#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12241 uniprotkb:P38959 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20432|uniprotkb:P87334|uniprotkb:Q12011|uniprotkb:D6VS67|ensemblfungi:YDR080W psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vps41_yeast(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:FET2(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 2(gene name synonym)|uniprotkb:VAM2(gene name synonym)|uniprotkb:D446(orf name)|uniprotkb:YD8554.13(orf name)|uniprotkb:YDR080W(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016478|imex:IM-23338-1|dip:DIP-197286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 sgd:S000002487|refseq:NP_010365.3|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001680(WD40 repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322|go:"GO:0035542"(regulation of SNARE complex assembly)|ensemblfungi:YDR080W(gene)|ensemblfungi:YDR080W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0007033"(vacuole organization)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030897"(HOPS complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|dip:DIP-834N psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:E1E48B4D5A1A4005 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:1KML4Bhzf9EYnCcmZ1YUnu0/Pr8559292 rigid:UQU/NML0am5sgA9L6CgpqZ8v0oA false sufficient binding region:1-145|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12241 uniprotkb:P12868 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-6450|uniprotkb:D6W057|ensemblfungi:YMR231W psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:pep5_yeast(display_long)|uniprotkb:PEP5(gene name)|psi-mi:PEP5(display_short)|uniprotkb:END1(gene name synonym)|uniprotkb:Histone E3 ligase PEP5(gene name synonym)|uniprotkb:Vacuolar biogenesis protein END1(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 11(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 1(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 11(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 5(gene name synonym)|uniprotkb:VAM1(gene name synonym)|uniprotkb:VPL9(gene name synonym)|uniprotkb:VPS11(gene name synonym)|uniprotkb:VPT11(gene name synonym)|uniprotkb:YM9959.13(orf name)|uniprotkb:YMR231W(locus name)|uniprotkb:RING-type E3 ubiquitin transferase PEP5(gene name synonym) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016478|imex:IM-23338-1|dip:DIP-197286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_013958.1|sgd:S000004844|mint:P12868|dip:DIP-4409N|ensemblfungi:YMR231W(gene)|ensemblfungi:YMR231W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0036205"(histone catabolic process)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:E5216AD3C285CF34 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:xEGHUcsIIYJCmMvkniYtRd7XE+s559292 rigid:UQU/NML0am5sgA9L6CgpqZ8v0oA false sufficient binding region:1-145|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12241 uniprotkb:P20795 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016478|imex:IM-23338-1|dip:DIP-197286E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:UQU/NML0am5sgA9L6CgpqZ8v0oA false sufficient binding region:1-145|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36015 uniprotkb:P20795 intact:EBI-26982|uniprotkb:D6VX04|ensemblfungi:YKL196C intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:ykt6_yeast(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short)|uniprotkb:YKL196C(locus name) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016543|imex:IM-23338-4|dip:DIP-197290E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-6811438|refseq:NP_012725.1|sgd:S000001679|reactome:R-SCE-6807878|reactome:R-SCE-204005|dip:DIP-2247N|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0031201"(SNARE complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|rcsb pdb:1H8M|rcsb pdb:1IOU|rcsb pdb:3BW6|ensemblfungi:YKL196C(gene)|ensemblfungi:YKL196C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole) sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:9BA0E47ED87B096D crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:+brYspWBpqSSmY9P13pjkQD4gIg559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:3lIyXF0TF8JsXsFt6oK/+A0gpEg false sufficient binding region:1-195|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20795 uniprotkb:Q12241 intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016522|imex:IM-23338-3|dip:DIP-10570E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 psi-mi:"MI:0465"(dip) crc64:ED78DF55109C20E7 crc64:6415D9D852C6C64D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rigid:gv8jqCaAL2AdoIqI+ATskW76TxA false - sufficient binding region:182-264|glutathione s tranferase tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32854 uniprotkb:P20795 intact:EBI-13098|ensemblfungi:YOR036W|uniprotkb:D6W2A3 intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:pep12_yeast(display_long)|uniprotkb:PEP12(gene name)|psi-mi:PEP12(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 13(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 12(gene name synonym)|uniprotkb:VPS6(gene name synonym)|uniprotkb:VPT13(gene name synonym)|uniprotkb:OR26.29(orf name)|uniprotkb:YOR036W(locus name) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016501|imex:IM-23338-2|dip:DIP-197289E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR036W(gene)|ensemblfungi:YOR036W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|refseq:NP_014679.1|sgd:S000005562|mint:P32854|dip:DIP-2021N|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-SCE-204005 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:D9F5711339DA1CDA crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:RAEwrvQSX1rO6JTK4hInPnMkYKU559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:wckgNCKXzGMlKh1ZX6dcAkEvMXU false sufficient binding region:1-268|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20795 uniprotkb:Q12241 intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16016564|imex:IM-23338-5|dip:DIP-10570E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 psi-mi:"MI:0465"(dip) crc64:ED78DF55109C20E7 crc64:6415D9D852C6C64D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rigid:gv8jqCaAL2AdoIqI+ATskW76TxA false - sufficient binding region:182-264|glutathione s tranferase tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32912 uniprotkb:P20795 intact:EBI-20232|uniprotkb:D6VTU3|ensemblfungi:YGL212W intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:vam7_yeast(display_long)|uniprotkb:VAM7(gene name)|psi-mi:VAM7(display_short)|uniprotkb:YGL212W(locus name) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016585|imex:IM-23338-6|dip:DIP-72588E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011303.1|sgd:S000003180|ensemblfungi:YGL212W(gene)|ensemblfungi:YGL212W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0061909"(autophagosome-lysosome fusion)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001683(Phox-like)|interpro:IPR036871|rcsb pdb:1KMD|dip:DIP-1722N|mint:P32912 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:2F992AEC0ACBC8FE crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:RC40scMhwxxJHE4gke72JgkKeh4559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:ExUt0ZEDl+NfhrLUZGH9HqxN5kI false sufficient binding region:190-316|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12241 uniprotkb:Q12255 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-35465|uniprotkb:D6VY93|ensemblfungi:YLR093C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:nyv1_yeast(display_long)|uniprotkb:NYV1(gene name)|psi-mi:NYV1(display_short)|uniprotkb:Synaptobrevin NYV1(gene name synonym)|uniprotkb:New v-SNARE 1(gene name synonym)|uniprotkb:MAM2(gene name synonym)|uniprotkb:YLR093C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016606|imex:IM-23338-7|dip:DIP-188913E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_013194.2|sgd:S000004083|mint:Q12255|dip:DIP-2248N|ensemblfungi:YLR093C(gene)|ensemblfungi:YLR093C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001388(Synaptobrevin)|interpro:IPR019005|interpro:IPR038426|interpro:IPR042855|rcsb pdb:2FZ0|reactome:R-SCE-199992 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:494B587CF0F85997 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:rmpyOWgiP8SZMWZJNLvCQQeWEYw559292 rigid:zvHyP1Ger6gM8BDAlbSg4jbrc0o false sufficient binding region:182-264|glutathione s tranferase tag:c-c sufficient binding region:1-231 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12241 uniprotkb:P32912 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20232|uniprotkb:D6VTU3|ensemblfungi:YGL212W psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vam7_yeast(display_long)|uniprotkb:VAM7(gene name)|psi-mi:VAM7(display_short)|uniprotkb:YGL212W(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016606|imex:IM-23338-7|dip:DIP-188913E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_011303.1|sgd:S000003180|ensemblfungi:YGL212W(gene)|ensemblfungi:YGL212W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0061909"(autophagosome-lysosome fusion)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001683(Phox-like)|interpro:IPR036871|rcsb pdb:1KMD|dip:DIP-1722N|mint:P32912 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:2F992AEC0ACBC8FE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:RC40scMhwxxJHE4gke72JgkKeh4559292 rigid:zvHyP1Ger6gM8BDAlbSg4jbrc0o false sufficient binding region:182-264|glutathione s tranferase tag:c-c sufficient binding region:190-316 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12241 uniprotkb:Q04338 