#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13916481|imex:IM-25696-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U - crc64:1492473684F3894C crc64:1492473684F3894C figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rigid:dw/fJV+mYmhiU3b4EPAi5Wr46LE false yellow fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04387 uniprotkb:P13045 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7282|uniprotkb:D6VRZ6|ensemblfungi:YDR009W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal3_yeast(display_long)|uniprotkb:YD8119.14(orf name)|uniprotkb:YDR009W(locus name)|uniprotkb:GAL3(gene name)|psi-mi:GAL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-13916489|imex:IM-25696-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_010292.1|sgd:S000002416|mint:P13045|dip:DIP-5725N|ensemblfungi:YDR009W(gene)|ensemblfungi:YDR009W_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0045185"(maintenance of protein location)|interpro:IPR000705(Galactokinase)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:3V2U|rcsb pdb:3V5R - crc64:1492473684F3894C crc64:5852028EBDDC0F3B figure legend:Fig. 1|comment:Gal3 only bound to Gal80 in the presence of galactose and ATP.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:EtOtuZODEOlw/PgA2I0MimDXYsU559292 rigid:RPqavQmBFQNeKET25pY1c3p+S2A false ha tag:?-? mutation disrupting interaction strength:199-199 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-13916489|imex:IM-25696-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U - crc64:1492473684F3894C crc64:1492473684F3894C figure legend:Fig. 1|comment:Gal3 only bound to Gal80 in the presence of galactose and ATP.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rigid:RPqavQmBFQNeKET25pY1c3p+S2A false ha tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0030"(cross-linking study) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916517|imex:IM-25696-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U - crc64:1492473684F3894C crc64:1492473684F3894C figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rigid:dw/fJV+mYmhiU3b4EPAi5Wr46LE false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P04387 uniprotkb:P13045 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7282|uniprotkb:D6VRZ6|ensemblfungi:YDR009W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal3_yeast(display_long)|uniprotkb:YD8119.14(orf name)|uniprotkb:YDR009W(locus name)|uniprotkb:GAL3(gene name)|psi-mi:GAL3(display_short) psi-mi:"MI:0030"(cross-linking study) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916521|imex:IM-25696-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_010292.1|sgd:S000002416|mint:P13045|dip:DIP-5725N|ensemblfungi:YDR009W(gene)|ensemblfungi:YDR009W_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0045185"(maintenance of protein location)|interpro:IPR000705(Galactokinase)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:3V2U|rcsb pdb:3V5R - crc64:1492473684F3894C crc64:5852028EBDDC0F3B figure legend:Fig. 2|comment:Interaction observed in the presence of 25 mM galactose|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:EtOtuZODEOlw/PgA2I0MimDXYsU559292 rigid:RPqavQmBFQNeKET25pY1c3p+S2A false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0030"(cross-linking study) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13949887|imex:IM-25696-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U - crc64:1492473684F3894C crc64:1492473684F3894C figure legend:Supp Fig. 1|comment:Cross-linked 6×His-Gal80 oligomers were diminished in the presence of 6×His-Gal3 but not in the presence of 6×His-Gal3-E116G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/03/16 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rigid:UmtqngH1Ag38o4zfqLAK+lb6Hww false his tag:?-? his tag:?-? 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0030"(cross-linking study) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13949894|imex:IM-25696-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U - crc64:1492473684F3894C crc64:1492473684F3894C figure legend:Supp Fig. 1|comment:Cross-linked 6×His-Gal80 oligomers were diminished in the presence of 6×His-Gal3 but not in the presence of 6×His-Gal3-E116G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/03/16 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rigid:UmtqngH1Ag38o4zfqLAK+lb6Hww false his tag:?-? his tag:?-? 4 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P04387 uniprotkb:P04387 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:"MI:0276"(blue native page) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916540|imex:IM-25696-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U - crc64:1492473684F3894C crc64:1492473684F3894C figure legend:Fig. 3, supp fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rigid:dw/fJV+mYmhiU3b4EPAi5Wr46LE false mutation increasing interaction strength:351-351 mutation increasing interaction strength:351-351 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P04387 uniprotkb:P13045 intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W intact:EBI-7282|uniprotkb:D6VRZ6|ensemblfungi:YDR009W psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name) psi-mi:gal3_yeast(display_long)|uniprotkb:YD8119.14(orf name)|uniprotkb:YDR009W(locus name)|uniprotkb:GAL3(gene name)|psi-mi:GAL3(display_short) psi-mi:"MI:0276"(blue native page) Egriboz et al. (2013) imex:IM-25696|pubmed:23858060 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-13916535|imex:IM-25696-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U refseq:NP_010292.1|sgd:S000002416|mint:P13045|dip:DIP-5725N|ensemblfungi:YDR009W(gene)|ensemblfungi:YDR009W_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0045185"(maintenance of protein location)|interpro:IPR000705(Galactokinase)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|rcsb pdb:3V2U|rcsb pdb:3V5R - crc64:1492473684F3894C crc64:5852028EBDDC0F3B figure legend:Fig. 3|comment:Interaction observed in the presence of 25 mM galactose|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/02/17 2017/02/17 rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292 rogid:EtOtuZODEOlw/PgA2I0MimDXYsU559292 rigid:RPqavQmBFQNeKET25pY1c3p+S2A false mutation with no effect:351-351 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)