#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P29469 uniprotkb:P09119 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064928|imex:IM-21590-1|dip:DIP-45155E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:13645F65BEAB5EE8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rigid:UI56ScufMG5JUyPb/rnNkvjvRM0 false - maltose binding protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P24279 uniprotkb:P09119 intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064976|imex:IM-21590-3|dip:DIP-192001E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 psi-mi:"MI:0465"(dip) crc64:43DD4DACAF4456DC crc64:13645F65BEAB5EE8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rigid:vP8fiAeMIEuihZr8QZepKLdiUIU false glutathione s tranferase tag:n-n maltose binding protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P09119 uniprotkb:P47112 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:099992C0E3CCA726 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P29469 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:F38FF682581B0EC0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P24279 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:43DD4DACAF4456DC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P30665 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:382D542AE38975E3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P29496 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:01D9DE208A091CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P53091 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:03AB793134E64A50 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P38132 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-4300|uniprotkb:D6VQK0|ensemblfungi:YBR202W psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:mcm7_yeast(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:YBR202W(locus name)|uniprotkb:YBR1441(orf name)|uniprotkb:CDC47(gene name synonym)|uniprotkb:Cell division control protein 47(gene name synonym)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 dip:DIP-2408N|sgd:S000000406|refseq:NP_009761.4|mint:P38132|ensemblfungi:YBR202W(gene)|ensemblfungi:YBR202W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:ADA66C719D96DB4A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:OJMt3vgMFg5we7rPkQSmkxbL1dA559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P54784 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:BDAA9D3E40B4B76A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P32833 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:486E3E5CE353807F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P54790 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:3FAAEE3F645D3F9C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P54791 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:ACF064F2C633F13F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P50874 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874 psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:1FE5DE28AFF6B41C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09119 uniprotkb:P38826 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064947|imex:IM-21590-2|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N psi-mi:"MI:0465"(dip) crc64:13645F65BEAB5EE8 crc64:22803C70378B7E85 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29469 uniprotkb:P38132 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-4300|uniprotkb:D6VQK0|ensemblfungi:YBR202W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:mcm7_yeast(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:YBR202W(locus name)|uniprotkb:YBR1441(orf name)|uniprotkb:CDC47(gene name synonym)|uniprotkb:Cell division control protein 47(gene name synonym)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N dip:DIP-2408N|sgd:S000000406|refseq:NP_009761.4|mint:P38132|ensemblfungi:YBR202W(gene)|ensemblfungi:YBR202W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:ADA66C719D96DB4A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:OJMt3vgMFg5we7rPkQSmkxbL1dA559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P53091 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-10556|uniprotkb:Q870M9|ensemblfungi:YGL201C|uniprotkb:D6VTV3 psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:mcm6_yeast(display_long)|uniprotkb:YGL201C(locus name)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N ensemblfungi:YGL201C(gene)|refseq:NP_011314.2|sgd:S000003169|ensemblfungi:YGL201C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5V8F|mint:P53091|dip:DIP-1294N psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:03AB793134E64A50 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:b2Pak0d6eENHIzSFaBge/kPQceU559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P29496 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-10549|ensemblfungi:YLR274W|uniprotkb:D6VYS1 psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:mcm5_yeast(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:YLR274W(locus name)|uniprotkb:L9328.1(orf name)|uniprotkb:Cell division control protein 46(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N refseq:NP_013376.1|sgd:S000004264|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:3JC5|rcsb pdb:6WGG|rcsb pdb:6WGI|ensemblfungi:YLR274W(gene)|ensemblfungi:YLR274W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|reactome:R-SCE-68949|reactome:R-SCE-69052|reactome:R-SCE-68962|dip:DIP-2406N psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:01D9DE208A091CF2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:a8UgYOklJ5vWqhA0hbQTCWNQg0Y559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P30665 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-4326|uniprotkb:D6W429|ensemblfungi:YPR019W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:mcm4_yeast(display_long)|uniprotkb:MCM4(gene name)|psi-mi:MCM4(display_short)|uniprotkb:HCD21(gene name synonym)|uniprotkb:YPR019W(locus name)|uniprotkb:YP9531.13(orf name)|uniprotkb:CDC54(gene name synonym)|uniprotkb:Cell division control protein 54(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N dip:DIP-2409N|refseq:NP_015344.1|sgd:S000006223|mint:P30665|ensemblfungi:YPR019W(gene)|ensemblfungi:YPR019W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:382D542AE38975E3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:KpsdSZBisjpmXnNAJTZncPINxYI559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P24279 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-10541|ensemblfungi:YEL032W|uniprotkb:D3DLL7 psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:mcm3_yeast(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:YEL032W(locus name)|uniprotkb:SYGP-ORF23(orf name)|uniprotkb:Minichromosome maintenance protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N refseq:NP_010882.1|sgd:S000000758|go:"GO:0005524"(ATP binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1904931"(MCM complex binding)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:6EYC|rcsb pdb:6F0L|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGC|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:5XF8|ensemblfungi:YEL032W(gene)|ensemblfungi:YEL032W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|mint:P24279|dip:DIP-2407N psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:43DD4DACAF4456DC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:OsFbdaTeE1vPQObriGt5M6mTPzk559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P47112 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-25503|uniprotkb:D6VWL7|ensemblfungi:YJR046W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:cdt1_yeast(display_long)|uniprotkb:YJR046W(locus name)|uniprotkb:J1641(orf name)|uniprotkb:TAH11(gene name)|psi-mi:TAH11(display_short)|uniprotkb:CDT1(gene name synonym)|uniprotkb:SID2(gene name synonym)|uniprotkb:SIC1 indispensable protein 2(gene name synonym)|uniprotkb:Topoisomerase-A hypersensitive protein 11(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N sgd:S000003807|refseq:NP_012580.1|dip:DIP-7948N|ensemblfungi:YJR046W(gene)|ensemblfungi:YJR046W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0051301"(cell division)|interpro:IPR032054|interpro:IPR038090|rcsb pdb:5ME9|rcsb pdb:5MEA|rcsb pdb:5MEB|rcsb pdb:5MEC|rcsb pdb:5V8F|rcsb pdb:5XF8|rcsb pdb:6WGG|rcsb pdb:6WGI psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:099992C0E3CCA726 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:bhL1vrVCG3mbWsF2S5nRT+i5fqw559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P09119 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-4447|uniprotkb:D6VVZ7|ensemblfungi:YJL194W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:cdc6_yeast(display_long)|uniprotkb:CDC6(gene name)|psi-mi:CDC6(display_short)|uniprotkb:J0347(orf name)|uniprotkb:YJL194W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N refseq:NP_012341.1|sgd:S000003730|mint:P09119|dip:DIP-2267N|ensemblfungi:YJL194W(gene)|ensemblfungi:YJL194W_mRNA(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0051301"(cell division)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR015163(CDC6, C terminal)|interpro:IPR016314(Cell division control, Cdc6)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|rcsb pdb:5V8F|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68689|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69017 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:13645F65BEAB5EE8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:JR9a6JdKg9hu4gkYo3Df0KrSkis559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P38826 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:22803C70378B7E85 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P50874 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:1FE5DE28AFF6B41C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P54791 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:ACF064F2C633F13F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P54790 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:3FAAEE3F645D3F9C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P32833 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:486E3E5CE353807F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P29469 uniprotkb:P54784 intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7 intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym) psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sun et al. (2013) pubmed:23851460|doi:10.1038/nsmb.2629|imex:IM-21590 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16064997|imex:IM-21590-4|dip:DIP-192000E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784 psi-mi:"MI:0465"(dip) crc64:F38FF682581B0EC0 crc64:BDAA9D3E40B4B76A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292 rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292 rigid:Xi4ZDQRfzyvA4pbaA5Y5vsb8ItI false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining)