#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38182	uniprotkb:P40344	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	intact:EBI-3381|uniprotkb:D6W1I2|ensemblfungi:YNR007C	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:atg3_yeast(display_long)|uniprotkb:Autophagy-related E2-like conjugation enzyme ATG3(gene name synonym)|uniprotkb:ATG3(gene name)|psi-mi:ATG3(display_short)|uniprotkb:AUT1(gene name synonym)|uniprotkb:YNR007C(locus name)|uniprotkb:N2040(orf name)|uniprotkb:APG3(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0195"(covalent binding)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022243|imex:IM-20612-1|dip:DIP-2254E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	sgd:S000005290|refseq:NP_014404.3|dip:DIP-1190N|mint:P40344|ensemblfungi:YNR007C(gene)|ensemblfungi:YNR007C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|rcsb pdb:2DYT|rcsb pdb:3T7G|rcsb pdb:4GSL|rcsb pdb:6OJJ|reactome:R-SCE-1632852	psi-mi:"MI:0465"(dip)	crc64:1246CEFF5A038819	crc64:52CCFB216B18CF0C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rogid:LLgDB7xi+ynGqu140MvZGSaAAXM559292	rigid:yZnASWJR1L/DueRDsBVpr1YrySA	false	-	mutation disrupting interaction strength:73-73,72-72,168-168	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40344	uniprotkb:P38862	intact:EBI-3381|uniprotkb:D6W1I2|ensemblfungi:YNR007C	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	psi-mi:atg3_yeast(display_long)|uniprotkb:Autophagy-related E2-like conjugation enzyme ATG3(gene name synonym)|uniprotkb:ATG3(gene name)|psi-mi:ATG3(display_short)|uniprotkb:AUT1(gene name synonym)|uniprotkb:YNR007C(locus name)|uniprotkb:N2040(orf name)|uniprotkb:APG3(gene name synonym)	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022299|imex:IM-20612-3|dip:DIP-1395E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005290|refseq:NP_014404.3|dip:DIP-1190N|mint:P40344|ensemblfungi:YNR007C(gene)|ensemblfungi:YNR007C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|rcsb pdb:2DYT|rcsb pdb:3T7G|rcsb pdb:4GSL|rcsb pdb:6OJJ|reactome:R-SCE-1632852	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	psi-mi:"MI:0465"(dip)	crc64:52CCFB216B18CF0C	crc64:561EEC94F0ED57F5	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:LLgDB7xi+ynGqu140MvZGSaAAXM559292	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	rigid:hxbh4sDnO48sgxAAiqyJbJGdkyo	false	mutation:83-83,76-76,41-41	binding-associated region:289-630	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40344	uniprotkb:P38862	intact:EBI-3381|uniprotkb:D6W1I2|ensemblfungi:YNR007C	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	psi-mi:atg3_yeast(display_long)|uniprotkb:Autophagy-related E2-like conjugation enzyme ATG3(gene name synonym)|uniprotkb:ATG3(gene name)|psi-mi:ATG3(display_short)|uniprotkb:AUT1(gene name synonym)|uniprotkb:YNR007C(locus name)|uniprotkb:N2040(orf name)|uniprotkb:APG3(gene name synonym)	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022323|imex:IM-20612-4|dip:DIP-1395E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005290|refseq:NP_014404.3|dip:DIP-1190N|mint:P40344|ensemblfungi:YNR007C(gene)|ensemblfungi:YNR007C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000153"(cytoplasmic ubiquitin ligase complex)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0019776"(Atg8 ligase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061908"(phagophore)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|rcsb pdb:2DYT|rcsb pdb:3T7G|rcsb pdb:4GSL|rcsb pdb:6OJJ|reactome:R-SCE-1632852	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	psi-mi:"MI:0465"(dip)	crc64:52CCFB216B18CF0C	crc64:561EEC94F0ED57F5	comment:Deletion of region 290-294 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:LLgDB7xi+ynGqu140MvZGSaAAXM559292	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	rigid:hxbh4sDnO48sgxAAiqyJbJGdkyo	false	mutation:83-83,76-76,41-41	mutation disrupting interaction strength:507-507|mutation decreasing interaction strength:283-283|mutation