#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60830	uniprotkb:Q9Y3D7	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955506|imex:IM-25709-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161419.1|refseq:NP_005825.1|ensembl:ENSG00000126768(gene)|ensembl:ENST00000376582(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	-	-	-	figure legend:3A|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	rigid:c3vedFfzrRRBa/qtNBKYy6/vwys	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60830	uniprotkb:O14925	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766	intact:EBI-1047996|uniprotkb:Q53FF8|uniprotkb:Q6P5S5|uniprotkb:Q5T1E6|ensembl:ENSP00000464522	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	psi-mi:tim23_human(display_long)|uniprotkb:TIMM23(gene name)|psi-mi:TIMM23(display_short)|uniprotkb:TIM23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955506|imex:IM-25709-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161419.1|refseq:NP_005825.1|ensembl:ENSG00000126768(gene)|ensembl:ENST00000376582(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	refseq:NP_006318.1|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005681(Mitochondrial import inner membrane translocase, subunit Tim23)|mint:O14925|reactome:R-HSA-1268020|ensembl:ENSG00000265354(gene)|ensembl:ENST00000580018(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)	-	-	-	figure legend:3A|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	rogid:Hmu/kwfaPLGFGYBJH0oue7JDYqM9606	rigid:c3vedFfzrRRBa/qtNBKYy6/vwys	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60830	uniprotkb:Q3ZCQ8	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766	intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955506|imex:IM-25709-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161419.1|refseq:NP_005825.1|ensembl:ENSG00000126768(gene)|ensembl:ENST00000376582(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N	-	-	-	figure legend:3A|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606	rigid:c3vedFfzrRRBa/qtNBKYy6/vwys	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60830	uniprotkb:Q9Y5T4	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955506|imex:IM-25709-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161419.1|refseq:NP_005825.1|ensembl:ENSG00000126768(gene)|ensembl:ENST00000376582(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	-	-	-	figure legend:3A|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rigid:c3vedFfzrRRBa/qtNBKYy6/vwys	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y5T4	uniprotkb:Q9Y3D7	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955515|imex:IM-25709-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	-	-	-	figure legend:3B-1|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	rigid:PkE5/xaigupIFsknhVjRaUwSkq4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y5T4	uniprotkb:Q99595	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	intact:EBI-727290|uniprotkb:Q9BWF5|uniprotkb:B2RDM5|ensembl:ENSP00000356256	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:ti17a_human(display_long)|uniprotkb:Inner membrane preprotein translocase Tim17a(gene name synonym)|uniprotkb:TIMM17A(gene name)|psi-mi:TIMM17A(display_short)|uniprotkb:MIMT17(gene name synonym)|uniprotkb:TIM17(gene name synonym)|uniprotkb:TIM17A(gene name synonym)|uniprotkb:TIMM17(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955515|imex:IM-25709-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	refseq:NP_006326.1|ensembl:ENSG00000134375(gene)|ensembl:ENST00000367287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	-	-	-	figure legend:3B-1|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rogid:fHf+KQjrFx8eyY+3EH8nVmBq8KE9606	rigid:PkE5/xaigupIFsknhVjRaUwSkq4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y5T4	uniprotkb:O60830	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955515|imex:IM-25709-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	refseq:NP_001161419.1|refseq:NP_005825.1|ensembl:ENSG00000126768(gene)|ensembl:ENST00000376582(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	-	-	-	figure legend:3B-1|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	rigid:PkE5/xaigupIFsknhVjRaUwSkq4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y5T4	uniprotkb:O60830	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	intact:EBI-2372529|uniprotkb:Q9UJV0|uniprotkb:A8K2E2|uniprotkb:J3KPV3|ensembl:ENSP00000365766	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:ti17b_human(display_long)|uniprotkb:TIMM17B(gene name)|psi-mi:TIMM17B(display_short)|uniprotkb:TIM17B(gene name synonym)|uniprotkb:JM3(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955523|imex:IM-25709-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	refseq:NP_001161419.1|refseq:NP_005825.1|ensembl:ENSG00000126768(gene)|ensembl:ENST00000376582(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005678(Mitochondrial import inner membrane translocase, subunit Tim17)|reactome:R-HSA-1268020	-	-	-	figure legend:3B-2|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rogid:2jmF1ZItisqPDfdGgX/bY9FFE9E9606	rigid:WoRlWznmVSh/mCTaxVrCYSQ71XY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y5T4	uniprotkb:Q9Y3D7	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955523|imex:IM-25709-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	-	-	-	figure legend:3B-2|comment:cells were lysed with digitonin|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	rigid:WoRlWznmVSh/mCTaxVrCYSQ71XY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y3D7	uniprotkb:Q9Y5T4	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955537|imex:IM-25709-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	-	-	-	figure legend:3C|comment:cells were lysed with Triton-X-100|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/22	2017/03/30	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rigid:J8Q7J8rjII7KmoSprVNIAhBrzZo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y5T4	uniprotkb:Q9Y3D7	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:"MI:0096"(pull down)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955554|imex:IM-25709-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	-	-	-	figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2017/02/22	2017/04/11	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	rigid:J8Q7J8rjII7KmoSprVNIAhBrzZo	false	sufficient binding region:57-150	his tag:n-n|sufficient binding region:24-125	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
