#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P26231 uniprotkb:P26231 intact:EBI-647895|ensembl:ENSMUSP00000049007 intact:EBI-647895|ensembl:ENSMUSP00000049007 psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym) psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym) psi-mi:"MI:0067"(light scattering) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16036990|imex:IM-22384-3|dip:DIP-195988E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467 refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090 rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090 rigid:sSxnhCIvezrHcOOFupvEhtR+jJY false sufficient binding region:58-906 sufficient binding region:58-906 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35220 uniprotkb:P35220 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0071"(molecular sieving) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16036972|imex:IM-22384-2|dip:DIP-195987E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:xGbOtpMe49LbaF6V9vwmQinvpQ4 false sufficient binding region:65-917 sufficient binding region:65-917 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18824 uniprotkb:P35220 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16036950|imex:IM-22384-1|dip:DIP-68102E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - comment:Deletion of region 398-509 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:znIt5ScdiMpbU67N9XG7mqiTP5g false - necessary binding region:1-233|ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35220 uniprotkb:P35220 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0067"(light scattering) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16037069|imex:IM-22384-7|dip:DIP-195987E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:xGbOtpMe49LbaF6V9vwmQinvpQ4 false sufficient binding region:65-917 sufficient binding region:65-917 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68135 uniprotkb:P35220 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16037087|imex:IM-22384-8|dip:DIP-195986E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:CJ87ASdX09ariYTcOaB9J9P2wZY false - sufficient binding region:659-917 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P26231 uniprotkb:P26231 intact:EBI-647895|ensembl:ENSMUSP00000049007 intact:EBI-647895|ensembl:ENSMUSP00000049007 psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym) psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16037106|imex:IM-22384-9|dip:DIP-195988E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467 refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090 rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090 rigid:sSxnhCIvezrHcOOFupvEhtR+jJY false sufficient binding region:58-906 sufficient binding region:58-906 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18824 uniprotkb:P35220 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16037049|imex:IM-22384-6|dip:DIP-68102E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:znIt5ScdiMpbU67N9XG7mqiTP5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18824 uniprotkb:P35220 intact:EBI-216128|uniprotkb:A4V3V0|uniprotkb:O02371|uniprotkb:Q0KHX2|uniprotkb:Q8IRW7|uniprotkb:Q9W546|ensemblmetazoa:FBpp0089031|ensemblmetazoa:FBpp0089032|ensemblmetazoa:FBpp0089034|ensemblmetazoa:FBpp0089035|ensemblmetazoa:FBpp0304835 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:arm_drome(display_long)|uniprotkb:arm(gene name)|psi-mi:arm(display_short)|uniprotkb:CG11579(orf name) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16037049|imex:IM-22384-6|dip:DIP-68102E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476665.2|refseq:NP_476666.1|refseq:NP_599100.1|refseq:NP_726775.2|refseq:NP_996328.1|flybase:FBgn0000117|refseq:NP_001259149.1|dip:DIP-19968N|ensemblmetazoa:FBgn0000117(gene)|ensemblmetazoa:FBtr0089988(transcript)|ensemblmetazoa:FBtr0089989(transcript)|ensemblmetazoa:FBtr0089991(transcript)|ensemblmetazoa:FBtr0089992(transcript)|ensemblmetazoa:FBtr0332583(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001709"(cell fate determination)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007155"(cell adhesion)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007391"(dorsal closure)|go:"GO:0007399"(nervous system development)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0014017"(neuroblast fate commitment)|go:"GO:0014019"(neuroblast development)|go:"GO:0016028"(rhabdomere)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035153"(epithelial cell type specification, open tracheal system)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0046667"(compound eye retinal cell programmed cell death)|go:"GO:0048477"(oogenesis)|go:"GO:0048526"(imaginal disc-derived wing expansion)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060232"(delamination)|go:"GO:0060250"(germ-line stem-cell niche homeostasis)|go:"GO:0060914"(heart formation)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P18824|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-201681|reactome:R-DME-201722|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209407|reactome:R-DME-209413|reactome:R-DME-209421|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3134973|reactome:R-DME-351906|reactome:R-DME-3769402|reactome:R-DME-4086398|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|reactome:R-DME-6798695|reactome:R-DME-8853884|reactome:R-DME-8951430|reactome:R-DME-8980692|reactome:R-DME-9013406|reactome:R-DME-9013407 ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:ICcnVEVmwr7VAp5+5AATqvGwM4k7227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:znIt5ScdiMpbU67N9XG7mqiTP5g false - green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q61301 uniprotkb:Q61301 intact:EBI-774089|uniprotkb:Q61300|uniprotkb:Q6AXD1|uniprotkb:Q3TY37|ensembl:ENSMUSP00000124376 intact:EBI-774089|uniprotkb:Q61300|uniprotkb:Q6AXD1|uniprotkb:Q3TY37|ensembl:ENSMUSP00000124376 