#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96CB9-1 uniprotkb:Q7Z6M4 intact:EBI-16012886|ensembl:ENSP00000419740 intact:EBI-948435|ensembl:ENSP00000241527|ensembl:ENSP00000375840|ensembl:ENSP00000480378|uniprotkb:Q9P0E0|uniprotkb:A8K6K0 psi-mi:q96cb9-1(display_long)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:mtef4_human(display_long)|uniprotkb:Mitochondrial transcription termination factor 4(gene name synonym)|uniprotkb:mTERF domain-containing protein 2(gene name synonym)|uniprotkb:MTERF4(gene name)|psi-mi:MTERF4(display_short)|uniprotkb:MTERFD2(gene name synonym)|uniprotkb:HSPC096(orf name) psi-mi:"MI:0096"(pull down) Spåhr et al. (2012) pubmed:22949673|doi:10.1073/pnas.1210688109|imex:IM-20712 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16012893|imex:IM-20712-1|dip:DIP-190053E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|intact:EBI-744435(isoform-parent) go:"GO:0007507"(heart development)|go:"GO:0019843"(rRNA binding)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043010"(camera-type eye development)|interpro:IPR003690(Mitochodrial transcription termination factor-related)|interpro:IPR038538|rcsb pdb:4FP9|rcsb pdb:4FZV|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-6793080|go:"GO:0006364"(rRNA processing)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006626"(protein targeting to mitochondrion)|ensembl:ENSG00000122085(gene)|ensembl:ENST00000241527(transcript)|ensembl:ENST00000391980(transcript)|ensembl:ENST00000614476(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_872307.2|refseq:XP_016858876.1|dip:DIP-49918N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rogid:hEwxLvLP6detYNELl7LYEVnThKA9606 rigid:3NBylstnMEXR/3au6i/AWa5GJZA false sufficient binding region:26-384 sufficient binding region:48-381|his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CB9-1 uniprotkb:Q7Z6M4 intact:EBI-16012886|ensembl:ENSP00000419740 intact:EBI-948435|ensembl:ENSP00000241527|ensembl:ENSP00000375840|ensembl:ENSP00000480378|uniprotkb:Q9P0E0|uniprotkb:A8K6K0 psi-mi:q96cb9-1(display_long)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:mtef4_human(display_long)|uniprotkb:Mitochondrial transcription termination factor 4(gene name synonym)|uniprotkb:mTERF domain-containing protein 2(gene name synonym)|uniprotkb:MTERF4(gene name)|psi-mi:MTERF4(display_short)|uniprotkb:MTERFD2(gene name synonym)|uniprotkb:HSPC096(orf name) psi-mi:"MI:0114"(x-ray crystallography) Spåhr et al. (2012) pubmed:22949673|doi:10.1073/pnas.1210688109|imex:IM-20712 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16012941|imex:IM-20712-3|dip:DIP-190053E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|intact:EBI-744435(isoform-parent) go:"GO:0007507"(heart development)|go:"GO:0019843"(rRNA binding)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043010"(camera-type eye development)|interpro:IPR003690(Mitochodrial transcription termination factor-related)|interpro:IPR038538|rcsb pdb:4FP9|rcsb pdb:4FZV|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-6793080|go:"GO:0006364"(rRNA processing)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006626"(protein targeting to mitochondrion)|ensembl:ENSG00000122085(gene)|ensembl:ENST00000241527(transcript)|ensembl:ENST00000391980(transcript)|ensembl:ENST00000614476(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_872307.2|refseq:XP_016858876.1|dip:DIP-49918N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rogid:hEwxLvLP6detYNELl7LYEVnThKA9606 rigid:3NBylstnMEXR/3au6i/AWa5GJZA false sufficient binding region:26-384 sufficient binding region:48-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CB9-1 uniprotkb:Q7Z6M4 intact:EBI-16012886|ensembl:ENSP00000419740 intact:EBI-948435|ensembl:ENSP00000241527|ensembl:ENSP00000375840|ensembl:ENSP00000480378|uniprotkb:Q9P0E0|uniprotkb:A8K6K0 psi-mi:q96cb9-1(display_long)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:mtef4_human(display_long)|uniprotkb:Mitochondrial transcription termination factor 4(gene name synonym)|uniprotkb:mTERF domain-containing protein 2(gene name synonym)|uniprotkb:MTERF4(gene name)|psi-mi:MTERF4(display_short)|uniprotkb:MTERFD2(gene