#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17612 uniprotkb:Q8AXF4 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-16014754|imex:IM-25195-1|dip:DIP-200692E - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N psi-mi:"MI:0465"(dip) - comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rigid:sOq65EFPAyDwIu7Ktl3ECOz9A+s false - mutation disrupting interaction rate:344-344,342-342,336-336,335-335 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8AXF4 uniprotkb:Q6GQ04 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-995003 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q6gq04_xenla(display_long)|uniprotkb:cdc27.S(gene name)|psi-mi:cdc27.S(display_short)|uniprotkb:MGC80529(gene name synonym)|uniprotkb:cdc27(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16014777|imex:IM-25195-2|dip:DIP-200688E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_001085568.1|dip:DIP-61882N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2017/08/07 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:4kDiMS+d9DpEZyPbzDsa/pzmFB48355 rigid:2cZ0XtikPETG1bQuAe1FWc9LQe4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8AXF4 uniprotkb:Q5XH34 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-16014794 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q5xh34_xenla(display_long)|uniprotkb:ppp2r5e.S(gene name)|psi-mi:ppp2r5e.S(display_short)|uniprotkb:LOC495076(gene name synonym)|uniprotkb:ppp2r5e(gene name synonym)|uniprotkb:XELAEV_18041141mg(orf name) psi-mi:"MI:0096"(pull down) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16014809|imex:IM-25195-3|dip:DIP-200689E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001088245.1|dip:DIP-61885N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:JeHR5lGLHFfY3/BaKjceT//rELU8355 rigid:vvmMTF1yekm//u07qmSAtUOQhI0 false sufficient binding region:301-400|mutation disrupting interaction strength:344-344,342-342,336-336,335-335|glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8AXF4 uniprotkb:Q6GQ04 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-995003 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q6gq04_xenla(display_long)|uniprotkb:cdc27.S(gene name)|psi-mi:cdc27.S(display_short)|uniprotkb:MGC80529(gene name synonym)|uniprotkb:cdc27(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16014838|imex:IM-25195-4|dip:DIP-200688E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|refseq:NP_001085568.1|dip:DIP-61882N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2017/08/07 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:4kDiMS+d9DpEZyPbzDsa/pzmFB48355 rigid:2cZ0XtikPETG1bQuAe1FWc9LQe4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8AXF4 uniprotkb:Q6DFL3 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-16014855 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q6dfl3_xenla(display_long)|uniprotkb:ppp2r5b.L(gene name)|psi-mi:ppp2r5b.L(display_short)|uniprotkb:ppp2r5b(gene name synonym)|uniprotkb:ppp2r5e-prov(gene name synonym)|uniprotkb:XELAEV_18026204mg(orf name) psi-mi:"MI:0096"(pull down) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16014870|imex:IM-25195-5|dip:DIP-200691E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001086500.1|dip:DIP-61884N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:3Kq/NpC+B6YGZPLUtHC/Yn39ejk8355 rigid:8SluB6pWTx4oV0yNRggPD1NvL7Q false sufficient binding region:301-400|mutation disrupting interaction strength:344-344,342-342,336-336,335-335|glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8AXF4 uniprotkb:Q5XH34 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-16014794 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:q5xh34_xenla(display_long)|uniprotkb:ppp2r5e.S(gene name)|psi-mi:ppp2r5e.S(display_short)|uniprotkb:LOC495076(gene name synonym)|uniprotkb:ppp2r5e(gene name synonym)|uniprotkb:XELAEV_18041141mg(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16014899|imex:IM-25195-6|dip:DIP-200689E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001088245.1|dip:DIP-61885N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") - 2017/08/07 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:JeHR5lGLHFfY3/BaKjceT//rELU8355 rigid:vvmMTF1yekm//u07qmSAtUOQhI0 false - flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8AXF4 uniprotkb:A9YWT2 intact:EBI-8609042|uniprotkb:Q9PTL8|intact:MINT-8176781 intact:EBI-16014918 psi-mi:fbx43_xenla(display_long)|uniprotkb:fbxo43(gene name)|psi-mi:fbxo43(display_short)|uniprotkb:emi2(gene name synonym)|uniprotkb:erp1(gene name synonym)|uniprotkb:fbx26(gene name synonym)|uniprotkb:Early mitotic inhibitor 2(gene name synonym)|uniprotkb:Emi1-related protein 1(gene name synonym)|uniprotkb:F-box protein 26(gene name synonym)|uniprotkb:Xerp1(gene name synonym) psi-mi:a9ywt2_xenla(display_long)|uniprotkb:ppp2r5a.S(gene name)|psi-mi:ppp2r5a.S(display_short)|uniprotkb:ppp2r5a(gene name synonym)|uniprotkb:XELAEV_18028697mg(orf name) psi-mi:"MI:0096"(pull down) Tischer et al. (2012) pubmed:23019610|doi:10.1126/science.1228394|imex:IM-25195 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16014932|imex:IM-25195-7|dip:DIP-200690E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR044064|refseq:NP_001093338.1|refseq:XP_018121628.1|dip:DIP-46217N go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001108316.1|dip:DIP-61883N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:/ZtkR0XR14Vbd25kJFWs1OHIfwQ8355 rogid:JrbHqiruoC5TPWBbVpEjIvUlZg88355 rigid:FX8tptcELh7tGoDk9Jz28HSw3Ic false sufficient binding region:301-400|mutation disrupting interaction strength:344-344,342-342,336-336,335-335|glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)