#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q3KNV8-1 uniprotkb:Q5H9F3-1 intact:EBI-16041833|ensembl:ENSP00000354724|ensembl:ENSP00000420489 intact:EBI-16041827 psi-mi:q3knv8-1(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16041842|imex:IM-21017-1|dip:DIP-190614E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2339807(isoform-parent)|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript) intact:EBI-8833946(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rigid:cyTeO/EBU0yC69YTwSVlx0yk9Lw false sufficient binding region:152-242 sufficient binding region:1594-1711 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5H9F3-1 uniprotkb:Q9BSM1-1 intact:EBI-16041827 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0096"(pull down) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16041872|imex:IM-21017-2|dip:DIP-190613E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8833946(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:oKjWppe2X3VkwuC+FQ8YPcl+ilc false sufficient binding region:1594-1711 sufficient binding region:167-255|his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0096"(pull down) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16041897|imex:IM-21017-3|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255|his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16041922|imex:IM-21017-4|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255|mutation disrupting interaction rate:191-191|mutation disrupting interaction rate:193-193|mutation disrupting interaction rate:206-206 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16041952|imex:IM-21017-5|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35227 uniprotkb:P78364 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16041973|imex:IM-21017-6|dip:DIP-190617E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750 refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rigid:ULfeRcPABgSX6qu7lF2yv0QrS9c false sufficient binding region:121-229|mutation decreasing interaction strength:165-165|mutation decreasing interaction strength:164-164|mutation decreasing interaction strength:180-180 sufficient binding region:720-760 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q3KNV8-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041833|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q3knv8-1(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042002|imex:IM-21017-7|dip:DIP-190615E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) intact:EBI-2339807(isoform-parent)|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rigid:3pk/EMykqC5Eu3jM3udZVA+N+zE false sufficient binding region:1634-1748 sufficient binding region:152-242 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5H9F3-1 uniprotkb:Q9BSM1-1 intact:EBI-16041827 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042023|imex:IM-21017-8|dip:DIP-190613E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8833946(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:oKjWppe2X3VkwuC+FQ8YPcl+ilc false sufficient binding region:1594-1711 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35226 uniprotkb:P78364 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042107|imex:IM-21017-12|dip:DIP-190616E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rigid:qq1GdfSaGdH23EceUD28VbHBUSE false sufficient binding region:127-228|mutation decreasing interaction strength:163-163|mutation decreasing interaction strength:165-165|mutation decreasing interaction strength:178-178 sufficient binding region:720-760 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5H9F3-1 uniprotkb:Q9BSM1-1 intact:EBI-16041827 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042086|imex:IM-21017-11|dip:DIP-190613E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8833946(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:oKjWppe2X3VkwuC+FQ8YPcl+ilc false sufficient binding region:1594-1711 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5H9F3-1 uniprotkb:Q9BSM1-1 intact:EBI-16041827 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042065|imex:IM-21017-10|dip:DIP-190613E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8833946(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:oKjWppe2X3VkwuC+FQ8YPcl+ilc false sufficient binding region:1594-1711 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042044|imex:IM-21017-9|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042158|imex:IM-21017-14|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042137|imex:IM-21017-13|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5H9F3-1 uniprotkb:Q9BSM1-1 intact:EBI-16041827 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042180|imex:IM-21017-15|dip:DIP-190613E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8833946(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:oKjWppe2X3VkwuC+FQ8YPcl+ilc false sufficient binding region:1594-1711 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6W2J9-1 uniprotkb:Q9BSM1-1 intact:EBI-16028932|ensembl:ENSP00000367705|ensembl:ENSP00000384485|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q6w2j9-1(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym)|uniprotkb:Long(isoform synonym) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16042202|imex:IM-21017-16|dip:DIP-190612E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|intact:EBI-950027(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false sufficient binding region:1634-1748 sufficient binding region:167-255 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5H9F3-1 uniprotkb:Q9BSM1-1 intact:EBI-16041827 intact:EBI-16041863|ensembl:ENSP00000233630 psi-mi:q5h9f3-1(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:q9bsm1-1(display_long)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042223|imex:IM-21017-17|dip:DIP-190613E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8833946(isoform-parent) ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|intact:EBI-749901(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:oKjWppe2X3VkwuC+FQ8YPcl+ilc false sufficient binding region:1594-1711 sufficient binding region:167-255|mutation disrupting interaction rate:191-191|mutation disrupting interaction rate:193-193|mutation disrupting interaction rate:206-206 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95931 uniprotkb:Q99496 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0655"(lambda repressor two hybrid) Junco et al. (2013) pubmed:23523425|doi:10.1016/j.str.2013.02.013|imex:IM-21017 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16042253|imex:IM-21017-18|dip:DIP-103293E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:WlpYB+jNgCfUOkQ9lgCDug4xKLw false sufficient binding region:211-251 sufficient binding region:222-336 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)