chebi:"CHEBI:15422"	uniprotkb:P38646	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955574|imex:IM-25709-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:5-1|kinetics:Enzyme activity = 0.033 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	-	false	-	his tag:n-n|sufficient binding region:51-679	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9HAV7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13955574|imex:IM-25709-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	-	-	-	figure legend:5-1|kinetics:Enzyme activity = 0.033 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	-	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P38646	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001259|imex:IM-25709-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:5-2|kinetics:Enzyme activity is ~ 0.09 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	-	false	-	his tag:n-n|sufficient binding region:51-679	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9HAV7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001259|imex:IM-25709-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	-	-	-	figure legend:5-2|kinetics:Enzyme activity is ~ 0.09 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	-	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q96DA6	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-9679081|uniprotkb:B2R4B1|uniprotkb:C9JBV1|ensembl:ENSP00000372005	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:tim14_human(display_long)|uniprotkb:DNAJC19(gene name)|psi-mi:DNAJC19(display_short)|uniprotkb:TIM14(gene name synonym)|uniprotkb:TIMM14(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 19(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001259|imex:IM-25709-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001177162.1|refseq:NP_660304.1|dip:DIP-62091N|ensembl:ENSG00000205981(gene)|ensembl:ENST00000382564(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048806"(genitalia development)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|reactome:R-HSA-1268020	-	-	-	figure legend:5-2|kinetics:Enzyme activity is ~ 0.09 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:D4F4Zp25GxZQckdl1pJaBwciYik9606	-	false	-	sufficient binding region:24-116|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9Y5T4	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001276|imex:IM-25709-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	-	-	-	figure legend:5-3|kinetics:Enzyme activity is ~ 0.1 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	-	false	-	sufficient binding region:57-150|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P38646	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001276|imex:IM-25709-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:5-3|kinetics:Enzyme activity is ~ 0.1 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	-	false	-	his tag:n-n|sufficient binding region:51-679	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9HAV7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001276|imex:IM-25709-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	-	-	-	figure legend:5-3|kinetics:Enzyme activity is ~ 0.1 mol ATP/ mol mortalin/ minute.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	-	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9Y5T4	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001296|imex:IM-25709-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	-	-	-	figure legend:5-4|kinetics:Enzyme activity is ~ 0.04 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	-	false	-	sufficient binding region:57-150|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P38646	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001296|imex:IM-25709-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:5-4|kinetics:Enzyme activity is ~ 0.04 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	-	false	-	his tag:n-n|sufficient binding region:51-679	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9HAV7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001296|imex:IM-25709-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	-	-	-	figure legend:5-4|kinetics:Enzyme activity is ~ 0.04 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	-	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9Y3D7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001296|imex:IM-25709-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	-	-	-	figure legend:5-4|kinetics:Enzyme activity is ~ 0.04 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	-	false	-	sufficient binding region:24-125|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9Y5T4	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-10329228|uniprotkb:Q5T219|uniprotkb:Q6X963|uniprotkb:B2R4L0|ensembl:ENSP00000368523	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:djc15_human(display_long)|uniprotkb:DNAJC15(gene name)|psi-mi:DNAJC15(display_short)|uniprotkb:Cell growth-inhibiting gene 22 protein(gene name synonym)|uniprotkb:DNAJD1(gene name synonym)|uniprotkb:Methylation-controlled J protein(gene name synonym)|uniprotkb:GIG22(orf name)|uniprotkb:HSD18(orf name)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001320|imex:IM-25709-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_037370.2|ensembl:ENSG00000120675(gene)|ensembl:ENST00000379221(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:1902957"(negative regulation of mitochondrial electron transport, NADH to ubiquinone)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869	-	-	-	figure legend:5-5|kinetics:Enzyme activity is ~ 0.05 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|comment:"pre-incubation of his-tagged MAGMAS(s) with MCJ(s)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:LdyQEV/gBm++VC/YXOyyCw041d49606	-	false	-	sufficient binding region:57-150	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:P38646	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001320|imex:IM-25709-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:5-5|kinetics:Enzyme activity is ~ 0.05 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|comment:"pre-incubation of his-tagged MAGMAS(s) with MCJ(s)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	-	false	-	his tag:n-n|sufficient binding region:51-679	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9HAV7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001320|imex:IM-25709-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	-	-	-	figure legend:5-5|kinetics:Enzyme activity is ~ 0.05 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|comment:"pre-incubation of his-tagged MAGMAS(s) with MCJ(s)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	-	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15422"	uniprotkb:Q9Y3D7	intact:EBI-1108845|chebi:"CHEBI:40938"|chebi:"CHEBI:10841"|chebi:"CHEBI:10789"|chebi:"CHEBI:2359"|chebi:"CHEBI:13236"|chebi:"CHEBI:22249"	intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678	psi-mi:atp(display_short)|psi-mi:"CHEBI:15422"(display_long)|intact:Adenosine 5'-triphosphate(synonym)|intact:Adenosine triphosphate(synonym)|intact:ADENOSINE-5'-TRIPHOSPHATE(synonym)|intact:Adephos(synonym)|intact:Adetol(synonym)|intact:Adynol(synonym)|intact:Atipi(synonym)|intact:ATP(synonym)|intact:Atriphos(synonym)|intact:Cardenosine(synonym)|intact:Fosfobion(synonym)|intact:Glucobasin(synonym)|intact:H4atp(synonym)|intact:Myotriphos(synonym)|intact:Triadenyl(synonym)|intact:Triphosphaden(synonym)|intact:"adenosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym)	psi-mi:"MI:0880"(atpase assay)	Schusdziarra et al. (2013)	pubmed:23263864|imex:IM-25709	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0882"(atpase reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-14001320|imex:IM-25709-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene)	-	-	-	figure legend:5-5|kinetics:Enzyme activity is ~ 0.05 mol ATP/ mol mortalin/ minute.|comment:"The basal ATPase activity of mortalin was not decreased in the presence of MAGMAS(s) when added alone, in the absence of MCJ."|comment:"pre-incubation of his-tagged MAGMAS(s) with MCJ(s)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/22	2017/04/03	-	rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606	-	false	-	sufficient binding region:24-125|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)