#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NXW9 uniprotkb:P42568 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032116|imex:IM-25716-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N - comment:mint - figure legend:Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rigid:MLi6k8pqp/hEPO0PlJZedcvN4Vk false - binding-associated region:10-151 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q09472 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032120|imex:IM-25716-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) - comment:mint - figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 rigid:Cjxc4eq7R5le41BormzMHWR8iB4 false - binding-associated region:1054-1352 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q99613 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032128|imex:IM-25716-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N - comment:mint - figure legend:Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606 rigid:H/Kf7VkmP0IIt4l0n2UNjGXMjmE false - binding-associated region:749-882(IPR000717) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q9Y217 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-766064|uniprotkb:Q5JRG6|uniprotkb:Q86TB7|uniprotkb:Q86YH4|uniprotkb:Q96P80|uniprotkb:B2RBB5|uniprotkb:B3KSB4|ensembl:ENSP00000371221 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:mtmr6_human(display_long)|uniprotkb:MTMR6(gene name)|psi-mi:MTMR6(display_short)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032135|imex:IM-25716-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_004676.3|ensembl:ENSG00000139505(gene)|ensembl:ENST00000381801(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0106018"(phosphatidylinositol-3,5-bisphosphate phosphatase activity)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR030564|interpro:IPR030581|interpro:IPR035998|mint:Q9Y217|rcsb pdb:2YF0|reactome:R-HSA-1660499 - comment:mint - figure legend:Table 1-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:BElxBLRw8vrnpTuAJzkoWEtICVA9606 rigid:qql+rWaXnwUJcJpMFPl6KvKUm+c false - binding-associated region:251-539 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:P60900 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032142|imex:IM-25716-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N - comment:mint - figure legend:Table 1-5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 rigid:g8jheKeayqxiq1F2iM0Qwy2TlzY false - binding-associated region:11-232 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q99613 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032192|imex:IM-25716-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N - comment:mint - figure legend:Table 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606 rigid:H/Kf7VkmP0IIt4l0n2UNjGXMjmE false - binding-associated region:749-882(IPR000717) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q09472 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032186|imex:IM-25716-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) - comment:mint - figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 rigid:Cjxc4eq7R5le41BormzMHWR8iB4 false - binding-associated region:1054-1352 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q03111 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-1384215|uniprotkb:Q14768|ensembl:ENSP00000252674 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:enl_human(display_long)|uniprotkb:MLLT1(gene name)|psi-mi:MLLT1(display_short)|uniprotkb:ENL(gene name synonym)|uniprotkb:LTG19(gene name synonym)|uniprotkb:YEATS1(gene name synonym)|uniprotkb:YEATS domain-containing protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032164|imex:IM-25716-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_005925.2|ensembl:ENSG00000130382(gene)|ensembl:ENST00000252674(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008023"(transcription elongation factor complex)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|rcsb pdb:5J9S|rcsb pdb:6HPW|rcsb pdb:6HPX|rcsb pdb:6HPY|rcsb pdb:6HPZ|rcsb pdb:6HQ0|rcsb pdb:6HT0|rcsb pdb:6HT1|rcsb pdb:6T1I|rcsb pdb:6T1J|rcsb pdb:6T1L|rcsb pdb:6T1M|rcsb pdb:6T1N|rcsb pdb:6T1O|rcsb pdb:7B0T|rcsb pdb:7B10|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955 - comment:mint - figure legend:Table 1i|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:H+j5XCIlsBwjsia+gMfTFKev3mA9606 