#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35303 uniprotkb:P53563-1 intact:EBI-1767447|uniprotkb:O35318|uniprotkb:O35319|uniprotkb:O35320|uniprotkb:O35321|uniprotkb:O35322|uniprotkb:O35323|uniprotkb:Q5U2W1|uniprotkb:Q792T7|uniprotkb:Q9R234|uniprotkb:Q9R277|ensembl:ENSRNOP00000002478 intact:EBI-287204|ensembl:ENSRNOP00000010762 psi-mi:dnm1l_rat(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Dlp1(gene name synonym)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym) psi-mi:p53563-1(display_long)|uniprotkb:Bcl-xL(isoform synonym)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Blc2l(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16062655|imex:IM-22376-1|dip:DIP-195944E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620416|refseq:NP_446107.2|refseq:XP_008767063.1|refseq:XP_008767064.1|refseq:XP_008767065.1|refseq:XP_006248785.1|dip:DIP-29699N|ensembl:ENSRNOG00000001813(gene)|ensembl:ENSRNOT00000002478(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O35303|reactome:R-RNO-75153|interpro:IPR001401(Dynamin, GTPase region) intact:EBI-79042(bclx_rat)|ensembl:ENSRNOG00000007946(gene)|ensembl:ENSRNOT00000010762(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:HkPGbvyZ4Tb3hJw1EqAya+FIcWg10116 rogid:m7nX0kI88bULKwTHnxoTthhv8ZY10116 rigid:Jw1kCMdYh3248IuHOidvBb1StvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O35303 uniprotkb:P08081 intact:EBI-1767447|uniprotkb:O35318|uniprotkb:O35319|uniprotkb:O35320|uniprotkb:O35321|uniprotkb:O35322|uniprotkb:O35323|uniprotkb:Q5U2W1|uniprotkb:Q792T7|uniprotkb:Q9R234|uniprotkb:Q9R277|ensembl:ENSRNOP00000002478 intact:EBI-916140|ensembl:ENSRNOP00000019737 psi-mi:dnm1l_rat(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Dlp1(gene name synonym)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym) psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16062655|imex:IM-22376-1|dip:DIP-195944E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620416|refseq:NP_446107.2|refseq:XP_008767063.1|refseq:XP_008767064.1|refseq:XP_008767065.1|refseq:XP_006248785.1|dip:DIP-29699N|ensembl:ENSRNOG00000001813(gene)|ensembl:ENSRNOT00000002478(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O35303|reactome:R-RNO-75153|interpro:IPR001401(Dynamin, GTPase region) ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:HkPGbvyZ4Tb3hJw1EqAya+FIcWg10116 rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116 rigid:Jw1kCMdYh3248IuHOidvBb1StvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O35303 uniprotkb:Q4KM98 intact:EBI-1767447|uniprotkb:O35318|uniprotkb:O35319|uniprotkb:O35320|uniprotkb:O35321|uniprotkb:O35322|uniprotkb:O35323|uniprotkb:Q5U2W1|uniprotkb:Q792T7|uniprotkb:Q9R234|uniprotkb:Q9R277|ensembl:ENSRNOP00000002478 intact:EBI-16062628 psi-mi:dnm1l_rat(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Dlp1(gene name synonym)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym) psi-mi:mff_rat(display_long)|uniprotkb:Mff(gene name)|psi-mi:Mff(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16062655|imex:IM-22376-1|dip:DIP-195944E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620416|refseq:NP_446107.2|refseq:XP_008767063.1|refseq:XP_008767064.1|refseq:XP_008767065.1|refseq:XP_006248785.1|dip:DIP-29699N|ensembl:ENSRNOG00000001813(gene)|ensembl:ENSRNOT00000002478(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O35303|reactome:R-RNO-75153|interpro:IPR001401(Dynamin, GTPase region) go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR008518(Protein of unknown function DUF800)|interpro:IPR039433|refseq:NP_001034104.1|refseq:NP_001258213.1|refseq:NP_001263330.1|refseq:XP_006245273.2|refseq:XP_008765547.1|refseq:XP_017459407.1|rgd:1310230|dip:DIP-60704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:HkPGbvyZ4Tb3hJw1EqAya+FIcWg10116 