#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53549 uniprotkb:P40327 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13901|uniprotkb:D6VRY1|ensemblfungi:YDL007W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:prs4_yeast(display_long)|uniprotkb:RPT2(gene name)|psi-mi:RPT2(display_short)|uniprotkb:YHS4(gene name synonym)|uniprotkb:YTA5(gene name synonym)|uniprotkb:YDL007W(locus name)|uniprotkb:D2920(orf name)|uniprotkb:Tat-binding homolog 5(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_010277.1|sgd:S000002165|ensemblfungi:YDL007W(gene)|ensemblfungi:YDL007W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0034629"|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:4CR2|rcsb pdb:3JCP|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-532668|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P40327|dip:DIP-6282N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:EB735354C3A0EBD4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:nSy31Q+snoZMZrFmXscv8/HQYk0559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P33297 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13920|uniprotkb:D6W2H6|ensemblfungi:YOR117W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:prs6a_yeast(display_long)|uniprotkb:RPT5(gene name)|psi-mi:RPT5(display_short)|uniprotkb:YTA1(gene name synonym)|uniprotkb:YOR117W(locus name)|uniprotkb:O3258(orf name)|uniprotkb:YOR3258W(orf name)|uniprotkb:Tat-binding protein homolog 1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000005643|rcsb pdb:3WHL|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|rcsb pdb:3WHK|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|ensemblfungi:YOR117W(gene)|ensemblfungi:YOR117W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|refseq:NP_014760.3|mint:P33297|dip:DIP-1590N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:C215422033FCE830 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:jsQE3SjBA0ZZcysuLgFe/5M6pOc559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P33298 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13905|ensemblfungi:YDR394W|uniprotkb:D6VT28 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:prs6b_yeast(display_long)|uniprotkb:RPT3(gene name)|psi-mi:RPT3(display_short)|uniprotkb:YNT1(gene name synonym)|uniprotkb:YTA2(gene name synonym)|uniprotkb:YDR394W(locus name)|uniprotkb:D9509.14(orf name)|uniprotkb:Protein YNT1(gene name synonym)|uniprotkb:Tat-binding homolog 2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000002802|ensemblfungi:YDR394W(gene)|ensemblfungi:YDR394W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:NP_010682.3|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|rcsb pdb:2DZN|rcsb pdb:2DZO|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33298|dip:DIP-1587N|interpro:IPR003960(AAA ATPase, conserved site) psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:E12F0995A60732BD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:teaQwAlS0ruTNKbLkX7kP4lkn7o559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P33299 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13910|uniprotkb:D6VX51|ensemblfungi:YKL145W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:prs7_yeast(display_long)|uniprotkb:YKL145W(locus name)|uniprotkb:RPT1(gene name)|psi-mi:RPT1(display_short)|uniprotkb:CIM5(gene name synonym)|uniprotkb:YTA3(gene name synonym)|uniprotkb:Protein CIM5(gene name synonym)|uniprotkb:Tat-binding homolog 3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_012777.1|sgd:S000001628|ensemblfungi:YKL145W(gene)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|ensemblfungi:YKL145W_mRNA(transcript)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|go:"GO:0005524"(ATP binding)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|go:"GO:0005634"(nucleus)|rcsb pdb:3VLF|rcsb pdb:4A3V|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4JPO|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|rcsb pdb:5A5B|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:5MP9|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045732"(positive regulation of protein catabolic process)|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:6EF3|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|mint:P33299|dip:DIP-2883N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:8454BBC9D549EC5C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:8XXo53yZ1KevHObtYWABeFr0hWo559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:Q01939 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:9C59E92A0794F60F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P21243 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13975|uniprotkb:P15708|ensemblfungi:YGL011C|uniprotkb:D6VUC6 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa1_yeast(display_long)|uniprotkb:SCL1(gene name)|psi-mi:SCL1(display_short)|uniprotkb:PRC2(gene name synonym)|uniprotkb:PRS2(gene name synonym)|uniprotkb:YGL011C(locus name)|uniprotkb:Proteasome component C7-alpha(gene name synonym)|uniprotkb:Macropain