#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P31224 uniprotkb:P31224 intact:EBI-551006|uniprotkb:Q2MBW5|ensemblbacteria:AAC73564|ensemblbacteria:BAE76241 intact:EBI-551006|uniprotkb:Q2MBW5|ensemblbacteria:AAC73564|ensemblbacteria:BAE76241 psi-mi:acrb_ecoli(display_long)|uniprotkb:acrB(gene name)|psi-mi:acrB(display_short)|uniprotkb:acrE(gene name synonym)|uniprotkb:b0462(locus name)|uniprotkb:JW0451(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrB(gene name synonym)|uniprotkb:Acridine resistance protein B(gene name synonym) psi-mi:acrb_ecoli(display_long)|uniprotkb:acrB(gene name)|psi-mi:acrB(display_short)|uniprotkb:acrE(gene name synonym)|uniprotkb:b0462(locus name)|uniprotkb:JW0451(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrB(gene name synonym)|uniprotkb:Acridine resistance protein B(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Nakashima et al. (2013) pubmed:23812586|doi:10.1038/nature12300|imex:IM-21831 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16063142|imex:IM-21831-1|dip:DIP-56546E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_414995.1|refseq:WP_001132469.1|dip:DIP-9049N|ensemblbacteria:AAC73564(transcript)|ensemblbacteria:b0462(gene)|ensemblbacteria:BAE76241(gene)|ensemblbacteria:BAE76241(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:1990281"(efflux pump complex)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|rcsb pdb:1IWG|rcsb pdb:1OY6|rcsb pdb:1OY8|rcsb pdb:1OY9|rcsb pdb:1OYD|rcsb pdb:1OYE|rcsb pdb:1T9T|rcsb pdb:1T9U|rcsb pdb:1T9V|rcsb pdb:1T9W|rcsb pdb:1T9X|rcsb pdb:1T9Y|rcsb pdb:2DHH|rcsb pdb:2DR6|rcsb pdb:2DRD|rcsb pdb:2GIF|rcsb pdb:2HQC|rcsb pdb:2HQD|rcsb pdb:2HQF|rcsb pdb:2HQG|rcsb pdb:2HRT|rcsb pdb:2I6W|rcsb pdb:2J8S|rcsb pdb:2RDD|rcsb pdb:2W1B|rcsb pdb:3AOA|rcsb pdb:3AOB|rcsb pdb:3AOC|rcsb pdb:3AOD|rcsb pdb:3D9B|rcsb pdb:3NOC|rcsb pdb:3NOG|rcsb pdb:3W9H|rcsb pdb:4C48|rcsb pdb:4CDI|rcsb pdb:4DX5|rcsb pdb:4DX6|rcsb pdb:4DX7|rcsb pdb:4K7Q|rcsb pdb:4U8V|rcsb pdb:4U8Y|rcsb pdb:4U95|rcsb pdb:4U96|rcsb pdb:4ZIT|rcsb pdb:4ZIV|rcsb pdb:4ZIW|rcsb pdb:4ZJL|rcsb pdb:4ZJO|rcsb pdb:4ZJQ|rcsb pdb:4ZLJ|rcsb pdb:4ZLL|rcsb pdb:4ZLN|rcsb pdb:5EN5|rcsb pdb:5ENO|rcsb pdb:5ENP|rcsb pdb:5ENQ|rcsb pdb:5ENR|rcsb pdb:5ENS|rcsb pdb:5ENT|rcsb pdb:5JMN|rcsb pdb:5NC5|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:5YIL|rcsb pdb:6BAJ|rcsb pdb:6CSX|rcsb pdb:6Q4N|rcsb pdb:6Q4O|rcsb pdb:6Q4P|rcsb pdb:6SGR|rcsb pdb:6SGS|rcsb pdb:6SGT|rcsb pdb:6SGU|rcsb pdb:6ZO5|rcsb pdb:6ZO6|rcsb pdb:6ZO7|rcsb pdb:6ZO8|rcsb pdb:6ZO9|rcsb pdb:6ZOA|rcsb pdb:6ZOB|rcsb pdb:6ZOC|rcsb pdb:6ZOD|rcsb pdb:6ZOE|rcsb pdb:6ZOF|rcsb pdb:6ZOG|rcsb pdb:6ZOH refseq:NP_414995.1|refseq:WP_001132469.1|dip:DIP-9049N|ensemblbacteria:AAC73564(transcript)|ensemblbacteria:b0462(gene)|ensemblbacteria:BAE76241(gene)|ensemblbacteria:BAE76241(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:1990281"(efflux pump complex)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|rcsb pdb:1IWG|rcsb pdb:1OY6|rcsb pdb:1OY8|rcsb pdb:1OY9|rcsb pdb:1OYD|rcsb pdb:1OYE|rcsb