#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O97143	uniprotkb:O97143	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013766|imex:IM-18597-2|dip:DIP-190052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:yf3vxL4FBHd9SHB4v6h+pvw7K/0	false	sufficient binding region:382-602	sufficient binding region:382-602	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O97143	uniprotkb:O97143	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013748|imex:IM-18597-1|dip:DIP-190052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:yf3vxL4FBHd9SHB4v6h+pvw7K/0	false	sufficient binding region:382-602	sufficient binding region:382-602	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O97143	uniprotkb:O97143	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013784|imex:IM-18597-3|dip:DIP-190052E	-	-	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/07	2017/08/10	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:yf3vxL4FBHd9SHB4v6h+pvw7K/0	false	sufficient binding region:1-317	sufficient binding region:1-317	-	0	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O97143	uniprotkb:O97143	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0104"(static light scattering)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013802|imex:IM-18597-4|dip:DIP-190052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:yf3vxL4FBHd9SHB4v6h+pvw7K/0	false	sufficient binding region:382-602	sufficient binding region:382-602	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O97143	uniprotkb:O97143	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013820|imex:IM-18597-5|dip:DIP-190052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:kyWLp19tHF5kLN6IkOKbgjMeReI	false	myc tag:c-c	green fluorescent protein tag:c-c|sufficient binding region:382-602	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O97143	uniprotkb:O97143	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013872|imex:IM-18597-7|dip:DIP-190052E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/07	2017/08/10	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:yf3vxL4FBHd9SHB4v6h+pvw7K/0	false	sufficient binding region:382-602	sufficient binding region:382-602	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9VNE4	uniprotkb:O97143	intact:EBI-108604|uniprotkb:Q7YTY4|ensemblmetazoa:FBpp0078392	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:q9vne4_drome(display_long)|uniprotkb:DmAsl(gene name synonym)|uniprotkb:asl(gene name)|psi-mi:asl(display_short)|uniprotkb:CG2919(orf name)|uniprotkb:ASL(gene name synonym)|uniprotkb:Asl(gene name synonym)|uniprotkb:Dmel\CG2919(gene name synonym)|uniprotkb:mecD(gene name synonym)|uniprotkb:sdu(gene name synonym)|uniprotkb:Dmel_CG2919(orf name)|uniprotkb:Cep152(gene name synonym)|uniprotkb:MecD(gene name synonym)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013843|imex:IM-18597-6|dip:DIP-188230E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_649557.2|flybase:FBgn0261004|dip:DIP-59503N|ensemblmetazoa:FBgn0261004(gene)|ensemblmetazoa:FBtr0078743(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007338"(single fertilization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0036064"(ciliary basal body)|go:"GO:1903723"(negative regulation of centriole elongation)|go:"GO:1905515"(non-motile cilium assembly)	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:6PZMMJBBhXtp8MaXHx9klNTsnig7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:5dVig8qkRcvsqdw4fxmsKsiWovA	false	sufficient binding region:1-300|v5 tag:c-c	sufficient binding region:382-602|mutation increasing interaction strength:297-297,293-293|green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9VDE3	uniprotkb:O97143	intact:EBI-91763|ensemblmetazoa:FBpp0083434|ensemblmetazoa:FBpp0306059	intact:EBI-162366|uniprotkb:Q86NL8|ensemblmetazoa:FBpp0078042	psi-mi:q9vde3_drome(display_long)|uniprotkb:slmb(gene name)|psi-mi:slmb(display_short)|uniprotkb:beta-TrCP(gene name synonym)|uniprotkb:"BcDNA:GM02031"(gene name synonym)|uniprotkb:Beta-TRCP1(gene name synonym)|uniprotkb:Dmel\CG3412(gene name synonym)|uniprotkb:FBXW1(gene name synonym)|uniprotkb:"MENE (3R)-B"(gene name synonym)|uniprotkb:"MENE(3R)-B"(gene name synonym)|uniprotkb:SLIMB(gene name synonym)|uniprotkb:SLMB(gene name synonym)|uniprotkb:Slimb(gene name synonym)|uniprotkb:Slmb(gene name synonym)|uniprotkb:beta-TRCP(gene name synonym)|uniprotkb:betaTrCP(gene name synonym)|uniprotkb:crd(gene name synonym)|uniprotkb:ica(gene name synonym)|uniprotkb:"l(3)00295"(gene name synonym)|uniprotkb:shv(gene name synonym)|uniprotkb:slimb(gene name synonym)|uniprotkb:wel(gene name synonym)|uniprotkb:Dmel_CG3412(orf name)|uniprotkb:CG3412(orf name)	psi-mi:plk4_drome(display_long)|uniprotkb:SAK(gene name)|psi-mi:SAK(display_short)|uniprotkb:CG7186(orf name)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SAK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Slevin et al. (2012)	pubmed:23000383|doi:10.1016/j.str.2012.08.025|imex:IM-18597	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013890|imex:IM-18597-8|dip:DIP-189049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0283468|refseq:NP_524430.1|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045849"(negative regulation of nurse cell apoptotic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903688"(positive regulation of border follicle cell migration)|go:"GO:2000114"(regulation of establishment of cell polarity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|ensemblmetazoa:FBgn0283468(gene)|ensemblmetazoa:FBtr0084032(transcript)|ensemblmetazoa:FBtr0333931(transcript)|go:"GO:0006508"(proteolysis)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0007309"(oocyte axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030708"(germarium-derived female germ-line cyst encapsulation)|go:"GO:0030713"(ovarian follicle cell stalk formation)|go:"GO:0030720"(oocyte localization involved in germarium-derived egg chamber formation)|go:"GO:0030727"(germarium-derived female germ-line cyst formation)|refseq:NP_001262801.1|dip:DIP-22524N	refseq:NP_649324.1|flybase:FBgn0026371|ensemblmetazoa:FBgn0026371(gene)|ensemblmetazoa:FBtr0078387(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|rcsb pdb:4G7N|rcsb pdb:4NK7|rcsb pdb:5LHX|dip:DIP-49071N	psi-mi:"MI:0465"(dip)	-	-	comment:Deletion of region 382-602 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/07	2017/08/10	rogid:4WM8B/xRk+ezxr9VCBG/jw6fwYw7227	rogid:79lsmHI1AKypIeTYWs23Z5ICJpA7227	rigid:gmt9OkWi5hIJiBc4v6Fa+iSHlnw	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)