#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O00311 uniprotkb:Q9UBU7-1 intact:EBI-374980|uniprotkb:O00558|uniprotkb:Q5T5U5|ensembl:ENSP00000234626|ensembl:ENSP00000393139|uniprotkb:D3DT31 intact:EBI-16017435|ensembl:ENSP00000265728 psi-mi:cdc7_human(display_long)|uniprotkb:CDC7(gene name)|psi-mi:CDC7(display_short)|uniprotkb:CDC7L1(gene name synonym) psi-mi:q9ubu7-1(display_long)|uniprotkb:DBF4(gene name)|psi-mi:DBF4(display_short)|uniprotkb:ASK(gene name synonym)|uniprotkb:DBF4A(gene name synonym)|uniprotkb:ZDBF1(gene name synonym)|uniprotkb:Activator of S phase kinase(gene name synonym)|uniprotkb:Chiffon homolog A(gene name synonym)|uniprotkb:DBF4-type zinc finger-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Hughes et al. (2012) pubmed:23064647|doi:10.1038/nsmb.2404|imex:IM-18613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16017446|imex:IM-18613-1|dip:DIP-190083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5UWR|rcsb pdb:6YA6|rcsb pdb:6YA7|rcsb pdb:6YA8|reactome:R-HSA-176187|reactome:R-HSA-68962|reactome:R-HSA-8953750|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O00311|rcsb pdb:4F99|rcsb pdb:4F9A|rcsb pdb:4F9B|rcsb pdb:4F9C|rcsb pdb:5UWQ|ensembl:ENSG00000097046(gene)|ensembl:ENST00000234626(transcript)|ensembl:ENST00000428239(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|refseq:NP_001127891.1|refseq:NP_001127892.1|refseq:NP_003494.1|refseq:XP_005271298.1|dip:DIP-31728N intact:EBI-372690(isoform-parent)|ensembl:ENSG00000006634(gene)|ensembl:ENST00000265728(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:p5yHRwdn0crHmH8EXAFyM5R0xwM9606 rogid:5F9TIER/fvq3jl6jkMBN/ZBe/Mw9606 rigid:3D1eFavx86W6m7ABGLJ/Cb7ugdI false sufficient binding region:530-574,37-227,360-483 sufficient binding region:210-266|sufficient binding region:288-350|his tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00311 uniprotkb:Q9UBU7-1 intact:EBI-374980|uniprotkb:O00558|uniprotkb:Q5T5U5|ensembl:ENSP00000234626|ensembl:ENSP00000393139|uniprotkb:D3DT31 intact:EBI-16017435|ensembl:ENSP00000265728 psi-mi:cdc7_human(display_long)|uniprotkb:CDC7(gene name)|psi-mi:CDC7(display_short)|uniprotkb:CDC7L1(gene name synonym) psi-mi:q9ubu7-1(display_long)|uniprotkb:DBF4(gene name)|psi-mi:DBF4(display_short)|uniprotkb:ASK(gene name synonym)|uniprotkb:DBF4A(gene name synonym)|uniprotkb:ZDBF1(gene name synonym)|uniprotkb:Activator of S phase kinase(gene name synonym)|uniprotkb:Chiffon homolog A(gene name synonym)|uniprotkb:DBF4-type zinc finger-containing protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Hughes et al. (2012) pubmed:23064647|doi:10.1038/nsmb.2404|imex:IM-18613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16017479|imex:IM-18613-2|dip:DIP-190083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5UWR|rcsb pdb:6YA6|rcsb pdb:6YA7|rcsb pdb:6YA8|reactome:R-HSA-176187|reactome:R-HSA-68962|reactome:R-HSA-8953750|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O00311|rcsb pdb:4F99|rcsb pdb:4F9A|rcsb pdb:4F9B|rcsb pdb:4F9C|rcsb pdb:5UWQ|ensembl:ENSG00000097046(gene)|ensembl:ENST00000234626(transcript)|ensembl:ENST00000428239(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|refseq:NP_001127891.1|refseq:NP_001127892.1|refseq:NP_003494.1|refseq:XP_005271298.1|dip:DIP-31728N intact:EBI-372690(isoform-parent)|ensembl:ENSG00000006634(gene)|ensembl:ENST00000265728(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:p5yHRwdn0crHmH8EXAFyM5R0xwM9606 rogid:5F9TIER/fvq3jl6jkMBN/ZBe/Mw9606 rigid:3D1eFavx86W6m7ABGLJ/Cb7ugdI false sufficient binding region:530-574,37-227,360-483 sufficient binding region:210-350 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O00311 uniprotkb:Q9UBU7-1 intact:EBI-374980|uniprotkb:O00558|uniprotkb:Q5T5U5|ensembl:ENSP00000234626|ensembl:ENSP00000393139|uniprotkb:D3DT31 intact:EBI-16017435|ensembl:ENSP00000265728 psi-mi:cdc7_human(display_long)|uniprotkb:CDC7(gene name)|psi-mi:CDC7(display_short)|uniprotkb:CDC7L1(gene name synonym) psi-mi:q9ubu7-1(display_long)|uniprotkb:DBF4(gene name)|psi-mi:DBF4(display_short)|uniprotkb:ASK(gene name synonym)|uniprotkb:DBF4A(gene name synonym)|uniprotkb:ZDBF1(gene name synonym)|uniprotkb:Activator of S phase kinase(gene name synonym)|uniprotkb:Chiffon homolog A(gene name synonym)|uniprotkb:DBF4-type zinc finger-containing protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Hughes et al. (2012) pubmed:23064647|doi:10.1038/nsmb.2404|imex:IM-18613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16017502|imex:IM-18613-3|dip:DIP-190083E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5UWR|rcsb pdb:6YA6|rcsb pdb:6YA7|rcsb pdb:6YA8|reactome:R-HSA-176187|reactome:R-HSA-68962|reactome:R-HSA-8953750|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O00311|rcsb pdb:4F99|rcsb pdb:4F9A|rcsb pdb:4F9B|rcsb pdb:4F9C|rcsb pdb:5UWQ|ensembl:ENSG00000097046(gene)|ensembl:ENST00000234626(transcript)|ensembl:ENST00000428239(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|refseq:NP_001127891.1|refseq:NP_001127892.1|refseq:NP_003494.1|refseq:XP_005271298.1|dip:DIP-31728N intact:EBI-372690(isoform-parent)|ensembl:ENSG00000006634(gene)|ensembl:ENST00000265728(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:p5yHRwdn0crHmH8EXAFyM5R0xwM9606 rogid:5F9TIER/fvq3jl6jkMBN/ZBe/Mw9606 rigid:3D1eFavx86W6m7ABGLJ/Cb7ugdI false sufficient binding region:530-574,37-227,360-483 sufficient binding region:210-266|sufficient binding region:288-350 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)