#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9DC51	uniprotkb:Q8VDU0	intact:EBI-641852|uniprotkb:Q3TGV1|uniprotkb:Q61019|uniprotkb:A2AE36|ensembl:ENSMUSP00000000001	intact:EBI-7575403|uniprotkb:Q8BLX3|intact:MINT-4096561|ensembl:ENSMUSP00000029482	psi-mi:gnai3_mouse(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short)	psi-mi:gpsm2_mouse(display_long)|uniprotkb:Gpsm2(gene name)|psi-mi:Gpsm2(display_short)|uniprotkb:Lgn(gene name synonym)|uniprotkb:Pins(gene name synonym)|uniprotkb:Pins homolog(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Pan et al. (2013)	pubmed:23665171|doi:10.1016/j.str.2013.04.005|imex:IM-21033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16057824|imex:IM-21033-1|dip:DIP-190650E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034436.1|dip:DIP-49479N|ensembl:ENSMUSG00000000001(gene)|ensembl:ENSMUST00000000001(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q9DC51|rcsb pdb:3AB3|reactome:R-MMU-170670|reactome:R-MMU-392170|reactome:R-MMU-418594|reactome:R-MMU-9009391	refseq:NP_083798.2|ensembl:ENSMUSG00000027883(gene)|ensembl:ENSMUST00000029482(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q8VDU0|rcsb pdb:3RO2|rcsb pdb:3RO3|rcsb pdb:4G2V|rcsb pdb:4G5O|rcsb pdb:4G5Q|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:4JHR|reactome:R-MMU-418594|dip:DIP-60164N	psi-mi:"MI:0465"(dip)	-	comment:mint|comment:homomint|function:"Plays an important role in spindle pole orientation (By similarity). Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions"	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:YJ4mEQU/4IYIxCCj7qgeNh92TNc10090	rogid:7VdCk+rhJu/c4S+qR6g1X2lazuk10090	rigid:apqM0+euPBW3mUlSPFmnT59d0jY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9DC51	uniprotkb:Q14980-2	intact:EBI-641852|uniprotkb:Q3TGV1|uniprotkb:Q61019|uniprotkb:A2AE36|ensembl:ENSMUSP00000000001	intact:EBI-10981450|ensembl:ENSP00000351851|ensembl:ENSP00000478624	psi-mi:gnai3_mouse(display_long)|uniprotkb:"G(i) alpha-3"(gene name synonym)|uniprotkb:Gnai3(gene name)|psi-mi:Gnai3(display_short)	psi-mi:q14980-2(display_long)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NMP22(gene name synonym)|uniprotkb:NUMA(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:SP-H antigen(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Pan et al. (2013)	pubmed:23665171|doi:10.1016/j.str.2013.04.005|imex:IM-21033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16057824|imex:IM-21033-1|dip:DIP-190650E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034436.1|dip:DIP-49479N|ensembl:ENSMUSG00000000001(gene)|ensembl:ENSMUST00000000001(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:Q9DC51|rcsb pdb:3AB3|reactome:R-MMU-170670|reactome:R-MMU-392170|reactome:R-MMU-418594|reactome:R-MMU-9009391	intact:EBI-521611(isoform-parent)|uniprotkb:Q14980-2(isoform-parent)|ensembl:ENSG00000137497(gene)|ensembl:ENST00000358965(transcript)|ensembl:ENST00000620566(transcript)	psi-mi:"MI:0465"(dip)	-	isoform-comment:No experimental confirmation available.