#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63073	uniprotkb:Q6NZJ6	intact:EBI-2000006|uniprotkb:P20415|ensembl:ENSMUSP00000029803	intact:EBI-8175606|uniprotkb:Q6NZN8|uniprotkb:Q8BW99|intact:MINT-1856450|ensembl:ENSMUSP00000047678|ensembl:ENSMUSP00000111120	psi-mi:if4e_mouse(display_long)|uniprotkb:Eif4e(gene name)|psi-mi:Eif4e(display_short)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)	psi-mi:if4g1_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Santini et al. (2013)	pubmed:23263185|doi:10.1038/nature11782|imex:IM-20773	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16029682|imex:IM-20773-1|dip:DIP-190473E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031943.3|dip:DIP-42768N|ensembl:ENSMUSG00000028156(gene)|ensembl:ENSMUST00000029803(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:1EJ1|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1L8B|rcsb pdb:5BXV|rcsb pdb:5J5O|rcsb pdb:5J5Y|rcsb pdb:5M7V|rcsb pdb:5M7W|rcsb pdb:5M7X|rcsb pdb:5M7Z|rcsb pdb:5M80|rcsb pdb:5M81|rcsb pdb:5M83|rcsb pdb:5M84|rcsb pdb:5OSX|rcsb pdb:6GKJ|rcsb pdb:6GKK|rcsb pdb:6GKL|rcsb pdb:6U06|rcsb pdb:6U09|rcsb pdb:6YLR|rcsb pdb:6YLT|rcsb pdb:6YLV|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706	refseq:NP_001291361.1|refseq:NP_666053.2|refseq:XP_006522000.1|dip:DIP-42771N|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|reactome:R-MMU-975957|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q6NZJ6|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000044783(transcript)|ensembl:ENSMUST00000115460(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)	psi-mi:"MI:0465"(dip)	-	comment:mint|function:Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:DnMmfgiMq6RHbSuRPwy/TaoeySU10090	rogid:91tJB28zzWTM77Jg0kZ18KIUhmo10090	rigid:8EsQaMBixE/iLVrMewJvrhVuZNc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P63073	uniprotkb:P70445	intact:EBI-2000006|uniprotkb:P20415|ensembl:ENSMUSP00000029803	intact:EBI-16029654|ensembl:ENSMUSP00000020288|ensembl:ENSMUSP00000131952	psi-mi:if4e_mouse(display_long)|uniprotkb:Eif4e(gene name)|psi-mi:Eif4e(display_short)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)	psi-mi:4ebp2_mouse(display_long)|uniprotkb:Eif4ebp2(gene name)|psi-mi:Eif4ebp2(display_short)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Santini et al. (2013)	pubmed:23263185|doi:10.1038/nature11782|imex:IM-20773	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16029682|imex:IM-20773-1|dip:DIP-190473E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031943.3|dip:DIP-42768N|ensembl:ENSMUSG00000028156(gene)|ensembl:ENSMUST00000029803(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:1EJ1|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1L8B|rcsb pdb:5BXV|rcsb pdb:5J5O|rcsb pdb:5J5Y|rcsb pdb:5M7V|rcsb pdb:5M7W|rcsb pdb:5M7X|rcsb pdb:5M7Z|rcsb pdb:5M80|rcsb pdb:5M81|rcsb pdb:5M83|rcsb pdb:5M84|rcsb pdb:5OSX|rcsb pdb:6GKJ|rcsb pdb:6GKK|rcsb pdb:6GKL|rcsb pdb:6U06|rcsb pdb:6U09|rcsb pdb:6YLR|rcsb pdb:6YLT|rcsb pdb:6YLV|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706	ensembl:ENSMUSG00000020091(gene)|ensembl:ENSMUST00000020288(transcript)|ensembl:ENSMUST00000167087(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007613"(memory)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0035176"(social behavior)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|refseq:NP_034254.1|refseq:XP_017169281.1|refseq:XP_017169282.1|dip:DIP-60124N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:DnMmfgiMq6RHbSuRPwy/TaoeySU10090	rogid:6W2cMw7+lGVpDdKKIwiS4c/SwXc10090	rigid:8EsQaMBixE/iLVrMewJvrhVuZNc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6NZJ6	