#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-15676185 uniprotkb:Q9Y657 dip:DIP-46328N intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:h3k4me3(display_short)|psi-mi:EBI-15676185(display_long) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yang et al. (2012) pubmed:23077255|doi:10.1073/pnas.1208517109|imex:IM-20723 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16018390|imex:IM-20723-1|dip:DIP-190376E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:awe4qgBC2v2dD6SIgP4/V9XnN+A-2 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:0UvYxW2s19zxqr6QueMckr7sUD8 false sufficient binding region:1-8|N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:27-262 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15676185 uniprotkb:Q9Y657 dip:DIP-46328N intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:h3k4me3(display_short)|psi-mi:EBI-15676185(display_long) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Yang et al. (2012) pubmed:23077255|doi:10.1073/pnas.1208517109|imex:IM-20723 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16018436|imex:IM-20723-3|dip:DIP-190376E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:awe4qgBC2v2dD6SIgP4/V9XnN+A-2 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:0UvYxW2s19zxqr6QueMckr7sUD8 false sufficient binding region:1-8|N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:27-262 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15676185 uniprotkb:Q9Y657 dip:DIP-46328N intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:h3k4me3(display_short)|psi-mi:EBI-15676185(display_long) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Yang et al. (2012) pubmed:23077255|doi:10.1073/pnas.1208517109|imex:IM-20723 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16018413|imex:IM-20723-2|dip:DIP-190376E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:awe4qgBC2v2dD6SIgP4/V9XnN+A-2 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:0UvYxW2s19zxqr6QueMckr7sUD8 false sufficient binding region:1-8|N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:27-262 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15676185 uniprotkb:Q9Y657 dip:DIP-46328N intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:h3k4me3(display_short)|psi-mi:EBI-15676185(display_long) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Yang et al. (2012) pubmed:23077255|doi:10.1073/pnas.1208517109|imex:IM-20723 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16018459|imex:IM-20723-4|dip:DIP-190376E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:awe4qgBC2v2dD6SIgP4/V9XnN+A-2 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:0UvYxW2s19zxqr6QueMckr7sUD8 false N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:27-262|mutation decreasing interaction strength:184-184|mutation decreasing interaction strength:189-189|mutation disrupting interaction strength:184-184|mutation decreasing interaction strength:189-189 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)