#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q4QEN5 uniprotkb:Q4Q3K2 intact:EBI-16019427|ensemblprotists:CAJ04011|ensemblprotists:CAJ04013|uniprotkb:A0PJ38 intact:EBI-16019391|ensemblprotists:CAJ07706 psi-mi:q4qen5_leima(display_long)|uniprotkb:LMJF_16_1310(orf name)|uniprotkb:LMJF_16_1320(orf name) psi-mi:q4q3k2_leima(display_long)|uniprotkb:APX(gene name)|psi-mi:APX(display_short)|uniprotkb:LMJF_34_0070(orf name) psi-mi:"MI:0114"(x-ray crystallography) Jasion et al. (2012) pubmed:23100535|doi:10.1073/pnas.1213295109|imex:IM-21288 taxid:5664(leima)|taxid:5664(Leishmania major) taxid:5664(leima)|taxid:5664(Leishmania major) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16019448|imex:IM-21288-1|dip:DIP-191248E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblprotists:CAJ04011(transcript)|ensemblprotists:CAJ04013(transcript)|ensemblprotists:LMJF_16_1310(gene)|ensemblprotists:LMJF_16_1320(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:4DY9|rcsb pdb:4GED|refseq:XP_001682212.1|refseq:XP_001682213.1|dip:DIP-60329N ensemblprotists:CAJ07706(transcript)|ensemblprotists:LMJF_34_0070(gene)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0004447"(iodide peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0008447"(L-ascorbate oxidase activity)|go:"GO:0016688"(L-ascorbate peroxidase activity)|go:"GO:0020037"(heme binding)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031304"(intrinsic component of mitochondrial inner membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042493"|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019794|interpro:IPR044831|rcsb pdb:3RIV|rcsb pdb:3RIW|rcsb pdb:4GED|rcsb pdb:5AL9|rcsb pdb:5ALA|rcsb pdb:5AMM|refseq:XP_001686096.1|dip:DIP-60328N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:AltjwFNZi9ADICmkLaMPZ0vZPX45664 rogid:kMh4AWuOEfqX7DXVuYXMBNvhNSo5664 rigid:XptdNi/zwtjIVI9u1NRu3kZU21M false sufficient binding region:11-113 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q4QEN5 uniprotkb:Q4Q3K2 intact:EBI-16019427|ensemblprotists:CAJ04011|ensemblprotists:CAJ04013|uniprotkb:A0PJ38 intact:EBI-16019391|ensemblprotists:CAJ07706 psi-mi:q4qen5_leima(display_long)|uniprotkb:LMJF_16_1310(orf name)|uniprotkb:LMJF_16_1320(orf name) psi-mi:q4q3k2_leima(display_long)|uniprotkb:APX(gene name)|psi-mi:APX(display_short)|uniprotkb:LMJF_34_0070(orf name) psi-mi:"MI:0979"(oxidoreductase assay) Jasion et al. (2012) pubmed:23100535|doi:10.1073/pnas.1213295109|imex:IM-21288 taxid:5664(leima)|taxid:5664(Leishmania major) taxid:5664(leima)|taxid:5664(Leishmania major) psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16019467|imex:IM-21288-2|dip:DIP-191248E - - psi-mi:"MI:0579"(electron donor) psi-mi:"MI:0580"(electron acceptor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblprotists:CAJ04011(transcript)|ensemblprotists:CAJ04013(transcript)|ensemblprotists:LMJF_16_1310(gene)|ensemblprotists:LMJF_16_1320(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|rcsb pdb:4DY9|rcsb pdb:4GED|refseq:XP_001682212.1|refseq:XP_001682213.1|dip:DIP-60329N ensemblprotists:CAJ07706(transcript)|ensemblprotists:LMJF_34_0070(gene)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0004447"(iodide peroxidase activity)|go:"GO:0004601"(peroxidase activity)|go:"GO:0008447"(L-ascorbate oxidase activity)|go:"GO:0016688"(L-ascorbate peroxidase activity)|go:"GO:0020037"(heme binding)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031304"(intrinsic component of mitochondrial inner membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042493"|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR002016(Haem peroxidase, plant/fungal/bacterial)|interpro:IPR002207(Plant ascorbate peroxidase)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019794|interpro:IPR044831|rcsb pdb:3RIV|rcsb pdb:3RIW|rcsb pdb:4GED|rcsb pdb:5AL9|rcsb pdb:5ALA|rcsb pdb:5AMM|refseq:XP_001686096.1|dip:DIP-60328N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:AltjwFNZi9ADICmkLaMPZ0vZPX45664 rogid:kMh4AWuOEfqX7DXVuYXMBNvhNSo5664 rigid:XptdNi/zwtjIVI9u1NRu3kZU21M false sufficient binding region:11-113|mutation decreasing interaction rate:24-24|mutation decreasing interaction rate:98-98,24-24|mutation decreasing interaction rate:98-98 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)