#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H8H0	uniprotkb:Q969X6	intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name)	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915911|imex:IM-25680-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	-	-	-	figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/16	2017/02/16	rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rigid:CD6EfBh2E0JJ+utY7gzBCDTqXoM	false	sufficient binding region:536-719	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H8H0	uniprotkb:Q969X6	intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name)	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915923|imex:IM-25680-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	-	-	comment:"UTP4 mutant arg565trp does interact (in context of full length protein)"	figure legend:1B, 7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/16	2017/02/16	rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rigid:CD6EfBh2E0JJ+utY7gzBCDTqXoM	false	sufficient binding region:536-719	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H8H0	uniprotkb:Q969X6	intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name)	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915959|imex:IM-25680-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	-	-	-	figure legend:7C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/16	2017/02/16	rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rigid:CD6EfBh2E0JJ+utY7gzBCDTqXoM	false	-	necessary binding region:558-686	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H8H0	uniprotkb:Q969X6	intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name)	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915967|imex:IM-25680-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	-	-	-	figure legend:7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/02/16	2017/02/16	rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rigid:CD6EfBh2E0JJ+utY7gzBCDTqXoM	false	-	mutation decreasing interaction strength:565-565|sufficient binding region:374-686	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969X6	uniprotkb:Q15061	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	intact:EBI-2563523|uniprotkb:Q92577|uniprotkb:Q15395|ensembl:ENSP00000384302	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:wdr43_human(display_long)|uniprotkb:WDR43(gene name)|psi-mi:WDR43(display_short)|uniprotkb:KIAA0007(gene name synonym)|uniprotkb:UTP5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 5 homolog(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915938|imex:IM-25680-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	refseq:NP_055946.1|ensembl:ENSG00000163811(gene)|ensembl:ENST00000407426(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q15061|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Table 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2017/02/16	2017/02/16	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rogid:5YWzMczifqbhFvvX1HkF3XYW6xA9606	rigid:uqNksRO5TkBSM+vgSTTzgul/Kus	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q969X6	uniprotkb:Q8IWA0	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	intact:EBI-2515097|ensembl:ENSP00000314193|uniprotkb:Q9UIX2|uniprotkb:Q9H9U5|uniprotkb:Q96J10|uniprotkb:Q9H8U8|uniprotkb:Q9H9V8	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:wdr75_human(display_long)|uniprotkb:WDR75(gene name)|psi-mi:WDR75(display_short)|uniprotkb:UTP17(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 17 homolog(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915938|imex:IM-25680-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	ensembl:ENSG00000115368(gene)|ensembl:ENST00000314761(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_115544.1|refseq:NP_001290025.1	-	-	-	figure legend:Table 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2017/02/16	2017/02/16	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rogid:qAYPzmryYALOzvea97t1q/NCsVs9606	rigid:uqNksRO5TkBSM+vgSTTzgul/Kus	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q969X6	uniprotkb:Q8TED0	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	intact:EBI-1048301|uniprotkb:Q6IA60|uniprotkb:Q96E08|uniprotkb:Q9H9F8|uniprotkb:B4DU75|uniprotkb:B4DXK8|ensembl:ENSP00000296792	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:utp15_human(display_long)|uniprotkb:UTP15(gene name)|psi-mi:UTP15(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915938|imex:IM-25680-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	refseq:NP_001271359.1|refseq:NP_001271360.1|refseq:NP_115551.2|refseq:XP_011541982.1|ensembl:ENSG00000164338(gene)|ensembl:ENST00000296792(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006364"(rRNA processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018983|interpro:IPR019775|interpro:IPR036322|mint:Q8TED0|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Table 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2017/02/16	2017/02/16	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rogid:acCnB6DdQIhfvM1C9EQVQdoqHvo9606	