#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11974 uniprotkb:P11974 intact:EBI-7133357|intact:MINT-6824949|uniprotkb:O18919|uniprotkb:Q29501 intact:EBI-7133357|intact:MINT-6824949|uniprotkb:O18919|uniprotkb:Q29501 psi-mi:kpym_rabit(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym) psi-mi:kpym_rabit(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064327|imex:IM-21554-1|dip:DIP-191945E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P11974|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|rcsb pdb:1A49|rcsb pdb:1A5U|rcsb pdb:1AQF|rcsb pdb:1F3W|rcsb pdb:1F3X|rcsb pdb:1PKN|rcsb pdb:2G50|rcsb pdb:3N25|refseq:NP_001182574.1|refseq:NP_001182573.1|dip:DIP-47514N mint:P11974|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|rcsb pdb:1A49|rcsb pdb:1A5U|rcsb pdb:1AQF|rcsb pdb:1F3W|rcsb pdb:1F3X|rcsb pdb:1PKN|rcsb pdb:2G50|rcsb pdb:3N25|refseq:NP_001182574.1|refseq:NP_001182573.1|dip:DIP-47514N psi-mi:"MI:0465"(dip) comment:mint|function:"Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP" comment:mint|function:"Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") - 2017/08/07 2017/08/10 rogid:oHQI4W/ix1kaSA2xfXYpnn2l8Tw9986 rogid:oHQI4W/ix1kaSA2xfXYpnn2l8Tw9986 rigid:Awgr/vAjn4rYuEYFKd/qGI0DbCM false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00722 uniprotkb:P00722 intact:EBI-369998|uniprotkb:Q2MC80|ensemblbacteria:AAC73447|ensemblbacteria:BAE76126 intact:EBI-369998|uniprotkb:Q2MC80|ensemblbacteria:AAC73447|ensemblbacteria:BAE76126 psi-mi:bgal_ecoli(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:b0344(locus name)|uniprotkb:JW0335(locus name)|uniprotkb:Lactase(gene name synonym) psi-mi:bgal_ecoli(display_long)|uniprotkb:lacZ(gene name)|psi-mi:lacZ(display_short)|uniprotkb:b0344(locus name)|uniprotkb:JW0335(locus name)|uniprotkb:Lactase(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064375|imex:IM-21554-4|dip:DIP-191946E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAC73447(transcript)|ensemblbacteria:b0344(gene)|ensemblbacteria:BAE76126(gene)|ensemblbacteria:BAE76126(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005990"(lactose catabolic process)|go:"GO:0009341"(beta-galactosidase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031420"(alkali metal ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR023230|interpro:IPR023232|interpro:IPR023933|interpro:IPR032312|interpro:IPR036156|rcsb pdb:1DP0|rcsb pdb:1F4A|rcsb pdb:1F4H|rcsb pdb:1HN1|rcsb pdb:1JYN|rcsb pdb:1JYV|rcsb pdb:1JYW|rcsb pdb:1JYX|rcsb pdb:1JZ2|rcsb pdb:1JZ3|rcsb pdb:1JZ4|rcsb pdb:1JZ5|rcsb pdb:1JZ6|rcsb pdb:1JZ7|rcsb pdb:1JZ8|rcsb pdb:1PX3|rcsb pdb:1PX4|rcsb pdb:3CZJ|rcsb pdb:3DYM|rcsb pdb:3DYO|rcsb pdb:3DYP|rcsb pdb:3E1F|rcsb pdb:3I3B|rcsb pdb:3I3D|rcsb pdb:3I3E|rcsb pdb:3IAP|rcsb pdb:6DRV|rcsb pdb:6KUZ|rcsb pdb:6TSH|rcsb pdb:6TSK|rcsb pdb:6TTE|rcsb pdb:6X1Q|rcsb pdb:7BRS|rcsb pdb:7BTK|rcsb pdb:3IAQ|rcsb pdb:3J7H|rcsb pdb:3MUY|rcsb pdb:3MUZ|rcsb pdb:3MV0|rcsb pdb:3MV1|rcsb pdb:3SEP|rcsb pdb:3T08|rcsb pdb:3T09|rcsb pdb:3T0A|rcsb pdb:3T0B|rcsb pdb:3T0D|rcsb pdb:3T2O|rcsb pdb:3T2P|rcsb pdb:3T2Q|rcsb pdb:3VD3|rcsb pdb:3VD4|rcsb pdb:3VD5|rcsb pdb:3VD7|rcsb pdb:3VD9|rcsb pdb:3VDA|rcsb pdb:3VDB|rcsb pdb:3VDC|rcsb pdb:4CKD|rcsb pdb:4DUV|rcsb pdb:4DUW|rcsb pdb:4DUX|rcsb pdb:4TTG|rcsb pdb:4V40|rcsb pdb:4V41|rcsb pdb:4V44|rcsb pdb:4V45|rcsb pdb:5A1A|rcsb pdb:6CVM|refseq:WP_000177906.1|refseq:NP_414878.1|dip:DIP-10081N ensemblbacteria:AAC73447(transcript)|ensemblbacteria:b0344(gene)|ensemblbacteria:BAE76126(gene)|ensemblbacteria:BAE76126(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005990"(lactose catabolic process)|go:"GO:0009341"(beta-galactosidase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031420"(alkali metal ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR004199(Glycoside hydrolase, family 42, domain 5)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014718(Glycoside hydrolase-type carbohydrate-binding, subgroup)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR023230|interpro:IPR023232|interpro:IPR023933|interpro:IPR032312|interpro:IPR036156|rcsb pdb:1DP0|rcsb pdb:1F4A|rcsb pdb:1F4H|rcsb pdb:1HN1|rcsb pdb:1JYN|rcsb pdb:1JYV|rcsb pdb:1JYW|rcsb pdb:1JYX|rcsb pdb:1JZ2|rcsb pdb:1JZ3|rcsb pdb:1JZ4|rcsb pdb:1JZ5|rcsb pdb:1JZ6|rcsb pdb:1JZ7|rcsb pdb:1JZ8|rcsb pdb:1PX3|rcsb pdb:1PX4|rcsb pdb:3CZJ|rcsb pdb:3DYM|rcsb pdb:3DYO|rcsb pdb:3DYP|rcsb pdb:3E1F|rcsb pdb:3I3B|rcsb pdb:3I3D|rcsb pdb:3I3E|rcsb pdb:3IAP|rcsb pdb:6DRV|rcsb pdb:6KUZ|rcsb pdb:6TSH|rcsb pdb:6TSK|rcsb pdb:6TTE|rcsb pdb:6X1Q|rcsb pdb:7BRS|rcsb pdb:7BTK|rcsb pdb:3IAQ|rcsb pdb:3J7H|rcsb pdb:3MUY|rcsb pdb:3MUZ|rcsb pdb:3MV0|rcsb pdb:3MV1|rcsb pdb:3SEP|rcsb pdb:3T08|rcsb pdb:3T09|rcsb pdb:3T0A|rcsb pdb:3T0B|rcsb pdb:3T0D|rcsb pdb:3T2O|rcsb pdb:3T2P|rcsb pdb:3T2Q|rcsb pdb:3VD3|rcsb pdb:3VD4|rcsb pdb:3VD5|rcsb pdb:3VD7|rcsb pdb:3VD9|rcsb pdb:3VDA|rcsb pdb:3VDB|rcsb pdb:3VDC|rcsb pdb:4CKD|rcsb pdb:4DUV|rcsb pdb:4DUW|rcsb pdb:4DUX|rcsb pdb:4TTG|rcsb pdb:4V40|rcsb pdb:4V41|rcsb pdb:4V44|rcsb pdb:4V45|rcsb pdb:5A1A|rcsb pdb:6CVM|refseq:WP_000177906.1|refseq:NP_414878.1|dip:DIP-10081N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:qCyxQe9x+jw8S7wbG6aJYE6UieI83333 rogid:qCyxQe9x+jw8S7wbG6aJYE6UieI83333 rigid:x98NBVsIg7UplpSKS74RRhn3TNQ false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A2K1 uniprotkb:P0A2K1 intact:EBI-1028431|uniprotkb:P00933|uniprotkb:Q56141|ensemblbacteria:AAL20644 intact:EBI-1028431|uniprotkb:P00933|uniprotkb:Q56141|ensemblbacteria:AAL20644 psi-mi:trpb_salty(display_long)|uniprotkb:trpB(gene name)|psi-mi:trpB(display_short)|uniprotkb:STM1726(locus name) psi-mi:trpb_salty(display_long)|uniprotkb:trpB(gene name)|psi-mi:trpB(display_short)|uniprotkb:STM1726(locus name) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:99287(salty)|taxid:99287(Salmonella typhimurium) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064359|imex:IM-21554-3|dip:DIP-189641E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_460685.1|ensemblbacteria:AAL20644(transcript)|ensemblbacteria:STM1726(gene)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004834"(tryptophan synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR023026|interpro:IPR036052|rcsb pdb:1A50|rcsb pdb:1A5A|rcsb pdb:1A5B|rcsb pdb:1A5S|rcsb pdb:1BEU|rcsb pdb:1BKS|rcsb pdb:1C29|rcsb pdb:1C8V|rcsb pdb:1C9D|rcsb pdb:1CW2|rcsb pdb:1CX9|rcsb pdb:1FUY|rcsb pdb:1K3U|rcsb pdb:1K7E|rcsb pdb:1K7F|rcsb pdb:1K7X|rcsb pdb:1K8X|rcsb pdb:1K8Y|rcsb pdb:1K8Z|rcsb pdb:1KFB|rcsb pdb:1KFC|rcsb pdb:1KFE|rcsb pdb:1KFJ|rcsb pdb:1KFK|rcsb pdb:1QOP|rcsb pdb:1QOQ|rcsb pdb:1TJP|rcsb pdb:1TTP|rcsb pdb:1TTQ|rcsb pdb:1UBS|rcsb pdb:1WBJ|rcsb pdb:2CLE|rcsb pdb:2CLF|rcsb pdb:2CLH|rcsb pdb:2CLI|rcsb pdb:2CLK|rcsb pdb:2CLL|rcsb pdb:2CLM|rcsb pdb:2CLO|rcsb pdb:2J9X|rcsb pdb:2J9Y|rcsb pdb:2J9Z|rcsb pdb:2RH9|rcsb pdb:2RHG|rcsb pdb:2TRS|rcsb pdb:2TSY|rcsb pdb:2TYS|rcsb pdb:2WSY|rcsb pdb:3CEP|rcsb pdb:3PR2|rcsb pdb:4HN4|rcsb pdb:4HPJ|rcsb pdb:4HPX|rcsb pdb:4HT3|rcsb pdb:4KKX|rcsb pdb:4WX2|rcsb pdb:4XUG|rcsb pdb:4Y6G|rcsb pdb:4ZQC|rcsb pdb:5BW6|rcsb pdb:5CGQ|rcsb pdb:6C73|rcsb pdb:6D0V|rcsb pdb:6DUC|rcsb pdb:6DZ4|rcsb pdb:6DZO|rcsb pdb:6O1H|rcsb pdb:6VFD|rcsb pdb:6VNT|rcsb pdb:6WDU|rcsb pdb:6WX3|rcsb pdb:6X0C|rcsb pdb:6XE3|rcsb pdb:6XIN|rcsb pdb:6XNC|rcsb pdb:6XOY|rcsb pdb:6XRH|rcsb pdb:6XT0|refseq:WP_000209485.1|dip:DIP-35707N refseq:NP_460685.1|ensemblbacteria:AAL20644(transcript)|ensemblbacteria:STM1726(gene)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004834"(tryptophan synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR023026|interpro:IPR036052|rcsb pdb:1A50|rcsb pdb:1A5A|rcsb pdb:1A5B|rcsb pdb:1A5S|rcsb pdb:1BEU|rcsb pdb:1BKS|rcsb pdb:1C29|rcsb pdb:1C8V|rcsb pdb:1C9D|rcsb pdb:1CW2|rcsb pdb:1CX9|rcsb pdb:1FUY|rcsb pdb:1K3U|rcsb pdb:1K7E|rcsb pdb:1K7F|rcsb pdb:1K7X|rcsb pdb:1K8X|rcsb pdb:1K8Y|rcsb pdb:1K8Z|rcsb pdb:1KFB|rcsb pdb:1KFC|rcsb pdb:1KFE|rcsb pdb:1KFJ|rcsb pdb:1KFK|rcsb pdb:1QOP|rcsb pdb:1QOQ|rcsb pdb:1TJP|rcsb pdb:1TTP|rcsb pdb:1TTQ|rcsb pdb:1UBS|rcsb pdb:1WBJ|rcsb pdb:2CLE|rcsb pdb:2CLF|rcsb pdb:2CLH|rcsb pdb:2CLI|rcsb pdb:2CLK|rcsb pdb:2CLL|rcsb pdb:2CLM|rcsb pdb:2CLO|rcsb pdb:2J9X|rcsb pdb:2J9Y|rcsb pdb:2J9Z|rcsb pdb:2RH9|rcsb pdb:2RHG|rcsb pdb:2TRS|rcsb pdb:2TSY|rcsb pdb:2TYS|rcsb pdb:2WSY|rcsb pdb:3CEP|rcsb pdb:3PR2|rcsb pdb:4HN4|rcsb pdb:4HPJ|rcsb pdb:4HPX|rcsb pdb:4HT3|rcsb pdb:4KKX|rcsb pdb:4WX2|rcsb pdb:4XUG|rcsb pdb:4Y6G|rcsb pdb:4ZQC|rcsb pdb:5BW6|rcsb pdb:5CGQ|rcsb pdb:6C73|rcsb pdb:6D0V|rcsb pdb:6DUC|rcsb pdb:6DZ4|rcsb pdb:6DZO|rcsb pdb:6O1H|rcsb pdb:6VFD|rcsb pdb:6VNT|rcsb pdb:6WDU|rcsb pdb:6WX3|rcsb pdb:6X0C|rcsb pdb:6XE3|rcsb pdb:6XIN|rcsb pdb:6XNC|rcsb pdb:6XOY|rcsb pdb:6XRH|rcsb pdb:6XT0|refseq:WP_000209485.1|dip:DIP-35707N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zPCoRC2efpWAdh4WwPAZkY1lo3M99287 rogid:zPCoRC2efpWAdh4WwPAZkY1lo3M99287 rigid:Nqyw60gu2u0Fxtdj8tlHMmUSfOA false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02743 uniprotkb:P02743 intact:EBI-2115799|ensembl:ENSP00000255040 intact:EBI-2115799|ensembl:ENSP00000255040 psi-mi:samp_human(display_long)|uniprotkb:APCS(gene name)|psi-mi:APCS(display_short)|uniprotkb:PTX2(gene name synonym)|uniprotkb:9.5S alpha-1-glycoprotein(gene name synonym) psi-mi:samp_human(display_long)|uniprotkb:APCS(gene name)|psi-mi:APCS(display_short)|uniprotkb:PTX2(gene name synonym)|uniprotkb:9.5S alpha-1-glycoprotein(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064343|imex:IM-21554-2|dip:DIP-191943E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001630.1|dip:DIP-46911N|ensembl:ENSG00000132703(gene)|ensembl:ENST00000255040(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006457"(protein folding)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0044869"(negative regulation by host of viral exo-alpha-sialidase activity)|go:"GO:0044871"(negative regulation by host of viral glycoprotein metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1903016"(negative regulation of exo-alpha-sialidase activity)|go:"GO:1903019"(negative regulation of glycoprotein metabolic process)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|rcsb pdb:1GYK|rcsb pdb:1LGN|rcsb pdb:1SAC|rcsb pdb:2A3W|rcsb pdb:2A3X|rcsb pdb:2A3Y|rcsb pdb:2W08|rcsb pdb:3D5O|rcsb pdb:3KQR|rcsb pdb:4AVS|rcsb pdb:4AVT|rcsb pdb:4AVV|rcsb pdb:4AYU|reactome:R-HSA-977225 refseq:NP_001630.1|dip:DIP-46911N|ensembl:ENSG00000132703(gene)|ensembl:ENST00000255040(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006457"(protein