#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q62074	uniprotkb:Q8R1S4	intact:EBI-82016|ensembl:ENSMUSP00000103884	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	psi-mi:kpci_mouse(display_long)|uniprotkb:Prkci(gene name)|psi-mi:Prkci(display_short)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:Pkcl(gene name synonym)	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038782|imex:IM-20782-1|dip:DIP-190516E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032883.2|ensembl:ENSMUSG00000037643(gene)|ensembl:ENSMUST00000108249(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:Q62074|rcsb pdb:4DC2|reactome:R-MMU-1912408|reactome:R-MMU-209543|reactome:R-MMU-420029|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|dip:DIP-32555N	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:9q8JyZjufAVMLR0+uIK7y4nD9dI10090	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rigid:l9Big1vHjIcNkNCg68tPkkwAKPI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8R1S4	uniprotkb:Q9Z101	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	intact:EBI-81732|uniprotkb:Q5RL03|uniprotkb:Q6P8R2|ensembl:ENSMUSP00000090886	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:par6a_mouse(display_long)|uniprotkb:Pard6a(gene name)|psi-mi:Pard6a(display_short)|uniprotkb:Par6a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038833|imex:IM-20782-3|dip:DIP-190515E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	refseq:NP_001040900.1|refseq:NP_062669.2|ensembl:ENSMUSG00000005699(gene)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSMUST00000093195(transcript)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR034868|interpro:IPR034872|interpro:IPR036034|reactome:R-MMU-2173791|reactome:R-MMU-420029|reactome:R-MMU-4608870|reactome:R-MMU-9013148|reactome:R-MMU-9013149|dip:DIP-32553N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rogid:gmmbxc9dNybdFr3Tf6e8lN5H/vQ10090	rigid:AL66MLkv3IR+3KyWYsyYAo2iEIE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8R1S4	uniprotkb:Q99NH2-1	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	intact:EBI-15946047	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:q99nh2-1(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:180 kDa(isoform synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Ephrin-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038833|imex:IM-20782-3|dip:DIP-190515E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	intact:EBI-6299697(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rogid:T32+accBUmq14vv2OXj2mZe9fzQ10090	rigid:AL66MLkv3IR+3KyWYsyYAo2iEIE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8R1S4	uniprotkb:Q62074	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	intact:EBI-82016|ensembl:ENSMUSP00000103884	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:kpci_mouse(display_long)|uniprotkb:Prkci(gene name)|psi-mi:Prkci(display_short)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:Pkcl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038833|imex:IM-20782-3|dip:DIP-190515E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	refseq:NP_032883.2|ensembl:ENSMUSG00000037643(gene)|ensembl:ENSMUST00000108249(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:Q62074|rcsb pdb:4DC2|reactome:R-MMU-1912408|reactome:R-MMU-209543|reactome:R-MMU-420029|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|dip:DIP-32555N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rogid:9q8JyZjufAVMLR0+uIK7y4nD9dI10090	rigid:AL66MLkv3IR+3KyWYsyYAo2iEIE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41743	uniprotkb:P08151-1	intact:EBI-286199|uniprotkb:Q8WW06|uniprotkb:D3DNQ4|ensembl:ENSP00000295797	intact:EBI-16038799|ensembl:ENSP00000228682	psi-mi:kpci_human(display_long)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:PRKCI(gene name)|psi-mi:PRKCI(display_short)|uniprotkb:DXS1179E(gene name synonym)	psi-mi:p08151-1(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038808|imex:IM-20782-2|dip:DIP-190518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002731.4|dip:DIP-31311N|ensembl:ENSG00000163558(gene)|ensembl:ENST00000295797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0046903"(secretion)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:P41743|rcsb pdb:1VD2|rcsb pdb:1WMH|rcsb pdb:1ZRZ|rcsb pdb:3A8W|rcsb pdb:3A8X|rcsb pdb:3ZH8|rcsb pdb:5LI1|rcsb pdb:5LI9|rcsb pdb:5LIH|rcsb pdb:6ILZ|reactome:R-HSA-1912408|reactome:R-HSA-209543|reactome:R-HSA-420029	ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|intact:EBI-308084(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:v8sZdKjtlBejk0MH/9gwOjRqy+49606	rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606	rigid:6JTpNkJyjX3SjhiWLgBAKQ14pkc	false	his tag:n-n	sufficient binding region:227-398|ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q62074	uniprotkb:Q8R1S4	intact:EBI-82016|ensembl:ENSMUSP00000103884	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	psi-mi:kpci_mouse(display_long)|uniprotkb:Prkci(gene name)|psi-mi:Prkci(display_short)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:Pkcl(gene name synonym)	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038915|imex:IM-20782-7|dip:DIP-190516E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032883.2|ensembl:ENSMUSG00000037643(gene)|ensembl:ENSMUST00000108249(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:Q62074|rcsb pdb:4DC2|reactome:R-MMU-1912408|reactome:R-MMU-209543|reactome:R-MMU-420029|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|dip:DIP-32555N	