#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q63054 uniprotkb:Q9EP80 intact:EBI-16056269|uniprotkb:Q6P3W0 intact:EBI-77728|uniprotkb:Q546X4|uniprotkb:Q925D1 psi-mi:ica69_rat(display_long)|uniprotkb:Ica1(gene name)|psi-mi:Ica1(display_short)|uniprotkb:69 kDa islet cell autoantigen(gene name synonym)|uniprotkb:Islet cell autoantigen p69(gene name synonym) psi-mi:pick1_rat(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Holst et al. (2012) pubmed:23630454|doi:10.1371/journal.pbio.1001542|imex:IM-21052 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16056296|imex:IM-21052-1|dip:DIP-190679E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051049"(regulation of transport)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR006723(Islet cell autoantigen ICA69 homologue)|interpro:IPR010504(Arfaptin-like)|interpro:IPR024114|interpro:IPR027267|interpro:IPR030796|rgd:621465|dip:DIP-60171N rgd:69437|refseq:NP_445912.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0015872"(dopamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|rcsb pdb:2LUI|rcsb pdb:2PKU|rcsb pdb:3HPK|rcsb pdb:3HPM|reactome:R-RNO-416993|mint:Q9EP80|dip:DIP-30941N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") - 2017/08/07 2017/08/10 rogid:DhvjscANmpNn9V4GU+pN9DwYtu410116 rogid:py6ehB6OMAq34c71Oad5GTeNfHg10116 rigid:vZB8QAj9e0WCH1CQmpKNFkVgFlY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8SY07 uniprotkb:Q9VP78 intact:EBI-173458|uniprotkb:Q9VK66|ensemblmetazoa:FBpp0079976 intact:EBI-154376|ensemblmetazoa:FBpp0077950|ensemblmetazoa:FBpp0293952 psi-mi:q8sy07_drome(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:Dmel\CG6167(gene name synonym)|uniprotkb:dPICK1(gene name synonym)|uniprotkb:CG6167(orf name)|uniprotkb:Dmel_CG6167(orf name)|uniprotkb:Protein interacting with C kinase 1(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym) psi-mi:q9vp78_drome(display_long)|uniprotkb:ICA69(gene name)|psi-mi:ICA69(display_short)|uniprotkb:Dm ric-19(gene name synonym)|uniprotkb:Dmel\CG10566(gene name synonym)|uniprotkb:ICA-69(gene name synonym)|uniprotkb:dCG10566-PA(gene name synonym)|uniprotkb:Dmel_CG10566(orf name)|uniprotkb:CG10566(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Holst et al. (2012) pubmed:23630454|doi:10.1371/journal.pbio.1001542|imex:IM-21052 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16056313|imex:IM-21052-2|dip:DIP-190680E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_609582.3|flybase:FBgn0032447|ensemblmetazoa:FBgn0032447(gene)|ensemblmetazoa:FBtr0080395(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016301"(kinase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0071329"(cellular response to sucrose stimulus)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|go:"GO:0048471"(perinuclear region of cytoplasm) refseq:NP_001246855.1|refseq:NP_649283.1|flybase:FBgn0037050|ensemblmetazoa:FBgn0037050(gene)|ensemblmetazoa:FBtr0078292(transcript)|ensemblmetazoa:FBtr0305500(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051049"(regulation of transport)|go:"GO:0097688"(glutamate receptor clustering)|go:"GO:0097753"(membrane bending)|go:"GO:0098975"(postsynapse of neuromuscular junction)|go:"GO:0099173"(postsynapse organization)|interpro:IPR010504(Arfaptin-like)|interpro:IPR024114|interpro:IPR027267|dip:DIP-60172N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:5HpIawvoaC28nHZN3bhCUpwYeok7227 rogid:0SQ4lg7+6BsIkDOxP9xfHoBVixA7227 rigid:NHNZsuEoibXRBN7Z1FN+UOi4ze4 false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)