subunit C7-alpha(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex C7(gene name synonym)|uniprotkb:Proteasome component Y8(gene name synonym)|uniprotkb:SCL1 suppressor protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000002979|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|ensemblfungi:YGL011C(gene)|ensemblfungi:YGL011C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y69|rcsb pdb:4Y8K|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y8L|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|refseq:NP_011504.3|mint:P21243|dip:DIP-2810N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:5B938C862BC8D7EB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:CIMZa9bvEUzZ4k7XGnaC4irMOpo559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P23639 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13959|ensemblfungi:YML092C|uniprotkb:D6W0J3 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa2_yeast(display_long)|uniprotkb:PRE8(gene name)|psi-mi:PRE8(display_short)|uniprotkb:PRS4(gene name synonym)|uniprotkb:YML092C(locus name)|uniprotkb:Proteasome component Y7(gene name synonym)|uniprotkb:Macropain subunit Y7(gene name synonym)|uniprotkb:Proteinase YSCE subunit 7(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y7(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:2ZCY|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3OEV|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4INU|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5CZ5|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5JHR|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QV4|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:5MPC|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6EF3|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWF|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HVY|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-983168|reactome:R-SCE-8948751|ensemblfungi:YML092C(gene)|ensemblfungi:YML092C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|refseq:NP_013618.1|sgd:S000004557|mint:P23639|dip:DIP-2822N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:12D7DFB1AA10E9FE full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:HiJr+UwwGu+wQImwgq3TiHYELx8559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P23638 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13967|ensemblfungi:YGR135W|uniprotkb:D6VUR7 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa3_yeast(display_long)|uniprotkb:PRE9(gene name)|psi-mi:PRE9(display_short)|uniprotkb:YGR135W(locus name)|uniprotkb:PRS5(gene name synonym)|uniprotkb:Proteasome component Y13(gene name synonym)|uniprotkb:Macropain subunit Y13(gene name synonym)|uniprotkb:Proteinase YSCE subunit 13(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit Y13(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000003367|ensemblfungi:YGR135W(gene)|ensemblfungi:YGR135W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0080129"(proteasome core complex assembly)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:3OKJ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NO1|rcsb pdb:4NNN|rcsb pdb:4NO6|rcsb pdb:4NNW|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|rcsb pdb:6J2Q|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QVL|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|reactome:R-SCE-983168|reactome:R-SCE-8948751|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4QZ2|rcsb pdb:4Y70|rcsb pdb:4Y8H|rcsb pdb:4Y74|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y75|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y8R|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:4YA3|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:3OEV|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5FGF|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L60|rcsb pdb:5L5Z|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|refseq:NP_011651.3|mint:P23638|dip:DIP-2823N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:B43BB05233A01A9E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:5F6HrO7MputR68OA/1SAdFfJa4g559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P40303 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13980|ensemblfungi:YOL038W|uniprotkb:D6W229 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa4_yeast(display_long)|uniprotkb:PRE6(gene name)|psi-mi:PRE6(display_short)|uniprotkb:YOL038W(locus name)|uniprotkb:Proteasome component PRE6(gene name synonym)|uniprotkb:Macropain subunit PRE6(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE6(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE6(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 ensemblfungi:YOL038W(gene)|ensemblfungi:YOL038W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4QZ0|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4Y8G|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXL|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FG7|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5L6C|rcsb