rogid:VKQNAgtlDk3i8Ck5z7M1QVv/R7w10116 rigid:Jw1kCMdYh3248IuHOidvBb1StvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P21707 uniprotkb:Q4KM98 intact:EBI-458098|uniprotkb:Q3S2E6|uniprotkb:Q707P5|ensembl:ENSRNOP00000049624|ensembl:ENSRNOP00000069194 intact:EBI-16062628 psi-mi:syt1_rat(display_long)|uniprotkb:Syt1(gene name)|psi-mi:Syt1(display_short)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym) psi-mi:mff_rat(display_long)|uniprotkb:Mff(gene name)|psi-mi:Mff(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16062698|imex:IM-22376-3|dip:DIP-195945E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3803|refseq:NP_001028852.2|ensembl:ENSRNOG00000006426(gene)|ensembl:ENSRNOT00000048880(transcript)|ensembl:ENSRNOT00000088950(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P21707|rcsb pdb:1BYN|rcsb pdb:1K5W|rcsb pdb:1RSY|rcsb pdb:1TJM|rcsb pdb:1TJX|rcsb pdb:1UOV|rcsb pdb:1UOW|rcsb pdb:2YOA|rcsb pdb:4WEE|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5CCJ|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6CXW|rcsb pdb:6MTI|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-888590|refseq:XP_017450168.1|dip:DIP-29064N go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR008518(Protein of unknown function DUF800)|interpro:IPR039433|refseq:NP_001034104.1|refseq:NP_001258213.1|refseq:NP_001263330.1|refseq:XP_006245273.2|refseq:XP_008765547.1|refseq:XP_017459407.1|rgd:1310230|dip:DIP-60704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:fr7zfj22zAOY/bJ7psjrgnsb0g810116 rogid:VKQNAgtlDk3i8Ck5z7M1QVv/R7w10116 rigid:KZ9PiCUvgVXIeQSEbb1c2uNaLgw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53563-1 uniprotkb:P08081 intact:EBI-287204|ensembl:ENSRNOP00000010762 intact:EBI-916140|ensembl:ENSRNOP00000019737 psi-mi:p53563-1(display_long)|uniprotkb:Bcl-xL(isoform synonym)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Blc2l(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16062715|imex:IM-22376-4|dip:DIP-195946E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-79042(bclx_rat)|ensembl:ENSRNOG00000007946(gene)|ensembl:ENSRNOT00000010762(transcript) ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:m7nX0kI88bULKwTHnxoTthhv8ZY10116 rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116 rigid:lbpFOyjGnhAde0BBnH8SakA2x4k false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00429-1 uniprotkb:Q07817-1 intact:EBI-15690834|ensembl:ENSP00000450399 intact:EBI-287195|ensembl:ENSP00000302564|ensembl:ENSP00000365230|ensembl:ENSP00000389688|ensembl:ENSP00000390760|ensembl:ENSP00000395545|ensembl:ENSP00000401173|ensembl:ENSP00000503725|ensembl:ENSP00000504237|ensembl:ENSP00000504387|ensembl:ENSP00000504536|intact:EBI-8058735|intact:MINT-89566|intact:EBI-8058554|intact:EBI-8058512|intact:EBI-8058443 psi-mi:o00429-1(display_long)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:DLP1F(isoform synonym)|uniprotkb:HdynIV-WT(isoform synonym) psi-mi:q07817-1(display_long)|uniprotkb:BCLX(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym)|uniprotkb:BCL2L1(gene name)|psi-mi:BCL2L1(display_short)|uniprotkb:BCL2L(gene name synonym)|uniprotkb:Bcl-xL(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16062674|imex:IM-22376-2|dip:DIP-195947E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|intact:EBI-724571(isoform-parent) intact:EBI-78035(bclx_human)|ensembl:ENSG00000171552(gene)|ensembl:ENST00000678563(transcript)|ensembl:ENST00000307677(transcript)|ensembl:ENST00000376062(transcript)|ensembl:ENST00000420488(transcript)|ensembl:ENST00000434194(transcript)|ensembl:ENST00000439267(transcript)|ensembl:ENST00000456404(transcript)|ensembl:ENST00000676582(transcript)|ensembl:ENST00000676942(transcript)|ensembl:ENST00000677194(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rogid:lDDsMUf2W6uLKpfM3h4N364tpWg9606 