#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9U6B8 uniprotkb:Q9U6B8 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:"MI:0030"(cross-linking study) Hou et al. (2012) pubmed:23180775|doi:10.1126/science.1228757|imex:IM-25204 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16025091|imex:IM-25204-1|dip:DIP-189300E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)") - 2017/08/07 2017/08/10 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rigid:iMQnHFwTZ0HSfV11r/H/E7BcD0s false sufficient binding region:119-351 sufficient binding region:119-351 - 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9U6B8 uniprotkb:Q9U6B8 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:"MI:0071"(molecular sieving) Hou et al. (2012) pubmed:23180775|doi:10.1126/science.1228757|imex:IM-25204 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16025129|imex:IM-25204-3|dip:DIP-189300E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)") - 2017/08/07 2017/08/10 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rigid:iMQnHFwTZ0HSfV11r/H/E7BcD0s false sufficient binding region:132-341 sufficient binding region:132-341 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9U6B8 uniprotkb:Q9U6B8 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:"MI:0114"(x-ray crystallography) Hou et al. (2012) pubmed:23180775|doi:10.1126/science.1228757|imex:IM-25204 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16025111|imex:IM-25204-2|dip:DIP-189300E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)") - 2017/08/07 2017/08/10 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rigid:iMQnHFwTZ0HSfV11r/H/E7BcD0s false sufficient binding region:132-341 sufficient binding region:132-341 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9U6B8 uniprotkb:Q9U6B8 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 intact:EBI-118501|uniprotkb:Q0E937|uniprotkb:Q1HCN1|uniprotkb:Q7JQY5|uniprotkb:Q7KRH6|uniprotkb:Q8IGA6|uniprotkb:Q9V892|uniprotkb:B7YZJ7|ensemblmetazoa:FBpp0085974|ensemblmetazoa:FBpp0085976|ensemblmetazoa:FBpp0307679 psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:crcm1_drome(display_long)|uniprotkb:Orai(gene name)|psi-mi:Orai(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:Protein orai(gene name synonym)|uniprotkb:olf186-F(gene name synonym)|uniprotkb:CG11430(orf name) psi-mi:"MI:0104"(static light scattering) Hou et al. (2012) pubmed:23180775|doi:10.1126/science.1228757|imex:IM-25204 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16025147|imex:IM-25204-4|dip:DIP-189300E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 refseq:NP_001137696.1|refseq:NP_611273.1|refseq:NP_725727.1|flybase:FBgn0041585|refseq:NP_001261063.1|refseq:NP_995881.2|dip:DIP-59770N|ensemblmetazoa:FBgn0041585(gene)|ensemblmetazoa:FBtr0086795(transcript)|ensemblmetazoa:FBtr0086797(transcript)|ensemblmetazoa:FBtr0336698(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:4HKR|rcsb pdb:4HKS|rcsb pdb:6AKI|rcsb pdb:6BBF|rcsb pdb:6BBG|rcsb pdb:6BBH|rcsb pdb:6BBI|rcsb pdb:7KR5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4922(picpa)|taxid:4922("Pichia pastoris (Yeast)") - 2017/08/07 2017/08/10 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rogid:2do1CfhBmXwIWQLURkefHWPpyxA7227 rigid:iMQnHFwTZ0HSfV11r/H/E7BcD0s false sufficient binding region:132-341 sufficient binding region:132-341 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)