#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A6A8 uniprotkb:P13001 intact:EBI-542566|uniprotkb:P02901|uniprotkb:Q53352|ensemblbacteria:AAC74178|ensemblbacteria:BAA35902 intact:EBI-1132260|uniprotkb:Q2M777|ensemblbacteria:AAC76437|ensemblbacteria:BAE77879 psi-mi:acp_ecoli(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:b1094(locus name)|uniprotkb:JW1080(locus name)|uniprotkb:Cytosolic-activating factor(gene name synonym)|uniprotkb:Fatty acid synthase acyl carrier protein(gene name synonym) psi-mi:bioh_ecoli(display_long)|uniprotkb:Biotin synthesis protein BioH(gene name synonym)|uniprotkb:bioH(gene name)|psi-mi:bioH(display_short)|uniprotkb:bioB(gene name synonym)|uniprotkb:b3412(locus name)|uniprotkb:JW3375(locus name)|uniprotkb:Carboxylesterase BioH(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Agarwal et al. (2012) pubmed:23045647|doi:10.1073/pnas.1207028109|imex:IM-21287 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016264|imex:IM-21287-1|dip:DIP-191247E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAA35902(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009245"(lipid A biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042493"|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|rcsb pdb:1ACP|rcsb pdb:1L0H|rcsb pdb:1L0I|rcsb pdb:1T8K|rcsb pdb:2FAC|rcsb pdb:2FAD|rcsb pdb:2FAE|rcsb pdb:2FHS|rcsb pdb:2K92|rcsb pdb:2K93|rcsb pdb:2K94|rcsb pdb:3EJB|rcsb pdb:3EJD|rcsb pdb:3EJE|rcsb pdb:3NY7|rcsb pdb:5KOF|rcsb pdb:5USR|rcsb pdb:5VCB|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:6DFL|rcsb pdb:6N3P|rcsb pdb:6OKC|rcsb pdb:6OKF|rcsb pdb:6OKG|rcsb pdb:6OLT|rcsb pdb:6U0J|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6W98|rcsb pdb:6WI2|rcsb pdb:6WIH|ensemblbacteria:AAC74178(transcript)|ensemblbacteria:b1094(gene)|ensemblbacteria:BAA35902(gene)|refseq:NP_415612.1|refseq:WP_000103754.1|dip:DIP-29374N refseq:WP_001060070.1|refseq:NP_417871.1|ensemblbacteria:AAC76437(transcript)|ensemblbacteria:b3412(gene)|ensemblbacteria:BAE77879(gene)|ensemblbacteria:BAE77879(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0090499"(pimelyl-[acyl-carrier protein] methyl ester esterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR010076(BioH)|interpro:IPR029058|rcsb pdb:1M33|dip:DIP-9223N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:w6swP4kUNVbMszx95i4+fmxoFi483333 rogid:JHQsNVg48KpVIhDY7Zzeirxy9fg83333 rigid:VN2rjel6eL0xrk5X6CIz6tYp/4s false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A6A8 uniprotkb:P13001 intact:EBI-542566|uniprotkb:P02901|uniprotkb:Q53352|ensemblbacteria:AAC74178|ensemblbacteria:BAA35902 intact:EBI-1132260|uniprotkb:Q2M777|ensemblbacteria:AAC76437|ensemblbacteria:BAE77879 psi-mi:acp_ecoli(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:b1094(locus name)|uniprotkb:JW1080(locus name)|uniprotkb:Cytosolic-activating factor(gene name synonym)|uniprotkb:Fatty acid synthase acyl carrier protein(gene name synonym) psi-mi:bioh_ecoli(display_long)|uniprotkb:Biotin synthesis protein BioH(gene name synonym)|uniprotkb:bioH(gene name)|psi-mi:bioH(display_short)|uniprotkb:bioB(gene name synonym)|uniprotkb:b3412(locus name)|uniprotkb:JW3375(locus name)|uniprotkb:Carboxylesterase BioH(gene name synonym) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Agarwal et al. (2012) pubmed:23045647|doi:10.1073/pnas.1207028109|imex:IM-21287 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016281|imex:IM-21287-2|dip:DIP-191247E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAA35902(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009245"(lipid A biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042493"|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|rcsb pdb:1ACP|rcsb pdb:1L0H|rcsb pdb:1L0I|rcsb pdb:1T8K|rcsb pdb:2FAC|rcsb pdb:2FAD|rcsb pdb:2FAE|rcsb pdb:2FHS|rcsb pdb:2K92|rcsb pdb:2K93|rcsb pdb:2K94|rcsb pdb:3EJB|rcsb pdb:3EJD|rcsb pdb:3EJE|rcsb pdb:3NY7|rcsb pdb:5KOF|rcsb pdb:5USR|rcsb pdb:5VCB|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:6DFL|rcsb pdb:6N3P|rcsb