#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07700	uniprotkb:P07700	intact:EBI-16038126	intact:EBI-16038126	psi-mi:adrb1_melga(display_long)|uniprotkb:ADRB1(gene name)|psi-mi:ADRB1(display_short)|uniprotkb:Beta-1 adrenoreceptor(gene name synonym)	psi-mi:adrb1_melga(display_long)|uniprotkb:ADRB1(gene name)|psi-mi:ADRB1(display_short)|uniprotkb:Beta-1 adrenoreceptor(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Huang et al. (2013)	pubmed:23435379|doi:10.1038/nsmb.2504|imex:IM-21113	taxid:9103(melga)|taxid:9103("Meleagris gallopavo (Common turkey)")	taxid:9103(melga)|taxid:9103("Meleagris gallopavo (Common turkey)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038172|imex:IM-21113-1|dip:DIP-190986E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004940"(beta1-adrenergic receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000507(Adrenergic receptor, beta 1)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1DEP|rcsb pdb:2VT4|rcsb pdb:2Y00|rcsb pdb:2Y01|rcsb pdb:2Y02|rcsb pdb:2Y03|rcsb pdb:2Y04|rcsb pdb:2YCW|rcsb pdb:2YCX|rcsb pdb:2YCY|rcsb pdb:2YCZ|rcsb pdb:3ZPQ|rcsb pdb:3ZPR|rcsb pdb:4AMI|rcsb pdb:4AMJ|rcsb pdb:4BVN|rcsb pdb:4GPO|rcsb pdb:5A8E|rcsb pdb:5F8U|go:"GO:0005886"(plasma membrane)|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6TKO|rcsb pdb:7JJO|refseq:NP_001290104.1|dip:DIP-60236N	go:"GO:0004940"(beta1-adrenergic receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000507(Adrenergic receptor, beta 1)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1DEP|rcsb pdb:2VT4|rcsb pdb:2Y00|rcsb pdb:2Y01|rcsb pdb:2Y02|rcsb pdb:2Y03|rcsb pdb:2Y04|rcsb pdb:2YCW|rcsb pdb:2YCX|rcsb pdb:2YCY|rcsb pdb:2YCZ|rcsb pdb:3ZPQ|rcsb pdb:3ZPR|rcsb pdb:4AMI|rcsb pdb:4AMJ|rcsb pdb:4BVN|rcsb pdb:4GPO|rcsb pdb:5A8E|rcsb pdb:5F8U|go:"GO:0005886"(plasma membrane)|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6TKO|rcsb pdb:7JJO|refseq:NP_001290104.1|dip:DIP-60236N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/07	2017/08/10	rogid:SsUkmZdcUFmTSzGO0vuA2NSe94w9103	rogid:SsUkmZdcUFmTSzGO0vuA2NSe94w9103	rigid:auAh8zHAszoP8N/nkFDNzFNKg0w	false	sufficient binding region:33-243,272-365	sufficient binding region:33-243,272-365	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07700	uniprotkb:P07700	intact:EBI-16038126	intact:EBI-16038126	psi-mi:adrb1_melga(display_long)|uniprotkb:ADRB1(gene name)|psi-mi:ADRB1(display_short)|uniprotkb:Beta-1 adrenoreceptor(gene name synonym)	psi-mi:adrb1_melga(display_long)|uniprotkb:ADRB1(gene name)|psi-mi:ADRB1(display_short)|uniprotkb:Beta-1 adrenoreceptor(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Huang et al. (2013)	pubmed:23435379|doi:10.1038/nsmb.2504|imex:IM-21113	taxid:9103(melga)|taxid:9103("Meleagris gallopavo (Common turkey)")	taxid:9103(melga)|taxid:9103("Meleagris gallopavo (Common turkey)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038191|imex:IM-21113-2|dip:DIP-190986E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004940"(beta1-adrenergic receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000507(Adrenergic receptor, beta 1)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1DEP|rcsb pdb:2VT4|rcsb pdb:2Y00|rcsb pdb:2Y01|rcsb pdb:2Y02|rcsb pdb:2Y03|rcsb pdb:2Y04|rcsb pdb:2YCW|rcsb pdb:2YCX|rcsb pdb:2YCY|rcsb pdb:2YCZ|rcsb pdb:3ZPQ|rcsb pdb:3ZPR|rcsb pdb:4AMI|rcsb pdb:4AMJ|rcsb