#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P24182 uniprotkb:P0ABD8 intact:EBI-542308|uniprotkb:Q2M8V9|ensemblbacteria:AAC76288|ensemblbacteria:BAE77297 intact:EBI-542320|uniprotkb:P02905|ensemblbacteria:AAC76287|ensemblbacteria:BAE77296|uniprotkb:Q2M8W0 psi-mi:accc_ecoli(display_long)|uniprotkb:accC(gene name)|psi-mi:accC(display_short)|uniprotkb:fabG(gene name synonym)|uniprotkb:b3256(locus name)|uniprotkb:Acetyl-CoA carboxylase subunit A(gene name synonym)|uniprotkb:JW3224(locus name) psi-mi:bccp_ecoli(display_long)|uniprotkb:accB(gene name)|psi-mi:accB(display_short)|uniprotkb:fabE(gene name synonym)|uniprotkb:b3255(locus name)|uniprotkb:JW3223(locus name) psi-mi:"MI:0096"(pull down) Broussard et al. (2013) pubmed:23499019|doi:10.1016/j.str.2013.02.001|imex:IM-21014 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16040754|imex:IM-21014-1|dip:DIP-101946E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417722.1|refseq:WP_000884639.1|ensemblbacteria:AAC76288(transcript)|ensemblbacteria:b3256(gene)|ensemblbacteria:BAE77297(gene)|ensemblbacteria:BAE77297(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR004549(Acetyl-CoA carboxylase, biotin carboxylase)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:1BNC|rcsb pdb:1DV1|rcsb pdb:1DV2|rcsb pdb:1K69|rcsb pdb:2GPS|rcsb pdb:2GPW|rcsb pdb:2J9G|rcsb pdb:2V58|rcsb pdb:2V59|rcsb pdb:2V5A|rcsb pdb:2VR1|rcsb pdb:2W6M|rcsb pdb:2W6N|rcsb pdb:2W6O|rcsb pdb:2W6P|rcsb pdb:2W6Q|rcsb pdb:2W6Z|rcsb pdb:2W70|rcsb pdb:2W71|rcsb pdb:3G8C|rcsb pdb:3G8D|rcsb pdb:3JZF|rcsb pdb:3JZI|rcsb pdb:3RUP|rcsb pdb:3RV3|rcsb pdb:3RV4|rcsb pdb:4HR7|rcsb pdb:6OI9|go:"GO:0006633"(fatty acid biosynthetic process)|dip:DIP-9035N ensemblbacteria:AAC76287(transcript)|ensemblbacteria:b3255(gene)|ensemblbacteria:BAE77296(gene)|ensemblbacteria:BAE77296(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009305"(protein biotinylation)|go:"GO:0009317"(acetyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001249(Acetyl-CoA biotin carboxyl carrier)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011053(Single hybrid motif)|rcsb pdb:1A6X|rcsb pdb:1BDO|refseq:NP_417721.1|rcsb pdb:1K67|rcsb pdb:1K69|rcsb pdb:2BDO|rcsb pdb:3BDO|rcsb pdb:4HR7|refseq:WP_000354622.1|dip:DIP-48007N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:HaIU1fGCBPTwS+MbXHO7nwk7PTg83333 rogid:ACVnJAd0Fv/98UHZckojvPKVMOY83333 rigid:zvuRp0AS8mvjcWzlCHIu44c4epg false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24182 uniprotkb:P0ABD8 intact:EBI-542308|uniprotkb:Q2M8V9|ensemblbacteria:AAC76288|ensemblbacteria:BAE77297 intact:EBI-542320|uniprotkb:P02905|ensemblbacteria:AAC76287|ensemblbacteria:BAE77296|uniprotkb:Q2M8W0 psi-mi:accc_ecoli(display_long)|uniprotkb:accC(gene name)|psi-mi:accC(display_short)|uniprotkb:fabG(gene name synonym)|uniprotkb:b3256(locus name)|uniprotkb:Acetyl-CoA carboxylase subunit A(gene name synonym)|uniprotkb:JW3224(locus name) psi-mi:bccp_ecoli(display_long)|uniprotkb:accB(gene name)|psi-mi:accB(display_short)|uniprotkb:fabE(gene name synonym)|uniprotkb:b3255(locus name)|uniprotkb:JW3223(locus name) psi-mi:"MI:0071"(molecular sieving) Broussard et al. (2013) pubmed:23499019|doi:10.1016/j.str.2013.02.001|imex:IM-21014 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16040773|imex:IM-21014-2|dip:DIP-101946E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417722.1|refseq:WP_000884639.1|ensemblbacteria:AAC76288(transcript)|ensemblbacteria:b3256(gene)|ensemblbacteria:BAE77297(gene)|ensemblbacteria:BAE77297(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR004549(Acetyl-CoA carboxylase, biotin carboxylase)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:1BNC|rcsb