rigid:B2RSB6uDxIgQMTiVbz5m/ErkPmM false - binding-associated region:4-151 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q15911 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-2849611|uniprotkb:Q13719|uniprotkb:O15101|uniprotkb:Q6ZP98|uniprotkb:D3DWS8|intact:EBI-28968693|ensembl:ENSP00000268489|ensembl:ENSP00000493252 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:zfhx3_human(display_long)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032176|imex:IM-25716-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 ensembl:ENSP00000268489|ensembl:ENST00000397992|ensembl:ENSP00000438926|ensembl:ENSP00000493252|refseq:NP_001158238.1|refseq:NP_008816.3|ensembl:ENSG00000140836(gene)|ensembl:ENST00000268489(transcript)|ensembl:ENST00000641206(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001356(Homeobox)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017970|interpro:IPR036236|rcsb pdb:2DA1|rcsb pdb:2DA2|rcsb pdb:2DA3|reactome:R-HSA-8941855|refseq:NP_997268.1|refseq:XP_016878717.1|refseq:XP_016878718.1 - comment:mint - figure legend:Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:PCTLSDb8//3KuRhpHykw3cIIJOg9606 rigid:GpMZS/uXPkPOI1pHa7TlB9pcI2Y false - binding-associated region:1545-1626(IPR013087) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q9ULV5 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-766428|uniprotkb:Q99472|uniprotkb:Q9ULV6|ensembl:ENSP00000430947 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:hsf4_human(display_long)|uniprotkb:Heat shock transcription factor 4(gene name synonym)|uniprotkb:HSF4(gene name)|psi-mi:HSF4(display_short) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032206|imex:IM-25716-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001035757.1|refseq:NP_001529.2|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:6J6V|rcsb pdb:6J6W|ensembl:ENSG00000102878(gene)|ensembl:ENST00000521374(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II) - comment:mint - figure legend:Table 1ii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:a93s7Ye3QI/91xU1vhBEOH9p4rU9606 rigid:x3d6E/wbFmX5B3OjS65I6YEYbiQ false - binding-associated region:1-93 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q9UGI8 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-2561654|uniprotkb:Q9HAJ9|uniprotkb:Q9GZQ1|uniprotkb:A4D0U6|ensembl:ENSP00000350937 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:tes_human(display_long)|uniprotkb:TESS(gene name synonym)|uniprotkb:TES(gene name)|psi-mi:TES(display_short) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032212|imex:IM-25716-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_056456.1|refseq:NP_690042.1|ensembl:ENSG00000135269(gene)|ensembl:ENST00000358204(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR027683|interpro:IPR033724|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960|mint:Q9UGI8|rcsb pdb:2IYB|rcsb pdb:2XQN - comment:mint - figure legend:Table 1iii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:19bO7/55OMgcMT5lx1404AluskE9606 rigid:nLw4zznhwMaIuT3s4n563KJXOZA false - binding-associated region:1-375 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q09472 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032252|imex:IM-25716-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) - comment:mint - figure legend:Table 1-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 rigid:Cjxc4eq7R5le41BormzMHWR8iB4 false mutation:169-169,171-171 binding-associated region:1054-1352 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q9ULV5 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-766428|uniprotkb:Q99472|uniprotkb:Q9ULV6|ensembl:ENSP00000430947 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:hsf4_human(display_long)|uniprotkb:Heat shock transcription factor 4(gene name synonym)|uniprotkb:HSF4(gene name)|psi-mi:HSF4(display_short) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032233|imex:IM-25716-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001035757.1|refseq:NP_001529.2|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|interpro:IPR027725|interpro:IPR036388|interpro:IPR036390|rcsb pdb:6J6V|rcsb pdb:6J6W|ensembl:ENSG00000102878(gene)|ensembl:ENST00000521374(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II) - comment:mint - figure legend:Table 1ii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:a93s7Ye3QI/91xU1vhBEOH9p4rU9606 