#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50503 uniprotkb:P50503 intact:EBI-917694|ensembl:ENSRNOP00000025925 intact:EBI-917694|ensembl:ENSRNOP00000025925 psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Li et al. (2013) doi:10.1038/nsmb.2608|imex:IM-21587|pubmed:23812373 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16247461|imex:IM-21587-1|dip:DIP-191995E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/10 2017/08/10 rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 rigid:CcqZmmlk12/SYtLDwYMXQok47X8 false sufficient binding region:1-44 sufficient binding region:1-44 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50503 uniprotkb:P50503 intact:EBI-917694|ensembl:ENSRNOP00000025925 intact:EBI-917694|ensembl:ENSRNOP00000025925 psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Li et al. (2013) doi:10.1038/nsmb.2608|imex:IM-21587|pubmed:23812373 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16247507|imex:IM-21587-3|dip:DIP-191995E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/10 2017/08/10 rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 rigid:CcqZmmlk12/SYtLDwYMXQok47X8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-11820565 uniprotkb:P50503 - intact:EBI-917694|ensembl:ENSRNOP00000025925 psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long) psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Li et al. (2013) doi:10.1038/nsmb.2608|imex:IM-21587|pubmed:23812373 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16247523|imex:IM-21587-4|dip:DIP-191996E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:1304"(molecule set) psi-mi:"MI:0326"(protein) - rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N psi-mi:"MI:0465"(dip) comment:P0DMV8,P0DMV9 - comment:Deletion of region 235-247 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2020/10/15 - rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 - false sufficient binding region:1-382 sufficient binding region:78-247|mutation disrupting interaction strength:177-177|mutation disrupting interaction strength:179-179,177-177|mutation disrupting interaction strength:210-210|mutation disrupting interaction strength:212-212,211-211|mutation decreasing interaction strength:117-117|mutation decreasing interaction strength:236-236,235-235|mutation disrupting interaction strength:180-180|mutation increasing interaction strength:148-148 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-11820565 uniprotkb:P50503 - intact:EBI-917694|ensembl:ENSRNOP00000025925 psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long) psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Li et al. (2013) doi:10.1038/nsmb.2608|imex:IM-21587|pubmed:23812373 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16247479|imex:IM-21587-2|dip:DIP-191996E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:1304"(molecule set) psi-mi:"MI:0326"(protein) - rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N psi-mi:"MI:0465"(dip) comment:P0DMV8,P0DMV9 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2020/10/15 - rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 - false sufficient binding region:1-382 sufficient binding region:78-247|mutation decreasing interaction strength:177-177|mutation disrupting interaction strength:212-212,211-211 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-11820565 uniprotkb:P50503 - intact:EBI-917694|ensembl:ENSRNOP00000025925 psi-mi:hspa1a_hspa1b_human-1(display_short)|psi-mi:EBI-11820565(display_long) psi-mi:f10a1_rat(display_long)|uniprotkb:Protein ST13 homolog(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:St13(gene name)|psi-mi:St13(display_short)|uniprotkb:Fam10a1(gene name synonym)|uniprotkb:Hip(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Li et al. (2013) doi:10.1038/nsmb.2608|imex:IM-21587|pubmed:23812373 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16247572|imex:IM-21587-5|dip:DIP-191996E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:1304"(molecule set) psi-mi:"MI:0326"(protein) - rgd:621312|refseq:NP_112384.1|ensembl:ENSRNOG00000019070(gene)|ensembl:ENSRNOT00000025925(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|rcsb pdb:4J8C|rcsb pdb:4J8D|rcsb pdb:4J8E|rcsb pdb:4J8F|reactome:R-RNO-3371453|dip:DIP-37019N psi-mi:"MI:0465"(dip) comment:P0DMV8,P0DMV9 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/10 2020/10/15 - rogid:WSD2xNhhB9fSCire077pTXeV/gk10116 - false sufficient binding region:1-382|mutation disrupting interaction strength:204-204 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)