pdb:6FVW|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6FVX|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6HWD|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4HNP|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QV0|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|refseq:NP_014604.1|sgd:S000005398|mint:P40303|dip:DIP-4844N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:73AEE63B836E618A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:G8IQr0G8FhiWc0DYUlh3vecHQsU559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P32379 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13971|ensemblfungi:YGR253C|uniprotkb:D6VV33 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa5_yeast(display_long)|uniprotkb:PUP2(gene name)|psi-mi:PUP2(display_short)|uniprotkb:DOA5(gene name synonym)|uniprotkb:YGR253C(locus name)|uniprotkb:G9155(orf name)|uniprotkb:Proteasome component PUP2(gene name synonym)|uniprotkb:Macropain subunit PUP2(gene name synonym)|uniprotkb:Proteinase YSCE subunit PUP2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y69|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|refseq:NP_011769.1|sgd:S000003485|ensemblfungi:YGR253C(gene)|ensemblfungi:YGR253C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2Z5C|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:3UN4|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QVN|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QLV|rcsb pdb:4QVY|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|mint:P32379|dip:DIP-1193N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:E8EDEB212BF4EC6E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:d9WDpDu+8VHYVXV0dRDCcL6UaSk559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P40302 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13955|ensemblfungi:YMR314W|uniprotkb:D6W0E1 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa6_yeast(display_long)|uniprotkb:PRE5(gene name)|psi-mi:PRE5(display_short)|uniprotkb:YMR314W(locus name)|uniprotkb:YM9924.06(orf name)|uniprotkb:Proteasome component PRE5(gene name synonym)|uniprotkb:Macropain subunit PRE5(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE5(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FGD|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|ensemblfungi:YMR314W(gene)|ensemblfungi:YMR314W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2Q|refseq:NP_014045.1|sgd:S000004931|mint:P40302|dip:DIP-1528N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:C43CBCC1C6B9E39E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:C9GPb0JAklkBz0t/YYqRMNEiQss559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P21242 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13963|ensemblfungi:YOR362C|uniprotkb:D6W357 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psa7_yeast(display_long)|uniprotkb:PRE10(gene name)|psi-mi:PRE10(display_short)|uniprotkb:PRC1(gene name synonym)|uniprotkb:PRS1(gene name synonym)|uniprotkb:O6650(orf name)|uniprotkb:YOR362C(locus name)|uniprotkb:Proteasome component C1(gene name synonym)|uniprotkb:Macropain subunit C1(gene name synonym)|uniprotkb:Proteinase YSCE subunit 1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 ensemblfungi:YOR362C(gene)|ensemblfungi:YOR362C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR029055|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR037555|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:1FNT|interpro:IPR023332|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QW6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4Y7Y|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5A5B|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5D0X|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L5E|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L67|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6HTC|rcsb pdb:6FVW|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6FVX|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6HV4|rcsb pdb:6G8M|rcsb pdb:6HV5|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|rcsb pdb:6HW5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:1G0U|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:3SDI|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QLS|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|refseq:NP_015007.1|sgd:S000005889|mint:P21242|dip:DIP-1526N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:1E51D904CF336747 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:tVLLjztJDttaRM40dHah/J06g0E559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P38624 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-14005|ensemblfungi:YJL001W|uniprotkb:D6VWH4 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb1_yeast(display_long)|uniprotkb:PRE3(gene name)|psi-mi:PRE3(display_short)|uniprotkb:YJL001W(locus name)|uniprotkb:J1407(orf name)|uniprotkb:Macropain subunit PRE3(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE3(gene name synonym)|uniprotkb:Proteasome component