folding)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0044869"(negative regulation by host of viral exo-alpha-sialidase activity)|go:"GO:0044871"(negative regulation by host of viral glycoprotein metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1903016"(negative regulation of exo-alpha-sialidase activity)|go:"GO:1903019"(negative regulation of glycoprotein metabolic process)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|rcsb pdb:1GYK|rcsb pdb:1LGN|rcsb pdb:1SAC|rcsb pdb:2A3W|rcsb pdb:2A3X|rcsb pdb:2A3Y|rcsb pdb:2W08|rcsb pdb:3D5O|rcsb pdb:3KQR|rcsb pdb:4AVS|rcsb pdb:4AVT|rcsb pdb:4AVV|rcsb pdb:4AYU|reactome:R-HSA-977225 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:WOzyPFzTtaBN2E4vVhJyXLGNLcY9606 rogid:WOzyPFzTtaBN2E4vVhJyXLGNLcY9606 rigid:oeTn64Xk58ZfLOsmi+mXLlLSPNA false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02766 uniprotkb:P02766 intact:EBI-711909|ensembl:ENSP00000237014|ensembl:ENSP00000497927|uniprotkb:Q6IB96|uniprotkb:Q9UBZ6|uniprotkb:Q9UCM9|uniprotkb:Q549C7 intact:EBI-711909|ensembl:ENSP00000237014|ensembl:ENSP00000497927|uniprotkb:Q6IB96|uniprotkb:Q9UBZ6|uniprotkb:Q9UCM9|uniprotkb:Q549C7 psi-mi:tthy_human(display_long)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym)|uniprotkb:ATTR(gene name synonym)|uniprotkb:TTR(gene name)|psi-mi:TTR(display_short)|uniprotkb:PALB(gene name synonym) psi-mi:tthy_human(display_long)|uniprotkb:Prealbumin(gene name synonym)|uniprotkb:TBPA(gene name synonym)|uniprotkb:ATTR(gene name synonym)|uniprotkb:TTR(gene name)|psi-mi:TTR(display_short)|uniprotkb:PALB(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064391|imex:IM-21554-5|dip:DIP-74833E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3GLZ|rcsb pdb:3GPS|rcsb pdb:3GRB|rcsb pdb:3GRG|rcsb pdb:3GS0|rcsb pdb:3GS4|rcsb pdb:3GS7|rcsb pdb:3HJ0|rcsb pdb:3I9A|rcsb pdb:3I9I|rcsb pdb:3I9P|rcsb pdb:3IMR|rcsb pdb:3IMS|rcsb pdb:3IMT|rcsb pdb:3IMU|rcsb pdb:3IMV|rcsb pdb:3IMW|rcsb pdb:3IPB|rcsb pdb:3IPE|rcsb pdb:3KGS|rcsb pdb:3KGT|rcsb pdb:3KGU|rcsb pdb:3M1O|rcsb pdb:3NEE|rcsb pdb:3NEO|rcsb pdb:3NES|rcsb pdb:3NEX|rcsb pdb:3NG5|rcsb pdb:3OZK|rcsb pdb:3OZL|rcsb pdb:3FCB|rcsb pdb:3P3R|rcsb pdb:3P3S|rcsb pdb:3P3T|rcsb pdb:3P3U|rcsb pdb:3SSG|rcsb pdb:3TCT|rcsb pdb:3TFB|rcsb pdb:3U2I|rcsb pdb:3U2J|rcsb pdb:3W3B|rcsb pdb:4ABQ|rcsb pdb:4ABU|rcsb pdb:4ABV|rcsb pdb:4ABW|rcsb pdb:4AC2|rcsb pdb:4AC4|rcsb pdb:4ACT|rcsb pdb:4ANK|rcsb pdb:4D7B|rcsb pdb:4DER|rcsb pdb:4DES|rcsb pdb:4DET|rcsb pdb:4DEU|rcsb pdb:4DEW|rcsb pdb:4FI6|rcsb pdb:4FI7|rcsb pdb:4FI8|rcsb pdb:4HIQ|rcsb pdb:4HIS|rcsb pdb:4HJS|rcsb pdb:4HJT|rcsb pdb:4HJU|rcsb pdb:4I85|rcsb pdb:4I87|rcsb pdb:4IIZ|rcsb pdb:4IK6|rcsb pdb:4IK7|rcsb pdb:4IKI|rcsb pdb:4IKJ|rcsb pdb:4IKK|rcsb pdb:4IKL|rcsb pdb:4KY2|rcsb pdb:4L1S|rcsb pdb:4L1T|rcsb pdb:4MAS|rcsb pdb:4MRB|rcsb pdb:4MRC|rcsb pdb:4N85|rcsb pdb:4N86|rcsb pdb:4N87|rcsb pdb:4PM1|rcsb pdb:4PME|rcsb pdb:4PMF|rcsb pdb:4PVL|rcsb pdb:4PVM|rcsb pdb:4PVN|rcsb pdb:4I89|rcsb pdb:4PWE|rcsb pdb:4PWF|rcsb pdb:4PWG|rcsb pdb:4TLK|rcsb pdb:4TLS|rcsb pdb:4TLT|rcsb pdb:4TLU|rcsb pdb:4TM9|rcsb pdb:4TNE|rcsb pdb:4PWH|rcsb pdb:4TNF|rcsb pdb:4TNG|rcsb pdb:4TQ8|rcsb pdb:4TQH|rcsb pdb:4TQI|rcsb pdb:4TQP|rcsb pdb:4PWI|rcsb pdb:4PWJ|rcsb pdb:4PWK|rcsb pdb:4QRF|rcsb pdb:4WNJ|rcsb pdb:4WNS|rcsb pdb:4QXV|rcsb pdb:4QYA|rcsb pdb:4WO0|rcsb pdb:4TKW|rcsb pdb:4TL4|rcsb pdb:4TL5|rcsb pdb:4Y9B|rcsb pdb:4Y9C|rcsb pdb:4Y9E|rcsb pdb:4Y9F|rcsb pdb:4Y9G|rcsb pdb:4YDM|rcsb pdb:4YDN|rcsb pdb:5A6I|rcsb pdb:5AKS|rcsb pdb:5AKT|rcsb pdb:5AKV|rcsb pdb:5AL0|rcsb pdb:5AYT|rcsb pdb:5BOJ|rcsb pdb:5CLX|rcsb pdb:5CLY|rcsb pdb:5CLZ|rcsb pdb:5CM1|rcsb pdb:5AL8|rcsb pdb:5CN3|rcsb pdb:5CNH|rcsb pdb:5CR1|rcsb pdb:5DEJ|rcsb pdb:5DWP|rcsb pdb:5E23|rcsb pdb:5E4A|rcsb pdb:5E4O|rcsb pdb:5EN3|rcsb pdb:5EZP|rcsb pdb:5FO2|rcsb pdb:5FW6|rcsb pdb:5FW7|rcsb pdb:5FW8|rcsb pdb:5H0V|rcsb pdb:5H0W|rcsb pdb:5H0X|rcsb pdb:5H0Y|rcsb pdb:5H0Z|rcsb pdb:5HJG|rcsb pdb:5IHH|rcsb pdb:5JID|rcsb pdb:5JIM|rcsb pdb:5JIQ|rcsb pdb:5K1J|rcsb pdb:5K1N|rcsb pdb:5L4F|rcsb pdb:5L4I|rcsb pdb:5L4M|rcsb pdb:5LLL|rcsb pdb:5LLV|rcsb pdb:5N5Q|rcsb pdb:5N62|rcsb pdb:5N7C|rcsb pdb:5NFE|rcsb pdb:5NFW|rcsb pdb:5OQ0|rcsb pdb:5TTR|rcsb pdb:5TZL|rcsb pdb:5U48|rcsb pdb:5U49|rcsb pdb:5U4A|rcsb pdb:5U4B|rcsb pdb:5U4C|rcsb pdb:5U4D|rcsb pdb:5U4E|rcsb pdb:5U4F|rcsb pdb:5U4G|rcsb pdb:6D0W|rcsb pdb:6E6Z|rcsb pdb:6E70|rcsb pdb:6E71|rcsb pdb:5L4J|rcsb pdb:6E72|rcsb pdb:6E73|rcsb pdb:6E74|rcsb pdb:6E75|rcsb pdb:6E76|rcsb pdb:6E77|rcsb pdb:6E78|rcsb pdb:6EP1|rcsb pdb:6FFT|rcsb pdb:6FWD|rcsb pdb:6FXU|rcsb pdb:6FZL|rcsb pdb:6GR7|rcsb pdb:6GRP|rcsb pdb:6IMX|rcsb pdb:6IMY|rcsb pdb:6KGB|rcsb pdb:6R66|rcsb pdb:6R67|rcsb pdb:6R68|rcsb pdb:6R6I|rcsb pdb:6SDZ|rcsb pdb:6SUG|rcsb pdb:6SUH|rcsb pdb:6TI9|rcsb pdb:6TJN|rcsb pdb:6TXV|rcsb pdb:6TXW|rcsb pdb:6U0Q|rcsb pdb:6XTK|rcsb pdb:7ACU|reactome:R-HSA-2453864|reactome:R-HSA-2453902|reactome:R-HSA-3000171|reactome:R-HSA-6798695|reactome:R-HSA-975634|reactome:R-HSA-977225|ensembl:ENST00000237014(transcript)|ensembl:ENST00000649620(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P02766|rcsb pdb:1BM7|rcsb pdb:1BMZ|rcsb pdb:1BZ8|rcsb pdb:1BZD|rcsb pdb:1BZE|rcsb pdb:1DVQ|rcsb pdb:1DVS|rcsb pdb:1DVT|rcsb pdb:1DVU|rcsb pdb:1DVX|rcsb pdb:1DVY|rcsb pdb:1DVZ|rcsb pdb:1E3F|rcsb pdb:1E4H|ensembl:ENSG00000118271(gene)|rcsb