uniprotkb:P63073	intact:EBI-8175606|uniprotkb:Q6NZN8|uniprotkb:Q8BW99|intact:MINT-1856450|ensembl:ENSMUSP00000047678|ensembl:ENSMUSP00000111120	intact:EBI-2000006|uniprotkb:P20415|ensembl:ENSMUSP00000029803	psi-mi:if4g1_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short)	psi-mi:if4e_mouse(display_long)|uniprotkb:Eif4e(gene name)|psi-mi:Eif4e(display_short)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Santini et al. (2013)	pubmed:23263185|doi:10.1038/nature11782|imex:IM-20773	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16029700|imex:IM-20773-2|dip:DIP-72709E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291361.1|refseq:NP_666053.2|refseq:XP_006522000.1|dip:DIP-42771N|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|reactome:R-MMU-975957|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q6NZJ6|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000044783(transcript)|ensembl:ENSMUST00000115460(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)	refseq:NP_031943.3|dip:DIP-42768N|ensembl:ENSMUSG00000028156(gene)|ensembl:ENSMUST00000029803(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:1EJ1|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1L8B|rcsb pdb:5BXV|rcsb pdb:5J5O|rcsb pdb:5J5Y|rcsb pdb:5M7V|rcsb pdb:5M7W|rcsb pdb:5M7X|rcsb pdb:5M7Z|rcsb pdb:5M80|rcsb pdb:5M81|rcsb pdb:5M83|rcsb pdb:5M84|rcsb pdb:5OSX|rcsb pdb:6GKJ|rcsb pdb:6GKK|rcsb pdb:6GKL|rcsb pdb:6U06|rcsb pdb:6U09|rcsb pdb:6YLR|rcsb pdb:6YLT|rcsb pdb:6YLV|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706	psi-mi:"MI:0465"(dip)	comment:mint|function:Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:91tJB28zzWTM77Jg0kZ18KIUhmo10090	rogid:DnMmfgiMq6RHbSuRPwy/TaoeySU10090	rigid:zhMdIe5eULBjkVeouFl9sOFfjbQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6NZJ6	uniprotkb:P63073	intact:EBI-8175606|uniprotkb:Q6NZN8|uniprotkb:Q8BW99|intact:MINT-1856450|ensembl:ENSMUSP00000047678|ensembl:ENSMUSP00000111120	intact:EBI-2000006|uniprotkb:P20415|ensembl:ENSMUSP00000029803	psi-mi:if4g1_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short)	psi-mi:if4e_mouse(display_long)|uniprotkb:Eif4e(gene name)|psi-mi:Eif4e(display_short)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Santini et al. (2013)	pubmed:23263185|doi:10.1038/nature11782|imex:IM-20773	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16029717|imex:IM-20773-3|dip:DIP-72709E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291361.1|refseq:NP_666053.2|refseq:XP_006522000.1|dip:DIP-42771N|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|reactome:R-MMU-975957|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q6NZJ6|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000044783(transcript)|ensembl:ENSMUST00000115460(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)	refseq:NP_031943.3|dip:DIP-42768N|ensembl:ENSMUSG00000028156(gene)|ensembl:ENSMUST00000029803(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:1EJ1|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1L8B|rcsb pdb:5BXV|rcsb pdb:5J5O|rcsb pdb:5J5Y|rcsb pdb:5M7V|rcsb pdb:5M7W|rcsb pdb:5M7X|rcsb pdb:5M7Z|rcsb pdb:5M80|rcsb pdb:5M81|rcsb pdb:5M83|rcsb pdb:5M84|rcsb pdb:5OSX|rcsb pdb:6GKJ|rcsb pdb:6GKK|rcsb pdb:6GKL|rcsb pdb:6U06|rcsb pdb:6U09|rcsb pdb:6YLR|rcsb pdb:6YLT|rcsb pdb:6YLV|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706	psi-mi:"MI:0465"(dip)	comment:mint|function:Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/07	2017/08/10	rogid:91tJB28zzWTM77Jg0kZ18KIUhmo10090	rogid:DnMmfgiMq6RHbSuRPwy/TaoeySU10090	rigid:zhMdIe5eULBjkVeouFl9sOFfjbQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)