PRE3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 ensemblfungi:YJL001W(gene)|ensemblfungi:YJL001W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037559|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QV5|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:4Y8Q|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5CZ4|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5CZ5|rcsb pdb:5L52|rcsb pdb:5CZ6|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L54|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5L5Z|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:5NIF|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4QZ5|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|refseq:NP_012533.1|sgd:S000003538|mint:P38624|dip:DIP-1527N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:BD1FCE649678D86B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:CGl4wdsYSRNO3iXRKjgJw/W+qrQ559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P25043 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-14009|ensemblfungi:YOR157C|uniprotkb:D6W2L4 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb2_yeast(display_long)|uniprotkb:PUP1(gene name)|psi-mi:PUP1(display_short)|uniprotkb:YOR157C(locus name)|uniprotkb:Macropain subunit PUP1(gene name synonym)|uniprotkb:Proteinase YSCE subunit PUP1(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP1(gene name synonym)|uniprotkb:Proteasome component PUP1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000005683|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5WVK|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:6FVW|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:5MPB|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|rcsb pdb:6HW7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-174113|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QZ2|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y8M|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|ensemblfungi:YOR157C(gene)|ensemblfungi:YOR157C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|refseq:NP_014800.3|mint:P25043|dip:DIP-2818N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:13A8F2B75584539A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:tQLgAHq3RInD/qP9hIqISxdNd7w559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P25451 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13993|ensemblfungi:YER094C|uniprotkb:D3DM02 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb3_yeast(display_long)|uniprotkb:PUP3(gene name)|psi-mi:PUP3(display_short)|uniprotkb:Proteasome component PUP3(gene name synonym)|uniprotkb:YER094C(locus name)|uniprotkb:Macropain subunit PUP3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PUP3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4QWK|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|go:"GO:0004175"(endopeptidase activity)|ensemblfungi:YER094C(gene)|ensemblfungi:YER094C_mRNA(transcript)|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y80|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061133"(endopeptidase activator activity)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:2F16|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5BXN|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5FGG|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5MPC|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5NIF|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:3SDI|rcsb pdb:4INR|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4INT|rcsb pdb:4QLT|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6J2C|sgd:S000000896|refseq:NP_011020.3|mint:P25451|dip:DIP-2039N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:5AA92D746454BCB7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:T49ZHqQs5rEDpaoe/mE2E8pEeSg559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P22141 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13988|ensemblfungi:YER012W|uniprotkb:D3DLQ9 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb4_yeast(display_long)|uniprotkb:PRE1(gene name)|psi-mi:PRE1(display_short)|uniprotkb:YER012W(locus name)|uniprotkb:Proteasome component C11(gene name synonym)|uniprotkb:Macropain subunit C11(gene name synonym)|uniprotkb:Proteinase YSCE subunit 11(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C11(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|ensemblfungi:YER012W(gene)|ensemblfungi:YER012W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061133"(endopeptidase activator activity)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|refseq:NP_010928.1|sgd:S000000814|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|reactome:R-SCE-983168|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|rcsb pdb:7LSX|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|mint:P22141|dip:DIP-2808N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:ED43D319A5895B40 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:tzWxNgSLM/MVJpa7jSoNaS0I12Q559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P30656 