pdb:1E5A|rcsb pdb:1ETA|rcsb pdb:1ETB|rcsb pdb:1F41|rcsb pdb:1F64|rcsb pdb:1F86|rcsb pdb:1FH2|rcsb pdb:1FHN|rcsb pdb:1G1O|rcsb pdb:1GKO|rcsb pdb:1ICT|rcsb pdb:1III|rcsb pdb:1IIK|rcsb pdb:1IJN|rcsb pdb:1QAB|rcsb pdb:1QWH|rcsb pdb:1RLB|rcsb pdb:1SOK|rcsb pdb:1SOQ|rcsb pdb:1THA|rcsb pdb:1THC|rcsb pdb:1TLM|rcsb pdb:1TSH|rcsb pdb:1TT6|rcsb pdb:1TTA|rcsb pdb:1TTB|rcsb pdb:2F7I|rcsb pdb:2F8I|rcsb pdb:2FBR|rcsb pdb:2FLM|rcsb pdb:1TTC|rcsb pdb:2G3X|rcsb pdb:2G3Z|rcsb pdb:2G4E|rcsb pdb:2G4G|rcsb pdb:2G5U|rcsb pdb:2G9K|rcsb pdb:2GAB|rcsb pdb:2H4E|rcsb pdb:2M5N|rcsb pdb:2NBO|rcsb pdb:2NBP|rcsb pdb:2NOY|rcsb pdb:2PAB|rcsb pdb:2QEL|rcsb pdb:2QGB|rcsb pdb:2QGC|rcsb pdb:2QGD|rcsb pdb:1TTR|rcsb pdb:1TYR|rcsb pdb:1TZ8|rcsb pdb:1U21|rcsb pdb:2QGE|rcsb pdb:2ROX|rcsb pdb:2ROY|rcsb pdb:2TRH|rcsb pdb:2TRY|rcsb pdb:2WQA|rcsb pdb:3A4D|rcsb pdb:3A4E|rcsb pdb:3A4F|rcsb pdb:3B56|rcsb pdb:3BSZ|rcsb pdb:3BT0|rcsb pdb:3CBR|rcsb pdb:3CFM|rcsb pdb:3CFN|rcsb pdb:1X7S|rcsb pdb:1X7T|rcsb pdb:3CFQ|rcsb pdb:3CFT|rcsb pdb:3CN0|rcsb pdb:3CN1|rcsb pdb:3CN2|rcsb pdb:3CN3|rcsb pdb:3CN4|rcsb pdb:3CXF|rcsb pdb:3D2T|rcsb pdb:3D7P|rcsb pdb:3DGD|rcsb pdb:3DID|rcsb pdb:1Y1D|rcsb pdb:1Z7J|rcsb pdb:1ZCR|rcsb pdb:1ZD6|rcsb pdb:2B14|rcsb pdb:2B15|rcsb pdb:2B16|rcsb pdb:2B77|rcsb pdb:2B9A|rcsb pdb:3DJR|rcsb pdb:3DJS|rcsb pdb:3DJT|rcsb pdb:3DJZ|rcsb pdb:3DK0|rcsb pdb:3DK2|rcsb pdb:3DO4|rcsb pdb:3ESN|rcsb pdb:3ESO|rcsb pdb:3ESP|rcsb pdb:3FC8|refseq:NP_000362.1|dip:DIP-1083N rcsb pdb:3GLZ|rcsb pdb:3GPS|rcsb pdb:3GRB|rcsb pdb:3GRG|rcsb pdb:3GS0|rcsb pdb:3GS4|rcsb pdb:3GS7|rcsb pdb:3HJ0|rcsb pdb:3I9A|rcsb pdb:3I9I|rcsb pdb:3I9P|rcsb pdb:3IMR|rcsb pdb:3IMS|rcsb pdb:3IMT|rcsb pdb:3IMU|rcsb pdb:3IMV|rcsb pdb:3IMW|rcsb pdb:3IPB|rcsb pdb:3IPE|rcsb pdb:3KGS|rcsb pdb:3KGT|rcsb pdb:3KGU|rcsb pdb:3M1O|rcsb pdb:3NEE|rcsb pdb:3NEO|rcsb pdb:3NES|rcsb pdb:3NEX|rcsb pdb:3NG5|rcsb pdb:3OZK|rcsb pdb:3OZL|rcsb pdb:3FCB|rcsb pdb:3P3R|rcsb pdb:3P3S|rcsb pdb:3P3T|rcsb pdb:3P3U|rcsb pdb:3SSG|rcsb pdb:3TCT|rcsb pdb:3TFB|rcsb pdb:3U2I|rcsb pdb:3U2J|rcsb pdb:3W3B|rcsb pdb:4ABQ|rcsb pdb:4ABU|rcsb pdb:4ABV|rcsb pdb:4ABW|rcsb pdb:4AC2|rcsb pdb:4AC4|rcsb pdb:4ACT|rcsb pdb:4ANK|rcsb pdb:4D7B|rcsb pdb:4DER|rcsb pdb:4DES|rcsb pdb:4DET|rcsb pdb:4DEU|rcsb pdb:4DEW|rcsb pdb:4FI6|rcsb pdb:4FI7|rcsb pdb:4FI8|rcsb pdb:4HIQ|rcsb pdb:4HIS|rcsb pdb:4HJS|rcsb pdb:4HJT|rcsb pdb:4HJU|rcsb pdb:4I85|rcsb pdb:4I87|rcsb pdb:4IIZ|rcsb pdb:4IK6|rcsb pdb:4IK7|rcsb pdb:4IKI|rcsb pdb:4IKJ|rcsb pdb:4IKK|rcsb pdb:4IKL|rcsb pdb:4KY2|rcsb pdb:4L1S|rcsb pdb:4L1T|rcsb pdb:4MAS|rcsb pdb:4MRB|rcsb pdb:4MRC|rcsb pdb:4N85|rcsb pdb:4N86|rcsb pdb:4N87|rcsb pdb:4PM1|rcsb pdb:4PME|rcsb pdb:4PMF|rcsb pdb:4PVL|rcsb pdb:4PVM|rcsb pdb:4PVN|rcsb pdb:4I89|rcsb pdb:4PWE|rcsb pdb:4PWF|rcsb pdb:4PWG|rcsb pdb:4TLK|rcsb pdb:4TLS|rcsb pdb:4TLT|rcsb pdb:4TLU|rcsb pdb:4TM9|rcsb pdb:4TNE|rcsb pdb:4PWH|rcsb pdb:4TNF|rcsb pdb:4TNG|rcsb pdb:4TQ8|rcsb pdb:4TQH|rcsb pdb:4TQI|rcsb pdb:4TQP|rcsb pdb:4PWI|rcsb pdb:4PWJ|rcsb pdb:4PWK|rcsb pdb:4QRF|rcsb pdb:4WNJ|rcsb pdb:4WNS|rcsb pdb:4QXV|rcsb pdb:4QYA|rcsb pdb:4WO0|rcsb pdb:4TKW|rcsb pdb:4TL4|rcsb pdb:4TL5|rcsb pdb:4Y9B|rcsb pdb:4Y9C|rcsb pdb:4Y9E|rcsb pdb:4Y9F|rcsb pdb:4Y9G|rcsb pdb:4YDM|rcsb pdb:4YDN|rcsb pdb:5A6I|rcsb pdb:5AKS|rcsb pdb:5AKT|rcsb pdb:5AKV|rcsb pdb:5AL0|rcsb pdb:5AYT|rcsb pdb:5BOJ|rcsb pdb:5CLX|rcsb pdb:5CLY|rcsb pdb:5CLZ|rcsb pdb:5CM1|rcsb pdb:5AL8|rcsb pdb:5CN3|rcsb pdb:5CNH|rcsb pdb:5CR1|rcsb pdb:5DEJ|rcsb pdb:5DWP|rcsb pdb:5E23|rcsb pdb:5E4A|rcsb pdb:5E4O|rcsb pdb:5EN3|rcsb pdb:5EZP|rcsb pdb:5FO2|rcsb pdb:5FW6|rcsb pdb:5FW7|rcsb pdb:5FW8|rcsb pdb:5H0V|rcsb pdb:5H0W|rcsb pdb:5H0X|rcsb pdb:5H0Y|rcsb pdb:5H0Z|rcsb pdb:5HJG|rcsb pdb:5IHH|rcsb pdb:5JID|rcsb pdb:5JIM|rcsb pdb:5JIQ|rcsb pdb:5K1J|rcsb pdb:5K1N|rcsb pdb:5L4F|rcsb pdb:5L4I|rcsb pdb:5L4M|rcsb pdb:5LLL|rcsb pdb:5LLV|rcsb pdb:5N5Q|rcsb pdb:5N62|rcsb pdb:5N7C|rcsb pdb:5NFE|rcsb pdb:5NFW|rcsb pdb:5OQ0|rcsb pdb:5TTR|rcsb pdb:5TZL|rcsb pdb:5U48|rcsb pdb:5U49|rcsb pdb:5U4A|rcsb pdb:5U4B|rcsb pdb:5U4C|rcsb pdb:5U4D|rcsb pdb:5U4E|rcsb pdb:5U4F|rcsb pdb:5U4G|rcsb pdb:6D0W|rcsb pdb:6E6Z|rcsb pdb:6E70|rcsb pdb:6E71|rcsb pdb:5L4J|rcsb pdb:6E72|rcsb pdb:6E73|rcsb pdb:6E74|rcsb pdb:6E75|rcsb pdb:6E76|rcsb pdb:6E77|rcsb pdb:6E78|rcsb pdb:6EP1|rcsb pdb:6FFT|rcsb pdb:6FWD|rcsb pdb:6FXU|rcsb pdb:6FZL|rcsb pdb:6GR7|rcsb pdb:6GRP|rcsb pdb:6IMX|rcsb pdb:6IMY|rcsb pdb:6KGB|rcsb pdb:6R66|rcsb pdb:6R67|rcsb pdb:6R68|rcsb pdb:6R6I|rcsb pdb:6SDZ|rcsb pdb:6SUG|rcsb pdb:6SUH|rcsb pdb:6TI9|rcsb pdb:6TJN|rcsb pdb:6TXV|rcsb pdb:6TXW|rcsb pdb:6U0Q|rcsb pdb:6XTK|rcsb pdb:7ACU|reactome:R-HSA-2453864|reactome:R-HSA-2453902|reactome:R-HSA-3000171|reactome:R-HSA-6798695|reactome:R-HSA-975634|reactome:R-HSA-977225|ensembl:ENST00000237014(transcript)|ensembl:ENST00000649620(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|interpro:IPR000895(Transthyretin)|interpro:IPR023416|interpro:IPR023418|interpro:IPR023419|interpro:IPR030178|interpro:IPR036817|mint:P02766|rcsb pdb:1BM7|rcsb pdb:1BMZ|rcsb pdb:1BZ8|rcsb pdb:1BZD|rcsb pdb:1BZE|rcsb pdb:1DVQ|rcsb pdb:1DVS|rcsb pdb:1DVT|rcsb pdb:1DVU|rcsb pdb:1DVX|rcsb pdb:1DVY|rcsb pdb:1DVZ|rcsb pdb:1E3F|rcsb pdb:1E4H|ensembl:ENSG00000118271(gene)|rcsb pdb:1E5A|rcsb pdb:1ETA|rcsb pdb:1ETB|rcsb pdb:1F41|rcsb pdb:1F64|rcsb