#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UNH7 uniprotkb:Q13596 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Niu et al. (2013) pubmed:23524952|doi:10.1038/ncb2710|imex:IM-22381 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16042701|imex:IM-22381-1|dip:DIP-195964E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:teC1VmGYCNr1ihcKvyvebsyHYB0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UNH7 uniprotkb:Q14203 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Niu et al. (2013) pubmed:23524952|doi:10.1038/ncb2710|imex:IM-22381 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16042701|imex:IM-22381-1|dip:DIP-195964E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:teC1VmGYCNr1ihcKvyvebsyHYB0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95219 uniprotkb:Q8IX03-1 intact:EBI-724909|uniprotkb:D3DNA3|uniprotkb:B4DQV4|uniprotkb:B3KMH0|ensembl:ENSP00000251775 intact:EBI-15812469|ensembl:ENSP00000265293 psi-mi:snx4_human(display_long)|uniprotkb:SNX4(gene name)|psi-mi:SNX4(display_short) psi-mi:q8ix03-1(display_long)|uniprotkb:WWC1(gene name)|psi-mi:WWC1(display_short)|uniprotkb:KIAA0869(gene name synonym)|uniprotkb:HBeAg-binding protein 3(gene name synonym)|uniprotkb:Kidney and brain protein(gene name synonym)|uniprotkb:WW domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Niu et al. (2013) pubmed:23524952|doi:10.1038/ncb2710|imex:IM-22381 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16042750|imex:IM-22381-3|dip:DIP-195965E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003785.1|ensembl:ENSG00000114520(gene)|ensembl:ENST00000251775(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1903595"(positive regulation of histamine secretion by mast cell)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR034783|interpro:IPR034902|interpro:IPR036871|interpro:IPR037430|dip:DIP-36719N ensembl:ENSG00000113645(gene)|ensembl:ENST00000265293(transcript)|intact:EBI-715828(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:Y/Dg8VrUYYvI5Xf67D3unhCjLDA9606 rogid:AGllK9/JguvRQEPw79FYfSgPjiU9606 rigid:M7UFF3xrF3VywO2KJpkugjLkTAA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95219 uniprotkb:Q14203 intact:EBI-724909|uniprotkb:D3DNA3|uniprotkb:B4DQV4|uniprotkb:B3KMH0|ensembl:ENSP00000251775 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:snx4_human(display_long)|uniprotkb:SNX4(gene name)|psi-mi:SNX4(display_short) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Niu et al. (2013) pubmed:23524952|doi:10.1038/ncb2710|imex:IM-22381 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16042750|imex:IM-22381-3|dip:DIP-195965E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003785.1|ensembl:ENSG00000114520(gene)|ensembl:ENST00000251775(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:1903595"(positive regulation of histamine secretion by mast cell)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR034783|interpro:IPR034902|interpro:IPR036871|interpro:IPR037430|dip:DIP-36719N refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:Y/Dg8VrUYYvI5Xf67D3unhCjLDA9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:M7UFF3xrF3VywO2KJpkugjLkTAA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UNH7-1 uniprotkb:Q14203 intact:EBI-16042719|ensembl:ENSP00000355217 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:q9unh7-1(display_long)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short)|uniprotkb:TRAF4-associated factor 2(gene name synonym) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Niu et al. (2013) pubmed:23524952|doi:10.1038/ncb2710|imex:IM-22381 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042725|imex:IM-22381-2|dip:DIP-195963E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|intact:EBI-949294(isoform-parent) refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:iSNJKOaKXPwRme4/BL0ALCXUO/I false sufficient binding region:1-181|flag tag:?-? myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UNH7 uniprotkb:Q14203 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 intact:EBI-724352|uniprotkb:O95296|uniprotkb:Q9BRM9|uniprotkb:Q9UIU1|intact:EBI-28971695|ensembl:ENSP00000487279|uniprotkb:Q9UIU2|uniprotkb:E9PGE1|uniprotkb:G5E9H4|uniprotkb:Q6IQ37|intact:EBI-2560059|uniprotkb:B4DM45|uniprotkb:E9PFS5|uniprotkb:A8MY36|intact:EBI-10962300 psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:dctn1_human(display_long)|uniprotkb:DCTN1(gene name)|psi-mi:DCTN1(display_short)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:p135(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Niu et al. (2013) pubmed:23524952|doi:10.1038/ncb2710|imex:IM-22381 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042768|imex:IM-22381-4|dip:DIP-195963E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N refseq:NP_001128512.1|refseq:NP_001128513.1|refseq:NP_001177766.1|refseq:NP_004073.2|refseq:NP_075408.1|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381038|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518|reactome:R-HSA-380259|ensembl:ENSG00000204843(gene)|ensembl:ENST00000628224(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007399"(nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048156"(tau protein binding)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:Q14203|rcsb pdb:1TXQ|rcsb pdb:2COY|rcsb pdb:2HKN|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2HQH|rcsb pdb:3E2U|rcsb pdb:3TQ7|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|ensembl:ENST00000394003|ensembl:ENSP00000377571|ensembl:ENST00000409240|ensembl:ENSP00000386406|ensembl:ENST00000409438|ensembl:ENSP00000387270|ensembl:ENST00000409567|ensembl:ENSP00000386843|ensembl:ENSP00000487279|ensembl:ENST00000633691|ensembl:ENSP00000487724|refseq:NP_001177765.1|dip:DIP-31365N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/07 2017/08/10 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rogid:PKchWdLWycCErGzSVMXq/xCQJRM9606 rigid:iSNJKOaKXPwRme4/BL0ALCXUO/I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)