#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7TMF2 uniprotkb:Q8VC85 intact:EBI-16026214|uniprotkb:Q3TA98|uniprotkb:Q3TNT0|uniprotkb:Q80UN4|uniprotkb:Q8BWR6|uniprotkb:Q9CQ63 intact:EBI-16026183|ensembl:ENSMUSP00000041022 psi-mi:eri1_mouse(display_long)|uniprotkb:Eri1(gene name)|psi-mi:Eri1(display_short)|uniprotkb:3'exo(gene name synonym)|uniprotkb:Thex1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym) psi-mi:lsm1_mouse(display_long)|uniprotkb:Lsm1(gene name)|psi-mi:Lsm1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hoefig et al. (2013) pubmed:23202588|doi:10.1038/nsmb.2450|imex:IM-20758 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16026247|imex:IM-20758-1|dip:DIP-190436E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|reactome:R-MMU-6791226|dip:DIP-60112N|refseq:NP_080343.4 ensembl:ENSMUSG00000037296(gene)|ensembl:ENSMUST00000038421(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-MMU-430039|dip:DIP-60113N|refseq:NP_080308.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:7a1LEh8uXxhti4YylOhiX6dkO3I10090 rogid:aWdeQ47hMdnvLy9DKXHb7PBkI0s10090 rigid:vNmrfuaQgke2ra7uLkc7gw2yG/I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9EPU0 uniprotkb:Q7TMF2 intact:EBI-6876715|ensembl:ENSMUSP00000075089|uniprotkb:Q3UG00|uniprotkb:Q6GYP5|uniprotkb:Q6PHQ5|uniprotkb:Q8K0N4|uniprotkb:Q99PR4 intact:EBI-16026214|uniprotkb:Q3TA98|uniprotkb:Q3TNT0|uniprotkb:Q80UN4|uniprotkb:Q8BWR6|uniprotkb:Q9CQ63 psi-mi:rent1_mouse(display_long)|uniprotkb:Upf1(gene name)|psi-mi:Upf1(display_short)|uniprotkb:Rent1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:eri1_mouse(display_long)|uniprotkb:Eri1(gene name)|psi-mi:Eri1(display_short)|uniprotkb:3'exo(gene name synonym)|uniprotkb:Thex1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hoefig et al. (2013) pubmed:23202588|doi:10.1038/nsmb.2450|imex:IM-20758 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16026264|imex:IM-20758-2|dip:DIP-190438E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000058301(gene)|ensembl:ENSMUST00000075666(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q9EPU0|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0042162"(telomeric DNA binding)|refseq:XP_006509667.1|refseq:XP_006509668.1|refseq:NP_001116301.1|refseq:NP_109605.2|dip:DIP-60114N go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|reactome:R-MMU-6791226|dip:DIP-60112N|refseq:NP_080343.4 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:rwd4XXdf5Uqjtgao/zILckKP8AM10090 rogid:7a1LEh8uXxhti4YylOhiX6dkO3I10090 rigid:9a9ebS9RChrvjEaMaU8GXrQ/0Vo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7TMF2 uniprotkb:Q8VC85 intact:EBI-16026214|uniprotkb:Q3TA98|uniprotkb:Q3TNT0|uniprotkb:Q80UN4|uniprotkb:Q8BWR6|uniprotkb:Q9CQ63 intact:EBI-16026183|ensembl:ENSMUSP00000041022 psi-mi:eri1_mouse(display_long)|uniprotkb:Eri1(gene name)|psi-mi:Eri1(display_short)|uniprotkb:3'exo(gene name synonym)|uniprotkb:Thex1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym) psi-mi:lsm1_mouse(display_long)|uniprotkb:Lsm1(gene name)|psi-mi:Lsm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hoefig et al. (2013) pubmed:23202588|doi:10.1038/nsmb.2450|imex:IM-20758 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16026281|imex:IM-20758-3|dip:DIP-190436E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|reactome:R-MMU-6791226|dip:DIP-60112N|refseq:NP_080343.4 ensembl:ENSMUSG00000037296(gene)|ensembl:ENSMUST00000038421(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-MMU-430039|dip:DIP-60113N|refseq:NP_080308.