psi-mi:ctna2_mouse(display_long)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Ctnna2(gene name)|psi-mi:Ctnna2(display_short)|uniprotkb:Catna2(gene name synonym) psi-mi:ctna2_mouse(display_long)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Ctnna2(gene name)|psi-mi:Ctnna2(display_short)|uniprotkb:Catna2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16037031|imex:IM-22384-5|dip:DIP-195989E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103234.1|refseq:NP_033949.2|refseq:NP_663785.2|dip:DIP-31971N|refseq:XP_011239496.1|refseq:XP_017176861.1|ensembl:ENSMUSG00000063063(gene)|ensembl:ENSMUST00000159626(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|mint:Q61301|rcsb pdb:4K1O|rcsb pdb:4ONS|rcsb pdb:4P9T|rcsb pdb:5XFL|rcsb pdb:6DUY|reactome:R-MMU-525793 refseq:NP_001103234.1|refseq:NP_033949.2|refseq:NP_663785.2|dip:DIP-31971N|refseq:XP_011239496.1|refseq:XP_017176861.1|ensembl:ENSMUSG00000063063(gene)|ensembl:ENSMUST00000159626(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|mint:Q61301|rcsb pdb:4K1O|rcsb pdb:4ONS|rcsb pdb:4P9T|rcsb pdb:5XFL|rcsb pdb:6DUY|reactome:R-MMU-525793 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:0z1O3ZeQwbjZawJfbXvb+dGAWYU10090 rogid:0z1O3ZeQwbjZawJfbXvb+dGAWYU10090 rigid:fJi4cjgTO0+T2ZU4M0zqr1T10Bo false sufficient binding region:58-953 sufficient binding region:58-953 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q24298 uniprotkb:P35220 intact:EBI-112930|uniprotkb:Q9W2N1|ensemblmetazoa:FBpp0071475 intact:EBI-126806|uniprotkb:Q960Y2|uniprotkb:Q9W5V9|ensemblmetazoa:FBpp0070037 psi-mi:cade_drome(display_long)|uniprotkb:shg(gene name)|psi-mi:shg(display_short)|uniprotkb:Protein shotgun(gene name synonym)|uniprotkb:CG3722(orf name)|uniprotkb:E-cadherin(gene name synonym) psi-mi:ctna_drome(display_long)|uniprotkb:alpha-Cat(gene name)|psi-mi:alpha-Cat(display_short)|uniprotkb:CG17947(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16037008|imex:IM-22384-4|dip:DIP-195985E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476722.1|flybase:FBgn0003391|dip:DIP-22198N|ensemblmetazoa:FBgn0003391(gene)|ensemblmetazoa:FBtr0071546(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001748"(insect visual primordium development)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007281"(germ cell development)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0007379"(segment specification)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008258"(head involution)|go:"GO:0008354"(germ cell migration)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0008406"(gonad development)|go:"GO:0010004"(gastrulation involving germ band extension)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035099"(hemocyte migration)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035160"(maintenance of epithelial integrity, open tracheal system)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035262"(gonad morphogenesis)|go:"GO:0036099"(female germ-line stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0050832"(defense response to fungus)|go:"GO:0055037"(recycling endosome)|go:"GO:0071907"(determination of digestive tract left/right asymmetry)|go:"GO:0090254"(cell elongation involved in imaginal disc-derived wing morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098730"(male germline stem cell symmetric division)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397 ensemblmetazoa:FBgn0010215(gene)|ensemblmetazoa:FBtr0070038(transcript)|go:"GO:0003383"(apical constriction)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0051015"(actin filament binding)|go:"GO:0060323"(head morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR036723|reactome:R-DME-418990|reactome:R-DME-5218920|reactome:R-DME-525793|refseq:NP_524219.1|flybase:FBgn0010215|dip:DIP-21662N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2017/08/10 rogid:BEKC07n+twCk47JtwWbhQbw1cs87227 rogid:W6XeVS/IvxqgE0UQ/SyWnAmiJo87227 rigid:5iw5sDNnsgnn5JcgXlBJwTQXwmg false green fluorescent protein tag:c-c ha tag:c-c|necessary binding region:1-233 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q61301 uniprotkb:Q61301 intact:EBI-774089|uniprotkb:Q61300|uniprotkb:Q6AXD1|uniprotkb:Q3TY37|ensembl:ENSMUSP00000124376 intact:EBI-774089|uniprotkb:Q61300|uniprotkb:Q6AXD1|uniprotkb:Q3TY37|ensembl:ENSMUSP00000124376 psi-mi:ctna2_mouse(display_long)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Ctnna2(gene name)|psi-mi:Ctnna2(display_short)|uniprotkb:Catna2(gene name synonym) psi-mi:ctna2_mouse(display_long)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Ctnna2(gene name)|psi-mi:Ctnna2(display_short)|uniprotkb:Catna2(gene name synonym) psi-mi:"MI:0067"(light scattering) Desai et al. (2013) pubmed:23417122|doi:10.1038/ncb2685|imex:IM-22384 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16037124|imex:IM-22384-10|dip:DIP-195989E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103234.1|refseq:NP_033949.2|refseq:NP_663785.2|dip:DIP-31971N|refseq:XP_011239496.1|refseq:XP_017176861.1|ensembl:ENSMUSG00000063063(gene)|ensembl:ENSMUST00000159626(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|mint:Q61301|rcsb pdb:4K1O|rcsb pdb:4ONS|rcsb pdb:4P9T|rcsb pdb:5XFL|rcsb pdb:6DUY|reactome:R-MMU-525793 refseq:NP_001103234.1|refseq:NP_033949.2|refseq:NP_663785.2|dip:DIP-31971N|refseq:XP_011239496.1|refseq:XP_017176861.1|ensembl:ENSMUSG00000063063(gene)|ensembl:ENSMUST00000159626(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|mint:Q61301|rcsb pdb:4K1O|rcsb pdb:4ONS|rcsb pdb:4P9T|rcsb pdb:5XFL|rcsb pdb:6DUY|reactome:R-MMU-525793 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:0z1O3ZeQwbjZawJfbXvb+dGAWYU10090 rogid:0z1O3ZeQwbjZawJfbXvb+dGAWYU10090 rigid:fJi4cjgTO0+T2ZU4M0zqr1T10Bo false sufficient binding region:58-953 sufficient binding region:58-953 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)