#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8U1S7	uniprotkb:Q8U1S6	intact:EBI-2504943|ensemblbacteria:AAL81252	intact:EBI-2504936|ensemblbacteria:AAL81253	psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name)	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16035995|imex:IM-21002-1|dip:DIP-190602E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rigid:8DUPScZqSDtcRg+jUymQiJIjB8A	false	-	sufficient binding region:213-871	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1S7	uniprotkb:Q8U1S6	intact:EBI-2504943|ensemblbacteria:AAL81252	intact:EBI-2504936|ensemblbacteria:AAL81253	psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name)	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:"MI:0096"(pull down)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036035|imex:IM-21002-3|dip:DIP-190602E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rigid:8DUPScZqSDtcRg+jUymQiJIjB8A	false	his tag:n-n	sufficient binding region:213-871|necessary binding region:96-105|necessary binding region:267-277	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q8U1S7	uniprotkb:Q8U1S6	intact:EBI-2504943|ensemblbacteria:AAL81252	intact:EBI-2504936|ensemblbacteria:AAL81253	psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name)	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036060|imex:IM-21002-4|dip:DIP-190602E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rigid:8DUPScZqSDtcRg+jUymQiJIjB8A	false	-	sufficient binding region:213-871	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1S7	uniprotkb:Q8U1S6	intact:EBI-2504943|ensemblbacteria:AAL81252	intact:EBI-2504936|ensemblbacteria:AAL81253	psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name)	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:"MI:0096"(pull down)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036079|imex:IM-21002-5|dip:DIP-190602E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rigid:8DUPScZqSDtcRg+jUymQiJIjB8A	false	-	sufficient binding region:213-871|his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1S5	uniprotkb:Q8U1S6	intact:EBI-2504983|ensemblbacteria:AAL81254	intact:EBI-2504936|ensemblbacteria:AAL81253	psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name)	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036014|imex:IM-21002-2|dip:DIP-136390E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rigid:aIu1ksl/3oa8tv75XagtFUniXOo	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S5	uniprotkb:Q8U1S7	intact:EBI-2504983|ensemblbacteria:AAL81254	intact:EBI-2504943|ensemblbacteria:AAL81252	psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name)	psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036014|imex:IM-21002-2|dip:DIP-136390E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N	ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497	rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497	rigid:aIu1ksl/3oa8tv75XagtFUniXOo	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S5	uniprotkb:Q8U1S9	intact:EBI-2504983|ensemblbacteria:AAL81254	intact:EBI-2504950|ensemblbacteria:AAL81250	psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name)	psi-mi:cmr4_pyrfu(display_long)|uniprotkb:cmr4(gene name)|psi-mi:cmr4(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr4(gene name synonym)|uniprotkb:Target RNase Cmr4(gene name synonym)|uniprotkb:PF1126(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036014|imex:IM-21002-2|dip:DIP-136390E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N	ensemblbacteria:AAL81250(transcript)|ensemblbacteria:PF1126(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR013410(CRISPR-associated RAMP Cmr4)|rcsb pdb:4RDP|rcsb pdb:4W8W|rcsb pdb:4WNZ|refseq:WP_011012266.1|dip:DIP-54367N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497	rogid:Nm72GeycBUn1mj6QxSAdnMFsszA186497	rigid:aIu1ksl/3oa8tv75XagtFUniXOo	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S5	uniprotkb:Q8U1T0	intact:EBI-2504983|ensemblbacteria:AAL81254	intact:EBI-2504964|ensemblbacteria:AAL81249	psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name)	psi-mi:cmr5_pyrfu(display_long)|uniprotkb:cmr5(gene name)|psi-mi:cmr5(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr5(gene name synonym)|uniprotkb:PF1125(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036014|imex:IM-21002-2|dip:DIP-136390E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N	ensemblbacteria:AAL81249(transcript)|ensemblbacteria:PF1125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010160(CRISPR-associated protein, TM1791.1)|interpro:IPR023101|rcsb pdb:4GKF|refseq:WP_011012265.1|dip:DIP-54369N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497	rogid:vy8RHUFrrtBu6msl3Scl3awQtmM186497	rigid:aIu1ksl/3oa8tv75XagtFUniXOo	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S5	uniprotkb:Q8U1T1	intact:EBI-2504983|ensemblbacteria:AAL81254	intact:EBI-2504957|ensemblbacteria:AAL81248	psi-mi:cmr1a_pyrfu(display_long)|uniprotkb:cmr1-1(gene name)|psi-mi:cmr1-1(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr1-1(gene name synonym)|uniprotkb:PF1130(locus name)	psi-mi:cmr6_pyrfu(display_long)|uniprotkb:cmr6(gene name)|psi-mi:cmr6(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr6(gene