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-14001|ensemblfungi:YPR103W|uniprotkb:D6W4A1 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb5_yeast(display_long)|uniprotkb:PRE2(gene name)|psi-mi:PRE2(display_short)|uniprotkb:DOA3(gene name synonym)|uniprotkb:PRG1(gene name synonym)|uniprotkb:YPR103W(locus name)|uniprotkb:P8283.10(orf name)|uniprotkb:Macropain subunit PRE2(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE2(gene name synonym)|uniprotkb:Proteasome component PRE2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HUV|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:6HWF|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8J|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5BXN|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5CGF|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5FGE|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L63|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4R00|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QW7|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|go:"GO:0080129"(proteasome core complex assembly)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|ensemblfungi:YPR103W(gene)|ensemblfungi:YPR103W_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3DY3|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:4Q1S|rcsb pdb:4NO9|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|refseq:NP_015428.1|sgd:S000006307|mint:P30656|dip:DIP-2806N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:D0EBAC611F7A4F37 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:brv4JvZPOIqABrJ9xWTCx+npeLs559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P23724 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13984|ensemblfungi:YBL041W|uniprotkb:D6VPV7 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb6_yeast(display_long)|uniprotkb:PRE7(gene name)|psi-mi:PRE7(display_short)|uniprotkb:PRS3(gene name synonym)|uniprotkb:PTS1(gene name synonym)|uniprotkb:YBL0407(orf name)|uniprotkb:YBL041W(locus name)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QW7|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QWI|rcsb pdb:4QWJ|rcsb pdb:4QWK|rcsb pdb:4QWL|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4QWU|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4QZ1|rcsb pdb:4QZ2|rcsb pdb:4QZ3|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QLV|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QZ7|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4X6Z|rcsb pdb:4Y69|rcsb pdb:4Y6A|rcsb pdb:4Y6V|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:4Y7X|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|ensemblfungi:YBL041W(gene)|rcsb pdb:3JCP|ensemblfungi:YBL041W_mRNA(transcript)|rcsb pdb:3MG0|go:"GO:0004175"(endopeptidase activity)|rcsb pdb:3MG4|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:3MG6|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MG7|rcsb pdb:3MG8|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|rcsb pdb:1FNT|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:2ZCY|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:4G4S|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4YA3|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|rcsb pdb:5FGD|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6G7F|rcsb pdb:5L68|rcsb pdb:6G8M|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:6H39|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HTB|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HV4|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HW7|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|rcsb pdb:6ZP6|rcsb pdb:6ZP8|rcsb pdb:7LS5|rcsb pdb:7LS6|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-69601|refseq:NP_009512.1|sgd:S000000137|mint:P23724|dip:DIP-2821N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:770A4DF1DF0A0F0E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:WzmtcPCO24lWABFyM7pXZaI9wj0559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P30657 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-13997|uniprotkb:E9P8Z8|ensemblfungi:YFR050C|uniprotkb:D6VTT3 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:psb7_yeast(display_long)|uniprotkb:PRE4(gene name)|psi-mi:PRE4(display_short)|uniprotkb:YFR050C(locus name)|uniprotkb:Macropain subunit PRE4(gene name synonym)|uniprotkb:Proteinase YSCE subunit PRE4(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit PRE4(gene name synonym)|uniprotkb:Proteasome component PRE4(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 rcsb pdb:5FGI|rcsb pdb:5FHS|rcsb pdb:5JHR|rcsb pdb:5JHS|rcsb pdb:5L52|rcsb pdb:5L54|rcsb pdb:5L55|rcsb pdb:5L5A|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5FGD|rcsb pdb:5L5U|rcsb pdb:5FGE|rcsb pdb:5FGF|rcsb pdb:5FGG|rcsb pdb:5FGH|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5NIF|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:5L60|rcsb pdb:6G7F|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:6G8M|rcsb pdb:5L64|rcsb