#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9W3D3 uniprotkb:O18335 intact:EBI-868608|uniprotkb:O96957|uniprotkb:Q8T3K8|uniprotkb:Q9W3D2|ensemblmetazoa:FBpp0071165|ensemblmetazoa:FBpp0089320|ensemblmetazoa:FBpp0310013 intact:EBI-148897|ensemblmetazoa:FBpp0083413|ensemblmetazoa:FBpp0083414 psi-mi:crag_drome(display_long)|uniprotkb:Crag(gene name)|psi-mi:Crag(display_short)|uniprotkb:CG12737(orf name)|uniprotkb:Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein(gene name synonym) psi-mi:o18335_drome(display_long)|uniprotkb:Rab11(gene name)|psi-mi:Rab11(display_short)|uniprotkb:Drab11(gene name synonym)|uniprotkb:CG5771(orf name)|uniprotkb:AAF55850(gene name synonym)|uniprotkb:DRAB11(gene name synonym)|uniprotkb:DRab11(gene name synonym)|uniprotkb:Dm Rab11(gene name synonym)|uniprotkb:DmRab11(gene name synonym)|uniprotkb:Dmel\CG5771(gene name synonym)|uniprotkb:O18335(gene name synonym)|uniprotkb:RAB11(gene name synonym)|uniprotkb:Rab 11(gene name synonym)|uniprotkb:Rab-11(gene name synonym)|uniprotkb:Rab-r11(gene name synonym)|uniprotkb:dRab11(gene name synonym)|uniprotkb:"l(3)93Bi"(gene name synonym)|uniprotkb:"l(3)j2D1"(gene name synonym)|uniprotkb:rab-11(gene name synonym)|uniprotkb:rab11(gene name synonym)|uniprotkb:rlr7(gene name synonym)|uniprotkb:Dmel_CG5771(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xiong et al. (2011) pubmed:23226104|doi:10.1371/journal.pbio.1001438|imex:IM-20606 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16027614|imex:IM-20606-1|dip:DIP-190164E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025864|dip:DIP-59994N|refseq:NP_727281.2|refseq:NP_001162710.2|refseq:NP_525080.3|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBtr0071219(transcript)|ensemblmetazoa:FBtr0071220(transcript)|ensemblmetazoa:FBtr0343356(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055037"(recycling endosome)|go:"GO:0061864"(basement membrane constituent secretion)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0110010"(basolateral protein secretion)|go:"GO:0110011"(regulation of basement membrane organization)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|reactome:R-DME-8876198|ensemblmetazoa:FBgn0025864(gene) refseq:NP_477170.1|refseq:NP_599137.1|flybase:FBgn0015790|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030707"(ovarian follicle cell development)|ensemblmetazoa:FBgn0015790(gene)|ensemblmetazoa:FBtr0084010(transcript)|ensemblmetazoa:FBtr0084011(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003924"(GTPase activity)|dip:DIP-47764N|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045169"(fusome)|go:"GO:0045202"(synapse)|go:"GO:0045478"(fusome organization)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048599"(oocyte development)|go:"GO:0048749"(compound eye development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051642"(centrosome localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|go:"GO:0072657"(protein localization to membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:O18335|reactome:R-DME-432040|reactome:R-DME-5620916|reactome:R-DME-8873719 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/07 2018/09/18 rogid:ut74u3wVPw2fsMS/h3YLzo9MVf47227 rogid:rlrB7RSZlXyRgSO5ZjjN0nyRhe07227 rigid:4rvN1nISPdmo60UxW4KJBrqUBb8 false sufficient binding region:299-734|flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15971 uniprotkb:Q9W3D3 intact:EBI-16027637|ensemblmetazoa:FBpp0077029 intact:EBI-868608|uniprotkb:O96957|uniprotkb:Q8T3K8|uniprotkb:Q9W3D2|ensemblmetazoa:FBpp0071165|ensemblmetazoa:FBpp0089320|ensemblmetazoa:FBpp0310013 psi-mi:o15971_drome(display_long)|uniprotkb:AAF50924(gene name synonym)|uniprotkb:DRAB10(gene name synonym)|uniprotkb:DmRab10(gene name synonym)|uniprotkb:Dmel\CG17060(gene name synonym)|uniprotkb:O15971(gene name synonym)|uniprotkb:Rab-r10(gene name synonym)|uniprotkb:rab10(gene name synonym)|uniprotkb:Dmel_CG17060(orf name)|uniprotkb:CG17060(orf name)|uniprotkb:Rab10(gene name)|psi-mi:Rab10(display_short)|uniprotkb:DRab10(gene name synonym) psi-mi:crag_drome(display_long)|uniprotkb:Crag(gene name)|psi-mi:Crag(display_short)|uniprotkb:CG12737(orf name)|uniprotkb:Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein(gene name synonym) psi-mi:"MI:0949"(gdp/gtp exchange assay) Xiong et al. (2011) pubmed:23226104|doi:10.1371/journal.pbio.1001438|imex:IM-20606 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16027673|imex:IM-20606-2|dip:DIP-190165E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015789(gene)|ensemblmetazoa:FBtr0077337(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007295"(growth of a germarium-derived egg chamber)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045175"(basal protein localization)|go:"GO:0045178"(basal part of cell)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0055037"(recycling endosome)|go:"GO:0061864"(basement membrane constituent secretion)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0110010"(basolateral protein secretion)|go:"GO:0110011"(regulation of basement membrane organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DME-6798695|reactome:R-DME-8873719|reactome:R-DME-8876198|refseq:NP_523419.1|flybase:FBgn0015789|dip:DIP-59995N flybase:FBgn0025864|dip:DIP-59994N|refseq:NP_727281.2|refseq:NP_001162710.2|refseq:NP_525080.3|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBtr0071219(transcript)|ensemblmetazoa:FBtr0071220(transcript)|ensemblmetazoa:FBtr0343356(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055037"(recycling endosome)|go:"GO:0061864"(basement membrane constituent secretion)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0110010"(basolateral protein secretion)|go:"GO:0110011"(regulation of basement membrane organization)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|reactome:R-DME-8876198|ensemblmetazoa:FBgn0025864(gene) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2018/09/18 rogid:87ex8/H9Orfx+AMGaCY899T6BpA7227 rogid:ut74u3wVPw2fsMS/h3YLzo9MVf47227 rigid:n/oZ0ZkrWoituW6ST678OrG+Sto false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9W3D3 uniprotkb:O18335 intact:EBI-868608|uniprotkb:O96957|uniprotkb:Q8T3K8|uniprotkb:Q9W3D2|ensemblmetazoa:FBpp0071165|ensemblmetazoa:FBpp0089320|ensemblmetazoa:FBpp0310013 intact:EBI-148897|ensemblmetazoa:FBpp0083413|ensemblmetazoa:FBpp0083414 psi-mi:crag_drome(display_long)|uniprotkb:Crag(gene name)|psi-mi:Crag(display_short)|uniprotkb:CG12737(orf name)|uniprotkb:Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein(gene name synonym) psi-mi:o18335_drome(display_long)|uniprotkb:Rab11(gene name)|psi-mi:Rab11(display_short)|uniprotkb:Drab11(gene name synonym)|uniprotkb:CG5771(orf name)|uniprotkb:AAF55850(gene name synonym)|uniprotkb:DRAB11(gene name synonym)|uniprotkb:DRab11(gene name synonym)|uniprotkb:Dm Rab11(gene name synonym)|uniprotkb:DmRab11(gene name synonym)|uniprotkb:Dmel\CG5771(gene name synonym)|uniprotkb:O18335(gene name synonym)|uniprotkb:RAB11(gene name synonym)|uniprotkb:Rab 11(gene name synonym)|uniprotkb:Rab-11(gene name synonym)|uniprotkb:Rab-r11(gene name synonym)|uniprotkb:dRab11(gene name synonym)|uniprotkb:"l(3)93Bi"(gene name synonym)|uniprotkb:"l(3)j2D1"(gene name synonym)|uniprotkb:rab-11(gene name synonym)|uniprotkb:rab11(gene name synonym)|uniprotkb:rlr7(gene name synonym)|uniprotkb:Dmel_CG5771(orf name) psi-mi:"MI:0949"(gdp/gtp exchange assay) Xiong et al. (2011) pubmed:23226104|doi:10.1371/journal.pbio.1001438|imex:IM-20606 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16027690|imex:IM-20606-3|dip:DIP-190164E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0025864|dip:DIP-59994N|refseq:NP_727281.2|refseq:NP_001162710.2|refseq:NP_525080.3|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBgn0025864(gene)|ensemblmetazoa:FBtr0071219(transcript)|ensemblmetazoa:FBtr0071220(transcript)|ensemblmetazoa:FBtr0343356(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045175"(basal protein localization)|go:"GO:0045179"(apical cortex)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055037"(recycling endosome)|go:"GO:0061864"(basement membrane constituent secretion)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0110010"(basolateral protein secretion)|go:"GO:0110011"(regulation of basement membrane organization)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|reactome:R-DME-8876198|ensemblmetazoa:FBgn0025864(gene) refseq:NP_477170.1|refseq:NP_599137.1|flybase:FBgn0015790|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0030723"(ovarian fusome organization)|go:"GO:0005525"(GTP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007317"(regulation of pole plasm oskar mRNA localization)|go:"GO:0007349"(cellularization)|go:"GO:0007391"(dorsal closure)|go:"GO:0007394"(dorsal closure, elongation of leading edge cells)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0022416"(chaeta development)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030707"(ovarian follicle cell development)|ensemblmetazoa:FBgn0015790(gene)|ensemblmetazoa:FBtr0084010(transcript)|ensemblmetazoa:FBtr0084011(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0003924"(GTPase activity)|dip:DIP-47764N|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045169"(fusome)|go:"GO:0045202"(synapse)|go:"GO:0045478"(fusome organization)|go:"GO:0046664"(dorsal closure, amnioserosa morphology change)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048137"(spermatocyte division)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048599"(oocyte development)|go:"GO:0048749"(compound eye development)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051642"(centrosome localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0060187"(cell pole)|go:"GO:0070732"(spindle envelope)|go:"GO:0072657"(protein localization to membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:O18335|reactome:R-DME-432040|reactome:R-DME-5620916|reactome:R-DME-8873719 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2018/09/18 rogid:ut74u3wVPw2fsMS/h3YLzo9MVf47227 rogid:rlrB7RSZlXyRgSO5ZjjN0nyRhe07227 rigid:4rvN1nISPdmo60UxW4KJBrqUBb8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)