rigid:x3d6E/wbFmX5B3OjS65I6YEYbiQ false mutation:171-171,169-169 binding-associated region:1-93 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q9UGI8 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-2561654|uniprotkb:Q9HAJ9|uniprotkb:Q9GZQ1|uniprotkb:A4D0U6|ensembl:ENSP00000350937 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:tes_human(display_long)|uniprotkb:TESS(gene name synonym)|uniprotkb:TES(gene name)|psi-mi:TES(display_short) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032239|imex:IM-25716-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_056456.1|refseq:NP_690042.1|ensembl:ENSG00000135269(gene)|ensembl:ENST00000358204(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR027683|interpro:IPR033724|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960|mint:Q9UGI8|rcsb pdb:2IYB|rcsb pdb:2XQN - comment:mint - figure legend:Table 1iii|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:19bO7/55OMgcMT5lx1404AluskE9606 rigid:nLw4zznhwMaIuT3s4n563KJXOZA false mutation:169-169,171-171 binding-associated region:1-375 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:Q15911 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-2849611|uniprotkb:Q13719|uniprotkb:O15101|uniprotkb:Q6ZP98|uniprotkb:D3DWS8|intact:EBI-28968693|ensembl:ENSP00000268489|ensembl:ENSP00000493252 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:zfhx3_human(display_long)|uniprotkb:AT motif-binding factor 1(gene name synonym)|uniprotkb:ZFHX3(gene name)|psi-mi:ZFHX3(display_short)|uniprotkb:ATBF1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:C16orf47(gene name synonym) psi-mi:"MI:0018"(two hybrid) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-14032245|imex:IM-25716-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 ensembl:ENSP00000268489|ensembl:ENST00000397992|ensembl:ENSP00000438926|ensembl:ENSP00000493252|refseq:NP_001158238.1|refseq:NP_008816.3|ensembl:ENSG00000140836(gene)|ensembl:ENST00000268489(transcript)|ensembl:ENST00000641206(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR001356(Homeobox)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017970|interpro:IPR036236|rcsb pdb:2DA1|rcsb pdb:2DA2|rcsb pdb:2DA3|reactome:R-HSA-8941855|refseq:NP_997268.1|refseq:XP_016878717.1|refseq:XP_016878718.1 - comment:mint - figure legend:Table 1-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:PCTLSDb8//3KuRhpHykw3cIIJOg9606 rigid:GpMZS/uXPkPOI1pHa7TlB9pcI2Y false mutation:169-169,171-171 binding-associated region:1545-1626(IPR013087) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NXW9 uniprotkb:P42568 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-716132|uniprotkb:B1AMQ2|uniprotkb:D3DRJ8|intact:EBI-11060385|ensembl:ENSP00000369695|intact:EBI-749963|uniprotkb:B2R7B3|uniprotkb:B7Z755|uniprotkb:Q8IVB0 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:af9_human(display_long)|uniprotkb:ALL1-fused gene from chromosome 9 protein(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein(gene name synonym)|uniprotkb:YEATS domain-containing protein 3(gene name synonym)|uniprotkb:MLLT3(gene name)|psi-mi:MLLT3(display_short)|uniprotkb:AF9(gene name synonym)|uniprotkb:YEATS3(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-14032294|imex:IM-25716-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_004520.2|refseq:NP_001273620.1|ensembl:ENSG00000171843(gene)|ensembl:ENST00000380338(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007379"(segment specification)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010467"(gene expression)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|mint:P42568|rcsb pdb:2LM0|rcsb pdb:2MV7|rcsb pdb:2N4Q|rcsb pdb:2NDF|rcsb pdb:2NDG|rcsb pdb:4TMP|rcsb pdb:5HJB|rcsb pdb:5HJD|rcsb pdb:5YYF|rcsb pdb:6B7G|rcsb pdb:6L5Z|rcsb pdb:6LS6|rcsb pdb:6MIL|rcsb pdb:6MIM|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|dip:DIP-56409N go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus) comment:mint - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:Z+g2iDUI+CzIrL7bMjY11hYKywQ9606 rigid:MLi6k8pqp/hEPO0PlJZedcvN4Vk false cyan fluorescent protein tag:c-c yellow fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NXW9 uniprotkb:Q03111 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-1384215|uniprotkb:Q14768|ensembl:ENSP00000252674 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:enl_human(display_long)|uniprotkb:MLLT1(gene