#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38247 uniprotkb:P38247 intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16021214|imex:IM-20603-1|dip:DIP-190159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:D64ABDE1CDF265FD crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:zxxKtLs+9IR+cc4fwtL6YKlZji8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38247 uniprotkb:P38247 intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16021280|imex:IM-20603-4|dip:DIP-190159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:D64ABDE1CDF265FD crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:zxxKtLs+9IR+cc4fwtL6YKlZji8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:Q00582 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16021257|imex:IM-20603-3|dip:DIP-6888E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0465"(dip) crc64:0A0D16C81F73184D crc64:B79CE7FE7AD2FDBE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rigid:LVXxv4cLIEbNVWFQnXnwzP/YAus false v5 tag:c-c tandem tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53290 uniprotkb:P38247 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16021230|imex:IM-20603-2|dip:DIP-190160E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:0A0D16C81F73184D crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:RuiZnRjeeeoPTYgV/6eU40FALoE false - necessary binding region:1-17|necessary binding region:21-30|mutation decreasing interaction strength:71-71,70-70,68-68,67-67 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38247 uniprotkb:Q00582 intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16021367|imex:IM-20603-8|dip:DIP-125890E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0465"(dip) crc64:D64ABDE1CDF265FD crc64:B79CE7FE7AD2FDBE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rigid:5Uz2fclUqECnT3JNoK8c5THRvFg false green fluorescent protein tag:c-c|mutation decreasing interaction strength:71-71,70-70,68-68,67-67 tandem tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00582 uniprotkb:P53290 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:"MI:0096"(pull down) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16021340|imex:IM-20603-7|dip:DIP-190161E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 psi-mi:"MI:0465"(dip) crc64:B79CE7FE7AD2FDBE crc64:0A0D16C81F73184D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rigid:ufYb2tYEDJu9okDswWyJ6G8XlBI false tandem tag:c-c v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00582 uniprotkb:P38247 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16021340|imex:IM-20603-7|dip:DIP-190161E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:B79CE7FE7AD2FDBE crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:ufYb2tYEDJu9okDswWyJ6G8XlBI false tandem tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q00582 uniprotkb:Q02205 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16021340|imex:IM-20603-7|dip:DIP-190161E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:B79CE7FE7AD2FDBE crc64:995DD1E68331D050 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rigid:ufYb2tYEDJu9okDswWyJ6G8XlBI false tandem tag:c-c glutathione s tranferase tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38247 uniprotkb:P38247 intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16021323|imex:IM-20603-6|dip:DIP-190159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:D64ABDE1CDF265FD crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:4tTdH+/RcjuTZ+ZXTWNpgHaf/Zc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:P38247 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16021296|imex:IM-20603-5|dip:DIP-125890E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288 refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:B79CE7FE7AD2FDBE crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:5Uz2fclUqECnT3JNoK8c5THRvFg false - necessary binding region:1-17|necessary binding region:21-30|mutation decreasing interaction strength:71-71,70-70,68-68,67-67 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02205 uniprotkb:P38247 intact:EBI-27062|uniprotkb:D6VX73|ensemblfungi:YKR007W intact:EBI-21507|uniprotkb:D6VQ76|ensemblfungi:YBR077C psi-mi:meh1_yeast(display_long)|uniprotkb:GSE complex subunit 2(gene name synonym)|uniprotkb:EGO complex subunit 1(gene name synonym)|uniprotkb:YKR007W(locus name)|uniprotkb:YK106(orf name)|uniprotkb:MEH1(gene name)|psi-mi:MEH1(display_short)|uniprotkb:EGO1(gene name synonym)|uniprotkb:GSE2(gene name synonym) psi-mi:slm4_yeast(display_long)|uniprotkb:YBR077C(locus name)|uniprotkb:YBR0723(orf name)|uniprotkb:GSE complex subunit 1(gene name synonym)|uniprotkb:EGO complex subunit 3(gene name synonym)|uniprotkb:SLM4(gene name)|psi-mi:SLM4(display_short)|uniprotkb:EGO3(gene name synonym)|uniprotkb:GSE1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Zhang et al. (2012) pubmed:23123112|doi:10.1016/j.str.2012.09.019|imex:IM-20603 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16021394|imex:IM-20603-9|dip:DIP-2126E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001715|refseq:NP_012932.1|mint:Q02205|dip:DIP-1922N|ensemblfungi:YKR007W(gene)|ensemblfungi:YKR007W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005829"(cytosol)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007040"(lysosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:0072665"(protein localization to vacuole)|interpro:IPR028209|rcsb pdb:4XPM|rcsb pdb:6JWP refseq:NP_009633.3|sgd:S000000281|mint:P38247|dip:DIP-1763N|ensemblfungi:YBR077C(gene)|ensemblfungi:YBR077C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0071986"(Ragulator complex)|interpro:IPR020233|rcsb pdb:3LGO|rcsb pdb:4FTX|rcsb pdb:4FUW|rcsb pdb:4XPM|rcsb pdb:6JWP psi-mi:"MI:0465"(dip) crc64:995DD1E68331D050 crc64:D64ABDE1CDF265FD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:73a6e5W5wQixGg2aGXDo4A6NR2s559292 rogid:BCEWjA3PQvwm3n08QwY0D//TpbA559292 rigid:1agN6J4PcldSswPiG17ZcKgJtgQ false - necessary binding region:1-17|necessary binding region:21-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)