal subunit protein P2-A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_014603.1|sgd:S000005399|ensemblfungi:YOL039W(gene)|ensemblfungi:YOL039W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:4V6I|dip:DIP-2506N - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:bvmZbhGsNuMJEdAv9ac1wD6Y+Rs559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P39078 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19054|uniprotkb:Q07561|uniprotkb:D6VRK5|ensemblfungi:YDL143W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcpd_yeast(display_long)|uniprotkb:YDL143W(locus name)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:ANC2(gene name synonym)|uniprotkb:TCP4(gene name synonym)|uniprotkb:CCT-delta(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_010138.1|sgd:S000002302|ensemblfungi:YDL143W(gene)|ensemblfungi:YDL143W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6753N|mint:P39078 - crc64:34FFD72A7E7425DB crc64:F01146D76F4E850C figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:GCSpoIEgtQxu/8dbncxp/4AXEls559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P02400 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-15464|uniprotkb:D6VT16|ensemblfungi:YDR382W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:rla4_yeast(display_long)|uniprotkb:RPP2B(gene name)|psi-mi:RPP2B(display_short)|uniprotkb:L12EIA(gene name synonym)|uniprotkb:RPL45(gene name synonym)|uniprotkb:RPLA4(gene name synonym)|uniprotkb:L12eIA(gene name synonym)|uniprotkb:YP2beta(gene name synonym)|uniprotkb:L45(gene name synonym)|uniprotkb:YL44C(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:YDR382W(locus name)|uniprotkb:Large ribosomal subunit protein P2-B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 sgd:S000002790|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|refseq:NP_010670.3|ensemblfungi:YDR382W(gene)|ensemblfungi:YDR382W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:3N2D|rcsb pdb:3N3X|dip:DIP-580N - crc64:34FFD72A7E7425DB crc64:EC45406CB5F199F4 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:dvY8zJb/i5nIRnNekgTQdY9Novs559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P39077 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-19063|uniprotkb:D6VWG3|ensemblfungi:YJL014W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:tcpg_yeast(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:BIN2(gene name synonym)|uniprotkb:TCP3(gene name synonym)|uniprotkb:YJL014W(locus name)|uniprotkb:J1336(orf name)|uniprotkb:CCT-gamma(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_012520.1|sgd:S000003551|ensemblfungi:YJL014W(gene)|ensemblfungi:YJL014W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|rcsb pdb:4V81|rcsb pdb:4V8R|rcsb pdb:4V94|rcsb pdb:5GW4|rcsb pdb:5GW5|rcsb pdb:6KRD|rcsb pdb:6KRE|rcsb pdb:6KS6|rcsb pdb:6KS7|rcsb pdb:6KS8|reactome:R-SCE-390471|reactome:R-SCE-6814122|dip:DIP-6400N - crc64:34FFD72A7E7425DB crc64:5C5AFF3D67D9A3B6 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:6+oG9OJ6pgpDE7kXLlirAMBLjJo559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q03214 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 - crc64:34FFD72A7E7425DB - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:P53127 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16546077|imex:IM-26191-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 - crc64:34FFD72A7E7425DB crc64:758D3FB130DF2357 figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rigid:ta0hWLK7mX5NYZmhHPeB6LVnmV8 false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03214 uniprotkb:P0CX39 intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W intact:EBI-7043100|ensemblfungi:YBL072C|ensemblfungi:YER102W|uniprotkb:D3DM09|uniprotkb:A2TBM0|intact:MINT-8289650|intact:MINT-8285681|uniprotkb:P22801|uniprotkb:P05754|uniprotkb:A2TBP0 psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:rs8a_yeast(display_long)|uniprotkb:RPS8A(gene name)|psi-mi:RPS8A(display_short)|uniprotkb:RP19(gene name synonym)|uniprotkb:RPS14A(gene name synonym)|uniprotkb:S14(gene name synonym)|uniprotkb:YS9(gene name synonym)|uniprotkb:YBL06.05(orf name)|uniprotkb:YBL0613(orf name)|uniprotkb:YBL072C(locus name)|uniprotkb:Small ribosomal subunit protein eS8-A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16553400|imex:IM-26191-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5LL6|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J77|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DGE|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:7AJT|rcsb pdb:7AJU|ensemblfungi:YBL072C(gene)|ensemblfungi:YBL072C_mRNA(transcript)|ensemblfungi:YER102W(gene)|ensemblfungi:YER102W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|interpro:IPR042563|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|reactome:R-SCE-6791226|reactome:R-SCE-72649|rcsb pdb:5DAT|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5WYJ|rcsb pdb:5WYK|sgd:S000000168|interpro:IPR022309|interpro:IPR018283|refseq:NP_011028.1|refseq:NP_009481.1|interpro:IPR001047(Ribosomal protein S8e)|rcsb pdb:6LQQ|rcsb pdb:6LQR|reactome:R-SCE-156827|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6LQS|rcsb pdb:6LQP|rcsb pdb:5DC3|rcsb pdb:5I4L|rcsb pdb:5ON6|rcsb pdb:6FAI|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5LYB|rcsb pdb:5TGA|rcsb pdb:5TZS|rcsb pdb:6Q8Y|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6WDR|rcsb pdb:6LQT|rcsb pdb:5MEI|rcsb pdb:5TBW|rcsb pdb:5WLC|rcsb pdb:6EML|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6I7O|rcsb pdb:6WOO|rcsb pdb:6HHQ|reactome:R-SCE-1799339|rcsb pdb:6S47|rcsb pdb:6ZCE|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZU9|rcsb pdb:7A1G|rcsb pdb:6KE6|rcsb pdb:6Z6J|rcsb pdb:6Z6K|rcsb pdb:6ZVI|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6Y7C - - comment:mint figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rogid:jRfjhbkl8RQB7y95ol7hZ3Ggj2Y559292 rigid:wlQIdI/Mxw3OjaT/mPCmIbCBWcw false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03214 