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:YJ4mEQU/4IYIxCCj7qgeNh92TNc10090	rogid:k+pBQcdLaMXB7W5PGtmeCUtJOqY9606	rigid:apqM0+euPBW3mUlSPFmnT59d0jY	false	-	sufficient binding region:1886-1958	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8VDU0	uniprotkb:Q14980-2	intact:EBI-7575403|uniprotkb:Q8BLX3|intact:MINT-4096561|ensembl:ENSMUSP00000029482	intact:EBI-10981450|ensembl:ENSP00000351851|ensembl:ENSP00000478624	psi-mi:gpsm2_mouse(display_long)|uniprotkb:Gpsm2(gene name)|psi-mi:Gpsm2(display_short)|uniprotkb:Lgn(gene name synonym)|uniprotkb:Pins(gene name synonym)|uniprotkb:Pins homolog(gene name synonym)	psi-mi:q14980-2(display_long)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NMP22(gene name synonym)|uniprotkb:NUMA(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:SP-H antigen(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Pan et al. (2013)	pubmed:23665171|doi:10.1016/j.str.2013.04.005|imex:IM-21033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16057844|imex:IM-21033-2|dip:DIP-190651E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083798.2|ensembl:ENSMUSG00000027883(gene)|ensembl:ENSMUST00000029482(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q8VDU0|rcsb pdb:3RO2|rcsb pdb:3RO3|rcsb pdb:4G2V|rcsb pdb:4G5O|rcsb pdb:4G5Q|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:4JHR|reactome:R-MMU-418594|dip:DIP-60164N	intact:EBI-521611(isoform-parent)|uniprotkb:Q14980-2(isoform-parent)|ensembl:ENSG00000137497(gene)|ensembl:ENST00000358965(transcript)|ensembl:ENST00000620566(transcript)	psi-mi:"MI:0465"(dip)	comment:mint|comment:homomint|function:"Plays an important role in spindle pole orientation (By similarity). Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions"	isoform-comment:No experimental confirmation available.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:7VdCk+rhJu/c4S+qR6g1X2lazuk10090	rogid:k+pBQcdLaMXB7W5PGtmeCUtJOqY9606	rigid:dQwC7K9KN/K4C/KDHOkPLEKLqHY	false	sufficient binding region:15-350	sufficient binding region:1896-1912|fluorescein isothiocyanate label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8VDU0	uniprotkb:Q14980-2	intact:EBI-7575403|uniprotkb:Q8BLX3|intact:MINT-4096561|ensembl:ENSMUSP00000029482	intact:EBI-10981450|ensembl:ENSP00000351851|ensembl:ENSP00000478624	psi-mi:gpsm2_mouse(display_long)|uniprotkb:Gpsm2(gene name)|psi-mi:Gpsm2(display_short)|uniprotkb:Lgn(gene name synonym)|uniprotkb:Pins(gene name synonym)|uniprotkb:Pins homolog(gene name synonym)	psi-mi:q14980-2(display_long)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NMP22(gene name synonym)|uniprotkb:NUMA(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:SP-H antigen(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Pan et al. (2013)	pubmed:23665171|doi:10.1016/j.str.2013.04.005|imex:IM-21033	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16057869|imex:IM-21033-3|dip:DIP-190651E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083798.2|ensembl:ENSMUSG00000027883(gene)|ensembl:ENSMUST00000029482(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003109(GoLoco)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q8VDU0|rcsb pdb:3RO2|rcsb pdb:3RO3|rcsb pdb:4G2V|rcsb pdb:4G5O|rcsb pdb:4G5Q|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:4JHR|reactome:R-MMU-418594|dip:DIP-60164N	intact:EBI-521611(isoform-parent)|uniprotkb:Q14980-2(isoform-parent)|ensembl:ENSG00000137497(gene)|ensembl:ENST00000358965(transcript)|ensembl:ENST00000620566(transcript)	psi-mi:"MI:0465"(dip)	comment:mint|comment:homomint|function:"Plays an important role in spindle pole orientation (By similarity). Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions"	isoform-comment:No experimental confirmation available.	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:7VdCk+rhJu/c4S+qR6g1X2lazuk10090	rogid:k+pBQcdLaMXB7W5PGtmeCUtJOqY9606	rigid:dQwC7K9KN/K4C/KDHOkPLEKLqHY	false	sufficient binding region:15-350	sufficient binding region:1886-1958	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)