#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9HXM5	uniprotkb:Q9HXM5	intact:EBI-16056797|ensemblbacteria:AAG07157	intact:EBI-16056797|ensemblbacteria:AAG07157	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Labesse et al. (2013)	pubmed:23643948|doi:10.1016/j.str.2013.03.011|imex:IM-21029	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16056823|imex:IM-21029-1|dip:DIP-190644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rigid:CEbxFJNC2R8ZBFF9eQYFtgscE8I	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20839-1	uniprotkb:P20839-1	intact:EBI-16056855	intact:EBI-16056855	psi-mi:p20839-1(display_long)|uniprotkb:IMPDH1(gene name)|psi-mi:IMPDH1(display_short)|uniprotkb:IMPD1(gene name synonym)|uniprotkb:IMPDH-I(gene name synonym)	psi-mi:p20839-1(display_long)|uniprotkb:IMPDH1(gene name)|psi-mi:IMPDH1(display_short)|uniprotkb:IMPD1(gene name synonym)|uniprotkb:IMPDH-I(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Labesse et al. (2013)	pubmed:23643948|doi:10.1016/j.str.2013.03.011|imex:IM-21029	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16056862|imex:IM-21029-3|dip:DIP-190645E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2866691(isoform-parent)	intact:EBI-2866691(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:avFKvRBQHBqoWUp4+Zos6OsLqfA9606	rogid:avFKvRBQHBqoWUp4+Zos6OsLqfA9606	rigid:Wjq+08FAnyAHUV99C6WSp8XgvhU	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HXM5	uniprotkb:Q9HXM5	intact:EBI-16056797|ensemblbacteria:AAG07157	intact:EBI-16056797|ensemblbacteria:AAG07157	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:"MI:0028"(cosedimentation in solution)	Labesse et al. (2013)	pubmed:23643948|doi:10.1016/j.str.2013.03.011|imex:IM-21029	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16056878|imex:IM-21029-4|dip:DIP-190644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rigid:CEbxFJNC2R8ZBFF9eQYFtgscE8I	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HXM5	uniprotkb:Q9HXM5	intact:EBI-16056797|ensemblbacteria:AAG07157	intact:EBI-16056797|ensemblbacteria:AAG07157	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:"MI:0826"(x ray scattering)	Labesse et al. (2013)	pubmed:23643948|doi:10.1016/j.str.2013.03.011|imex:IM-21029	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16056894|imex:IM-21029-5|dip:DIP-190644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rigid:CEbxFJNC2R8ZBFF9eQYFtgscE8I	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HXM5	uniprotkb:Q9HXM5	intact:EBI-16056797|ensemblbacteria:AAG07157	intact:EBI-16056797|ensemblbacteria:AAG07157	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:"MI:0071"(molecular sieving)	Labesse et al. (2013)	pubmed:23643948|doi:10.1016/j.str.2013.03.011|imex:IM-21029	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16056839|imex:IM-21029-2|dip:DIP-190644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rigid:CEbxFJNC2R8ZBFF9eQYFtgscE8I	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HXM5	uniprotkb:Q9HXM5	intact:EBI-16056797|ensemblbacteria:AAG07157	intact:EBI-16056797|ensemblbacteria:AAG07157	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:q9hxm5_pseae(display_long)|uniprotkb:guaB(gene name)|psi-mi:guaB(display_short)|uniprotkb:PA3770(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Labesse et al. (2013)	pubmed:23643948|doi:10.1016/j.str.2013.03.011|imex:IM-21029	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16056911|imex:IM-21029-6|dip:DIP-190644E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	ensemblbacteria:AAG07157(transcript)|ensemblbacteria:PA3770(gene)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|rcsb pdb:3ZFH|rcsb pdb:4AVF|rcsb pdb:4DQW|rcsb pdb:5AHL|rcsb pdb:5AHM|rcsb pdb:5AHN|rcsb pdb:6GJV|rcsb pdb:6GK9|refseq:NP_252459.1|refseq:WP_003092702.1|dip:DIP-60162N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rogid:PWNI3DqeGqCcFGt1xJF37Tzchn4208964	rigid:CEbxFJNC2R8ZBFF9eQYFtgscE8I	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)