decreasing interaction strength:285-285|mutation decreasing interaction strength:291-292|mutation decreasing interaction strength:18-18,16-16,14-14|mutation decreasing interaction strength:61-61,16-16	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38862	uniprotkb:P38182	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0195"(covalent binding)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022366|imex:IM-20612-5|dip:DIP-1396E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	psi-mi:"MI:0465"(dip)	crc64:561EEC94F0ED57F5	crc64:1246CEFF5A038819	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rigid:bCCYMWljJ3XQjAtfTEdBB+3y5mU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07879	uniprotkb:P38862	intact:EBI-36629|uniprotkb:D6VXW4|ensemblfungi:YLL042C	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	psi-mi:atg10_yeast(display_long)|uniprotkb:Autophagy-related protein 10(gene name synonym)|uniprotkb:ATG10(gene name)|psi-mi:ATG10(display_short)|uniprotkb:YLL042C(locus name)|uniprotkb:APG10(gene name synonym)	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022383|imex:IM-20612-6|dip:DIP-138391E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013058.1|sgd:S000003965|dip:DIP-4842N|ensemblfungi:YLL042C(gene)|ensemblfungi:YLL042C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|interpro:IPR016524(Autophagy-related protein 10)|rcsb pdb:4EBR|rcsb pdb:4GSK|go:"GO:0016236"(macroautophagy)	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	psi-mi:"MI:0465"(dip)	crc64:9B90684B8D3D26C5	crc64:561EEC94F0ED57F5	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:+lfjt82mgvlrDUJWl9OqbgiwH9Q559292	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	rigid:M1dSllPW+UEx3q1OnCQpjglNuo0	false	mutation:26-26,137-137	binding-associated region:289-630	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07879	uniprotkb:P38862	intact:EBI-36629|uniprotkb:D6VXW4|ensemblfungi:YLL042C	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	psi-mi:atg10_yeast(display_long)|uniprotkb:Autophagy-related protein 10(gene name synonym)|uniprotkb:ATG10(gene name)|psi-mi:ATG10(display_short)|uniprotkb:YLL042C(locus name)|uniprotkb:APG10(gene name synonym)	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022406|imex:IM-20612-7|dip:DIP-138391E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013058.1|sgd:S000003965|dip:DIP-4842N|ensemblfungi:YLL042C(gene)|ensemblfungi:YLL042C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|interpro:IPR016524(Autophagy-related protein 10)|rcsb pdb:4EBR|rcsb pdb:4GSK|go:"GO:0016236"(macroautophagy)	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	psi-mi:"MI:0465"(dip)	crc64:9B90684B8D3D26C5	crc64:561EEC94F0ED57F5	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:+lfjt82mgvlrDUJWl9OqbgiwH9Q559292	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	rigid:M1dSllPW+UEx3q1OnCQpjglNuo0	false	mutation:26-26,137-137|necessary binding region:86-93	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07879	uniprotkb:P38862	intact:EBI-36629|uniprotkb:D6VXW4|ensemblfungi:YLL042C	intact:EBI-2677|uniprotkb:D3DLC0|ensemblfungi:YHR171W	psi-mi:atg10_yeast(display_long)|uniprotkb:Autophagy-related protein 10(gene name synonym)|uniprotkb:ATG10(gene name)|psi-mi:ATG10(display_short)|uniprotkb:YLL042C(locus name)|uniprotkb:APG10(gene name synonym)	psi-mi:atg7_yeast(display_long)|uniprotkb:ATG7(gene name)|psi-mi:ATG7(display_short)|uniprotkb:APG7(gene name synonym)|uniprotkb:CVT2(gene name synonym)|uniprotkb:ATG12-activating enzyme E1 ATG7(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 2(gene name synonym)|uniprotkb:Autophagy-related protein 7(gene name synonym)|uniprotkb:YHR171W(locus name)	psi-mi:"MI:0030"(cross-linking study)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022265|imex:IM-20612-2|dip:DIP-138391E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013058.1|sgd:S000003965|dip:DIP-4842N|ensemblfungi:YLL042C(gene)|ensemblfungi:YLL042C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|interpro:IPR016524(Autophagy-related