#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-4399559 uniprotkb:Q8T0L3 dip:DIP-24261N intact:EBI-94930|uniprotkb:Q9V5A7|ensemblmetazoa:FBpp0087583 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:q8t0l3_drome(display_long)|uniprotkb:Uba1(gene name)|psi-mi:Uba1(display_short)|uniprotkb:2(gene name synonym)|uniprotkb:31(gene name synonym)|uniprotkb:DmUba1(gene name synonym)|uniprotkb:Dmel\CG1782(gene name synonym)|uniprotkb:E1(gene name synonym)|uniprotkb:FBtr0088499(gene name synonym)|uniprotkb:UBA-1(gene name synonym)|uniprotkb:Uba 1(gene name synonym)|uniprotkb:"l(2)03405"(gene name synonym)|uniprotkb:"l(2)05642"(gene name synonym)|uniprotkb:"l(2)s3484"(gene name synonym)|uniprotkb:uba-1(gene name synonym)|uniprotkb:uba1(gene name synonym)|uniprotkb:CG1782(orf name)|uniprotkb:Dmel_CG1782(orf name)|uniprotkb:UBA1(gene name synonym)|uniprotkb:Uba(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chang et al. (2013) pubmed:23873149|doi:10.1038/ncb2804|imex:IM-24847 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16066148|imex:IM-24847-1|dip:DIP-199855E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_477310.2|flybase:FBgn0023143|ensemblmetazoa:FBgn0023143(gene)|ensemblmetazoa:FBtr0088499(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016319"(mushroom body development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019915"(lipid storage)|go:"GO:0030425"(dendrite)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0040008"(regulation of growth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0046578"(regulation of Ras protein signal transduction)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|reactome:R-DME-8866652|reactome:R-DME-983168|interpro:IPR032420 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:y38Nty8aekehsZx9Gmai7Q7jD407227 rigid:+mo5fkvxM4OeuOlcX2UP3knAwZY false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9W2S2 uniprotkb:Q7JY94 intact:EBI-107050|ensemblmetazoa:FBpp0071427 intact:EBI-3402374|ensemblmetazoa:FBpp0085891 psi-mi:q9w2s2_drome(display_long)|uniprotkb:Atg-8a(gene name synonym)|uniprotkb:Atg8alpha(gene name synonym)|uniprotkb:Atg8a(gene name)|psi-mi:Atg8a(display_short)|uniprotkb:CG1534(gene name synonym)|uniprotkb:ATG8(gene name synonym)|uniprotkb:ATG8a(gene name synonym)|uniprotkb:Atg8(gene name synonym)|uniprotkb:Atg8A(gene name synonym)|uniprotkb:"BcDNA:LD05816"(gene name synonym)|uniprotkb:DmAtg8a(gene name synonym)|uniprotkb:Dmel\CG32672(gene name synonym)|uniprotkb:DrAtg8a(gene name synonym)|uniprotkb:LC3(gene name synonym)|uniprotkb:atg8(gene name synonym)|uniprotkb:atg8A(gene name synonym)|uniprotkb:atg8a(gene name synonym)|uniprotkb:dAtg8a(gene name synonym)|uniprotkb:CG32672(orf name)|uniprotkb:Dmel_CG32672(orf name) psi-mi:q7jy94_drome(display_long)|uniprotkb:Atg7(gene name)|psi-mi:Atg7(display_short)|uniprotkb:ATG7(gene name synonym)|uniprotkb:Dmel\CG5489(gene name synonym)|uniprotkb:atg-7(gene name synonym)|uniprotkb:atg7(gene name synonym)|uniprotkb:CG5489(orf name)|uniprotkb:Dmel_CG5489(orf name)|uniprotkb:dAtg7(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:ATG-7(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chang et al. (2013) pubmed:23873149|doi:10.1038/ncb2804|imex:IM-24847 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16066167|imex:IM-24847-2|dip:DIP-199856E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727447.1|flybase:FBgn0052672|dip:DIP-19734N|ensemblmetazoa:FBgn0052672(gene)|ensemblmetazoa:FBtr0071498(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031386"(protein tag)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0044753"(amphisome)|go:"GO:0044754"(autolysosome)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0061174"(type I terminal bouton)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|reactome:R-DME-1632852|reactome:R-DME-8854214 ensemblmetazoa:FBtr0086712(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0006497"(protein lipidation)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035096"(larval midgut cell programmed cell death)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044805"(late nucleophagy)|go:"GO:0048477"(oogenesis)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903706"(regulation of hemopoiesis)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|reactome:R-DME-1632852|reactome:R-DME-6798695|reactome:R-DME-983168|ensemblmetazoa:FBgn0034366(gene)|refseq:NP_611350.1|flybase:FBgn0034366|dip:DIP-61759N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:AQL8hLo1vjdWJ5jCY4wVRcS/AS47227 rogid:X4xTepX5W0UdAC7uIN/vE9MJVPs7227 rigid:W5N38ecSXLrFXJBSdNoYWcnVDoU false his tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)