rigid:uqNksRO5TkBSM+vgSTTzgul/Kus	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q969X6	uniprotkb:Q9H8H0	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name)	psi-mi:"MI:0676"(tandem affinity purification)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915938|imex:IM-25680-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:Table 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2017/02/16	2017/02/16	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606	rigid:uqNksRO5TkBSM+vgSTTzgul/Kus	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q969X6	uniprotkb:Q562E7	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	intact:EBI-5235360|uniprotkb:Q24JP6|uniprotkb:Q8N277|uniprotkb:Q8N3F3|uniprotkb:B3KW16|uniprotkb:B3KXU1|uniprotkb:B7Z579|uniprotkb:E9PHG7|uniprotkb:Q8TEL1|ensembl:ENSP00000386609	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:wdr81_human(display_long)|uniprotkb:WDR81(gene name)|psi-mi:WDR81(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915938|imex:IM-25680-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	refseq:XP_011521953.1|refseq:NP_001157145.1|refseq:NP_001157281.1|refseq:NP_001157283.1|refseq:NP_689561.2|ensembl:ENSG00000167716(gene)|ensembl:ENST00000409644(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035973"(aggrephagy)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR036372|reactome:R-HSA-9013148|go:"GO:0045022"(early endosome to late endosome transport)	-	-	-	figure legend:Table 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2017/02/16	2017/02/16	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rogid:WZMmbrspcu0HwOC1iuqrGa4NA2s9606	rigid:uqNksRO5TkBSM+vgSTTzgul/Kus	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q969X6	uniprotkb:P48740	intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13	intact:EBI-6380536|ensembl:ENSP00000336792|uniprotkb:A8K542|uniprotkb:A8K6M1|uniprotkb:B4E2L7|uniprotkb:O95570|uniprotkb:Q68D21|uniprotkb:Q8IUV8|uniprotkb:Q96RS4|uniprotkb:Q9UF09	psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym)	psi-mi:masp1_human(display_long)|uniprotkb:MASP1(gene name)|psi-mi:MASP1(display_short)|uniprotkb:CRARF(gene name synonym)|uniprotkb:CRARF1(gene name synonym)|uniprotkb:PRSS5(gene name synonym)|uniprotkb:Complement factor MASP-3(gene name synonym)|uniprotkb:Complement-activating component of Ra-reactive factor(gene name synonym)|uniprotkb:Mannose-binding lectin-associated serine protease 1(gene name synonym)|uniprotkb:Mannose-binding protein-associated serine protease(gene name synonym)|uniprotkb:Ra-reactive factor serine protease p100(gene name synonym)|uniprotkb:Serine protease 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915938|imex:IM-25680-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2	refseq:XP_016862361.1|ensembl:ENSG00000127241(gene)|ensembl:ENST00000337774(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008233"(peptidase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045916"(negative regulation of complement activation)|go:"GO:0048306"(calcium-dependent protein binding)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000859(CUB)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035914|interpro:IPR035976|interpro:IPR043504|rcsb pdb:3DEM|rcsb pdb:3GOV|rcsb pdb:4AQB|rcsb pdb:4DJZ|rcsb pdb:4IGD|rcsb pdb:4IW4|rcsb pdb:4KKD|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-3000480|dip:DIP-61382N|refseq:NP_001027019.1|refseq:NP_001870.3|refseq:NP_624302.1	-	-	-	figure legend:Table 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens)	-	2017/02/16	2017/02/16	rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606	rogid:Yqzsp6f/Mg3AyvyK42mX/kQ3s389606	rigid:uqNksRO5TkBSM+vgSTTzgul/Kus	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9H8H0	uniprotkb:P22087	intact:EBI-725885|uniprotkb:Q7L5S1|uniprotkb:Q9UG18|uniprotkb:B7Z5V9|ensembl:ENSP00000253247	intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8	psi-mi:nol11_human(display_long)|uniprotkb:NOL11(gene name)|psi-mi:NOL11(display_short)|uniprotkb:L14(orf name)	psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Freed et al. (2011)	imex:IM-25680|pubmed:22916032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13915954|imex:IM-25680-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056277.2|refseq:NP_001290201.1|ensembl:ENSG00000130935(gene)|ensembl:ENST00000253247(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0034455"(t-UTP complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|interpro:IPR012584(NUC205)|interpro:IPR036322|interpro:IPR042859|reactome:R-HSA-6790901|reactome:R-HSA-6791226	refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N	-	-	-	figure legend:3|antagonist:"actinomycin D (ActD); transcription inhibitor"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/02/16	2017/02/27	rogid:DerJ7iPKNSsk7il8nQJQUQn6uCw9606	rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606	rigid:zjKWQwKqe7e9X1J0wvh+C0A2HFc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)