pdb:1DV1|rcsb pdb:1DV2|rcsb pdb:1K69|rcsb pdb:2GPS|rcsb pdb:2GPW|rcsb pdb:2J9G|rcsb pdb:2V58|rcsb pdb:2V59|rcsb pdb:2V5A|rcsb pdb:2VR1|rcsb pdb:2W6M|rcsb pdb:2W6N|rcsb pdb:2W6O|rcsb pdb:2W6P|rcsb pdb:2W6Q|rcsb pdb:2W6Z|rcsb pdb:2W70|rcsb pdb:2W71|rcsb pdb:3G8C|rcsb pdb:3G8D|rcsb pdb:3JZF|rcsb pdb:3JZI|rcsb pdb:3RUP|rcsb pdb:3RV3|rcsb pdb:3RV4|rcsb pdb:4HR7|rcsb pdb:6OI9|go:"GO:0006633"(fatty acid biosynthetic process)|dip:DIP-9035N ensemblbacteria:AAC76287(transcript)|ensemblbacteria:b3255(gene)|ensemblbacteria:BAE77296(gene)|ensemblbacteria:BAE77296(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009305"(protein biotinylation)|go:"GO:0009317"(acetyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001249(Acetyl-CoA biotin carboxyl carrier)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011053(Single hybrid motif)|rcsb pdb:1A6X|rcsb pdb:1BDO|refseq:NP_417721.1|rcsb pdb:1K67|rcsb pdb:1K69|rcsb pdb:2BDO|rcsb pdb:3BDO|rcsb pdb:4HR7|refseq:WP_000354622.1|dip:DIP-48007N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:HaIU1fGCBPTwS+MbXHO7nwk7PTg83333 rogid:ACVnJAd0Fv/98UHZckojvPKVMOY83333 rigid:zvuRp0AS8mvjcWzlCHIu44c4epg false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P24182 uniprotkb:P0ABD8 intact:EBI-542308|uniprotkb:Q2M8V9|ensemblbacteria:AAC76288|ensemblbacteria:BAE77297 intact:EBI-542320|uniprotkb:P02905|ensemblbacteria:AAC76287|ensemblbacteria:BAE77296|uniprotkb:Q2M8W0 psi-mi:accc_ecoli(display_long)|uniprotkb:accC(gene name)|psi-mi:accC(display_short)|uniprotkb:fabG(gene name synonym)|uniprotkb:b3256(locus name)|uniprotkb:Acetyl-CoA carboxylase subunit A(gene name synonym)|uniprotkb:JW3224(locus name) psi-mi:bccp_ecoli(display_long)|uniprotkb:accB(gene name)|psi-mi:accB(display_short)|uniprotkb:fabE(gene name synonym)|uniprotkb:b3255(locus name)|uniprotkb:JW3223(locus name) psi-mi:"MI:0114"(x-ray crystallography) Broussard et al. (2013) pubmed:23499019|doi:10.1016/j.str.2013.02.001|imex:IM-21014 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16040791|imex:IM-21014-3|dip:DIP-101946E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_417722.1|refseq:WP_000884639.1|ensemblbacteria:AAC76288(transcript)|ensemblbacteria:b3256(gene)|ensemblbacteria:BAE77297(gene)|ensemblbacteria:BAE77297(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR004549(Acetyl-CoA carboxylase, biotin carboxylase)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:1BNC|rcsb pdb:1DV1|rcsb pdb:1DV2|rcsb pdb:1K69|rcsb pdb:2GPS|rcsb pdb:2GPW|rcsb pdb:2J9G|rcsb pdb:2V58|rcsb pdb:2V59|rcsb pdb:2V5A|rcsb pdb:2VR1|rcsb pdb:2W6M|rcsb pdb:2W6N|rcsb pdb:2W6O|rcsb pdb:2W6P|rcsb pdb:2W6Q|rcsb pdb:2W6Z|rcsb pdb:2W70|rcsb pdb:2W71|rcsb pdb:3G8C|rcsb pdb:3G8D|rcsb pdb:3JZF|rcsb pdb:3JZI|rcsb pdb:3RUP|rcsb pdb:3RV3|rcsb pdb:3RV4|rcsb pdb:4HR7|rcsb pdb:6OI9|go:"GO:0006633"(fatty acid biosynthetic process)|dip:DIP-9035N ensemblbacteria:AAC76287(transcript)|ensemblbacteria:b3255(gene)|ensemblbacteria:BAE77296(gene)|ensemblbacteria:BAE77296(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0009305"(protein biotinylation)|go:"GO:0009317"(acetyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001249(Acetyl-CoA biotin carboxyl carrier)|interpro:IPR001882(Biotin-binding site)|interpro:IPR011053(Single hybrid motif)|rcsb pdb:1A6X|rcsb pdb:1BDO|refseq:NP_417721.1|rcsb pdb:1K67|rcsb pdb:1K69|rcsb pdb:2BDO|rcsb pdb:3BDO|rcsb pdb:4HR7|refseq:WP_000354622.1|dip:DIP-48007N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:HaIU1fGCBPTwS+MbXHO7nwk7PTg83333 rogid:ACVnJAd0Fv/98UHZckojvPKVMOY83333 rigid:zvuRp0AS8mvjcWzlCHIu44c4epg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)