pdb:1F86|rcsb pdb:1FH2|rcsb pdb:1FHN|rcsb pdb:1G1O|rcsb pdb:1GKO|rcsb pdb:1ICT|rcsb pdb:1III|rcsb pdb:1IIK|rcsb pdb:1IJN|rcsb pdb:1QAB|rcsb pdb:1QWH|rcsb pdb:1RLB|rcsb pdb:1SOK|rcsb pdb:1SOQ|rcsb pdb:1THA|rcsb pdb:1THC|rcsb pdb:1TLM|rcsb pdb:1TSH|rcsb pdb:1TT6|rcsb pdb:1TTA|rcsb pdb:1TTB|rcsb pdb:2F7I|rcsb pdb:2F8I|rcsb pdb:2FBR|rcsb pdb:2FLM|rcsb pdb:1TTC|rcsb pdb:2G3X|rcsb pdb:2G3Z|rcsb pdb:2G4E|rcsb pdb:2G4G|rcsb pdb:2G5U|rcsb pdb:2G9K|rcsb pdb:2GAB|rcsb pdb:2H4E|rcsb pdb:2M5N|rcsb pdb:2NBO|rcsb pdb:2NBP|rcsb pdb:2NOY|rcsb pdb:2PAB|rcsb pdb:2QEL|rcsb pdb:2QGB|rcsb pdb:2QGC|rcsb pdb:2QGD|rcsb pdb:1TTR|rcsb pdb:1TYR|rcsb pdb:1TZ8|rcsb pdb:1U21|rcsb pdb:2QGE|rcsb pdb:2ROX|rcsb pdb:2ROY|rcsb pdb:2TRH|rcsb pdb:2TRY|rcsb pdb:2WQA|rcsb pdb:3A4D|rcsb pdb:3A4E|rcsb pdb:3A4F|rcsb pdb:3B56|rcsb pdb:3BSZ|rcsb pdb:3BT0|rcsb pdb:3CBR|rcsb pdb:3CFM|rcsb pdb:3CFN|rcsb pdb:1X7S|rcsb pdb:1X7T|rcsb pdb:3CFQ|rcsb pdb:3CFT|rcsb pdb:3CN0|rcsb pdb:3CN1|rcsb pdb:3CN2|rcsb pdb:3CN3|rcsb pdb:3CN4|rcsb pdb:3CXF|rcsb pdb:3D2T|rcsb pdb:3D7P|rcsb pdb:3DGD|rcsb pdb:3DID|rcsb pdb:1Y1D|rcsb pdb:1Z7J|rcsb pdb:1ZCR|rcsb pdb:1ZD6|rcsb pdb:2B14|rcsb pdb:2B15|rcsb pdb:2B16|rcsb pdb:2B77|rcsb pdb:2B9A|rcsb pdb:3DJR|rcsb pdb:3DJS|rcsb pdb:3DJT|rcsb pdb:3DJZ|rcsb pdb:3DK0|rcsb pdb:3DK2|rcsb pdb:3DO4|rcsb pdb:3ESN|rcsb pdb:3ESO|rcsb pdb:3ESP|rcsb pdb:3FC8|refseq:NP_000362.1|dip:DIP-1083N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:VwPs2NgicC89f7Ehgf4d6uE9DuU9606 rogid:VwPs2NgicC89f7Ehgf4d6uE9DuU9606 rigid:b7CRHsuCo54efsbeRS6UcjgPE5w false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8RTL3 uniprotkb:Q8RTL4 intact:EBI-1042214 intact:EBI-1042204 psi-mi:q8rtl3_9burk(display_long)|uniprotkb:nbzAd(gene name)|psi-mi:nbzAd(display_short) psi-mi:q8rtl4_9burk(display_long)|uniprotkb:nbzAc(gene name)|psi-mi:nbzAc(display_short) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:58226(comsp)|taxid:58226(Comamonas sp. JS765) taxid:58226(comsp)|taxid:58226(Comamonas sp. JS765) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064407|imex:IM-21554-6|dip:DIP-79486E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR000391(Aromatic-ring-hydroxylating dioxygenase, beta subunit)|interpro:IPR032710|rcsb pdb:2BMO|rcsb pdb:2BMQ|rcsb pdb:2BMR|dip:DIP-45325N rcsb pdb:2BMR|go:"GO:0005506"(iron ion binding)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR001663(Aromatic-ring-hydroxylating dioxygenase, alpha subunit)|interpro:IPR015879(Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal)|interpro:IPR015881(Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site)|interpro:IPR017941|interpro:IPR036922|interpro:IPR043266|interpro:IPR044637|rcsb pdb:2BMO|rcsb pdb:2BMQ|dip:DIP-45324N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:gyPrBOCGCP0GLXKKiqX8Cofxe+Q58226 rogid:dq0gm5/k6JTrjdbpHzVrs3cAgJo58226 rigid:gA9WHzXGQtw0GS8yrh+tBlM50W8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22869 uniprotkb:P18798 intact:EBI-9023796|uniprotkb:Q609N8|ensemblbacteria:AAU92736 intact:EBI-9023802|uniprotkb:Q609N7|ensemblbacteria:AAU92727 psi-mi:mema_metca(display_long)|uniprotkb:mmoX(gene name)|psi-mi:mmoX(display_short)|uniprotkb:Methane hydroxylase(gene name synonym)|uniprotkb:MCA1194(locus name) psi-mi:memb_metca(display_long)|uniprotkb:mmoY(gene name)|psi-mi:mmoY(display_short)|uniprotkb:Methane hydroxylase(gene name synonym)|uniprotkb:MCA1195(locus name) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:243233(metca)|taxid:243233("Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)") taxid:243233(metca)|taxid:243233("Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064424|imex:IM-21554-7|dip:DIP-189638E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010960482.1|dip:DIP-59861N|ensemblbacteria:AAU92736(transcript)|ensemblbacteria:MCA1194(gene)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106317"(methane monooxygenase NADH activity)|go:"GO:0106318"(methane monooxygenase NADPH activity)|interpro:IPR003430(Methane/phenol/toluene hydroxylase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|rcsb pdb:1FYZ|rcsb pdb:1FZ0|rcsb pdb:1FZ1|rcsb pdb:1FZ2|rcsb pdb:1FZ3|rcsb pdb:1FZ4|rcsb pdb:1FZ5|rcsb pdb:1FZ6|rcsb pdb:1FZ7|rcsb pdb:1FZ8|rcsb pdb:1FZ9|rcsb pdb:1FZH|rcsb pdb:1FZI|rcsb pdb:1MMO|rcsb pdb:1MTY|rcsb pdb:1XMF|rcsb pdb:1XMG|rcsb pdb:1XMH|rcsb pdb:1XU3|rcsb pdb:1XU5|rcsb pdb:1XVB|rcsb pdb:1XVC|rcsb pdb:1XVD|rcsb pdb:1XVE|rcsb pdb:1XVF|rcsb pdb:1XVG|rcsb pdb:4GAM refseq:WP_010960483.1|dip:DIP-59862N|ensemblbacteria:AAU92727(transcript)|ensemblbacteria:MCA1195(gene)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0106317"(methane monooxygenase NADH activity)|go:"GO:0106318"(methane monooxygenase NADPH activity)|interpro:IPR003430(Methane/phenol/toluene hydroxylase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012078(Methane/phenol monooxygenase, hydroxylase component)|interpro:IPR012348(Ribonucleotide reductase-related)|rcsb pdb:1FYZ|rcsb pdb:1FZ0|rcsb pdb:1FZ1|rcsb pdb:1FZ2|rcsb pdb:1FZ3|rcsb pdb:1FZ4|rcsb pdb:1FZ5|rcsb pdb:1FZ6|rcsb pdb:1FZ7|rcsb pdb:1FZ8|rcsb pdb:1FZ9|rcsb pdb:1FZH|rcsb pdb:1FZI|rcsb pdb:1MMO|rcsb pdb:1MTY|rcsb pdb:1XMF|rcsb pdb:1XMG|rcsb pdb:1XMH|rcsb pdb:1XU3|rcsb pdb:1XU5|rcsb pdb:1XVB|rcsb pdb:1XVC|rcsb pdb:1XVD|rcsb