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016606|imex:IM-23338-7|dip:DIP-188913E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:E55B4DA3B40FAD67 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rigid:zvHyP1Ger6gM8BDAlbSg4jbrc0o false sufficient binding region:182-264|glutathione s tranferase tag:c-c sufficient binding region:1-194 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P20795 uniprotkb:Q12241 intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016635|imex:IM-23338-8|dip:DIP-10570E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 psi-mi:"MI:0465"(dip) crc64:ED78DF55109C20E7 crc64:6415D9D852C6C64D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rigid:gv8jqCaAL2AdoIqI+ATskW76TxA false - sufficient binding region:182-243|glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32912 uniprotkb:P20795 intact:EBI-20232|uniprotkb:D6VTU3|ensemblfungi:YGL212W intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:vam7_yeast(display_long)|uniprotkb:VAM7(gene name)|psi-mi:VAM7(display_short)|uniprotkb:YGL212W(locus name) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016729|imex:IM-23338-12|dip:DIP-72588E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011303.1|sgd:S000003180|ensemblfungi:YGL212W(gene)|ensemblfungi:YGL212W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0061909"(autophagosome-lysosome fusion)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001683(Phox-like)|interpro:IPR036871|rcsb pdb:1KMD|dip:DIP-1722N|mint:P32912 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:2F992AEC0ACBC8FE crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:RC40scMhwxxJHE4gke72JgkKeh4559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:ExUt0ZEDl+NfhrLUZGH9HqxN5kI false sufficient binding region:190-316|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12255 uniprotkb:P20795 intact:EBI-35465|uniprotkb:D6VY93|ensemblfungi:YLR093C intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:nyv1_yeast(display_long)|uniprotkb:NYV1(gene name)|psi-mi:NYV1(display_short)|uniprotkb:Synaptobrevin NYV1(gene name synonym)|uniprotkb:New v-SNARE 1(gene name synonym)|uniprotkb:MAM2(gene name synonym)|uniprotkb:YLR093C(locus name) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016708|imex:IM-23338-11|dip:DIP-197288E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013194.2|sgd:S000004083|mint:Q12255|dip:DIP-2248N|ensemblfungi:YLR093C(gene)|ensemblfungi:YLR093C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001388(Synaptobrevin)|interpro:IPR019005|interpro:IPR038426|interpro:IPR042855|rcsb pdb:2FZ0|reactome:R-SCE-199992 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:494B587CF0F85997 crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:rmpyOWgiP8SZMWZJNLvCQQeWEYw559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:9YsistBTbcjNfCyVReojJhAFNzM false sufficient binding region:162-231|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12241 uniprotkb:P27801 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-13130|uniprotkb:D6VYE3|ensemblfungi:YLR148W psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:pep3_yeast(display_long)|uniprotkb:VAM8(gene name synonym)|uniprotkb:VPS18(gene name synonym)|uniprotkb:VPT18(gene name synonym)|uniprotkb:L9634.2(orf name)|uniprotkb:YLR148W(locus name)|uniprotkb:PEP3(gene name)|psi-mi:PEP3(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 18(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 8(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 18(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016686|imex:IM-23338-10|dip:DIP-197287E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_013249.1|sgd:S000004138|mint:P27801|dip:DIP-5912N|ensemblfungi:YLR148W(gene)|ensemblfungi:YLR148W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048284"(organelle fusion)|go:"GO:0099022"(vesicle tethering)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR007810(Pep3/Vps18/deep orange)|rcsb pdb:4UUY psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:37AE3C34AE0470B8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:AVu+SV1ZyurPbskFNoxIyGlo0n0559292 rigid:xmU/z7ejMVwTIMF8mIlnHchlP0Q false sufficient binding region:182-264|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12241 uniprotkb:P20795 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016686|imex:IM-23338-10|dip:DIP-197287E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:xmU/z7ejMVwTIMF8mIlnHchlP0Q false sufficient binding region:182-264|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12241 uniprotkb:Q12255 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-35465|uniprotkb:D6VY93|ensemblfungi:YLR093C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:nyv1_yeast(display_long)|uniprotkb:NYV1(gene name)|psi-mi:NYV1(display_short)|uniprotkb:Synaptobrevin NYV1(gene name synonym)|uniprotkb:New