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:9q8JyZjufAVMLR0+uIK7y4nD9dI10090	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rigid:l9Big1vHjIcNkNCg68tPkkwAKPI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62074	uniprotkb:Q8R1S4	intact:EBI-82016|ensembl:ENSMUSP00000103884	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	psi-mi:kpci_mouse(display_long)|uniprotkb:Prkci(gene name)|psi-mi:Prkci(display_short)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:Pkcl(gene name synonym)	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038898|imex:IM-20782-6|dip:DIP-190516E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032883.2|ensembl:ENSMUSG00000037643(gene)|ensembl:ENSMUST00000108249(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:Q62074|rcsb pdb:4DC2|reactome:R-MMU-1912408|reactome:R-MMU-209543|reactome:R-MMU-420029|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|dip:DIP-32555N	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:9q8JyZjufAVMLR0+uIK7y4nD9dI10090	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rigid:l9Big1vHjIcNkNCg68tPkkwAKPI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41743	uniprotkb:P08151-1	intact:EBI-286199|uniprotkb:Q8WW06|uniprotkb:D3DNQ4|ensembl:ENSP00000295797	intact:EBI-16038799|ensembl:ENSP00000228682	psi-mi:kpci_human(display_long)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:PRKCI(gene name)|psi-mi:PRKCI(display_short)|uniprotkb:DXS1179E(gene name synonym)	psi-mi:p08151-1(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038869|imex:IM-20782-5|dip:DIP-190518E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002731.4|dip:DIP-31311N|ensembl:ENSG00000163558(gene)|ensembl:ENST00000295797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0046903"(secretion)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:P41743|rcsb pdb:1VD2|rcsb pdb:1WMH|rcsb pdb:1ZRZ|rcsb pdb:3A8W|rcsb pdb:3A8X|rcsb pdb:3ZH8|rcsb pdb:5LI1|rcsb pdb:5LI9|rcsb pdb:5LIH|rcsb pdb:6ILZ|reactome:R-HSA-1912408|reactome:R-HSA-209543|reactome:R-HSA-420029	ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|intact:EBI-308084(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:v8sZdKjtlBejk0MH/9gwOjRqy+49606	rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606	rigid:6JTpNkJyjX3SjhiWLgBAKQ14pkc	false	his tag:n-n	sufficient binding region:227-398|glutathione s tranferase tag:?-?|mutation decreasing interaction rate:304-304,243-243	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99NH2-1	uniprotkb:Q8R1S4	intact:EBI-15946047	intact:EBI-15622277|uniprotkb:Q8BMM3|uniprotkb:Q99LB3	psi-mi:q99nh2-1(display_long)|uniprotkb:Pard3(gene name)|psi-mi:Pard3(display_short)|uniprotkb:Par3(gene name synonym)|uniprotkb:180 kDa(isoform synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:Ephrin-interacting protein(gene name synonym)	psi-mi:mtss1_mouse(display_long)|uniprotkb:Mtss1(gene name)|psi-mi:Mtss1(display_short)|uniprotkb:Mim(gene name synonym)|uniprotkb:Missing in metastasis protein(gene name synonym)|uniprotkb:Metastasis suppressor protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038852|imex:IM-20782-4|dip:DIP-190517E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-6299697(isoform-parent)	go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030282"(bone mineralization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061333"(renal tubule morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0072160"(nephron tubule epithelial cell differentiation)|go:"GO:0072170"(metanephric tubule development)|go:"GO:2001013"(epithelial cell proliferation involved in renal tubule morphogenesis)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027682|interpro:IPR030127|rcsb pdb:2D1L|refseq:NP_659049.2|dip:DIP-29271N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:T32+accBUmq14vv2OXj2mZe9fzQ10090	rogid:N7Om4JSlgLfJQJfgB/iMVE6oLG810090	rigid:1rJtEivsM+Tamb/oafYrsn3Jz98	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41743	uniprotkb:P08151-1	intact:EBI-286199|uniprotkb:Q8WW06|uniprotkb:D3DNQ4|ensembl:ENSP00000295797	intact:EBI-16038799|ensembl:ENSP00000228682	psi-mi:kpci_human(display_long)|uniprotkb:nPKC-iota(gene name synonym)|uniprotkb:Atypical protein kinase C-lambda/iota(gene name synonym)|uniprotkb:PRKCI(gene name)|psi-mi:PRKCI(display_short)|uniprotkb:DXS1179E(gene name synonym)	psi-mi:p08151-1(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Atwood et al. (2013)	pubmed:23446420|doi:10.1038/nature11889|imex:IM-20782	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038932|imex:IM-20782-8|dip:DIP-190518E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002731.4|dip:DIP-31311N|ensembl:ENSG00000163558(gene)|ensembl:ENST00000295797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031252"(cell leading edge)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0046903"(secretion)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012233(Protein kinase C, zeta/iota)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034661|interpro:IPR034877|mint:P41743|rcsb pdb:1VD2|rcsb pdb:1WMH|rcsb pdb:1ZRZ|rcsb pdb:3A8W|rcsb pdb:3A8X|rcsb pdb:3ZH8|rcsb pdb:5LI1|rcsb pdb:5LI9|rcsb pdb:5LIH|rcsb pdb:6ILZ|reactome:R-HSA-1912408|reactome:R-HSA-209543|reactome:R-HSA-420029	ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|intact:EBI-308084(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:v8sZdKjtlBejk0MH/9gwOjRqy+49606	rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606	rigid:6JTpNkJyjX3SjhiWLgBAKQ14pkc	false	his tag:n-n	sufficient binding region:227-398|ha tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)