pdb:6G8N|rcsb pdb:6GOP|rcsb pdb:5L65|rcsb pdb:5L66|rcsb pdb:5L67|rcsb pdb:6H39|rcsb pdb:5L68|rcsb pdb:5L69|rcsb pdb:5L6A|rcsb pdb:5L6B|rcsb pdb:6HTB|rcsb pdb:5L6C|rcsb pdb:5LAI|rcsb pdb:5LAJ|rcsb pdb:5LTT|rcsb pdb:6HTC|rcsb pdb:5M2B|rcsb pdb:5MP9|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HVW|rcsb pdb:6HVX|rcsb pdb:6HVY|rcsb pdb:6HW0|rcsb pdb:6HUU|rcsb pdb:6HW3|rcsb pdb:6HW4|rcsb pdb:6HW5|rcsb pdb:6HW6|rcsb pdb:6HUV|rcsb pdb:6HV3|rcsb pdb:6HW7|rcsb pdb:6HV4|rcsb pdb:6HW8|rcsb pdb:6HW9|rcsb pdb:6HV5|rcsb pdb:6HV7|rcsb pdb:6HVA|rcsb pdb:6HVR|rcsb pdb:6HVS|rcsb pdb:6HVT|rcsb pdb:6HVU|rcsb pdb:6HVV|rcsb pdb:6HWA|rcsb pdb:6HWB|rcsb pdb:6HWC|rcsb pdb:6HWD|rcsb pdb:6HWE|rcsb pdb:6HWF|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|rcsb pdb:6ZOU|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|rcsb pdb:1FNT|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|rcsb pdb:1G0U|rcsb pdb:1G65|rcsb pdb:1JD2|rcsb pdb:1RYP|rcsb pdb:1Z7Q|rcsb pdb:2F16|rcsb pdb:2FAK|rcsb pdb:2GPL|rcsb pdb:3BDM|rcsb pdb:3D29|rcsb pdb:3DY3|rcsb pdb:2ZCY|rcsb pdb:3DY4|rcsb pdb:3E47|rcsb pdb:3GPJ|rcsb pdb:3GPT|rcsb pdb:3GPW|rcsb pdb:3HYE|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:3MG0|rcsb pdb:3MG4|rcsb pdb:3MG6|rcsb pdb:3MG7|rcsb pdb:3MG8|rcsb pdb:3NZJ|rcsb pdb:3NZW|rcsb pdb:3NZX|rcsb pdb:3OEU|rcsb pdb:3OEV|rcsb pdb:3OKJ|rcsb pdb:3SDI|rcsb pdb:3SDK|rcsb pdb:3SHJ|rcsb pdb:3TDD|rcsb pdb:3UN4|rcsb pdb:3UN8|rcsb pdb:3WXR|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4EU2|rcsb pdb:4FZC|rcsb pdb:4FZG|rcsb pdb:6ZP6|rcsb pdb:4GK7|rcsb pdb:4HNP|rcsb pdb:4HRC|rcsb pdb:4HRD|rcsb pdb:4INR|rcsb pdb:4INT|rcsb pdb:4INU|rcsb pdb:4J70|rcsb pdb:4JSQ|rcsb pdb:4JSU|rcsb pdb:4JT0|rcsb pdb:4LQI|rcsb pdb:4LTC|rcsb pdb:4NNN|rcsb pdb:4NNW|rcsb pdb:4NO1|rcsb pdb:4NO6|rcsb pdb:4NO8|rcsb pdb:4NO9|rcsb pdb:4Q1S|rcsb pdb:4QBY|rcsb pdb:4QLQ|rcsb pdb:4G4S|rcsb pdb:4QLS|rcsb pdb:4QLT|rcsb pdb:4QLU|rcsb pdb:4QUX|rcsb pdb:4QUY|rcsb pdb:4QV0|rcsb pdb:4QV1|rcsb pdb:4QV3|rcsb pdb:4QV4|rcsb pdb:4QV5|rcsb pdb:4QV6|rcsb pdb:4QV7|rcsb pdb:4QV8|rcsb pdb:4QV9|rcsb pdb:4QVL|rcsb pdb:4QVM|rcsb pdb:4QVN|rcsb pdb:4QVP|rcsb pdb:4QVQ|rcsb pdb:4QVV|rcsb pdb:4QVW|rcsb pdb:4QVY|rcsb pdb:4QW0|rcsb pdb:4QW1|rcsb pdb:4QW3|rcsb pdb:4QW4|rcsb pdb:4QW5|rcsb pdb:4QW6|rcsb pdb:4QLV|rcsb pdb:4QZ2|rcsb pdb:4QW7|rcsb pdb:4QZ3|rcsb pdb:4QZ4|rcsb pdb:4QZ5|rcsb pdb:4QZ6|rcsb pdb:4QWF|rcsb pdb:4QWG|rcsb pdb:4QZ7|rcsb pdb:4QWI|rcsb pdb:4QZW|rcsb pdb:4QZX|rcsb pdb:4QZZ|rcsb pdb:4R00|rcsb pdb:4QWJ|rcsb pdb:4R02|rcsb pdb:4R17|rcsb pdb:4R18|rcsb pdb:4QWK|rcsb pdb:4RUR|rcsb pdb:4V7O|rcsb pdb:4QWL|rcsb pdb:4X6Z|rcsb pdb:4QWR|rcsb pdb:4QWS|rcsb pdb:4Y69|rcsb pdb:4QWU|rcsb pdb:4Y6A|rcsb pdb:4QWX|rcsb pdb:4QXJ|rcsb pdb:4QZ0|rcsb pdb:4Y6V|rcsb pdb:4QZ1|rcsb pdb:4Y6Z|rcsb pdb:4Y70|rcsb pdb:4Y74|rcsb pdb:4Y75|rcsb pdb:4Y77|rcsb pdb:4Y78|rcsb pdb:4Y7W|rcsb pdb:6ZP8|rcsb pdb:7LS5|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|rcsb pdb:4Y7Y|rcsb pdb:4Y80|rcsb pdb:4Y81|rcsb pdb:4Y82|rcsb pdb:4Y84|rcsb pdb:4Y8G|rcsb pdb:4Y8H|rcsb pdb:4Y8I|rcsb pdb:4Y8J|rcsb pdb:4Y8K|rcsb pdb:4Y8L|rcsb pdb:4Y8M|rcsb pdb:4Y8N|rcsb pdb:4Y8O|rcsb pdb:4Y8P|rcsb pdb:4Y8Q|rcsb pdb:4Y8R|rcsb pdb:4Y8S|rcsb pdb:4Y8T|rcsb pdb:4Y8U|rcsb pdb:4Y9Y|rcsb pdb:4Y9Z|rcsb pdb:4YA0|rcsb pdb:4YA1|rcsb pdb:4YA2|rcsb pdb:4Y7X|rcsb pdb:4YA4|rcsb pdb:4YA5|rcsb pdb:4YA7|rcsb pdb:4YA9|rcsb pdb:4Z1L|rcsb pdb:5A5B|rcsb pdb:5AHJ|rcsb pdb:5BOU|rcsb pdb:5BXL|rcsb pdb:5BXN|rcsb pdb:5CGF|rcsb pdb:5CGG|rcsb pdb:5CGH|rcsb pdb:5CGI|rcsb pdb:5CZ4|rcsb pdb:5CZ5|rcsb pdb:5CZ6|rcsb pdb:5CZ7|rcsb pdb:5CZ8|rcsb pdb:5CZ9|rcsb pdb:5CZA|rcsb pdb:5D0S|rcsb pdb:5D0T|rcsb pdb:5D0V|rcsb pdb:5D0W|rcsb pdb:5D0X|rcsb pdb:5D0Z|rcsb pdb:5DKI|rcsb pdb:4YA3|rcsb pdb:5DKJ|rcsb pdb:5FG7|rcsb pdb:5FG9|rcsb pdb:5FGA|ensemblfungi:YFR050C(gene)|ensemblfungi:YFR050C_mRNA(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|refseq:NP_116708.1|sgd:S000001946|mint:P30657|dip:DIP-2807N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:E585BB3B5D0C8E2C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:y7+7rEZc9fqBZrHR4CvsFLoT0O4559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P38886 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15949|ensemblfungi:YHR200W|uniprotkb:D3DLE9 psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn10_yeast(display_long)|uniprotkb:RPN10(gene name)|psi-mi:RPN10(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:SUN1(gene name synonym)|uniprotkb:YHR200W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 ensemblfungi:YHR200W(gene)|ensemblfungi:YHR200W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|sgd:S000001243|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR027040|interpro:IPR036465|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5LN1|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_012070.3|dip:DIP-2100N|mint:P38886 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:8A05198B0CD7C0C3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:Lg2bjPWMUcvXdLDZZMWFWyXbCcA559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P43588 