v-SNARE 1(gene name synonym)|uniprotkb:MAM2(gene name synonym)|uniprotkb:YLR093C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016656|imex:IM-23338-9|dip:DIP-197291E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_013194.2|sgd:S000004083|mint:Q12255|dip:DIP-2248N|ensemblfungi:YLR093C(gene)|ensemblfungi:YLR093C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031201"(SNARE complex)|go:"GO:0042144"(vacuole fusion, non-autophagic)|interpro:IPR001388(Synaptobrevin)|interpro:IPR019005|interpro:IPR038426|interpro:IPR042855|rcsb pdb:2FZ0|reactome:R-SCE-199992 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:494B587CF0F85997 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:rmpyOWgiP8SZMWZJNLvCQQeWEYw559292 rigid:9WZagT8xWI1IVsJBCEmYPA5z7H0 false sufficient binding region:182-264|glutathione s tranferase tag:c-c sufficient binding region:1-231 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12241 uniprotkb:P32912 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20232|uniprotkb:D6VTU3|ensemblfungi:YGL212W psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vam7_yeast(display_long)|uniprotkb:VAM7(gene name)|psi-mi:VAM7(display_short)|uniprotkb:YGL212W(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016656|imex:IM-23338-9|dip:DIP-197291E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_011303.1|sgd:S000003180|ensemblfungi:YGL212W(gene)|ensemblfungi:YGL212W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0061909"(autophagosome-lysosome fusion)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001683(Phox-like)|interpro:IPR036871|rcsb pdb:1KMD|dip:DIP-1722N|mint:P32912 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:2F992AEC0ACBC8FE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:RC40scMhwxxJHE4gke72JgkKeh4559292 rigid:9WZagT8xWI1IVsJBCEmYPA5z7H0 false sufficient binding region:182-264|glutathione s tranferase tag:c-c sufficient binding region:190-316 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12241 uniprotkb:Q04338 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016656|imex:IM-23338-9|dip:DIP-197291E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:E55B4DA3B40FAD67 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rigid:9WZagT8xWI1IVsJBCEmYPA5z7H0 false sufficient binding region:182-264|glutathione s tranferase tag:c-c sufficient binding region:1-194 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12241 uniprotkb:P20795 intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-16016656|imex:IM-23338-9|dip:DIP-197291E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 psi-mi:"MI:0465"(dip) crc64:6415D9D852C6C64D crc64:ED78DF55109C20E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rigid:9WZagT8xWI1IVsJBCEmYPA5z7H0 false sufficient binding region:182-264|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P20795 uniprotkb:Q12241 intact:EBI-20395|uniprotkb:D6VZ31|ensemblfungi:YLR396C intact:EBI-20227|uniprotkb:D6W2G5|ensemblfungi:YOR106W psi-mi:vps33_yeast(display_long)|uniprotkb:VPS33(gene name)|psi-mi:VPS33(display_short)|uniprotkb:SLP1(gene name synonym)|uniprotkb:Protein SLP1(gene name synonym)|uniprotkb:Vacuolar morphogenesis protein 5(gene name synonym)|uniprotkb:VAM5(gene name synonym)|uniprotkb:L8084.15(orf name)|uniprotkb:YLR396C(locus name) psi-mi:vam3_yeast(display_long)|uniprotkb:VAM3(gene name)|psi-mi:VAM3(display_short)|uniprotkb:PTH1(gene name synonym)|uniprotkb:YOR106W(locus name)|uniprotkb:YOR3220W(orf name)|uniprotkb:Vacuolar morphogenesis protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Lobingier et al. (2012) pubmed:23051737|doi:10.1091/mbc.e12-05-0343|imex:IM-23338 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016750|imex:IM-23338-13|dip:DIP-10570E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004388|refseq:NP_013500.3|ensemblfungi:YLR396C(gene)|ensemblfungi:YLR396C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007033"(vacuole organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0099022"(vesicle tethering)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043155|go:"GO:0030897"(HOPS complex)|go:"GO:0033263"(CORVET complex)|dip:DIP-5910N|mint:P20795 refseq:NP_014749.1|sgd:S000005632|ensemblfungi:YOR106W(gene)|ensemblfungi:YOR106W_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0048278"(vesicle docking)|go:"GO:0051469"(vesicle fusion with vacuole)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:1HS7|reactome:R-SCE-204005|dip:DIP-1726N|mint:Q12241 psi-mi:"MI:0465"(dip) crc64:ED78DF55109C20E7 crc64:6415D9D852C6C64D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:dvU4L6IiTp4TrzhQXye070fL6q0559292 rogid:MgFv5I1ti3TNdnnlKL6cCak8lEw559292 rigid:gv8jqCaAL2AdoIqI+ATskW76TxA false - sufficient binding region:199-264|glutathione s tranferase tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)