pdb:1XVE|rcsb pdb:1XVF|rcsb pdb:1XVG|rcsb pdb:4GAM psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:243233(metca)|taxid:243233("Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)") - 2017/08/07 2017/08/10 rogid:jOkjW1KyWhUTK7XAz3XnSmMhUdY243233 rogid:gC++R31qdRTz37c4+1QsGLzqURI243233 rigid:u24bxeOLVJmSzw6V7hG+lMawuJg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22869 uniprotkb:P11987 intact:EBI-9023796|uniprotkb:Q609N8|ensemblbacteria:AAU92736 intact:EBI-9023811|uniprotkb:Q9RLQ5|uniprotkb:Q609N4|ensemblbacteria:AAU92724 psi-mi:mema_metca(display_long)|uniprotkb:mmoX(gene name)|psi-mi:mmoX(display_short)|uniprotkb:Methane hydroxylase(gene name synonym)|uniprotkb:MCA1194(locus name) psi-mi:memg_metca(display_long)|uniprotkb:mmoZ(gene name)|psi-mi:mmoZ(display_short)|uniprotkb:Methane hydroxylase(gene name synonym)|uniprotkb:MCA1198(locus name) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:243233(metca)|taxid:243233("Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)") taxid:243233(metca)|taxid:243233("Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064424|imex:IM-21554-7|dip:DIP-189638E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010960482.1|dip:DIP-59861N|ensemblbacteria:AAU92736(transcript)|ensemblbacteria:MCA1194(gene)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0106317"(methane monooxygenase NADH activity)|go:"GO:0106318"(methane monooxygenase NADPH activity)|interpro:IPR003430(Methane/phenol/toluene hydroxylase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|rcsb pdb:1FYZ|rcsb pdb:1FZ0|rcsb pdb:1FZ1|rcsb pdb:1FZ2|rcsb pdb:1FZ3|rcsb pdb:1FZ4|rcsb pdb:1FZ5|rcsb pdb:1FZ6|rcsb pdb:1FZ7|rcsb pdb:1FZ8|rcsb pdb:1FZ9|rcsb pdb:1FZH|rcsb pdb:1FZI|rcsb pdb:1MMO|rcsb pdb:1MTY|rcsb pdb:1XMF|rcsb pdb:1XMG|rcsb pdb:1XMH|rcsb pdb:1XU3|rcsb pdb:1XU5|rcsb pdb:1XVB|rcsb pdb:1XVC|rcsb pdb:1XVD|rcsb pdb:1XVE|rcsb pdb:1XVF|rcsb pdb:1XVG|rcsb pdb:4GAM refseq:WP_010960485.1|dip:DIP-59863N|ensemblbacteria:AAU92724(transcript)|ensemblbacteria:MCA1198(gene)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0015947"(methane metabolic process)|go:"GO:0106317"(methane monooxygenase NADH activity)|go:"GO:0106318"(methane monooxygenase NADPH activity)|interpro:IPR004222(Methane monooxygenase, gamma chain)|interpro:IPR015952(Methane monooxygenase, gamma chain, domain 1)|interpro:IPR015953(Methane monooxygenase, gamma chain, domain 2)|interpro:IPR036123|rcsb pdb:1FYZ|rcsb pdb:1FZ0|rcsb pdb:1FZ1|rcsb pdb:1FZ2|rcsb pdb:1FZ3|rcsb pdb:1FZ4|rcsb pdb:1FZ5|rcsb pdb:1FZ6|rcsb pdb:1FZ7|rcsb pdb:1FZ8|rcsb pdb:1FZ9|rcsb pdb:1FZH|rcsb pdb:1FZI|rcsb pdb:1MMO|rcsb pdb:1MTY|rcsb pdb:1XMF|rcsb pdb:1XMG|rcsb pdb:1XMH|rcsb pdb:1XU3|rcsb pdb:1XU5|rcsb pdb:1XVB|rcsb pdb:1XVC|rcsb pdb:1XVD|rcsb pdb:1XVE|rcsb pdb:1XVF|rcsb pdb:1XVG|rcsb pdb:4GAM psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:243233(metca)|taxid:243233("Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)") - 2017/08/07 2017/08/10 rogid:jOkjW1KyWhUTK7XAz3XnSmMhUdY243233 rogid:2IVhvhYTbnQoW800SkPD5NnvMZ0243233 rigid:u24bxeOLVJmSzw6V7hG+lMawuJg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00330 uniprotkb:P00330 intact:EBI-2218|uniprotkb:D6W1Y3|ensemblfungi:YOL086C intact:EBI-2218|uniprotkb:D6W1Y3|ensemblfungi:YOL086C psi-mi:adh1_yeast(display_long)|uniprotkb:ADH1(gene name)|psi-mi:ADH1(display_short)|uniprotkb:ADC1(gene name synonym)|uniprotkb:YOL086C(locus name)|uniprotkb:O0947(orf name)|uniprotkb:Alcohol dehydrogenase I(gene name synonym)|uniprotkb:YADH-1(gene name synonym) psi-mi:adh1_yeast(display_long)|uniprotkb:ADH1(gene name)|psi-mi:ADH1(display_short)|uniprotkb:ADC1(gene name synonym)|uniprotkb:YOL086C(locus name)|uniprotkb:O0947(orf name)|uniprotkb:Alcohol dehydrogenase I(gene name synonym)|uniprotkb:YADH-1(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064539|imex:IM-21554-11|dip:DIP-134550E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014555.1|sgd:S000005446|dip:DIP-1143N|mint:P00330|ensemblfungi:YOL086C(gene)|ensemblfungi:YOL086C_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006116"(NADH oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019170"("methylglyoxal reductase (NADH-dependent) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043458"(ethanol biosynthetic process involved in glucose fermentation to ethanol)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0046809"(replication compartment)|go:"GO:1904408"(melatonin binding)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|rcsb pdb:4W6Z|rcsb pdb:5ENV refseq:NP_014555.1|sgd:S000005446|dip:DIP-1143N|mint:P00330|ensemblfungi:YOL086C(gene)|ensemblfungi:YOL086C_mRNA(transcript)|go:"GO:0000947"(amino acid catabolic process to alcohol via Ehrlich pathway)|go:"GO:0004022"("alcohol dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006116"(NADH oxidation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019170"("methylglyoxal reductase (NADH-dependent) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043458"(ethanol biosynthetic process involved in glucose fermentation to ethanol)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0046809"(replication compartment)|go:"GO:1904408"(melatonin binding)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|rcsb