name)|psi-mi:MLLT1(display_short)|uniprotkb:ENL(gene name synonym)|uniprotkb:LTG19(gene name synonym)|uniprotkb:YEATS1(gene name synonym)|uniprotkb:YEATS domain-containing protein 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-14032302|imex:IM-25716-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_005925.2|ensembl:ENSG00000130382(gene)|ensembl:ENST00000252674(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008023"(transcription elongation factor complex)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|rcsb pdb:5J9S|rcsb pdb:6HPW|rcsb pdb:6HPX|rcsb pdb:6HPY|rcsb pdb:6HPZ|rcsb pdb:6HQ0|rcsb pdb:6HT0|rcsb pdb:6HT1|rcsb pdb:6T1I|rcsb pdb:6T1J|rcsb pdb:6T1L|rcsb pdb:6T1M|rcsb pdb:6T1N|rcsb pdb:6T1O|rcsb pdb:7B0T|rcsb pdb:7B10|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955 go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus) comment:mint - figure legend:2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:H+j5XCIlsBwjsia+gMfTFKev3mA9606 rigid:B2RSB6uDxIgQMTiVbz5m/ErkPmM false cyan fluorescent protein tag:c-c yellow fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NXW9 uniprotkb:Q03111 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-1384215|uniprotkb:Q14768|ensembl:ENSP00000252674 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:enl_human(display_long)|uniprotkb:MLLT1(gene name)|psi-mi:MLLT1(display_short)|uniprotkb:ENL(gene name synonym)|uniprotkb:LTG19(gene name synonym)|uniprotkb:YEATS1(gene name synonym)|uniprotkb:YEATS domain-containing protein 1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-14032314|imex:IM-25716-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_005925.2|ensembl:ENSG00000130382(gene)|ensembl:ENST00000252674(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008023"(transcription elongation factor complex)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|rcsb pdb:5J9S|rcsb pdb:6HPW|rcsb pdb:6HPX|rcsb pdb:6HPY|rcsb pdb:6HPZ|rcsb pdb:6HQ0|rcsb pdb:6HT0|rcsb pdb:6HT1|rcsb pdb:6T1I|rcsb pdb:6T1J|rcsb pdb:6T1L|rcsb pdb:6T1M|rcsb pdb:6T1N|rcsb pdb:6T1O|rcsb pdb:7B0T|rcsb pdb:7B10|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955 go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus) comment:mint - figure legend:"2D (E)"|comment:Deletion of the YEATS domain strongly reduced the co-localization of ENL with ALKBH4 in nucleoli.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:H+j5XCIlsBwjsia+gMfTFKev3mA9606 rigid:B2RSB6uDxIgQMTiVbz5m/ErkPmM false cyan fluorescent protein tag:c-c yellow fluorescent protein tag:n-n|sufficient binding region:1-141(IPR005033) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NXW9 uniprotkb:Q09472 intact:EBI-8637516|ensembl:ENSP00000292566|uniprotkb:Q9H6A4|uniprotkb:Q53H92|intact:MINT-8162695 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:alkb4_human(display_long)|uniprotkb:ALKBH4(gene name)|psi-mi:ALKBH4(display_short)|uniprotkb:ABH4(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 4(gene name synonym)|uniprotkb:DNA N6-methyl adenine demethylase ALKBH4(gene name synonym)|uniprotkb:Lysine-specific demethylase ALKBH4(gene name synonym) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Bjørnstad et al. (2011) pubmed:23145062|imex:IM-25716 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-14032328|imex:IM-25716-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006482"(protein demethylation)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032451"(demethylase activity)|go:"GO:0035516"(oxidative DNA demethylase activity)|go:"GO:0036090"(cleavage furrow ingression)|go:"GO:0046872"(metal ion binding)|go:"GO:0070938"(contractile ring)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR032857|ensembl:ENSG00000160993(gene)|ensembl:ENST00000292566(transcript)|go:"GO:0003779"(actin binding)|refseq:XP_005250521.1|refseq:NP_060091.1 refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) go:"GO:0005730"(nucleolus) comment:mint - figure legend:2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2017/03/14 2017/04/13 rogid:ntK9qtExDVxIVMu4nG5U8NP8OI89606 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 rigid:Cjxc4eq7R5le41BormzMHWR8iB4 false cyan fluorescent protein tag:c-c yellow fluorescent protein tag:n-n|sufficient binding region:1039-1285(IPR005033)|tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)