#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P51681	uniprotkb:O54081	intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881	intact:EBI-16027720	psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym)	psi-mi:luke_staau(display_long)|uniprotkb:lukE(gene name)|psi-mi:lukE(display_short)	psi-mi:"MI:0096"(pull down)	Alonzo et al. (2013)	pubmed:23235831|doi:10.1038/nature11724|imex:IM-20767	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16027731|imex:IM-20767-1|dip:DIP-190468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N	go:"GO:0005576"(extracellular region)|go:"GO:0051715"(cytolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|dip:DIP-60119N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606	rogid:l/pPEQlJX0UlqHcBoCfzpDXj5kU1280	rigid:BJ8o4z38nkgUnlaTvXpo5m+5i4s	false	ha tag:n-n	his tag:n-n|sufficient binding region:29-314	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51681	uniprotkb:O54081	intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881	intact:EBI-16027720	psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym)	psi-mi:luke_staau(display_long)|uniprotkb:lukE(gene name)|psi-mi:lukE(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Alonzo et al. (2013)	pubmed:23235831|doi:10.1038/nature11724|imex:IM-20767	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1280(staau)|taxid:1280(Staphylococcus aureus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16027754|imex:IM-20767-2|dip:DIP-190468E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N	go:"GO:0005576"(extracellular region)|go:"GO:0051715"(cytolysis in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR003963(Bi-component toxin, staphylococci)|interpro:IPR016183(Leukocidin/porin)|interpro:IPR036435|dip:DIP-60119N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606	rogid:l/pPEQlJX0UlqHcBoCfzpDXj5kU1280	rigid:BJ8o4z38nkgUnlaTvXpo5m+5i4s	false	-	sufficient binding region:29-314	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)