pdb:4W6Z|rcsb pdb:5ENV psi-mi:"MI:0465"(dip) crc64:F14AE24B5D8D12A5 crc64:F14AE24B5D8D12A5 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:ud0TIPDwB9vm9Ug9a5a4wY20oZ8559292 rogid:ud0TIPDwB9vm9Ug9a5a4wY20oZ8559292 rigid:Fg4elJVNri68iH5f9CQjAumLKeg false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A2K1 uniprotkb:P00929 intact:EBI-1028431|uniprotkb:P00933|uniprotkb:Q56141|ensemblbacteria:AAL20644 intact:EBI-1028423|ensemblbacteria:AAL20645 psi-mi:trpb_salty(display_long)|uniprotkb:trpB(gene name)|psi-mi:trpB(display_short)|uniprotkb:STM1726(locus name) psi-mi:trpa_salty(display_long)|uniprotkb:trpA(gene name)|psi-mi:trpA(display_short)|uniprotkb:STM1727(locus name) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:99287(salty)|taxid:99287(Salmonella typhimurium) taxid:99287(salty)|taxid:99287(Salmonella typhimurium) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064522|imex:IM-21554-10|dip:DIP-64611E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_460685.1|ensemblbacteria:AAL20644(transcript)|ensemblbacteria:STM1726(gene)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004834"(tryptophan synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR023026|interpro:IPR036052|rcsb pdb:1A50|rcsb pdb:1A5A|rcsb pdb:1A5B|rcsb pdb:1A5S|rcsb pdb:1BEU|rcsb pdb:1BKS|rcsb pdb:1C29|rcsb pdb:1C8V|rcsb pdb:1C9D|rcsb pdb:1CW2|rcsb pdb:1CX9|rcsb pdb:1FUY|rcsb pdb:1K3U|rcsb pdb:1K7E|rcsb pdb:1K7F|rcsb pdb:1K7X|rcsb pdb:1K8X|rcsb pdb:1K8Y|rcsb pdb:1K8Z|rcsb pdb:1KFB|rcsb pdb:1KFC|rcsb pdb:1KFE|rcsb pdb:1KFJ|rcsb pdb:1KFK|rcsb pdb:1QOP|rcsb pdb:1QOQ|rcsb pdb:1TJP|rcsb pdb:1TTP|rcsb pdb:1TTQ|rcsb pdb:1UBS|rcsb pdb:1WBJ|rcsb pdb:2CLE|rcsb pdb:2CLF|rcsb pdb:2CLH|rcsb pdb:2CLI|rcsb pdb:2CLK|rcsb pdb:2CLL|rcsb pdb:2CLM|rcsb pdb:2CLO|rcsb pdb:2J9X|rcsb pdb:2J9Y|rcsb pdb:2J9Z|rcsb pdb:2RH9|rcsb pdb:2RHG|rcsb pdb:2TRS|rcsb pdb:2TSY|rcsb pdb:2TYS|rcsb pdb:2WSY|rcsb pdb:3CEP|rcsb pdb:3PR2|rcsb pdb:4HN4|rcsb pdb:4HPJ|rcsb pdb:4HPX|rcsb pdb:4HT3|rcsb pdb:4KKX|rcsb pdb:4WX2|rcsb pdb:4XUG|rcsb pdb:4Y6G|rcsb pdb:4ZQC|rcsb pdb:5BW6|rcsb pdb:5CGQ|rcsb pdb:6C73|rcsb pdb:6D0V|rcsb pdb:6DUC|rcsb pdb:6DZ4|rcsb pdb:6DZO|rcsb pdb:6O1H|rcsb pdb:6VFD|rcsb pdb:6VNT|rcsb pdb:6WDU|rcsb pdb:6WX3|rcsb pdb:6X0C|rcsb pdb:6XE3|rcsb pdb:6XIN|rcsb pdb:6XNC|rcsb pdb:6XOY|rcsb pdb:6XRH|rcsb pdb:6XT0|refseq:WP_000209485.1|dip:DIP-35707N refseq:NP_460686.1|ensemblbacteria:AAL20645(transcript)|ensemblbacteria:STM1727(gene)|go:"GO:0000162"(tryptophan biosynthetic process)|go:"GO:0004834"(tryptophan synthase activity)|go:"GO:0005829"(cytosol)|interpro:IPR002028(Tryptophan synthase, alpha chain)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018204|rcsb pdb:1A50|rcsb pdb:1A5A|rcsb pdb:1A5B|rcsb pdb:1A5S|rcsb pdb:1BEU|rcsb pdb:1BKS|rcsb pdb:1C29|rcsb pdb:1C8V|rcsb pdb:1C9D|rcsb pdb:1CW2|rcsb pdb:1CX9|rcsb pdb:1FUY|rcsb pdb:1K3U|rcsb pdb:1K7F|rcsb pdb:1K7X|rcsb pdb:1K8X|rcsb pdb:1K8Y|rcsb pdb:1K8Z|rcsb pdb:1KFB|rcsb pdb:1KFC|rcsb pdb:1KFE|rcsb pdb:1KFJ|rcsb pdb:1KFK|rcsb pdb:1QOP|rcsb pdb:1QOQ|rcsb pdb:1TJP|rcsb pdb:1TTP|rcsb pdb:1TTQ|rcsb pdb:1UBS|rcsb pdb:1WBJ|rcsb pdb:2CLE|rcsb pdb:2CLF|rcsb pdb:2CLH|rcsb pdb:2CLI|rcsb pdb:2CLK|rcsb pdb:2CLL|rcsb pdb:2CLM|rcsb pdb:2CLO|rcsb pdb:2J9X|rcsb pdb:2J9Y|rcsb pdb:2J9Z|rcsb pdb:2RH9|rcsb pdb:2RHG|rcsb pdb:2TRS|rcsb pdb:2TSY|rcsb pdb:2TYS|rcsb pdb:2WSY|rcsb pdb:3CEP|rcsb pdb:3PR2|rcsb pdb:4HN4|rcsb pdb:4HPJ|rcsb pdb:4HPX|rcsb pdb:4HT3|rcsb pdb:4KKX|rcsb pdb:4WX2|rcsb pdb:4XUG|rcsb pdb:4Y6G|rcsb pdb:4ZQC|rcsb pdb:5BW6|rcsb pdb:1K7E|rcsb pdb:5CGQ|rcsb pdb:6C73|rcsb pdb:6D0V|rcsb pdb:6DUC|rcsb pdb:6DZ4|rcsb pdb:6DZO|rcsb pdb:6O1H|rcsb pdb:6OSO|rcsb pdb:6OUY|rcsb pdb:6VFD|rcsb pdb:6WDU|rcsb pdb:6X0C|rcsb pdb:6XE3|rcsb pdb:6VNT|refseq:WP_000443030.1|dip:DIP-1033N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zPCoRC2efpWAdh4WwPAZkY1lo3M99287 rogid:qsq85k9XUVTr6UgrkQ8m6EvVoIg99287 rigid:I1H03Vfdn0sLqTLijCB5exK7p8s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02701 uniprotkb:P02701 intact:EBI-16064458|ensembl:ENSGALP00000003846|uniprotkb:Q91958|uniprotkb:Q98SH4 intact:EBI-16064458|ensembl:ENSGALP00000003846|uniprotkb:Q91958|uniprotkb:Q98SH4 psi-mi:avid_chick(display_long)|uniprotkb:AVD(gene name)|psi-mi:AVD(display_short) psi-mi:avid_chick(display_long)|uniprotkb:AVD(gene name)|psi-mi:AVD(display_short) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064506|imex:IM-21554-9|dip:DIP-191944E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000025945(gene)|ensembl:ENSGALT00000003855(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009374"(biotin binding)|go:"GO:0019731"(antibacterial humoral response)|interpro:IPR005468(Avidin/streptavidin)|interpro:IPR005469(Avidin)|interpro:IPR017889|interpro:IPR036896|rcsb pdb:1AVD|rcsb pdb:1AVE|rcsb pdb:1IJ8|rcsb pdb:1LDO|rcsb pdb:1LDQ|rcsb pdb:1LEL|rcsb pdb:1NQN|rcsb pdb:1RAV|rcsb pdb:1VYO|rcsb pdb:2A5C|rcsb pdb:2A8G|rcsb pdb:2AVI|rcsb pdb:2C4I|rcsb pdb:2CAM|rcsb pdb:2JGS|rcsb pdb:2MF6|rcsb pdb:3FDC|rcsb pdb:3MM0|rcsb pdb:3VGW|rcsb pdb:3VHH|rcsb pdb:3VHI|rcsb pdb:3VHM|rcsb pdb:4I60|rcsb pdb:4JHQ|rcsb pdb:4U46|rcsb pdb:2A5B|rcsb pdb:5CHK|rcsb pdb:5HLM|rcsb pdb:5IRU|rcsb pdb:5LUR|rcsb pdb:5MYQ|rcsb pdb:6XND|rcsb pdb:5IRW|refseq:NP_990651.1|dip:DIP-60471N