#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97411 uniprotkb:Q62083 intact:EBI-16056188|ensembl:ENSMUSP00000040062|ensembl:ENSMUSP00000111182|uniprotkb:E9QLS3|uniprotkb:P97362|uniprotkb:P97954|uniprotkb:Q99M40|uniprotkb:Q9R2C4 intact:EBI-77550|uniprotkb:E9PY04 psi-mi:ica69_mouse(display_long)|uniprotkb:Ica1(gene name)|psi-mi:Ica1(display_short)|uniprotkb:Icap69(gene name synonym)|uniprotkb:69 kDa islet cell autoantigen(gene name synonym)|uniprotkb:Islet cell autoantigen p69(gene name synonym) psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cao et al. (2012) pubmed:23630453|doi:10.1371/journal.pbio.1001541|imex:IM-21051 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16056227|imex:IM-21051-1|dip:DIP-190678E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000062995(gene)|ensembl:ENSMUST00000038403(transcript)|ensembl:ENSMUST00000115520(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051049"(regulation of transport)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR006723(Islet cell autoantigen ICA69 homologue)|interpro:IPR010504(Arfaptin-like)|interpro:IPR024114|interpro:IPR027267|interpro:IPR030796|refseq:NP_001239195.1|refseq:NP_034622.3|refseq:XP_006505056.1|refseq:XP_006505057.1|refseq:XP_006505058.1|dip:DIP-60170N go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:q05BrdYrIby02HSNviESgYS1NLc10090 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 rigid:LVkv7WFjF/ERYtoW8/rgGwZWH7c false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P97411 uniprotkb:Q62083 intact:EBI-16056188|ensembl:ENSMUSP00000040062|ensembl:ENSMUSP00000111182|uniprotkb:E9QLS3|uniprotkb:P97362|uniprotkb:P97954|uniprotkb:Q99M40|uniprotkb:Q9R2C4 intact:EBI-77550|uniprotkb:E9PY04 psi-mi:ica69_mouse(display_long)|uniprotkb:Ica1(gene name)|psi-mi:Ica1(display_short)|uniprotkb:Icap69(gene name synonym)|uniprotkb:69 kDa islet cell autoantigen(gene name synonym)|uniprotkb:Islet cell autoantigen p69(gene name synonym) psi-mi:pick1_mouse(display_long)|uniprotkb:Pick1(gene name)|psi-mi:Pick1(display_short)|uniprotkb:Prkcabp(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cao et al. (2012) pubmed:23630453|doi:10.1371/journal.pbio.1001541|imex:IM-21051 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16056244|imex:IM-21051-2|dip:DIP-190678E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000062995(gene)|ensembl:ENSMUST00000038403(transcript)|ensembl:ENSMUST00000115520(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051049"(regulation of transport)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR006723(Islet cell autoantigen ICA69 homologue)|interpro:IPR010504(Arfaptin-like)|interpro:IPR024114|interpro:IPR027267|interpro:IPR030796|refseq:NP_001239195.1|refseq:NP_034622.3|refseq:XP_006505056.1|refseq:XP_006505057.1|refseq:XP_006505058.1|dip:DIP-60170N go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030425"(dendrite)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|dip:DIP-283N|reactome:R-MMU-416993 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:q05BrdYrIby02HSNviESgYS1NLc10090 rogid:veKbDBj2tGZ1NAtPY6jLz0uNk0010090 rigid:LVkv7WFjF/ERYtoW8/rgGwZWH7c false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)