uniprotkb:P12709 intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W intact:EBI-7238|uniprotkb:D6VQJ0|ensemblfungi:YBR196C psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:g6pi_yeast(display_long)|uniprotkb:PGI1(gene name)|psi-mi:PGI1(display_short)|uniprotkb:YBR196C(locus name)|uniprotkb:YBR1406(orf name)|uniprotkb:Phosphoglucose isomerase(gene name synonym)|uniprotkb:Phosphohexose isomerase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16553400|imex:IM-26191-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 refseq:NP_009755.1|sgd:S000000400|mint:P12709|dip:DIP-1605N|ensemblfungi:YBR196C(gene)|ensemblfungi:YBR196C_mRNA(transcript)|go:"GO:0004347"(glucose-6-phosphate isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001672("Phosphoglucose isomerase (PGI)")|interpro:IPR018189|interpro:IPR023096|interpro:IPR035476|interpro:IPR035482|reactome:R-SCE-5628897|reactome:R-SCE-6798695|reactome:R-SCE-70171|reactome:R-SCE-70263 - - crc64:556D3D3B77EED052 figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rogid:hle82HMm3aAvYrUuuGoaxqyg/VA559292 rigid:wlQIdI/Mxw3OjaT/mPCmIbCBWcw false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03214 uniprotkb:P32561 intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16553400|imex:IM-26191-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 - - crc64:34FFD72A7E7425DB figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rigid:wlQIdI/Mxw3OjaT/mPCmIbCBWcw false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03214 uniprotkb:P53127 intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16553400|imex:IM-26191-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 - - crc64:758D3FB130DF2357 figure legend:Fig. 1C, Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rigid:wlQIdI/Mxw3OjaT/mPCmIbCBWcw false protein a tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P32561 uniprotkb:Q03214 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16555188|imex:IM-26191-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 - crc64:34FFD72A7E7425DB - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/30 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rigid:qttbOoVUQvF3sUt/l4F5aKK/i0E false - myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03214 uniprotkb:P53127 intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16583974|imex:IM-26191-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 - - crc64:758D3FB130DF2357 figure legend:Fig. 1D, 3A|comment:H2O2 treatment does not affect the levels of Snt2 and Rpd3 associating with Ecm5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/31 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rigid:7RuUD41WWPMxu2leKNtMLV/bl4Y false myc tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03214 uniprotkb:P32561 intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16583974|imex:IM-26191-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 - - crc64:34FFD72A7E7425DB figure legend:Fig. 1D, 3A|comment:H2O2 treatment does not affect the levels of Snt2 and Rpd3 associating with Ecm5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/31 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rigid:7RuUD41WWPMxu2leKNtMLV/bl4Y false myc tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32561 uniprotkb:P53127 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-23958|uniprotkb:D6VU17|ensemblfungi:YGL131C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:snt2_yeast(display_long)|uniprotkb:SNT2(gene name)|psi-mi:SNT2(display_short)|uniprotkb:Histone E3 ligase SNT2(gene name synonym)|uniprotkb:SANT domain-containing protein 2(gene name synonym)|uniprotkb:G2850(orf name)|uniprotkb:YGL131C(locus name)|uniprotkb:RING-type E3 ubiquitin transferase SNT2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16583989|imex:IM-26191-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_011384.1|sgd:S000003099|dip:DIP-6540N|mint:P53127|ensemblfungi:YGL131C(gene)|ensemblfungi:YGL131C_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0036205"(histone catabolic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048189"(Lid2 complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070211"(Snt2C complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017884|interpro:IPR019787|interpro:IPR029617|interpro:IPR034732|interpro:IPR043151 - crc64:34FFD72A7E7425DB crc64:758D3FB130DF2357 figure legend:Fig. 3B|comment:H2O2 treatment does not affect the levels of Snt2 and Rpd3 associating with Ecm5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/31 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:oPFtJFJdtdyigJhkyYlJnPDgeM0559292 rigid:7RuUD41WWPMxu2leKNtMLV/bl4Y false - green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32561 uniprotkb:Q03214 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-27382|uniprotkb:D6VZZ9|ensemblfungi:YMR176W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ecm5_yeast(display_long)|uniprotkb:YMR176W(locus name)|uniprotkb:YM8010.06(orf name)|uniprotkb:ECM5(gene name)|psi-mi:ECM5(display_short)|uniprotkb:Extracellular matrix protein 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Baker et al. (2013) imex:IM-26191|pubmed:23878396 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-16583989|imex:IM-26191-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_013901.1|sgd:S000004788|dip:DIP-6678N|reactome:R-SCE-3214842|ensemblfungi:YMR176W(gene)|ensemblfungi:YMR176W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070211"(Snt2C complex)|go:"GO:0071555"(cell wall organization)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431 - crc64:34FFD72A7E7425DB - figure legend:Fig. 3B|comment:H2O2 treatment does not affect the levels of Snt2 and Rpd3 associating with Ecm5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/10/30 2017/10/31 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:YKznIWMl0Ru8DKdAG1hnrA8e0Ts559292 rigid:7RuUD41WWPMxu2leKNtMLV/bl4Y false - myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)