ensembl:ENSGALG00000025945(gene)|ensembl:ENSGALT00000003855(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0009374"(biotin binding)|go:"GO:0019731"(antibacterial humoral response)|interpro:IPR005468(Avidin/streptavidin)|interpro:IPR005469(Avidin)|interpro:IPR017889|interpro:IPR036896|rcsb pdb:1AVD|rcsb pdb:1AVE|rcsb pdb:1IJ8|rcsb pdb:1LDO|rcsb pdb:1LDQ|rcsb pdb:1LEL|rcsb pdb:1NQN|rcsb pdb:1RAV|rcsb pdb:1VYO|rcsb pdb:2A5C|rcsb pdb:2A8G|rcsb pdb:2AVI|rcsb pdb:2C4I|rcsb pdb:2CAM|rcsb pdb:2JGS|rcsb pdb:2MF6|rcsb pdb:3FDC|rcsb pdb:3MM0|rcsb pdb:3VGW|rcsb pdb:3VHH|rcsb pdb:3VHI|rcsb pdb:3VHM|rcsb pdb:4I60|rcsb pdb:4JHQ|rcsb pdb:4U46|rcsb pdb:2A5B|rcsb pdb:5CHK|rcsb pdb:5HLM|rcsb pdb:5IRU|rcsb pdb:5LUR|rcsb pdb:5MYQ|rcsb pdb:6XND|rcsb pdb:5IRW|refseq:NP_990651.1|dip:DIP-60471N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2017/08/07 2017/08/10 rogid:CcxAFiN8GIAaitioLT507bfCEB49031 rogid:CcxAFiN8GIAaitioLT507bfCEB49031 rigid:o/TV5318UfqCZ0TL01mtLIsC8uE false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00366 uniprotkb:P00366 intact:EBI-1221442|uniprotkb:Q7YS29|uniprotkb:Q8HZ49|uniprotkb:Q3SYY0 intact:EBI-1221442|uniprotkb:Q7YS29|uniprotkb:Q8HZ49|uniprotkb:Q3SYY0 psi-mi:dhe3_bovin(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:dhe3_bovin(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16064442|imex:IM-21554-8|dip:DIP-191947E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_872593.2|dip:DIP-39002N|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|rcsb pdb:1HWY|rcsb pdb:1NQT|rcsb pdb:1NR7|rcsb pdb:3ETD|rcsb pdb:3ETE|rcsb pdb:3ETG|rcsb pdb:3JCZ|rcsb pdb:3JD0|rcsb pdb:3JD1|rcsb pdb:3JD2|rcsb pdb:3JD3|rcsb pdb:3JD4|rcsb pdb:5K12|rcsb pdb:6DHD|rcsb pdb:6DHK|rcsb pdb:6DHL|rcsb pdb:6DHM|rcsb pdb:6DHN|rcsb pdb:6DHQ|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region) refseq:NP_872593.2|dip:DIP-39002N|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|rcsb pdb:1HWY|rcsb pdb:1NQT|rcsb pdb:1NR7|rcsb pdb:3ETD|rcsb pdb:3ETE|rcsb pdb:3ETG|rcsb pdb:3JCZ|rcsb pdb:3JD0|rcsb pdb:3JD1|rcsb pdb:3JD2|rcsb pdb:3JD3|rcsb pdb:3JD4|rcsb pdb:5K12|rcsb pdb:6DHD|rcsb pdb:6DHK|rcsb pdb:6DHL|rcsb pdb:6DHM|rcsb pdb:6DHN|rcsb pdb:6DHQ|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2017/08/07 2017/08/10 rogid:+3ops5gOvirskO0EY01kOibwcnM9913 rogid:+3ops5gOvirskO0EY01kOibwcnM9913 rigid:n7aU6gGQ7FrR/ck7c7OHizOH7j8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O87798 uniprotkb:O87799 intact:EBI-1038675 intact:EBI-1038659 psi-mi:o87798_psest(display_long)|uniprotkb:touA(gene name)|psi-mi:touA(display_short) psi-mi:o87799_psest(display_long)|uniprotkb:touB(gene name)|psi-mi:touB(display_short) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:316(psest)|taxid:316(Pseudomonas stutzeri) taxid:316(psest)|taxid:316(Pseudomonas stutzeri) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064555|imex:IM-21554-12|dip:DIP-65851E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR003430(Methane/phenol/toluene hydroxylase)|interpro:IPR007029(YHS)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|rcsb pdb:1T0Q|rcsb pdb:1T0R|rcsb pdb:1T0S|rcsb pdb:2INC|rcsb pdb:2IND|rcsb pdb:2RDB|dip:DIP-37865N go:"GO:0004497"(monooxygenase activity)|interpro:IPR009355(Toluene-4-monooxygenase system B)|interpro:IPR036713|rcsb pdb:1T0Q|rcsb pdb:1T0R|rcsb pdb:1T0S|rcsb pdb:2INC|rcsb pdb:2IND|rcsb pdb:2RDB|dip:DIP-37863N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:U7kluHR/ZqWXt9iyhkzhAHr9htE316 rogid:1nV3ra4Q5BRYIMw1UPEtQwJB41k316 rigid:idnfslAGP9rqEdfjpATAe34ZFEM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O87798 uniprotkb:O87802 intact:EBI-1038675 intact:EBI-1038665 psi-mi:o87798_psest(display_long)|uniprotkb:touA(gene name)|psi-mi:touA(display_short) psi-mi:o87802_psest(display_long)|uniprotkb:touE(gene name)|psi-mi:touE(display_short) psi-mi:"MI:1246"(ion mobility mass spectrometry of complexes) Hall et al. (2013) pubmed:23850452|doi:"https://doi.org/10.1016/j.str.2013.06.004"|imex:IM-21554 taxid:316(psest)|taxid:316(Pseudomonas stutzeri) taxid:316(psest)|taxid:316(Pseudomonas stutzeri) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16064555|imex:IM-21554-12|dip:DIP-65851E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004497"(monooxygenase activity)|go:"GO:0006725"(cellular aromatic compound metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR003430(Methane/phenol/toluene hydroxylase)|interpro:IPR007029(YHS)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|rcsb pdb:1T0Q|rcsb pdb:1T0R|rcsb pdb:1T0S|rcsb pdb:2INC|rcsb pdb:2IND|rcsb pdb:2RDB|dip:DIP-37865N go:"GO:0006725"(cellular aromatic compound metabolic process)|interpro:IPR003430(Methane/phenol/toluene hydroxylase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012078(Methane/phenol monooxygenase, hydroxylase component)|interpro:IPR012348(Ribonucleotide reductase-related)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|rcsb pdb:1T0Q|rcsb pdb:1T0R|rcsb pdb:1T0S|rcsb pdb:2INC|rcsb pdb:2IND|rcsb pdb:2RDB|dip:DIP-37864N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:U7kluHR/ZqWXt9iyhkzhAHr9htE316 rogid:G4+8UzUMNcomXJVTlvc0nRnBIuU316 rigid:idnfslAGP9rqEdfjpATAe34ZFEM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)