name synonym)|uniprotkb:HSPC096(orf name) psi-mi:"MI:0071"(molecular sieving) Spåhr et al. (2012) pubmed:22949673|doi:10.1073/pnas.1210688109|imex:IM-20712 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16012962|imex:IM-20712-4|dip:DIP-190053E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|intact:EBI-744435(isoform-parent) go:"GO:0007507"(heart development)|go:"GO:0019843"(rRNA binding)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043010"(camera-type eye development)|interpro:IPR003690(Mitochodrial transcription termination factor-related)|interpro:IPR038538|rcsb pdb:4FP9|rcsb pdb:4FZV|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-6793080|go:"GO:0006364"(rRNA processing)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006626"(protein targeting to mitochondrion)|ensembl:ENSG00000122085(gene)|ensembl:ENST00000241527(transcript)|ensembl:ENST00000391980(transcript)|ensembl:ENST00000614476(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_872307.2|refseq:XP_016858876.1|dip:DIP-49918N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rogid:hEwxLvLP6detYNELl7LYEVnThKA9606 rigid:3NBylstnMEXR/3au6i/AWa5GJZA false sufficient binding region:26-384 sufficient binding region:48-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CB9-1 uniprotkb:Q96CB9-1 intact:EBI-16012886|ensembl:ENSP00000419740 intact:EBI-16012886|ensembl:ENSP00000419740 psi-mi:q96cb9-1(display_long)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:q96cb9-1(display_long)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Spåhr et al. (2012) pubmed:22949673|doi:10.1073/pnas.1210688109|imex:IM-20712 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16012916|imex:IM-20712-2|dip:DIP-190364E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|intact:EBI-744435(isoform-parent) ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|intact:EBI-744435(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/07 2017/08/10 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rigid:FsNRnge4Ije5K+Hgb35GLmmDWUQ false sufficient binding region:26-384|mutation:65-65,141-141,139-139,136-136 sufficient binding region:26-384|mutation:65-65,141-141,139-139,136-136 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CB9-1 uniprotkb:Q7Z6M4 intact:EBI-16012886|ensembl:ENSP00000419740 intact:EBI-948435|ensembl:ENSP00000241527|ensembl:ENSP00000375840|ensembl:ENSP00000480378|uniprotkb:Q9P0E0|uniprotkb:A8K6K0 psi-mi:q96cb9-1(display_long)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:mtef4_human(display_long)|uniprotkb:Mitochondrial transcription termination factor 4(gene name synonym)|uniprotkb:mTERF domain-containing protein 2(gene name synonym)|uniprotkb:MTERF4(gene name)|psi-mi:MTERF4(display_short)|uniprotkb:MTERFD2(gene name synonym)|uniprotkb:HSPC096(orf name) psi-mi:"MI:0071"(molecular sieving) Spåhr et al. (2012) pubmed:22949673|doi:10.1073/pnas.1210688109|imex:IM-20712 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16012983|imex:IM-20712-5|dip:DIP-190053E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|intact:EBI-744435(isoform-parent) go:"GO:0007507"(heart development)|go:"GO:0019843"(rRNA binding)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043010"(camera-type eye development)|interpro:IPR003690(Mitochodrial transcription termination factor-related)|interpro:IPR038538|rcsb pdb:4FP9|rcsb pdb:4FZV|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-6793080|go:"GO:0006364"(rRNA processing)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006626"(protein targeting to mitochondrion)|ensembl:ENSG00000122085(gene)|ensembl:ENST00000241527(transcript)|ensembl:ENST00000391980(transcript)|ensembl:ENST00000614476(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_872307.2|refseq:XP_016858876.1|dip:DIP-49918N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/07 2017/08/10 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rogid:hEwxLvLP6detYNELl7LYEVnThKA9606 rigid:3NBylstnMEXR/3au6i/AWa5GJZA false sufficient binding region:26-384|mutation disrupting interaction strength:65-65,141-141,139-139,136-136 sufficient binding region:48-381 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)