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-11219|uniprotkb:Q8J0T5|uniprotkb:D6VTN4|ensemblfungi:YFR004W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn11_yeast(display_long)|uniprotkb:YFR004W(locus name)|uniprotkb:RPN11(gene name)|psi-mi:RPN11(display_short)|uniprotkb:MPR1(gene name synonym)|uniprotkb:Protein MPR1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 ensemblfungi:YFR004W(gene)|ensemblfungi:YFR004W_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016559"(peroxisome fission)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070628"(proteasome binding)|go:"GO:1902906"(proteasome storage granule assembly)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|go:"GO:0070122"(isopeptidase activity)|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_116659.1|sgd:S000001900|mint:P43588|dip:DIP-1573N psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:9DDE8BD74890894D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:f3lAMY9siMcO2dAOfKvVrvKzfNM559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P32496 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15953|uniprotkb:D6VTT5|ensemblfungi:YFR052W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn12_yeast(display_long)|uniprotkb:RPN12(gene name)|psi-mi:RPN12(display_short)|uniprotkb:NIN1(gene name synonym)|uniprotkb:Nuclear integrity protein 1(gene name synonym)|uniprotkb:YFR052W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_116710.1|sgd:S000001948|ensemblfungi:YFR052W(gene)|ensemblfungi:YFR052W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|rcsb pdb:3J47|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:3JCK|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:3JCO|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:3JCP|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:4CR2|dip:DIP-1575N|mint:P32496 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:D901AAD4D07ED3D1 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:CfJpK67fHH3iGDxduaRg+z2hokY559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:O13563 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-32948|uniprotkb:D6VZ57|ensemblfungi:YLR421C psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn13_yeast(display_long)|uniprotkb:RPN13(gene name)|psi-mi:RPN13(display_short)|uniprotkb:DAQ1(gene name synonym)|uniprotkb:Proteasome non-ATPase subunit 13(gene name synonym)|uniprotkb:YLR421C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000004413|refseq:NP_013525.3|mint:O13563|dip:DIP-4637N|ensemblfungi:YLR421C(gene)|ensemblfungi:YLR421C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR038633|interpro:IPR044868|rcsb pdb:2Z4D|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:752E8A12DC3799D4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:UDb5Hp4hH3QQ5iX7/9BtQVBO0FA559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P32565 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15919|uniprotkb:D6VVK9|ensemblfungi:YIL075C psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn2_yeast(display_long)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)|uniprotkb:SEN3(gene name synonym)|uniprotkb:YIL075C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_012190.1|sgd:S000001337|ensemblfungi:YIL075C(gene)|ensemblfungi:YIL075C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4ADY|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-4638N|mint:P32565 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:881E78EBC6BD934F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:XKuDty+1gX7/pz7ZtNmYK4Pfkc8559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:P40016 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15927|uniprotkb:D3DLS0|ensemblfungi:YER021W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn3_yeast(display_long)|uniprotkb:RPN3(gene name)|psi-mi:RPN3(display_short)|uniprotkb:SUN2(gene name synonym)|uniprotkb:YER021W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_010938.1|sgd:S000000823|ensemblfungi:YER021W(gene)|ensemblfungi:YER021W_mRNA(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1322N|mint:P40016 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:B08B58663DDA85DC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:pXkyoZKr0rI5usi19R+TvS4hSso559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:Q12250 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15935|uniprotkb:D6VRK1|ensemblfungi:YDL147W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn5_yeast(display_long)|uniprotkb:RPN5(gene name)|psi-mi:RPN5(display_short)|uniprotkb:NAS5(gene name synonym)|uniprotkb:YDL147W(locus name)|uniprotkb:D1572(orf name)|uniprotkb:Proteasome non-ATPase subunit 5(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_010134.1|sgd:S000002306|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:5ZMR|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:6FVX|ensemblfungi:YDL147W(gene)|ensemblfungi:YDL147W_mRNA(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034515"(proteasome storage