pdb:1T9T|rcsb pdb:1T9U|rcsb pdb:1T9V|rcsb pdb:1T9W|rcsb pdb:1T9X|rcsb pdb:1T9Y|rcsb pdb:2DHH|rcsb pdb:2DR6|rcsb pdb:2DRD|rcsb pdb:2GIF|rcsb pdb:2HQC|rcsb pdb:2HQD|rcsb pdb:2HQF|rcsb pdb:2HQG|rcsb pdb:2HRT|rcsb pdb:2I6W|rcsb pdb:2J8S|rcsb pdb:2RDD|rcsb pdb:2W1B|rcsb pdb:3AOA|rcsb pdb:3AOB|rcsb pdb:3AOC|rcsb pdb:3AOD|rcsb pdb:3D9B|rcsb pdb:3NOC|rcsb pdb:3NOG|rcsb pdb:3W9H|rcsb pdb:4C48|rcsb pdb:4CDI|rcsb pdb:4DX5|rcsb pdb:4DX6|rcsb pdb:4DX7|rcsb pdb:4K7Q|rcsb pdb:4U8V|rcsb pdb:4U8Y|rcsb pdb:4U95|rcsb pdb:4U96|rcsb pdb:4ZIT|rcsb pdb:4ZIV|rcsb pdb:4ZIW|rcsb pdb:4ZJL|rcsb pdb:4ZJO|rcsb pdb:4ZJQ|rcsb pdb:4ZLJ|rcsb pdb:4ZLL|rcsb pdb:4ZLN|rcsb pdb:5EN5|rcsb pdb:5ENO|rcsb pdb:5ENP|rcsb pdb:5ENQ|rcsb pdb:5ENR|rcsb pdb:5ENS|rcsb pdb:5ENT|rcsb pdb:5JMN|rcsb pdb:5NC5|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:5YIL|rcsb pdb:6BAJ|rcsb pdb:6CSX|rcsb pdb:6Q4N|rcsb pdb:6Q4O|rcsb pdb:6Q4P|rcsb pdb:6SGR|rcsb pdb:6SGS|rcsb pdb:6SGT|rcsb pdb:6SGU|rcsb pdb:6ZO5|rcsb pdb:6ZO6|rcsb pdb:6ZO7|rcsb pdb:6ZO8|rcsb pdb:6ZO9|rcsb pdb:6ZOA|rcsb pdb:6ZOB|rcsb pdb:6ZOC|rcsb pdb:6ZOD|rcsb pdb:6ZOE|rcsb pdb:6ZOF|rcsb pdb:6ZOG|rcsb pdb:6ZOH psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:c4g5xahCoi9NOgjxyZoC8WzQpnc83333 rogid:c4g5xahCoi9NOgjxyZoC8WzQpnc83333 rigid:6xRTgf7/utLyOx56ebRHPAKnN3A false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52002 uniprotkb:P52002 intact:EBI-6400435|ensemblbacteria:AAG03815|uniprotkb:Q9S505 intact:EBI-6400435|ensemblbacteria:AAG03815|uniprotkb:Q9S505 psi-mi:mexb_pseae(display_long)|uniprotkb:Multidrug-efflux transporter MexB(gene name synonym)|uniprotkb:PA0426(locus name)|uniprotkb:mexB(gene name)|psi-mi:mexB(display_short) psi-mi:mexb_pseae(display_long)|uniprotkb:Multidrug-efflux transporter MexB(gene name synonym)|uniprotkb:PA0426(locus name)|uniprotkb:mexB(gene name)|psi-mi:mexB(display_short) psi-mi:"MI:0114"(x-ray crystallography) Nakashima et al. (2013) pubmed:23812586|doi:10.1038/nature12300|imex:IM-21831 taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16063160|imex:IM-21831-2|dip:DIP-192227E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAG03815(transcript)|ensemblbacteria:PA0426(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|rcsb pdb:2V50|rcsb pdb:3W9I|rcsb pdb:3W9J|rcsb pdb:6IIA|rcsb pdb:6IOK|rcsb pdb:6IOL|rcsb pdb:6T7S|rcsb pdb:6TA5|rcsb pdb:6TA6|refseq:NP_249117.1|refseq:WP_003107312.1|dip:DIP-60510N ensemblbacteria:AAG03815(transcript)|ensemblbacteria:PA0426(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|interpro:IPR001036(Acriflavin resistance protein)|interpro:IPR004764(Hydrophobe/amphiphile efflux-1 HAE1)|interpro:IPR027463|rcsb pdb:2V50|rcsb pdb:3W9I|rcsb pdb:3W9J|rcsb pdb:6IIA|rcsb pdb:6IOK|rcsb pdb:6IOL|rcsb pdb:6T7S|rcsb pdb:6TA5|rcsb pdb:6TA6|refseq:NP_249117.1|refseq:WP_003107312.1|dip:DIP-60510N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uRtmabVKHE9WHJKQxQmpG6LiQkg208964 rogid:uRtmabVKHE9WHJKQxQmpG6LiQkg208964 rigid:8ZaDMj93ShLaPodvFSvM3U+cKhg false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)