pdb:4BVN|rcsb pdb:4GPO|rcsb pdb:5A8E|rcsb pdb:5F8U|go:"GO:0005886"(plasma membrane)|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6TKO|rcsb pdb:7JJO|refseq:NP_001290104.1|dip:DIP-60236N	go:"GO:0004940"(beta1-adrenergic receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000507(Adrenergic receptor, beta 1)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1DEP|rcsb pdb:2VT4|rcsb pdb:2Y00|rcsb pdb:2Y01|rcsb pdb:2Y02|rcsb pdb:2Y03|rcsb pdb:2Y04|rcsb pdb:2YCW|rcsb pdb:2YCX|rcsb pdb:2YCY|rcsb pdb:2YCZ|rcsb pdb:3ZPQ|rcsb pdb:3ZPR|rcsb pdb:4AMI|rcsb pdb:4AMJ|rcsb pdb:4BVN|rcsb pdb:4GPO|rcsb pdb:5A8E|rcsb pdb:5F8U|go:"GO:0005886"(plasma membrane)|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6TKO|rcsb pdb:7JJO|refseq:NP_001290104.1|dip:DIP-60236N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/07	2017/08/10	rogid:SsUkmZdcUFmTSzGO0vuA2NSe94w9103	rogid:SsUkmZdcUFmTSzGO0vuA2NSe94w9103	rigid:auAh8zHAszoP8N/nkFDNzFNKg0w	false	sufficient binding region:33-248,284-365|mutation:148-148	sufficient binding region:33-248,284-365|mutation:148-148	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P07700	uniprotkb:P07700	intact:EBI-16038126	intact:EBI-16038126	psi-mi:adrb1_melga(display_long)|uniprotkb:ADRB1(gene name)|psi-mi:ADRB1(display_short)|uniprotkb:Beta-1 adrenoreceptor(gene name synonym)	psi-mi:adrb1_melga(display_long)|uniprotkb:ADRB1(gene name)|psi-mi:ADRB1(display_short)|uniprotkb:Beta-1 adrenoreceptor(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Huang et al. (2013)	pubmed:23435379|doi:10.1038/nsmb.2504|imex:IM-21113	taxid:9103(melga)|taxid:9103("Meleagris gallopavo (Common turkey)")	taxid:9103(melga)|taxid:9103("Meleagris gallopavo (Common turkey)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16038213|imex:IM-21113-3|dip:DIP-190986E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004940"(beta1-adrenergic receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000507(Adrenergic receptor, beta 1)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1DEP|rcsb pdb:2VT4|rcsb pdb:2Y00|rcsb pdb:2Y01|rcsb pdb:2Y02|rcsb pdb:2Y03|rcsb pdb:2Y04|rcsb pdb:2YCW|rcsb pdb:2YCX|rcsb pdb:2YCY|rcsb pdb:2YCZ|rcsb pdb:3ZPQ|rcsb pdb:3ZPR|rcsb pdb:4AMI|rcsb pdb:4AMJ|rcsb pdb:4BVN|rcsb pdb:4GPO|rcsb pdb:5A8E|rcsb pdb:5F8U|go:"GO:0005886"(plasma membrane)|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6TKO|rcsb pdb:7JJO|refseq:NP_001290104.1|dip:DIP-60236N	go:"GO:0004940"(beta1-adrenergic receptor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000507(Adrenergic receptor, beta 1)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:1DEP|rcsb pdb:2VT4|rcsb pdb:2Y00|rcsb pdb:2Y01|rcsb pdb:2Y02|rcsb pdb:2Y03|rcsb pdb:2Y04|rcsb pdb:2YCW|rcsb pdb:2YCX|rcsb pdb:2YCY|rcsb pdb:2YCZ|rcsb pdb:3ZPQ|rcsb pdb:3ZPR|rcsb pdb:4AMI|rcsb pdb:4AMJ|rcsb pdb:4BVN|rcsb pdb:4GPO|rcsb pdb:5A8E|rcsb pdb:5F8U|go:"GO:0005886"(plasma membrane)|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6TKO|rcsb pdb:7JJO|refseq:NP_001290104.1|dip:DIP-60236N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/07	2017/08/10	rogid:SsUkmZdcUFmTSzGO0vuA2NSe94w9103	rogid:SsUkmZdcUFmTSzGO0vuA2NSe94w9103	rigid:auAh8zHAszoP8N/nkFDNzFNKg0w	false	sufficient binding region:33-248,284-365|mutation:354-354	sufficient binding region:33-248,284-365|mutation:354-354	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)