#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P19493	uniprotkb:P19493	intact:EBI-7761834|uniprotkb:Q64241|intact:MINT-86166	intact:EBI-7761834|uniprotkb:Q64241|intact:MINT-86166	psi-mi:gria4_rat(display_long)|uniprotkb:Gria4(gene name)|psi-mi:Gria4(display_short)|uniprotkb:Glur4(gene name synonym)|uniprotkb:GluR-D(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 4(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 4(gene name synonym)	psi-mi:gria4_rat(display_long)|uniprotkb:Gria4(gene name)|psi-mi:Gria4(display_short)|uniprotkb:Glur4(gene name synonym)|uniprotkb:GluR-D(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 4(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 4(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Dutta et al. (2012)	pubmed:22959625|doi:10.1016/j.str.2012.08.012|imex:IM-18593	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16013244|imex:IM-18593-1|dip:DIP-190049E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045202"(synapse)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|mint:P19493|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3EN3|rcsb pdb:3EPE|rcsb pdb:3FAS|rcsb pdb:3FAT|rcsb pdb:3KEI|rcsb pdb:3KFM|go:"GO:0050803"(regulation of synapse structure or activity)|rcsb pdb:5FWX|reactome:R-RNO-399710|reactome:R-RNO-399719|reactome:R-RNO-416993|reactome:R-RNO-438066|reactome:R-RNO-8849932|rcsb pdb:4GPA|refseq:NP_058959.2|rgd:61863|refseq:NP_001106655.1|dip:DIP-41142N	go:"GO:0045202"(synapse)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|mint:P19493|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3EN3|rcsb pdb:3EPE|rcsb pdb:3FAS|rcsb pdb:3FAT|rcsb pdb:3KEI|rcsb pdb:3KFM|go:"GO:0050803"(regulation of synapse structure or activity)|rcsb pdb:5FWX|reactome:R-RNO-399710|reactome:R-RNO-399719|reactome:R-RNO-416993|reactome:R-RNO-438066|reactome:R-RNO-8849932|rcsb pdb:4GPA|refseq:NP_058959.2|rgd:61863|refseq:NP_001106655.1|dip:DIP-41142N	psi-mi:"MI:0465"(dip)	comment:mint|function:Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist|comment:homomint	comment:mint|function:Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist|comment:homomint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/07	2017/08/10	rogid:QjQ372QPW7bhK1b5oDC7/C0HkxA10116	rogid:QjQ372QPW7bhK1b5oDC7/C0HkxA10116	rigid:f+t7ACJQBrH6RVrL4fX+/KfIdl0	false	sufficient binding region:22-401	sufficient binding region:22-401	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)