pdb:6OKC|rcsb pdb:6OKF|rcsb pdb:6OKG|rcsb pdb:6OLT|rcsb pdb:6U0J|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6W98|rcsb pdb:6WI2|rcsb pdb:6WIH|ensemblbacteria:AAC74178(transcript)|ensemblbacteria:b1094(gene)|ensemblbacteria:BAA35902(gene)|refseq:NP_415612.1|refseq:WP_000103754.1|dip:DIP-29374N refseq:WP_001060070.1|refseq:NP_417871.1|ensemblbacteria:AAC76437(transcript)|ensemblbacteria:b3412(gene)|ensemblbacteria:BAE77879(gene)|ensemblbacteria:BAE77879(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0090499"(pimelyl-[acyl-carrier protein] methyl ester esterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR010076(BioH)|interpro:IPR029058|rcsb pdb:1M33|dip:DIP-9223N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:w6swP4kUNVbMszx95i4+fmxoFi483333 rogid:JHQsNVg48KpVIhDY7Zzeirxy9fg83333 rigid:VN2rjel6eL0xrk5X6CIz6tYp/4s false - mutation:82-82 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A6A8 uniprotkb:P13001 intact:EBI-542566|uniprotkb:P02901|uniprotkb:Q53352|ensemblbacteria:AAC74178|ensemblbacteria:BAA35902 intact:EBI-1132260|uniprotkb:Q2M777|ensemblbacteria:AAC76437|ensemblbacteria:BAE77879 psi-mi:acp_ecoli(display_long)|uniprotkb:acpP(gene name)|psi-mi:acpP(display_short)|uniprotkb:b1094(locus name)|uniprotkb:JW1080(locus name)|uniprotkb:Cytosolic-activating factor(gene name synonym)|uniprotkb:Fatty acid synthase acyl carrier protein(gene name synonym) psi-mi:bioh_ecoli(display_long)|uniprotkb:Biotin synthesis protein BioH(gene name synonym)|uniprotkb:bioH(gene name)|psi-mi:bioH(display_short)|uniprotkb:bioB(gene name synonym)|uniprotkb:b3412(locus name)|uniprotkb:JW3375(locus name)|uniprotkb:Carboxylesterase BioH(gene name synonym) psi-mi:"MI:0415"(enzymatic study) Agarwal et al. (2012) pubmed:23045647|doi:10.1073/pnas.1207028109|imex:IM-21287 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0414"(enzymatic reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16016301|imex:IM-21287-3|dip:DIP-191247E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAA35902(transcript)|go:"GO:0000035"(acyl binding)|go:"GO:0000036"(acyl carrier activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009245"(lipid A biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042493"|interpro:IPR003231("Acyl carrier protein (ACP)")|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR036736|rcsb pdb:1ACP|rcsb pdb:1L0H|rcsb pdb:1L0I|rcsb pdb:1T8K|rcsb pdb:2FAC|rcsb pdb:2FAD|rcsb pdb:2FAE|rcsb pdb:2FHS|rcsb pdb:2K92|rcsb pdb:2K93|rcsb pdb:2K94|rcsb pdb:3EJB|rcsb pdb:3EJD|rcsb pdb:3EJE|rcsb pdb:3NY7|rcsb pdb:5KOF|rcsb pdb:5USR|rcsb pdb:5VCB|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:6DFL|rcsb pdb:6N3P|rcsb pdb:6OKC|rcsb pdb:6OKF|rcsb pdb:6OKG|rcsb pdb:6OLT|rcsb pdb:6U0J|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6W98|rcsb pdb:6WI2|rcsb pdb:6WIH|ensemblbacteria:AAC74178(transcript)|ensemblbacteria:b1094(gene)|ensemblbacteria:BAA35902(gene)|refseq:NP_415612.1|refseq:WP_000103754.1|dip:DIP-29374N refseq:WP_001060070.1|refseq:NP_417871.1|ensemblbacteria:AAC76437(transcript)|ensemblbacteria:b3412(gene)|ensemblbacteria:BAE77879(gene)|ensemblbacteria:BAE77879(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009102"(biotin biosynthetic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0090499"(pimelyl-[acyl-carrier protein] methyl ester esterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR010076(BioH)|interpro:IPR029058|rcsb pdb:1M33|dip:DIP-9223N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:w6swP4kUNVbMszx95i4+fmxoFi483333 rogid:JHQsNVg48KpVIhDY7Zzeirxy9fg83333 rigid:VN2rjel6eL0xrk5X6CIz6tYp/4s false - mutation disrupting interaction rate:82-82|mutation disrupting interaction rate:155-155,142-142,138-138|mutation disrupting interaction rate:159-159,142-142,138-138|mutation disrupting interaction rate:159-159,155-155,142-142,138-138|mutation disrupting interaction rate:159-159,155-155,142-142|mutation decreasing interaction rate:159-159,155-155,138-138 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)