protein 10)|rcsb pdb:4EBR|rcsb pdb:4GSK|go:"GO:0016236"(macroautophagy)	sgd:S000001214|refseq:NP_012041.1|reactome:R-SCE-1632852|reactome:R-SCE-6798695|dip:DIP-1196N|ensemblfungi:YHR171W(gene)|ensemblfungi:YHR171W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006501"(C-terminal protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019778"(Atg12 activating enzyme activity)|go:"GO:0019779"(Atg8 activating enzyme activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR006285(E1-like protein-activating enzyme Gsa7p/Apg7p)|interpro:IPR032197|interpro:IPR035985|interpro:IPR042522|interpro:IPR042523|rcsb pdb:2LI5|rcsb pdb:3RUI|rcsb pdb:3RUJ|rcsb pdb:3T7E|rcsb pdb:3T7F|rcsb pdb:3T7G|rcsb pdb:3T7H|rcsb pdb:3VH1|rcsb pdb:3VH2|reactome:R-SCE-983168|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:4GSJ|rcsb pdb:4GSK|rcsb pdb:4GSL|rcsb pdb:5YEC	psi-mi:"MI:0465"(dip)	crc64:9B90684B8D3D26C5	crc64:561EEC94F0ED57F5	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:+lfjt82mgvlrDUJWl9OqbgiwH9Q559292	rogid:d9sYZJRVHd00XhEjw0xjYrlL0NE559292	rigid:M1dSllPW+UEx3q1OnCQpjglNuo0	false	mutation:26-26,137-137	mutation decreasing interaction strength:291-292|necessary binding region:290-294|mutation disrupting interaction strength:507-507|mutation disrupting interaction strength:285-285|mutation decreasing interaction strength:137-137	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07879	uniprotkb:P38182	intact:EBI-36629|uniprotkb:D6VXW4|ensemblfungi:YLL042C	intact:EBI-2684|uniprotkb:D6VPS5|ensemblfungi:YBL078C	psi-mi:atg10_yeast(display_long)|uniprotkb:Autophagy-related protein 10(gene name synonym)|uniprotkb:ATG10(gene name)|psi-mi:ATG10(display_short)|uniprotkb:YLL042C(locus name)|uniprotkb:APG10(gene name synonym)	psi-mi:atg8_yeast(display_long)|uniprotkb:ATG8(gene name)|psi-mi:ATG8(display_short)|uniprotkb:APG8(gene name synonym)|uniprotkb:AUT7(gene name synonym)|uniprotkb:YBL078C(locus name)|uniprotkb:YBL0732(orf name)|uniprotkb:CVT5(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier ATG8(gene name synonym)|uniprotkb:Cytoplasm to vacuole targeting protein 5(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Kaiser et al. (2012)	pubmed:23142976|doi:10.1038/nsmb.2415|imex:IM-20612	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0195"(covalent binding)	psi-mi:"MI:0465"(DIP)	intact:EBI-16022429|imex:IM-20612-8|dip:DIP-190185E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013058.1|sgd:S000003965|dip:DIP-4842N|ensemblfungi:YLL042C(gene)|ensemblfungi:YLL042C_mRNA(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0019777"(Atg12 transferase activity)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR007135(Autophagocytosis associated protein, C-terminal)|interpro:IPR016524(Autophagy-related protein 10)|rcsb pdb:4EBR|rcsb pdb:4GSK|go:"GO:0016236"(macroautophagy)	sgd:S000000174|refseq:NP_009475.1|dip:DIP-1197N|mint:P38182|ensemblfungi:YBL078C(gene)|ensemblfungi:YBL078C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031386"(protein tag)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0033110"(Cvt vesicle membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034629"|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061025"(membrane fusion)|go:"GO:0061709"(reticulophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1905153"(regulation of membrane invagination)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:2KQ7|rcsb pdb:2KWC|rcsb pdb:2LI5|rcsb pdb:2ZPN|rcsb pdb:3RUI|rcsb pdb:3VH3|rcsb pdb:3VH4|rcsb pdb:3VXW|rcsb pdb:5YEC|rcsb pdb:6AAG|rcsb pdb:6WY6|rcsb pdb:7BRN|reactome:R-SCE-1632852|reactome:R-SCE-8854214|reactome:R-SCE-8934903	psi-mi:"MI:0465"(dip)	crc64:9B90684B8D3D26C5	crc64:1246CEFF5A038819	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:+lfjt82mgvlrDUJWl9OqbgiwH9Q559292	rogid:UlmpBW3JgdYFHLkZCQeJeb7DpK4559292	rigid:TO9uJv0ZSYZpDNbJeba7vTriAUs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)