name synonym)|uniprotkb:PF1124(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036014|imex:IM-21002-2|dip:DIP-136390E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81254(transcript)|ensemblbacteria:PF1130(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR007522(CRISPR-associated protein TM1795 family, N-terminal)|rcsb pdb:4W8X|rcsb pdb:4W8Z|refseq:WP_011012270.1|dip:DIP-54364N	ensemblbacteria:AAL81248(transcript)|ensemblbacteria:PF1124(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR010172(CRISPR-associated protein, TM1791)|rcsb pdb:4W8V|refseq:WP_011012264.1|dip:DIP-54368N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:SxmHMZkKYv1zvzBsZcLpo3pdqss186497	rogid:puSz7Udnj8h4VthO+EkLW7njqN0186497	rigid:aIu1ksl/3oa8tv75XagtFUniXOo	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S6	uniprotkb:Q8U1S7	intact:EBI-2504936|ensemblbacteria:AAL81253	intact:EBI-2504943|ensemblbacteria:AAL81252	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:cmr3_pyrfu(display_long)|uniprotkb:cmr3(gene name)|psi-mi:cmr3(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr3(gene name synonym)|uniprotkb:PF1128(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036100|imex:IM-21002-6|dip:DIP-190601E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	ensemblbacteria:PF1128(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010165(CRISPR-associated protein, TM1793)|interpro:IPR019117|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4H4K|ensemblbacteria:AAL81252(transcript)|refseq:WP_011012268.1|dip:DIP-54365N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rogid:vxqihIKFjSErsbCL6/OiH04DOlY186497	rigid:C8RzeNgn5l3k6W/mG2MsHxr1EdU	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S6	uniprotkb:Q8U1S9	intact:EBI-2504936|ensemblbacteria:AAL81253	intact:EBI-2504950|ensemblbacteria:AAL81250	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:cmr4_pyrfu(display_long)|uniprotkb:cmr4(gene name)|psi-mi:cmr4(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr4(gene name synonym)|uniprotkb:Target RNase Cmr4(gene name synonym)|uniprotkb:PF1126(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036100|imex:IM-21002-6|dip:DIP-190601E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	ensemblbacteria:AAL81250(transcript)|ensemblbacteria:PF1126(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR013410(CRISPR-associated RAMP Cmr4)|rcsb pdb:4RDP|rcsb pdb:4W8W|rcsb pdb:4WNZ|refseq:WP_011012266.1|dip:DIP-54367N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rogid:Nm72GeycBUn1mj6QxSAdnMFsszA186497	rigid:C8RzeNgn5l3k6W/mG2MsHxr1EdU	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S6	uniprotkb:Q8U1T0	intact:EBI-2504936|ensemblbacteria:AAL81253	intact:EBI-2504964|ensemblbacteria:AAL81249	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:cmr5_pyrfu(display_long)|uniprotkb:cmr5(gene name)|psi-mi:cmr5(display_short)|uniprotkb:CRISPR type III-B/RAMP module-associated protein Cmr5(gene name synonym)|uniprotkb:PF1125(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036100|imex:IM-21002-6|dip:DIP-190601E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	ensemblbacteria:AAL81249(transcript)|ensemblbacteria:PF1125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR010160(CRISPR-associated protein, TM1791.1)|interpro:IPR023101|rcsb pdb:4GKF|refseq:WP_011012265.1|dip:DIP-54369N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rogid:vy8RHUFrrtBu6msl3Scl3awQtmM186497	rigid:C8RzeNgn5l3k6W/mG2MsHxr1EdU	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:Q8U1S6	uniprotkb:Q8U1T1	intact:EBI-2504936|ensemblbacteria:AAL81253	intact:EBI-2504957|ensemblbacteria:AAL81248	psi-mi:cmr2_pyrfu(display_long)|uniprotkb:cmr2(gene name)|psi-mi:cmr2(display_short)|uniprotkb:CRISPR-associated protein Cas10/Cmr2, subtype III-B(gene name synonym)|uniprotkb:PF1129(locus name)	psi-mi:cmr6_pyrfu(display_long)|uniprotkb:cmr6(gene name)|psi-mi:cmr6(display_short)|uniprotkb:CRISPR type III-B/RAMP module RAMP protein Cmr6(gene name synonym)|uniprotkb:PF1124(locus name)	psi-mi:"MI:0071"(molecular sieving)	Shao et al. (2013)	pubmed:23395183|doi:"https://doi.org/10.1016/j.str.2013.01.002"|imex:IM-21002	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16036100|imex:IM-21002-6|dip:DIP-190601E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAL81253(transcript)|ensemblbacteria:PF1129(gene)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000160(GGDEF)|interpro:IPR013407(CRISPR-associated protein Crm2)|interpro:IPR024615|rcsb pdb:3UNG|rcsb pdb:3UR3|rcsb pdb:3W2V|rcsb pdb:3W2W|rcsb pdb:3X1L|rcsb pdb:4DOZ|rcsb pdb:4H4K|rcsb pdb:4W8Y|refseq:WP_011012269.1|dip:DIP-54366N	ensemblbacteria:AAL81248(transcript)|ensemblbacteria:PF1124(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0051607"(defense response to virus)|interpro:IPR005537(Protein of unknown function DUF324)|interpro:IPR010172(CRISPR-associated protein, TM1791)|rcsb pdb:4W8V|refseq:WP_011012264.1|dip:DIP-54368N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:d9FnTMz0cfhXoO0SYGctjK7Rphw186497	rogid:puSz7Udnj8h4VthO+EkLW7njqN0186497	rigid:C8RzeNgn5l3k6W/mG2MsHxr1EdU	false	-	-	-	-	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)