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:7a1LEh8uXxhti4YylOhiX6dkO3I10090 rogid:aWdeQ47hMdnvLy9DKXHb7PBkI0s10090 rigid:vNmrfuaQgke2ra7uLkc7gw2yG/I false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9QXA5 uniprotkb:Q7TMF2 intact:EBI-16026300 intact:EBI-16026214|uniprotkb:Q3TA98|uniprotkb:Q3TNT0|uniprotkb:Q80UN4|uniprotkb:Q8BWR6|uniprotkb:Q9CQ63 psi-mi:lsm4_mouse(display_long)|uniprotkb:Lsm4(gene name)|psi-mi:Lsm4(display_short) psi-mi:eri1_mouse(display_long)|uniprotkb:Eri1(gene name)|psi-mi:Eri1(display_short)|uniprotkb:3'exo(gene name synonym)|uniprotkb:Thex1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hoefig et al. (2013) pubmed:23202588|doi:10.1038/nsmb.2450|imex:IM-20758 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16026327|imex:IM-20758-4|dip:DIP-190439E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0043005"(neuron projection)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|reactome:R-MMU-430039|reactome:R-MMU-72163|dip:DIP-60115N|refseq:NP_056631.2 go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|reactome:R-MMU-6791226|dip:DIP-60112N|refseq:NP_080343.4 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:VdarfNUoXCy1z3rssjckjNfsZjs10090 rogid:7a1LEh8uXxhti4YylOhiX6dkO3I10090 rigid:WZ9lULBWRjBW6GVDF/NtoyYed/g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7TMF2 uniprotkb:Q9EPU0 intact:EBI-16026214|uniprotkb:Q3TA98|uniprotkb:Q3TNT0|uniprotkb:Q80UN4|uniprotkb:Q8BWR6|uniprotkb:Q9CQ63 intact:EBI-6876715|ensembl:ENSMUSP00000075089|uniprotkb:Q3UG00|uniprotkb:Q6GYP5|uniprotkb:Q6PHQ5|uniprotkb:Q8K0N4|uniprotkb:Q99PR4 psi-mi:eri1_mouse(display_long)|uniprotkb:Eri1(gene name)|psi-mi:Eri1(display_short)|uniprotkb:3'exo(gene name synonym)|uniprotkb:Thex1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym) psi-mi:rent1_mouse(display_long)|uniprotkb:Upf1(gene name)|psi-mi:Upf1(display_short)|uniprotkb:Rent1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hoefig et al. (2013) pubmed:23202588|doi:10.1038/nsmb.2450|imex:IM-20758 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16026344|imex:IM-20758-5|dip:DIP-190437E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|reactome:R-MMU-6791226|dip:DIP-60112N|refseq:NP_080343.4 ensembl:ENSMUSG00000058301(gene)|ensembl:ENSMUST00000075666(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q9EPU0|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0042162"(telomeric DNA binding)|refseq:XP_006509667.1|refseq:XP_006509668.1|refseq:NP_001116301.1|refseq:NP_109605.2|dip:DIP-60114N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:7a1LEh8uXxhti4YylOhiX6dkO3I10090 rogid:rwd4XXdf5Uqjtgao/zILckKP8AM10090 rigid:KBApjUBNL0nBzR21ZpY6e7CSEpY false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7TMF2 uniprotkb:Q8VC85 intact:EBI-16026214|uniprotkb:Q3TA98|uniprotkb:Q3TNT0|uniprotkb:Q80UN4|uniprotkb:Q8BWR6|uniprotkb:Q9CQ63 intact:EBI-16026183|ensembl:ENSMUSP00000041022 psi-mi:eri1_mouse(display_long)|uniprotkb:Eri1(gene name)|psi-mi:Eri1(display_short)|uniprotkb:3'exo(gene name synonym)|uniprotkb:Thex1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym) psi-mi:lsm1_mouse(display_long)|uniprotkb:Lsm1(gene name)|psi-mi:Lsm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hoefig et al. (2013) pubmed:23202588|doi:10.1038/nsmb.2450|imex:IM-20758 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16026344|imex:IM-20758-5|dip:DIP-190437E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|reactome:R-MMU-6791226|dip:DIP-60112N|refseq:NP_080343.4 ensembl:ENSMUSG00000037296(gene)|ensembl:ENSMUST00000038421(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-MMU-430039|dip:DIP-60113N|refseq:NP_080308.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/07 2017/08/10 rogid:7a1LEh8uXxhti4YylOhiX6dkO3I10090 rogid:aWdeQ47hMdnvLy9DKXHb7PBkI0s10090 rigid:KBApjUBNL0nBzR21ZpY6e7CSEpY false green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)