granule)|rcsb pdb:6J2C|rcsb pdb:6FVY|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|dip:DIP-1578N|mint:Q12250 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:E5DC7F8E6AE27736 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:DaeRxapE6TgoZG4emWRb3y12Vfc559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:Q12377 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-308|uniprotkb:D6VRQ3|ensemblfungi:YDL097C psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn6_yeast(display_long)|uniprotkb:RPN6(gene name)|psi-mi:RPN6(display_short)|uniprotkb:NAS4(gene name synonym)|uniprotkb:YDL097C(locus name)|uniprotkb:D2381(orf name)|uniprotkb:Proteasome non-ATPase subunit 4(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_010186.1|sgd:S000002255|dip:DIP-1581N|mint:Q12377|ensemblfungi:YDL097C(gene)|ensemblfungi:YDL097C_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:A8B1F7E6F73A4024 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:Q7d0N0C4nR9dUZHh+zofzWAF/t8559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:Q06103 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15940|uniprotkb:D6W4A6|uniprotkb:E9P8W9|ensemblfungi:YPR108W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn7_yeast(display_long)|uniprotkb:RPN7(gene name)|psi-mi:RPN7(display_short)|uniprotkb:P8283.8(orf name)|uniprotkb:YPR108W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 refseq:NP_015433.1|sgd:S000006312|ensemblfungi:YPR108W(gene)|ensemblfungi:YPR108W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR019734|interpro:IPR035268|interpro:IPR036390|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|rcsb pdb:3J47|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|rcsb pdb:3JCK|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|dip:DIP-2880N|mint:Q06103 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:B21B66CD818E636D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:RVj0KoFtiJVk9oF3cYIftSVLejc559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:Q08723 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-36176|uniprotkb:Q6Q5I7|uniprotkb:D6W2W2|ensemblfungi:YOR261C psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn8_yeast(display_long)|uniprotkb:RPN8(gene name)|psi-mi:RPN8(display_short)|uniprotkb:O5360(orf name)|uniprotkb:YOR261C(locus name) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000005787|refseq:NP_014904.3|mint:Q08723|dip:DIP-1574N|ensemblfungi:YOR261C(gene)|ensemblfungi:YOR261C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070122"(isopeptidase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:4O8X|rcsb pdb:4O8Y|rcsb pdb:4OCL|rcsb pdb:4OCM|rcsb pdb:4OCN|rcsb pdb:4OWP|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5U4P|rcsb pdb:5W83|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:6EE6009545A3D0EF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:kvJ/LyyQGKi5JTh4Fek1kh70jOU559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53549 uniprotkb:Q04062 intact:EBI-18520|uniprotkb:Q08718|uniprotkb:D6W2W0|ensemblfungi:YOR259C intact:EBI-15944|uniprotkb:D6VT56|ensemblfungi:YDR427W psi-mi:prs10_yeast(display_long)|uniprotkb:RPT4(gene name)|psi-mi:RPT4(display_short)|uniprotkb:CRL13(gene name synonym)|uniprotkb:PCS1(gene name synonym)|uniprotkb:SUG2(gene name synonym)|uniprotkb:26S protease subunit SUG2(gene name synonym)|uniprotkb:Proteasomal cap subunit(gene name synonym)|uniprotkb:YOR259C(locus name) psi-mi:rpn9_yeast(display_long)|uniprotkb:RPN9(gene name)|psi-mi:RPN9(display_short)|uniprotkb:NAS7(gene name synonym)|uniprotkb:YDR427W(locus name)|uniprotkb:D9461.14(orf name)|uniprotkb:Proteasome non-ATPase subunit 7(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Beck et al. (2012) pubmed:22927375|doi:10.1073/pnas.1213333109|imex:IM-20708 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16011601|imex:IM-20708-1|dip:DIP-190361E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005785|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|rcsb pdb:5MPB|ensemblfungi:YOR259C(gene)|ensemblfungi:YOR259C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|refseq:NP_014902.3|dip:DIP-1589N|mint:P53549 sgd:S000002835|ensemblfungi:YDR427W(gene)|ensemblfungi:YDR427W_mRNA(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0043248"(proteasome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|interpro:IPR040798|rcsb pdb:2MQW|rcsb pdb:2MR3|rcsb pdb:2MRI|rcsb pdb:3J47|rcsb pdb:3JCK|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5MPD|rcsb pdb:5MPE|rcsb pdb:5WVI|rcsb pdb:5WVK|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-6798695|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8948751|reactome:R-SCE-983168|refseq:NP_010715.3|dip:DIP-5261N|mint:Q04062 psi-mi:"MI:0465"(dip) crc64:0EA42A599E2B2E2A crc64:540F7DF8C23469A1 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/07 2017/08/10 rogid:ZWrHVXeF+u+1NSq2hgELa61z4UE559292 rogid:hOAU0IY1VeRlmtX4Dw3MNJybZaE559292 rigid:yNQBo8RO+G88B4h3XnEfgdoCcP8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)