rigid:+53IEqKnHu4/6PfyuiCNRiWvgsA false - mutation disrupting interaction strength:191-191,189-189,188-188|flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53563-1 uniprotkb:P08081 intact:EBI-287204|ensembl:ENSRNOP00000010762 intact:EBI-916140|ensembl:ENSRNOP00000019737 psi-mi:p53563-1(display_long)|uniprotkb:Bcl-xL(isoform synonym)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Blc2l(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16062732|imex:IM-22376-5|dip:DIP-195944E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-79042(bclx_rat)|ensembl:ENSRNOG00000007946(gene)|ensembl:ENSRNOT00000010762(transcript) ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:m7nX0kI88bULKwTHnxoTthhv8ZY10116 rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116 rigid:Jw1kCMdYh3248IuHOidvBb1StvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53563-1 uniprotkb:Q4KM98 intact:EBI-287204|ensembl:ENSRNOP00000010762 intact:EBI-16062628 psi-mi:p53563-1(display_long)|uniprotkb:Bcl-xL(isoform synonym)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Blc2l(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:mff_rat(display_long)|uniprotkb:Mff(gene name)|psi-mi:Mff(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16062732|imex:IM-22376-5|dip:DIP-195944E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-79042(bclx_rat)|ensembl:ENSRNOG00000007946(gene)|ensembl:ENSRNOT00000010762(transcript) go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR008518(Protein of unknown function DUF800)|interpro:IPR039433|refseq:NP_001034104.1|refseq:NP_001258213.1|refseq:NP_001263330.1|refseq:XP_006245273.2|refseq:XP_008765547.1|refseq:XP_017459407.1|rgd:1310230|dip:DIP-60704N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:m7nX0kI88bULKwTHnxoTthhv8ZY10116 rogid:VKQNAgtlDk3i8Ck5z7M1QVv/R7w10116 rigid:Jw1kCMdYh3248IuHOidvBb1StvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53563-1 uniprotkb:O35303 intact:EBI-287204|ensembl:ENSRNOP00000010762 intact:EBI-1767447|uniprotkb:O35318|uniprotkb:O35319|uniprotkb:O35320|uniprotkb:O35321|uniprotkb:O35322|uniprotkb:O35323|uniprotkb:Q5U2W1|uniprotkb:Q792T7|uniprotkb:Q9R234|uniprotkb:Q9R277|ensembl:ENSRNOP00000002478 psi-mi:p53563-1(display_long)|uniprotkb:Bcl-xL(isoform synonym)|uniprotkb:Bcl2l1(gene name)|psi-mi:Bcl2l1(display_short)|uniprotkb:Bclx(gene name synonym)|uniprotkb:Blc2l(gene name synonym)|uniprotkb:Apoptosis regulator Bcl-X(gene name synonym) psi-mi:dnm1l_rat(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Dlp1(gene name synonym)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2013) pubmed:23792689|doi:10.1038/ncb2791|imex:IM-22376 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16062732|imex:IM-22376-5|dip:DIP-195944E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-79042(bclx_rat)|ensembl:ENSRNOG00000007946(gene)|ensembl:ENSRNOT00000010762(transcript) rgd:620416|refseq:NP_446107.2|refseq:XP_008767063.1|refseq:XP_008767064.1|refseq:XP_008767065.1|refseq:XP_006248785.1|dip:DIP-29699N|ensembl:ENSRNOG00000001813(gene)|ensembl:ENSRNOT00000002478(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O35303|reactome:R-RNO-75153|interpro:IPR001401(Dynamin, GTPase region) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:m7nX0kI88bULKwTHnxoTthhv8ZY10116 rogid:HkPGbvyZ4Tb3hJw1EqAya+FIcWg10116 rigid:Jw1kCMdYh3248IuHOidvBb1StvA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)