#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8VE98	uniprotkb:Q8VE98	intact:EBI-16044767|ensembl:ENSMUSP00000042681|ensembl:ENSMUSP00000129418	intact:EBI-16044767|ensembl:ENSMUSP00000042681|ensembl:ENSMUSP00000129418	psi-mi:cd276_mouse(display_long)|uniprotkb:Cd276(gene name)|psi-mi:Cd276(display_short)|uniprotkb:B7h3(gene name synonym)|uniprotkb:B7 homolog 3(gene name synonym)|uniprotkb:Costimulatory molecule(gene name synonym)	psi-mi:cd276_mouse(display_long)|uniprotkb:Cd276(gene name)|psi-mi:Cd276(display_short)|uniprotkb:B7h3(gene name synonym)|uniprotkb:B7 homolog 3(gene name synonym)|uniprotkb:Costimulatory molecule(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Vigdorovich et al. (2013)	pubmed:23583036|doi:10.1016/j.str.2013.03.003|imex:IM-21025	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16044803|imex:IM-21025-1|dip:DIP-190628E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000035914(gene)|ensembl:ENSMUST00000039788(transcript)|ensembl:ENSMUST00000165365(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4I0K|refseq:NP_598744.1|dip:DIP-60156N	ensembl:ENSMUSG00000035914(gene)|ensembl:ENSMUST00000039788(transcript)|ensembl:ENSMUST00000165365(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4I0K|refseq:NP_598744.1|dip:DIP-60156N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:K0P7V23+ODgsXh44SWJHnGQ4cQo10090	rogid:K0P7V23+ODgsXh44SWJHnGQ4cQo10090	rigid:rDqyyxMOoDjNhEFf5EF6Iy4p3wY	false	sufficient binding region:34-247|mutation decreasing interaction strength:126-126|mutation disrupting interaction strength:129-129,128-128,127-127,126-126	sufficient binding region:34-247|mutation decreasing interaction strength:126-126|mutation disrupting interaction strength:129-129,128-128,127-127,126-126	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8VE98	uniprotkb:Q8VE98	intact:EBI-16044767|ensembl:ENSMUSP00000042681|ensembl:ENSMUSP00000129418	intact:EBI-16044767|ensembl:ENSMUSP00000042681|ensembl:ENSMUSP00000129418	psi-mi:cd276_mouse(display_long)|uniprotkb:Cd276(gene name)|psi-mi:Cd276(display_short)|uniprotkb:B7h3(gene name synonym)|uniprotkb:B7 homolog 3(gene name synonym)|uniprotkb:Costimulatory molecule(gene name synonym)	psi-mi:cd276_mouse(display_long)|uniprotkb:Cd276(gene name)|psi-mi:Cd276(display_short)|uniprotkb:B7h3(gene name synonym)|uniprotkb:B7 homolog 3(gene name synonym)|uniprotkb:Costimulatory molecule(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Vigdorovich et al. (2013)	pubmed:23583036|doi:10.1016/j.str.2013.03.003|imex:IM-21025	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16044831|imex:IM-21025-2|dip:DIP-190628E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000035914(gene)|ensembl:ENSMUST00000039788(transcript)|ensembl:ENSMUST00000165365(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4I0K|refseq:NP_598744.1|dip:DIP-60156N	ensembl:ENSMUSG00000035914(gene)|ensembl:ENSMUST00000039788(transcript)|ensembl:ENSMUST00000165365(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:4I0K|refseq:NP_598744.1|dip:DIP-60156N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:K0P7V23+ODgsXh44SWJHnGQ4cQo10090	rogid:K0P7V23+ODgsXh44SWJHnGQ4cQo10090	rigid:rDqyyxMOoDjNhEFf5EF6Iy4p3wY	false	sufficient binding region:34-247	sufficient binding region:34-247	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)